• 1428 Citations
  • 22 h-Index
1991 …2017
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Research Output 1991 2017

  • 1428 Citations
  • 22 h-Index
  • 44 Article
4 Citations (Scopus)

Action of RecBCD enzyme on holliday structures made by RecA

Müller, B., Boehmer, P. E., Emmerson, P. T. & West, S. C., Oct 5 1991, In : Journal of Biological Chemistry. 266, 28, p. 19028-19033 6 p.

Research output: Contribution to journalArticle

Exodeoxyribonuclease V
Cruciform DNA
Rec A Recombinases
Genetic Recombination
Escherichia coli Proteins
28 Citations (Scopus)

Activation of the herpes simplex virus type-1 origin-binding protein (UL9) by heat shock proteins

Le Gac, N. T. & Boehmer, P. E., Feb 15 2002, In : Journal of Biological Chemistry. 277, 7, p. 5660-5666 7 p.

Research output: Contribution to journalArticle

Human Herpesvirus 1
Heat-Shock Proteins
Chemical activation
DNA Replication
Protein Refolding
21 Citations (Scopus)

Association between the herpes simplex virus-1 DNA polymerase and uracil DNA glycosylase

Bogani, F., Corredeira, I., Fernandez, V., Sattler, U., Rutvisuttinunt, W., Defais, M. & Boehmer, P. E., Sep 3 2010, In : Journal of Biological Chemistry. 285, 36, p. 27664-27672 9 p.

Research output: Contribution to journalArticle

Uracil-DNA Glycosidase
Human Herpesvirus 1
DNA-Directed DNA Polymerase
Viruses
DNA Repair
56 Citations (Scopus)

Association of origin binding protein and single strand DNA-binding protein, ICP8, during herpes simplex virus type 1 DNA replication in vivo

Boehmer, P. E., Craigie, M. C., Stow, N. D. & Lehman, I. R., Nov 18 1994, In : Journal of Biological Chemistry. 269, 46, p. 29329-29334 6 p.

Research output: Contribution to journalArticle

DNA-Binding Proteins
Human Herpesvirus 1
DNA Replication
Viruses
Carrier Proteins
7 Citations (Scopus)

Cysteine 111 affects coupling of single-stranded DNA binding to ATP hydrolysis in the herpes simplex virus type-1 origin-binding protein

Sampson, D. A., Arana, M. E. & Boehmer, P. E., Jan 28 2000, In : Journal of Biological Chemistry. 275, 4, p. 2931-2937 7 p.

Research output: Contribution to journalArticle

Single-Stranded DNA
Human Herpesvirus 1
Viruses
DNA Helicases
Cysteine
24 Citations (Scopus)

Effect of manganese on in vitro replication of damaged DNA catalyzed by the herpes simplex virus type-1 DNA polymerase

Villani, G., Le Gac, N. T., Wasungu, L., Burnouf, D., Fuchs, R. P. & Boehmer, P. E., Aug 1 2002, In : Nucleic Acids Research. 30, 15, p. 3323-3332 10 p.

Research output: Contribution to journalArticle

Human Herpesvirus 1
DNA-Directed DNA Polymerase
Manganese
DNA Replication
Guanine
17 Citations (Scopus)
DNA Adducts
Human Herpesvirus 1
DNA Replication
Viruses
Antineoplastic Agents
13 Citations (Scopus)

Effects of a single intrastrand d(GpG) platinum adduct on the strand separating activity of the Escherichia coli proteins RecB and RecA

Villani, G., Cazaux, C., Pillaire, M. J. & Boehmer, P. E., Oct 25 1993, In : FEBS Letters. 333, 1-2, p. 89-95 7 p.

Research output: Contribution to journalArticle

Escherichia coli Proteins
Platinum
Rec A Recombinases
Adenosine Triphosphatases
DNA
27 Citations (Scopus)

Equilibrium binding of single-stranded DNA with herpes simplex virus type I-coded single-stranded DNA-binding protein, ICP8

Gourves, A. S., Tanguy Le Gac, N., Villani, G., Boehmer, P. E. & Johnson, N. P., Apr 14 2000, In : Journal of Biological Chemistry. 275, 15, p. 10864-10869 6 p.

Research output: Contribution to journalArticle

Single-Stranded DNA
DNA-Binding Proteins
Simplexvirus
Viruses
Recombinases

Escherichia coli RecA promotes strand invasion with cisplatin-damaged DNA

Nimonkar, A. V., Le Gac, N. T., Villani, G. & Boehmer, P. E., May 2006, In : Biochimie. 88, 5, p. 535-542 8 p.

Research output: Contribution to journalArticle

Cisplatin
DNA
Oligonucleotides
Escherichia coli
Recombinases
30 Citations (Scopus)

Escherichia coli RecBCD enzyme: inducible overproduction and reconstitution of the ATP-dependent deoxyribonuclease from purified subunits

Boehmer, P. E. & Emmerson, P. T., Jun 15 1991, In : Gene. 102, 1, p. 1-6 6 p.

Research output: Contribution to journalArticle

Exodeoxyribonuclease V
Deoxyribonucleases
Protein Subunits
Adenosine Triphosphate
Escherichia coli
10 Citations (Scopus)
Human Herpesvirus 1
Simplexvirus DNA polymerase
4 Citations (Scopus)

Guanine α-carboxy nucleoside phosphonate (G-α-CNP) shows a different inhibitory kinetic profile against the DNA polymerases of human immunodeficiency virus (HIV) and herpes viruses

Balzarini, J., Menni, M., Das, K., van Berckelaer, L., Ford, A., Maguire, N. M., Liekens, S., Boehmer, P. E., Arnold, E., Götte, M. & Maguire, A. R., Jul 15 2017, In : Biochemical Pharmacology. 136, p. 51-61 11 p.

Research output: Contribution to journalArticle

Organophosphonates
Guanine
DNA-Directed DNA Polymerase
Viruses
Nucleosides
246 Citations (Scopus)

Herpes simplex virus DNA replication

Boehmer, P. E. & Lehman, I. R., 1997, In : Annual Review of Biochemistry. 66, p. 347-384 38 p.

Research output: Contribution to journalArticle

Human Herpesvirus 1
Simplexvirus
Virus Replication
DNA Replication
Viruses
11 Citations (Scopus)

Herpes Simplex Virus Type-1: A Model for Genome Transactions

Boehmer, P. E. & Villani, G., 2003, In : Progress in Nucleic Acid Research and Molecular Biology. 75, p. 139-171 33 p.

Research output: Contribution to journalArticle

Human Herpesvirus 1
Genome
DNA Replication
Homologous Recombination
DNA Helicases
69 Citations (Scopus)

Herpes simplex virus type 1 ICP8: Helix-destabilizing properties

Boehmer, P. E. & Lehman, I. R., Feb 1993, In : Journal of Virology. 67, 2, p. 711-715 5 p.

Research output: Contribution to journalArticle

Human herpesvirus 1
Human Herpesvirus 1
DNA replication
DNA Replication
single-stranded DNA
16 Citations (Scopus)
DNA Primase
DNA Helicases
Viral DNA
DNA-Binding Proteins
Human Herpesvirus 1
56 Citations (Scopus)

Herpes virus replication

Boehmer, P. E. & Nimonkar, A. V., Jan 1 2003, In : IUBMB Life. 55, 1, p. 13-22 10 p.

Research output: Contribution to journalArticle

Herpesviridae
Virus Replication
Viruses
Life cycle
Animals
3 Citations (Scopus)

Identification of two novel functional p53 responsive elements in the herpes simplex virus-1 genome

Hsieh, J-C., Kuta, R., Armour, C. R. & Boehmer, P. E., 2014, In : Virology. 460-461, 1, p. 45-54 10 p.

Research output: Contribution to journalArticle

Human Herpesvirus 1
Genome
Replication Origin
Trans-Activators
Viral Genes
22 Citations (Scopus)

Inhibition of a DNA-helicase by peptide nucleic acids

Bastide, L., Boehmer, P. E., Villani, G. & Lebleu, B., Jan 15 1999, In : Nucleic Acids Research. 27, 2, p. 551-554 4 p.

Research output: Contribution to journalArticle

Peptide Nucleic Acids
DNA Helicases
Herpes Simplex
Proteins
DNA-Directed RNA Polymerases

Inhibition of DNA transcription elongation and unwinding by bis-PNA

Bastide, L., Villani, G., Nielsen, P., Boehmer, P. E. & Lebleu, B., 1999, In : Nucleosides and Nucleotides. 18, 6-7, p. 1669-1671 3 p.

Research output: Contribution to journalArticle

DNA Helicases
DNA-Directed RNA Polymerases
Transcription
Elongation
DNA
32 Citations (Scopus)
DNA Primase
DNA Helicases
DNA-Binding Proteins
Human Herpesvirus 1
Viruses
6 Citations (Scopus)
DNA-Binding Proteins
Human Herpesvirus 1
Freezing
Melting point
Assays
17 Citations (Scopus)

Modulation of the Herpes Simplex Virus Type-1 UL9 DNA Helicase by Its Cognate Single-strand DNA-binding Protein, ICP8

Arana, M. E., Haq, B., Le Gac, N. T. & Boehmer, P. E., Mar 2 2001, In : Journal of Biological Chemistry. 276, 9, p. 6840-6845 6 p.

Research output: Contribution to journalArticle

DNA Helicases
DNA-Binding Proteins
Human Herpesvirus 1
Viruses
Modulation
14 Citations (Scopus)

On the mechanism of strand assimilation by the herpes simplex virus type-1 single-strand DNA-binding protein (ICP8)

Nimonkar, A. V. & Boehmer, P. E., Sep 15 2003, In : Nucleic Acids Research. 31, 18, p. 5275-5281 7 p.

Research output: Contribution to journalArticle

DNA-Binding Proteins
Human Herpesvirus 1
DNA
Recombinases
Nucleoproteins
7 Citations (Scopus)

On the role of proofreading exonuclease in bypass of a 1,2 d(GpG) cisplatin adduct by the herpes simplex virus-1 DNA polymerase

Arana, M. E., Song, L., Le Gac, N. T., Parris, D. S., Villani, G. & Boehmer, P. E., Jun 3 2004, In : DNA Repair. 3, 6, p. 659-669 11 p.

Research output: Contribution to journalArticle

Exonucleases
Human Herpesvirus 1
DNA-Directed DNA Polymerase
Viruses
Enzymes
8 Citations (Scopus)
Oligodeoxyribonucleotides
DNA-Binding Proteins
Human Herpesvirus 1
Viruses
Labeling
88 Citations (Scopus)
DNA-Binding Proteins
Human Herpesvirus 1
Carrier Proteins
Immobilized Proteins
Proteins
Human herpesvirus 1
DNA-binding proteins
DNA-Binding Proteins
Human Herpesvirus 1
Viruses
38 Citations (Scopus)

Reconstitution of recombination-dependent DNA synthesis in herpes simplex virus 1

Nimonkar, A. V. & Boehmer, P. E., Sep 2 2003, In : Proceedings of the National Academy of Sciences of the United States of America. 100, 18, p. 10201-10206 6 p.

Research output: Contribution to journalArticle

Human Herpesvirus 1
Genetic Recombination
Type I DNA Topoisomerase
Double-Stranded DNA Breaks
DNA
36 Citations (Scopus)

Reconstitution of the activities of the RecBCD holoenzyme of Escherichia coli from the purified subunits

Masterson, C., Boehmer, P. E., McDonald, F., Chaudhuri, S., Hickson, I. D. & Emmerson, P. T., Jul 5 1992, In : Journal of Biological Chemistry. 267, 19, p. 13564-13572 9 p.

Research output: Contribution to journalArticle

Holoenzymes
Escherichia coli
4 alpha-glucanotransferase
Exonucleases
Molecular mass
18 Citations (Scopus)

Reconstitution of uracil DNA glcosylase-initiated base excision repair in herpes simplex virus-1

Bogani, F., Chua, C. N. & Boehmer, P. E., Jun 19 2009, In : Journal of Biological Chemistry. 284, 25, p. 16784-16790 7 p.

Research output: Contribution to journalArticle

Uracil
Human Herpesvirus 1
Viruses
DNA Repair
Repair
130 Citations (Scopus)

Replication of herpes simplex virus DNA

Lehman, I. R. & Boehmer, P. E., Oct 1 1999, In : Journal of Biological Chemistry. 274, 40, p. 28059-28062 4 p.

Research output: Contribution to journalArticle

Simplexvirus
DNA
11 Citations (Scopus)
DNA-Binding Proteins
Human Herpesvirus 1
RNA
Viral Gene Expression Regulation
Plasmids
5 Citations (Scopus)

Role of protein-protein interactions during herpes simplex virus type I recombination-dependent replication

Nimonkar, A. V. & Boehmer, P. E., May 21 2004, In : Journal of Biological Chemistry. 279, 21, p. 21957-21965 9 p.

Research output: Contribution to journalArticle

Simplexvirus
Viruses
Genetic Recombination
DNA
Human Herpesvirus 1
62 Citations (Scopus)

The herpes simplex virus type-1 origin binding protein: DNA helicase activity

Boehmer, P. E., Dodson, M. S. & Lehman, I. R., Jan 15 1993, In : Journal of Biological Chemistry. 268, 2, p. 1220-1225 6 p.

Research output: Contribution to journalArticle

DNA Helicases
Human Herpesvirus 1
Viruses
Carrier Proteins
DNA
45 Citations (Scopus)

The herpes simplex virus type 1 origin-binding protein carries out origin specific DNA unwinding and forms unwound stem-loop structures

Makhov, A. M., Boehmer, P. E., Lehman, I. R. & Griffith, J. D., Apr 1 1996, In : EMBO Journal. 15, 7, p. 1742-1750 9 p.

Research output: Contribution to journalArticle

Human Herpesvirus 1
Viruses
Carrier Proteins
DNA
Proteins
35 Citations (Scopus)
DNA Helicases
DNA-Binding Proteins
Human Herpesvirus 1
Viruses
DNA
33 Citations (Scopus)

The herpes simplex virus type-1 single-strand DNA-binding protein (ICP8) promotes strand invasion

Nimonkar, A. V. & Boehmer, P. E., Mar 14 2003, In : Journal of Biological Chemistry. 278, 11, p. 9678-9682 5 p.

Research output: Contribution to journalArticle

DNA-Binding Proteins
Human Herpesvirus 1
Viruses
Plasmids
Viral Structures
33 Citations (Scopus)

The RecB protein of Escherichia coli translocates along single-stranded DNA in the 3' to 5' direction: A proposed ratchet mechanism

Phillips, R. J., Hickleton, D. C., Boehmer, P. E. & Emmerson, P. T., 1997, In : MGG Molecular & General Genetics. 254, 3, p. 319-329 11 p.

Research output: Contribution to journalArticle

Escherichia coli Proteins
Single-Stranded DNA
Adenosine Triphosphate
Proteins
Oligonucleotides
49 Citations (Scopus)

The RecB subunit of the Escherichia coli RecBCD enzyme couples ATP hydrolysis to DNA unwinding

Boehmer, P. E. & Emmerson, P. T., Mar 5 1992, In : Journal of Biological Chemistry. 267, 7, p. 4981-4987 7 p.

Research output: Contribution to journalArticle

Exodeoxyribonuclease V
Escherichia coli
Hydrolysis
Adenosine Triphosphate
DNA
13 Citations (Scopus)
Human Herpesvirus 1
DNA-Directed DNA Polymerase
DNA Repair
Lyases
Schiff Bases
47 Citations (Scopus)
DNA Primase
DNA Helicases
DNA-Binding Proteins
Human Herpesvirus 1
Viruses
37 Citations (Scopus)

Visualization of the unwinding of long DNA chains by the herpes simplex virus type 1 UL9 protein and ICP8

Makhov, A. M., Boehmer, P. E., Lehman, I. R. & Griffith, J. D., May 24 1996, In : Journal of Molecular Biology. 258, 5, p. 789-799 11 p.

Research output: Contribution to journalArticle

Human Herpesvirus 1
DNA
Proteins
Negative Staining
Carrier Proteins