• 1806 Citations
  • 15 h-Index
20032019
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Fingerprint Dive into the research topics where Pascale G Charest is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

Dictyostelium Medicine & Life Sciences
Chemotactic Factors Medicine & Life Sciences
Cell Movement Medicine & Life Sciences
Arrestin Medicine & Life Sciences
Chemotaxis Medicine & Life Sciences
Energy Transfer Medicine & Life Sciences
G-Protein-Coupled Receptors Medicine & Life Sciences
Actins Medicine & Life Sciences

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Research Output 2003 2019

  • 1806 Citations
  • 15 h-Index
  • 21 Article
  • 1 Chapter

Caffeine inhibits PI3K and mTORC2 in Dictyostelium and differentially affects multiple other cAMP chemoattractant signaling effectors

Tariqul Islam, A. F. M., Scavello, M., Lotfi, P., Daniel, D., Haldeman, P. & Charest, P. G., Jan 1 2019, In : Molecular and Cellular Biochemistry.

Research output: Contribution to journalArticle

Phosphatidylinositol 3-Kinase
Dictyostelium
Chemotactic Factors
Caffeine
TOR complex 2
1 Citation (Scopus)

The cAMP-induced G protein subunits dissociation monitored in live Dictyostelium cells by BRET reveals two activation rates, a negative effect of caffeine and potential role of microtubules

Tariqul Islam, A. F. M., Yue, H., Scavello, M., Haldeman, P., Rappel, W. J. & Charest, P. G., Aug 1 2018, In : Cellular Signalling. 48, p. 25-37 13 p.

Research output: Contribution to journalArticle

Dictyostelium
Energy Transfer
Protein Subunits
Caffeine
GTP-Binding Proteins
6 Citations (Scopus)

Protein kinase A regulates the Ras, Rap1 and TORC2 pathways in response to the chemoattractant cAMP in Dictyostelium

Scavello, M., Petlick, A. R., Ramesh, R., Thompson, V. F., Lotfi, P. & Charest, P. G., May 1 2017, In : Journal of Cell Science. 130, 9, p. 1545-1558 14 p.

Research output: Contribution to journalArticle

Dictyostelium
Chemotactic Factors
Cyclic AMP-Dependent Protein Kinases
Signal Transduction
Chemotaxis
1 Citation (Scopus)

Studying chemoattractant signal transduction dynamics in Dictyostelium by BRET

Islam, A. F. M. T., Stepanski, B. M. & Charest, P. G., 2016, Methods in Molecular Biology. Humana Press Inc., Vol. 1407. p. 63-77 15 p. (Methods in Molecular Biology; vol. 1407).

Research output: Chapter in Book/Report/Conference proceedingChapter

Dictyostelium
Energy Transfer
Chemotactic Factors
Signal Transduction
Amoeba
20 Citations (Scopus)

The small GTPases Ras and Rap1 bind to and control TORC2 activity

Khanna, A., Lotfi, P., Chavan, A. J., Montaño, N. M., Bolourani, P., Weeks, G., Shen, Z., Briggs, S. P., Pots, H., Van Haastert, P. J. M., Kortholt, A. & Charest, P. G., May 13 2016, In : Scientific Reports. 6, 25823.

Research output: Contribution to journalArticle

Monomeric GTP-Binding Proteins
Dictyostelium
Cell Movement
ras Proteins
TOR complex 2