Raymond B Nagle

  • 11533 Citations
  • 58 h-Index
1968 …2020

Research output per year

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Research Output

2020

Centrosome loss results in an unstable genome and malignant prostate tumors

Wang, M., Nagle, R. B., Knudsen, B. S., Cress, A. E. & Rogers, G. C., Jan 9 2020, In : Oncogene. 39, 2, p. 399-413 15 p.

Research output: Contribution to journalArticle

2 Scopus citations
2019

A method of quantifying centrosomes at the single-cell level in human normal and cancer tissue

Wang, M., Knudsen, B. S., Nagle, R. B., Rogers, G. C. & Cress, A. E., 2019, In : Molecular biology of the cell. 30, 7, p. 811-819 9 p.

Research output: Contribution to journalArticle

Open Access
4 Scopus citations

Gene editing of α6 integrin inhibits muscle invasive networks and increases cell-cell biophysical properties in prostate cancer

Rubenstein, C. S., Gard, J. M. C., Wang, M., McGrath, J. E., Ingabire, N., Hinton, J. P., Marr, K. D., Simpson, S. J., Nagle, R. B., Miranti, C. K., Warfel, N. A., Garcia, J. G. N., Arif-Tiwari, H. & Cress, A. E., Sep 15 2019, In : Cancer Research. 79, 18, p. 4703-4714 12 p.

Research output: Contribution to journalArticle

Open Access
3 Scopus citations

Kallikrein 6 protease advances colon tumorigenesis via induction of the high mobility group A2 protein

Chen, H., Sells, E., Pandey, R., Abril, E. R., Hsu, C. H., Krouse, R. S., Nagle, R. B., Pampalakis, G., Sotiropoulou, G. & Ignatenko, N. A., 2019, In : Oncotarget. 10, 58, p. 6062-6078 17 p.

Research output: Contribution to journalArticle

Open Access
3 Scopus citations

The Tumor Microenvironments of Lethal Prostate Cancer

Harryman, W. L., Warfel, N. A., Nagle, R. B. & Cress, A. E., Jan 1 2019, Advances in Experimental Medicine and Biology. Springer, p. 149-170 22 p. (Advances in Experimental Medicine and Biology; vol. 1210).

Research output: Chapter in Book/Report/Conference proceedingChapter

2018

A new species of Euchaetes Harris from southern arizona (Erebidae, arctiinae)

Nagle, R. B. & Christian Schmidt, B., 2018, In : ZooKeys. 2018, 788, p. 69-77 9 p.

Research output: Contribution to journalArticle

1 Scopus citations

Bioactivity and prostate tissue distribution of metformin in a preprostatectomy prostate cancer cohort

Nguyen, M. M., Martinez, J. A., Hsu, C. H., Sokoloff, M., Krouse, R. S., Gibson, B. A., Nagle, R. B., Parnes, H. L., Cordova, C. & Chow, H. H. S., Nov 1 2018, In : European Journal of Cancer Prevention. 27, 6, p. 557-562 6 p.

Research output: Contribution to journalArticle

4 Scopus citations

Does mutated K-RAS oncogene attenuate the effect of sulindac in colon cancer chemoprevention?

Rice, P. F. S., Ehrichs, K. G., Jones, M. S., Chen, H. D. R., Hsu, C-H., Abril, E. R., Nagle, R. B., Besselsen, D. G., Barton, J. K. & Ignatenko, N., Jan 1 2018, In : Cancer Prevention Research. 11, 1, p. 16-26 11 p.

Research output: Contribution to journalArticle

2 Scopus citations

Novel regulation of integrin trafficking by rab11-FIP5 in aggressive prostate cancer

Das, L., Gard, J. M. C., Prekeris, R., Nagle, R. B., Morrissey, C., Knudsen, B. S., Miranti, C. K. & Cress, A. E., Aug 2018, In : Molecular Cancer Research. 16, 8, p. 1319-1331 13 p.

Research output: Contribution to journalArticle

4 Scopus citations
2017

A basal cell defect promotes budding of prostatic intraepithelial neoplasia

Wang, M., Nagle, R. B., Knudsen, B. S., Rogers, G. C. & Cress, A. E., 2017, In : Journal of Cell Science. 130, 1, p. 104-110 7 p.

Research output: Contribution to journalArticle

8 Scopus citations

Characterization of Laminin Binding Integrin Internalization in Prostate Cancer Cells

Das, L., Anderson, T. A., Gard, J. M. C., Sroka, I. C., Strautman, S. R., Nagle, R. B., Morrissey, C., Knudsen, B. S. & Cress, A. E., May 1 2017, In : Journal of Cellular Biochemistry. 118, 5, p. 1038-1049 12 p.

Research output: Contribution to journalArticle

13 Scopus citations

Inhibition of ciliogenesis promotes Hedgehog signaling, tumorigenesis, and metastasis in breast cancer

Hassounah, N. B., Nunez, M., Fordyce, C., Roe, D., Nagle, R., Bunch, T. & McDermott, K. M., Oct 1 2017, In : Molecular Cancer Research. 15, 10, p. 1421-1430 10 p.

Research output: Contribution to journalArticle

15 Scopus citations
2016

A pilot study exploring the molecular architecture of the tumor microenvironment in human prostate cancer using laser capture microdissection and reverse phase protein microarray

Pin, E., Stratton, S., Belluco, C., Liotta, L., Nagle, R., Hodge, K. A., Deng, J., Dong, T., Baldelli, E., Petricoin, E. & Pierobon, M., Dec 1 2016, In : Molecular Oncology. 10, 10, p. 1585 1 p.

Research output: Contribution to journalArticle

12 Scopus citations

Laminin-binding integrin gene copy number alterations in distinct epithelial-type cancers

Harryman, W. L., Pond, E., Singh, P. ., Little, A. S., Eschbacher, J. M., Nagle, R. B. & Cress, A. E., 2016, In : American Journal of Translational Research. 8, 2, p. 940-954 15 p.

Research output: Contribution to journalArticle

6 Scopus citations

Schwann Cells Increase Prostate and Pancreatic Tumor Cell Invasion Using Laminin Binding A6 Integrin

Sroka, I. C., Chopra, H., Das, L., Gard, J. M. C., Nagle, R. B. & Cress, A. E., Feb 1 2016, In : Journal of Cellular Biochemistry. 117, 2, p. 491-499 9 p.

Research output: Contribution to journalArticle

15 Scopus citations

The Cohesive Metastasis Phenotype in Human Prostate Cancer

Harryman, W. L., Hinton, J. P., Rubenstein, C. P., Singh, P., Nagle, R. B., Parker, S. J., Knudsen, B. S. & Cress, A. E., Dec 1 2016, In : Biochimica et Biophysica Acta - Reviews on Cancer. 1866, 2, p. 221-231 11 p.

Research output: Contribution to journalReview article

20 Scopus citations
2015

Characterization of a novel radiation-induced sarcoma cell line

Lang, J., Zhu, W., Nokes, B., Sheth, G., Novak, P., Fuchs, L., Watts, G., Futscher, B., Mineyev, N., Ring, A., Lebeau, L., Nagle, R. & Cranmer, L., May 1 2015, In : Journal of Surgical Oncology. 111, 6, p. 669-682 14 p.

Research output: Contribution to journalArticle

1 Scopus citations

Combined micro CT and histopathology for evaluation of skeletal metastasis in live animals

Geffre, C. P., Pond, E., Pond, G. D., Sroka, I. C., Gard, J. M., Skovan, B. A., Meek, W. E., Landowski, T. H., Nagle, R. B. & Cress, A. E., 2015, In : American Journal of Translational Research. 7, 2, p. 348-355 8 p.

Research output: Contribution to journalArticle

6 Scopus citations

Determination of optimum formalin fixation duration for prostate needle biopsies for immunohistochemistry and quantum dot FISH analysis

Sathyanarayana, U. G., Birch, C., Nagle, R. B., Tomlins, S. A., Palanisamy, N., Zhang, W., Hubbard, A., Brunhoeber, P., Wang, Y. & Tang, L., May 26 2015, In : Applied Immunohistochemistry and Molecular Morphology. 23, 5, p. 364-373 10 p.

Research output: Contribution to journalArticle

4 Scopus citations

Multi-modal contrast of tissue anatomy enables correlative biomarker imaging

Garsha, K., Ventura, F., Pestano, G., Otter, M., Nagy, D., Nagle, R. B., Roberts, E. & Barnes, M., Jan 1 2015, Multimodal Biomedical Imaging X. Azar, F. S. & Intes, X. (eds.). SPIE, 931608. (Progress in Biomedical Optics and Imaging - Proceedings of SPIE; vol. 9316).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

1 Scopus citations
2014

Intracellular modifiers of integrin alpha 6p production in aggressive prostate and breast cancer cell lines

Kacsinta, A. D., Rubenstein, C. S., Sroka, I. C., Pawar, S., Gard, J. M., Nagle, R. B. & Cress, A. E., Nov 14 2014, In : Biochemical and Biophysical Research Communications. 454, 2, p. 335-340 6 p.

Research output: Contribution to journalArticle

11 Scopus citations

Loss of primary cilia occurs early in breast cancer development

Menzl, I., Lebeau, L., Pandey, R., Hassounah, N. B., Li, F. W., Nagle, R., Weihs, K. & McDermott, K. M., 2014, In : Cilia. 3, 1, 7.

Research output: Contribution to journalArticle

61 Scopus citations

Nanoparticle delivery of an akt/pdk1 inhibitor improves the therapeutic effect in pancreatic cancer

Lucero-Acuña, A., Jeffery, J. J., Abril, E. R., Nagle, R. B., Guzman, R., Pagel, M. D. & Meuillet, E. J., 2014, In : International journal of nanomedicine. 9, 1, p. 5653-5665 13 p.

Research output: Contribution to journalArticle

11 Scopus citations

Targeting integrin α6 stimulates curative-type bone metastasis lesions in a xenograft model

Landowski, T. H., Gard, J., Pond, E., Pond, G. D., Nagle, R. B., Geffre, C. P. & Cress, A. E., Jun 2014, In : Molecular Cancer Therapeutics. 13, 6, p. 1558-1566 9 p.

Research output: Contribution to journalArticle

22 Scopus citations
2013

ERG overexpression and PTEN status predict capsular penetration in prostate carcinoma

Nagle, R. B., Algotar, A. M., Cortez, C. C., Smith, K., Jones, C., Sathyanarayana, U. G., Yun, S., Riley, J., Nagy, D., Dittamore, R., Dalkin, B., Brosh, L. & Pestano, G., Aug 2013, In : Prostate. 73, 11, p. 1233-1240 8 p.

Research output: Contribution to journalArticle

14 Scopus citations

Human breast tissue disposition and bioactivity of limonene in women with early-stage breast cancer

Miller, J. A., Lang, J. E., Ley, M., Nagle, R., Hsu, C. H., Thompson, P. A., Cordova, C., Waer, A. & Chow, H. H. S., Jun 2013, In : Cancer Prevention Research. 6, 6, p. 577-584 8 p.

Research output: Contribution to journalArticle

42 Scopus citations

Immunohistochemical quantification of the vitamin B12 transport protein (TCII), cell surface receptor (TCII-R) and Ki-67 in human tumor xenografts

Sysel, A. M., Valli, V. E., Nagle, R. B. & Bauer, J. A., Oct 2013, In : Anticancer research. 33, 10, p. 4203-4212 10 p.

Research output: Contribution to journalArticle

23 Scopus citations

Phase 3 clinical trial investigating the effect of selenium supplementation in men at high-risk for prostate cancer

Algotar, A. M., Stratton, M. S., Ahmann, F. R., Ranger-Moore, J., Nagle, R. B., Thompson, P. A., Slate, E., Hsu, C. H., Dalkin, B. L., Sindhwani, P., Holmes, M. A., Tuckey, J. A., Graham, D. L., Parnes, H. L., Clark, L. C. & Stratton, S. P., Feb 15 2013, In : Prostate. 73, 3, p. 328-335 8 p.

Research output: Contribution to journalArticle

58 Scopus citations

Primary Cilia Are Lost in Preinvasive and Invasive Prostate Cancer

Hassounah, N. B., Nagle, R., Saboda, K., Roe, D. J., Dalkin, B. L. & McDermott, K. M., Jul 2 2013, In : PloS one. 8, 7, e68521.

Research output: Contribution to journalArticle

63 Scopus citations
2012

Differences in characteristics of men with localised prostate cancer who demonstrate low, intermediate or high prostate-specific antigen velocity

Algotar, A. M., Thompson, P. A., Ranger-Moore, J., Stratton, M. S., Hsu, C. H., Ahmann, F. R., Nagle, R. B. & Stratton, S. P., Apr 2012, In : Internal Medicine Journal. 42, 4, p. 374-380 7 p.

Research output: Contribution to journalArticle

1 Scopus citations
85 Scopus citations

Randomized, double-blind, placebo-controlled trial of sulindac in individuals at risk for melanoma: Evaluation of potential chemopreventive activity

Curiel-Lewandrowski, C., Swetter, S. M., Einspahr, J. G., Hsu, C. H., Nagle, R., Sagerman, P., Tangrea, J., Parnes, H., Alberts, D. S. & Chow, H. H., Dec 1 2012, In : Cancer. 118, 23, p. 5848-5856 9 p.

Research output: Contribution to journalArticle

11 Scopus citations
2011

Association of long-term administration of the survivin mRNA-targeted antisense oligonucleotide LY2181308 with reversible kidney injury in a patient with metastatic melanoma

Herrington, W. G., Talbot, D. C., Lahn, M. M., Brandt, J. T., Callies, S., Nagle, R., Winearls, C. G. & Roberts, I. S. D., Feb 1 2011, In : American Journal of Kidney Diseases. 57, 2, p. 300-303 4 p.

Research output: Contribution to journalArticle

25 Scopus citations

Association of Obesity and Smoking With PSA and PSA Velocity in Men With Prostate Cancer

Algotar, A. M., Stratton, S. P., Ranger-Moore, J., Stratton, M. S., Hsu, C. H., Ahmann, F. R., Nagle, R. B. & Thompson, P. A., May 2011, In : American journal of men's health. 5, 3, p. 272-278 7 p.

Research output: Contribution to journalArticle

8 Scopus citations

Automated brightfield dual-color in situ hybridization for detection of mouse double minute 2 gene amplification in sarcomas

Zhang, W., McElhinny, A., Nielsen, A., Wang, M., Miller, M., Singh, S., Rueger, R., Rubin, B. P., Wang, Z., Tubbs, R. R., Nagle, R. B., Roche, P., Wu, P. & Pestic-Dragovich, L., Jan 1 2011, In : Applied Immunohistochemistry and Molecular Morphology. 19, 1, p. 54-61 8 p.

Research output: Contribution to journalArticle

13 Scopus citations

CD44 Promotes Epithelial Mammary Gland Development and Exhibits Altered Localization during Cancer Progression

Louderbough, J. M. V., Brown, J. A., Nagle, R. B. & Schroeder, J. A., Aug 2011, In : Genes and Cancer. 2, 8, p. 771-781 11 p.

Research output: Contribution to journalArticle

18 Scopus citations

Dose-dependent effects of selenized yeast on total selenium levels in prostatic tissue of men with prostate cancer

Algotar, A. M., Stratton, M. S., Xu, M. J., Dalkin, B. L., Nagle, R. B., Hsu, C. H., Ahmann, F. R., Clark, L. C. & Stratton, S. P., Jan 2011, In : Nutrition and cancer. 63, 1, p. 1-5 5 p.

Research output: Contribution to journalArticle

9 Scopus citations

ERK crosstalks with 4EBP1 to activate cyclin D1 translation during quinol-thioether-induced tuberous sclerosis renal cell carcinoma

Cohen, J. D., Gard, J. M. C., Nagle, R. B., Dietrich, J. D., Monks, T. J. & Lau, S. S., Nov 2011, In : Toxicological Sciences. 124, 1, p. 75-87 13 p., kfr203.

Research output: Contribution to journalArticle

16 Scopus citations
2010

Effect of aspirin, other NSAIDs, and statins on PSA and PSA velocity

Algotar, A. M., Thompson, P. A., Ranger-Moore, J., Stratton, M. S., Hsu, C. H., Ahmann, F. R., Nagle, R. B. & Stratton, S. P., Jun 1 2010, In : Prostate. 70, 8, p. 883-888 6 p.

Research output: Contribution to journalArticle

24 Scopus citations

Overexpression of tumor vascular endothelial growth factor A may portend an increased likelihood of progression in a phase II trial of bevacizumab and erlotinib in resistant ovarian cancer

Chambers, S. K., Clouser, M. C., Baker, A. F., Roe, D. J., Cui, H., Brewer, M. A., Hatch, K. D., Gordon, M. S., Janicek, M. F., Isaacs, J. D., Gordon, A. N., Nagle, R. B., Wright, H. M., Cohen, J. L. & Alberts, D. S., Nov 1 2010, In : Clinical Cancer Research. 16, 21, p. 5320-5328 9 p.

Research output: Contribution to journalArticle

47 Scopus citations

Silver in situ hybridization (SISH) for determination of HER2 gene status in breast carcinoma: Comparison with fish and assessment of interobserver reproducibility

Papouchado, B. G., Myles, J., Lloyd, R. V., Stoler, M., Oliveira, A. M., Downs-Kelly, E., Morey, A., Bilous, M., Nagle, R., Prescott, N., Wang, L., Dragovich, L., McElhinny, A., Garcia, C. F., Ranger-Moore, J., Free, H., Powell, W., Loftus, M., Pettay, J., Gaire, F. & 5 others, Roberts, C., Dietel, M., Roche, P., Grogan, T. & Tubbs, R., Jun 2010, In : American Journal of Surgical Pathology. 34, 6, p. 767-776 10 p.

Research output: Contribution to journalArticle

73 Scopus citations

The laminin binding integrin α6β1 in prostate cancer perineural invasion

Sroka, I. C., Anderson, T. A., Mcdaniel, K. M., Nagle, R. B., Gretzer, M. B. & Cress, A. E., Aug 2010, In : Journal of Cellular Physiology. 224, 2, p. 283-288 6 p.

Research output: Contribution to journalShort survey

45 Scopus citations
2009

Design and activity of a murine and humanized anti-CEACAM6 single-chain variable fragment in the treatment of pancreatic cancer

Riley, C. J., Engelhardt, K. P., Saldanha, J. W., Qi, W., Cooke, L. S., Zhu, Y., Narayan, S. T., Shakalya, K., Croce, K. D., Georgiev, I. G., Nagle, R. C., Garewal, H. D., Von Hoff, D. D. & Mahadevan, D., Mar 1 2009, In : Cancer Research. 69, 5, p. 1933-1940 8 p.

Research output: Contribution to journalArticle

31 Scopus citations

Extracellular engagement of α6 integrin inhibited urokinase-type plasminogen activator-mediated cleavage and delayed human prostate bone metastasis

Ports, M. O., Nagle, R. B., Pond, G. D. & Cress, A. E., Jun 15 2009, In : Cancer Research. 69, 12, p. 5007-5014 8 p.

Research output: Contribution to journalArticle

42 Scopus citations

Phase II study of erlotinib in patients with locally advanced or metastatic papillary histology renal cell cancer: SWOG S0317

Gordon, M. S., Hussey, M., Nagle, R. B., Lara, P. N., Mack, P. C., Dutcher, J., Samlowski, W., Clark, J. I., Quinn, D. I., Pan, C. X. & Crawford, D., Dec 1 2009, In : Journal of Clinical Oncology. 27, 34, p. 5788-5793 6 p.

Research output: Contribution to journalArticle

78 Scopus citations
2008

Cross-validation of murine UV signal transduction pathways in human skin

Einspahr, J. G., Timothy Bowden, G., Alberts, D. S., McKenzie, N., Saboda, K., Warneke, J., Salasche, S., Ranger-Moore, J., Curiel-Lewandrowski, C., Nagle, R. B., Nickoloff, B. J., Brooks, C., Dong, Z. & Stratton, S. P., Mar 2008, In : Photochemistry and Photobiology. 84, 2, p. 463-476 14 p.

Research output: Contribution to journalArticle

23 Scopus citations

Differential localization of MTI-MMP in human prostate cancer tissue: Role of IGF-IR in MTI-MMP expression

Sroka, I. C., McDaniel, K., Nagle, R. B. & Bowden, G. T., Apr 1 2008, In : Prostate. 68, 5, p. 463-476 14 p.

Research output: Contribution to journalArticle

12 Scopus citations

Quantitative, spatial resolution of the epigenetic field effect in prostate cancer

Mehrotra, J., Varde, S., Wang, H., Chiu, H., Vargo, J., Gray, K., Nagle, R. B., Neri, J. R. & Mazumder, A., Feb 1 2008, In : Prostate. 68, 2, p. 152-160 9 p.

Research output: Contribution to journalArticle

54 Scopus citations

Sympathetic nerves in the tarsal tunnel: Implications for blood flow in the diabetic foot

Blount, A. L., Peled, Z. M., Dexter, E. L., Nagle, R. B., Maloney, C. T. & Dellon, A. L., Jul 1 2008, In : Plastic and reconstructive surgery. 122, 1, p. 188-191 4 p.

Research output: Contribution to journalArticle

7 Scopus citations