Monika Schmelz

  • 1743 Citations
  • 20 h-Index
1986 …2018
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Research Output 1986 2018

  • 1743 Citations
  • 20 h-Index
  • 35 Article
  • 1 Conference contribution
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Article
2018
4 Citations (Scopus)

Phase I Study of the Investigational Aurora A Kinase Inhibitor Alisertib plus Rituximab or Rituximab/Vincristine in Relapsed/Refractory Aggressive B-cell Lymphoma

Kelly, K. R., Friedberg, J. W., Park, S. I., McDonagh, K., Hayslip, J., Persky, D., Ruan, J., Puvvada, S. D., Rosen, P., Iyer, S. P., Stefanovic, A., Bernstein, S. H., Weitman, S., Karnad, A., Monohan, G., VanderWalde, A., Mena, R., Schmelz, M., Perry, C. S., Groshen, S. & 5 others, Venkatakrishnan, K., Zhou, X., Sheldon-Waniga, E., Jane Leonard, E. & Mahadevan, D., Dec 15 2018, In : Clinical Cancer Research. 24, 24, p. 6150-6159 10 p.

Research output: Contribution to journalArticle

Aurora Kinase A
Vincristine
B-Cell Lymphoma
Non-Hodgkin's Lymphoma
Lymphoma, Large B-Cell, Diffuse
2017
5 Citations (Scopus)

Aberrant cytoplasmic expression of MHCII confers worse progression free survival in diffuse large B-cell lymphoma

Kendrick, S., Rimsza, L. M., Scott, D. W., Slack, G. W., Farinha, P., Tan, K. L., Persky, D., Puvvada, S. D., Connors, J. M., Sehn, L., Gascoyne, R. D. & Schmelz, M., Jan 1 2017, In : Virchows Archiv. 470, 1, p. 113-117 5 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)

A Phase II Exploratory Study of PXD-101 (Belinostat) Followed by Zevalin in Patients with Relapsed Aggressive High-Risk Lymphoma

Puvvada, S. D., Guillén-Rodríguez, J. M., Rivera, X. I., Heard, K., Inclan, L., Schmelz, M., Schatz, J. H. & Persky, D. O., Sep 5 2017, (Accepted/In press) In : Oncology (Switzerland).

Research output: Contribution to journalArticle

Lymphoma
Lymphoma, Large B-Cell, Diffuse
Major Histocompatibility Complex
Biomarkers
Histone Deacetylases
1 Citation (Scopus)

Come in Out of the Cold: Alternatives to Freezing for Microbial Biorepositories

Isaacs, E. & Schmelz, M., Feb 15 2017, In : Clinical Microbiology Newsletter. 39, 4, p. 27-34 8 p.

Research output: Contribution to journalArticle

Nucleic Acids
Freezing
Technology
Costs and Cost Analysis
Quality Control
3 Citations (Scopus)

Pak2 regulates myeloid-derived suppressor cell development in mice

Zeng, Y., Hahn, S., Stokes, J., Hoffman, E. A., Schmelz, M., Proytcheva, M., Chernoff, J. & Katsanis, E., Oct 10 2017, In : Blood Advances. 1, 22, p. 1923-1933 11 p.

Research output: Contribution to journalArticle

Hematopoietic Stem Cells
Granulocyte-Macrophage Colony-Stimulating Factor
p21-Activated Kinases
T-Lymphocytes
Cell Proliferation
2016
16 Citations (Scopus)

A phase II study of belinostat (PXD101) in relapsed and refractory aggressive B-cell lymphomas: SWOG S0520

Puvvada, S. D., Li, H., Rimsza, L. M., Bernstein, S. H., Fisher, R. I., LeBlanc, M., Schmelz, M., Glinsmann-Gibson, B., Miller, T. P., Maddox, A. M., Friedberg, J. W., Smith, S. M. & Persky, D. O., Jan 12 2016, (Accepted/In press) In : Leukemia and Lymphoma. p. 1-11 11 p.

Research output: Contribution to journalArticle

Histocompatibility Antigens Class II
B-Cell Lymphoma
Tumor-Infiltrating Lymphocytes
T-Lymphocytes
Tumor Microenvironment
9 Citations (Scopus)

Belinostat and vincristine demonstrate mutually synergistic cytotoxicity associated with mitotic arrest and inhibition of polyploidy in a preclinical model of aggressive diffuse large B cell lymphoma

Havas, A. P., Rodrigues, K. B., Bhakta, A., Demirjian, J. A., Hahn, S., Tran, J., Scavello, M., Tula-Sanchez, A. A., Zeng, Y. ., Schmelz, M. & Smith, C., Dec 1 2016, In : Cancer Biology and Therapy. 17, 12, p. 1240-1252 13 p.

Research output: Contribution to journalArticle

Histone Deacetylase Inhibitors
Polyploidy
Lymphoma, Large B-Cell, Diffuse
Vincristine
Cell Line
3 Citations (Scopus)

Langerhans cell histiocytosis shows distinct cytoplasmic expression of major histocompatibility class II antigens

Redd, L., Schmelz, M., Burack, W. R., Cook, J. R., Day, A. W. & Rimsza, L. M., Sep 1 2016, In : Journal of Hematopathology. 9, 3, p. 107-112 6 p.

Research output: Contribution to journalArticle

Langerhans Cell Histiocytosis
Histocompatibility
Histocompatibility Antigens Class II
Staining and Labeling
HLA-DR Antigens
2012
6 Citations (Scopus)

Lack and/or aberrant localization of major histocompatibility class II (MHCII) protein in plasmablastic lymphoma

Schmelz, M., Montes-Moreno, S., Piris, M., Wilkinson, S. T. & Rimsza, L. M., Oct 1 2012, In : Haematologica. 97, 10, p. 1614-1616 3 p.

Research output: Contribution to journalArticle

CD8 Antigens
Histocompatibility
Histocompatibility Antigens Class II
B-Cell Lymphoma
HLA-DR Antigens
2010
26 Citations (Scopus)

Prognostic Criteria for Squamous Cell Cancer of the Skin

Jensen, V., Rama Rao, A. P., Smith, A., Raju, M., Wendel, C. S., Schmelz, M., Leyva, W., Warneke, J. A. & Krouse, R. S., Mar 2010, In : Journal of Surgical Research. 159, 1, p. 509-516 8 p.

Research output: Contribution to journalArticle

Squamous Cell Neoplasms
Skin Neoplasms
Squamous Cell Carcinoma
Neoplasms
Cyclin D1
2009
27 Citations (Scopus)

Implantation of a three-dimensional fibroblast matrix improves left ventricular function and blood flow after acute myocardial infarction

Thai, H. M., Juneman, E. B., Lancaster, J., Hagerty, T., Do, R., Castellano, L., Kellar, R., Williams, S., Sethi, G., Schmelz, M., Gaballa, M. & Goldman, S., 2009, In : Cell Transplantation. 18, 3, p. 283-295 13 p.

Research output: Contribution to journalArticle

Fibroblasts
Left Ventricular Function
Blood
Myocardial Infarction
Ventricular Pressure
2006
13 Citations (Scopus)

Integrin-dependent amplification of the G2 arrest induced by ionizing radiation

Kremer, C. L., Schmelz, M. & Cress, A. E., Jan 1 2006, In : Prostate. 66, 1, p. 88-96 9 p.

Research output: Contribution to journalArticle

Ionizing Radiation
Integrins
Prostatic Intraepithelial Neoplasia
Epithelial Cells
DNA Damage
2005
24 Citations (Scopus)

Cellular immune suppressor activity resides in lymphocyte cell clusters adjacent to granulomata in human coccidioidomycosis

Li, L., Dial, S. M., Schmelz, M., Rennels, M. A. & Ampel, N. M., Jul 2005, In : Infection and Immunity. 73, 7, p. 3923-3928 6 p.

Research output: Contribution to journalArticle

Coccidioidomycosis
Granuloma
Interleukin-10
Lymphocytes
T-Lymphocytes
26 Citations (Scopus)

Identification of a stem cell candidate in the normal human prostate gland

Schmelz, M., Moll, R., Hesse, U., Rama Rao, A. P., Gandolfi, A. J., Hasan, S. R., Bartholdi, M. & Cress, A. E., Mar 9 2005, In : European Journal of Cell Biology. 84, 2-3, p. 341-354 14 p.

Research output: Contribution to journalArticle

Prostate
Stem Cells
Keratin-6
Organ Culture Techniques
Epithelial Cells
2004

Erratum: PEAZ-1: A new human prostate neoplastic epithelial cell line (Prostate (2001) 48 (79-92))

Schmelz, M., Cress, A. E., Barrera, J., McDaniel, K. M., Davis, T. L., Fuchs, L., Dalkin, B. L. & Nagle, R. B., Dec 1 2004, In : Prostate. 61, 4, p. 375 1 p.

Research output: Contribution to journalArticle

9 Citations (Scopus)

Immunohistochemical comparison of vascular and sinusoidal adherens junctions in cavernosal endothelium

Wessells, H., King, S. H., Schmelz, M., Nagle, R. B. & Heimark, R. L., Jan 2004, In : Urology. 63, 1, p. 201-206 6 p.

Research output: Contribution to journalArticle

Adherens Junctions
Vinculin
Endothelium
Blood Vessels
Arterioles
2002
62 Citations (Scopus)

Different phenotypes in human prostate cancer: α6 or α3 integrin in cell-extracellular adhesion sites

Schmelz, M., Cress, A. E., Scott, K. M., Bürgery, F., Cui, H., Sallam, K., McDaniel, K. M., Dalkin, B. L. & Nagle, R. B., 2002, In : Neoplasia. 4, 3, p. 243-254 12 p.

Research output: Contribution to journalArticle

Cell Adhesion
Integrins
Prostatic Neoplasms
Phenotype
Neoplasm Grading
2001
120 Citations (Scopus)

In vitro dorsal root ganglia and human prostate cell line interaction: Redefining perineural invasion in prostate cancer

Ayala, G. E., Wheeler, T. M., David Shine, H., Schmelz, M., Frolov, A., Chakraborty, S. & Rowley, D., 2001, In : Prostate. 49, 3, p. 213-223 11 p.

Research output: Contribution to journalArticle

Spinal Ganglia
Neurites
Cell Communication
Prostate
Prostatic Neoplasms
8 Citations (Scopus)

PEAZ-1: A new human prostate neoplastic epithelial cell line

Schmelz, M., Cress, A. E., Barrera, J., McDaniel, K. M., Davis, T. L., Fuchs, L., Dalkin, B. L. & Nagle, R. B., Jul 1 2001, In : Prostate. 48, 2, p. 79-92 14 p.

Research output: Contribution to journalArticle

Prostate
Epithelial Cells
Cell Line
Cadherins
gamma Catenin
21 Citations (Scopus)

Selective disruption of cadherin/catenin complexes by oxidative stress in precision-cut mouse liver slices

Schmelz, M., Schmid, V. J. & Parrish, A. R., 2001, In : Toxicological Sciences. 61, 2, p. 389-394 6 p.

Research output: Contribution to journalArticle

Catenins
Oxidative stress
Cadherins
Liver
Oxidative Stress
95 Citations (Scopus)

Signal transduction through the Ras/Erk pathway is essential for the mycoestrogen Zearalenone-induced cell-cycle progression in MCF-7 cells

Calaluce, R., Kunkel, M. W., Watts, G. S., Schmelz, M., Hao, J., Barrera, J., Gleason-Guzman, M., Isett, R., Fitchmun, M., Tim Bowden, G., Cress, A. E., Futscher, B. W. & Nagle, R. B., 2001, In : Molecular Carcinogenesis. 30, 2, p. 88-98 11 p.

Research output: Contribution to journalArticle

Zearalenone
MCF-7 Cells
Signal Transduction
Cell Cycle
G2 Phase
1999
60 Citations (Scopus)

Drebrin is a widespread actin-associating protein enriched at junctional plaques, defining a specific microfilament anchorage system in polar epithelial cells

Peitsch, W. K., Grund, C., Kuhn, C., Schnölzer, M., Spring, H., Schmelz, M. & Franke, W. W., 1999, In : European Journal of Cell Biology. 78, 11, p. 767-778 12 p.

Research output: Contribution to journalArticle

Polar Bodies
Actin Cytoskeleton
Actins
Epithelial Cells
Vinculin
1998
9 Citations (Scopus)

A novel type of adhering junction in an epithelioid tumorigenic rat cell culture line

Schmelz, M., Way, D. L., Borgs, P., Peitsch, W. K., Schmidt, H., Witte, M. H., Witte, C. L., Franke, W. W. & Moll, R., 1998, In : Cell & Tissue Research. 294, 1, p. 11-25 15 p.

Research output: Contribution to journalArticle

Cell culture
Cadherins
Rats
Cell Culture Techniques
Cell Line
1996
32 Citations (Scopus)

Differences of bcl-2 protein expression between Merkel cells and Merkel cell carcinomas

Moll, I., Gillardon, F., Waltering, S., Schmelz, M. & Moll, R., Apr 1996, In : Journal of Cutaneous Pathology. 23, 2, p. 109-117 9 p.

Research output: Contribution to journalArticle

Merkel Cells
Merkel Cell Carcinoma
Proteins
Melanocytes
bcl-2 Genes
1 Citation (Scopus)

Isolation and characterization of a new established human lymphatic endothelial cell line (HTDEC-1)

Way, D., Borgs, P., Witte, M. H., Schmelz, M., Sobonya, R. E., Shao, X. & Witte, C., 1996, In : Lymphology. 29, SUPPL., p. 176-178 3 p.

Research output: Contribution to journalArticle

63 Citations (Scopus)

Proliferative merkel cells were not detected in human skin

Moll, I., Zieger, W. & Schmelz, M., Apr 1996, In : Archives of Dermatological Research. 288, 4, p. 184-187 4 p.

Research output: Contribution to journalArticle

Merkel Cells
Skin
Keratins
Keratinocytes
Neuroendocrine Cells
1994
299 Citations (Scopus)

Assembly of vaccinia virus: The second wrapping cisterna is derived from the trans Golgi network

Schmelz, M., Sodeik, B., Ericsson, M., Wolffe, E. J., Shida, H., Hiller, G. & Griffiths, G., Jan 1994, In : Journal of Virology. 68, 1, p. 130-147 18 p.

Research output: Contribution to journalArticle

trans-Golgi Network
Vaccinia virus
Viruses
viruses
endosomes
98 Citations (Scopus)

Complexus adhaerentes, a new group of desmoplakin-containing junctions in endothelial cells: II. Different types of lymphatic vessels

Schmelz, M., Moll, R., Kuhn, C. & Franke, W. W., 1994, In : Differentiation. 57, 2, p. 97-117 21 p.

Research output: Contribution to journalArticle

Desmoplakins
Lymphatic Vessels
Endothelial Cells
Desmocollins
Desmogleins
1993
103 Citations (Scopus)
Desmoplakins
Endothelial Cells
Lymph Nodes
gamma Catenin
Desmosomes
1991
44 Citations (Scopus)

Amino acid sequence of bovine muzzle epithelial desmocollin derived from cloned cDNA: A novel subtype of desmosomal cadherins

Koch, P. J., Goldschmidt, M. D., Walsh, M. J., Zimbelmann, R., Schmelz, M. & Franke, W. W., 1991, In : Differentiation. 47, 1, p. 29-36 8 p.

Research output: Contribution to journalArticle

Desmosomal Cadherins
Desmocollins
Amino Acid Sequence
Complementary DNA
Desmosomes
146 Citations (Scopus)

Endocytosis of junctional cadherins in bovine kidney epithelial (MDBK) cells cultured in low Ca2+ ion medium

Kartenbeck, J., Schmelz, M., Franke, W. W. & Geiger, B., May 1991, In : Journal of Cell Biology. 113, 4, p. 881-892 12 p.

Research output: Contribution to journalArticle

Cadherins
Endocytosis
Epithelial Cells
Ions
Kidney
1990
248 Citations (Scopus)

Identification of desmoglein, a constitutive desmosomal glycoprotein, as a member of the cadherin family of cell adhesion molecules

Koch, P. J., Walsh, M. J., Schmelz, M., Goldschmidt, M. D., Zimbelmann, R. & Franke, W. W., 1990, In : European Journal of Cell Biology. 53, 1, p. 1-12 12 p.

Research output: Contribution to journalArticle

Desmogleins
Cell Adhesion Molecules
Cadherins
Glycoproteins
Amino Acids
1987
33 Citations (Scopus)

The desmosomal plaque and the cytoskeleton.

Franke, W. W., Cowin, P., Schmelz, M. & Kapprell, H. P., 1987, In : Ciba Foundation symposium. 125, p. 26-48 23 p.

Research output: Contribution to journalArticle

Intermediate Filaments
Cytoskeleton
Adherens Junctions
Glycoproteins
Desmoplakins
1986
56 Citations (Scopus)
Desmogleins
Immunosorbent Techniques
Species Specificity
Desmosomes
Antibody Specificity
63 Citations (Scopus)
Desmogleins
Desmosomes
Microinjections
Epidermis
Fluorescent Antibody Technique