Raymond B Nagle

  • 11228 Citations
  • 57 h-Index
1968 …2021
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Research Output 1968 2019

  • 11228 Citations
  • 57 h-Index
  • 271 Article
  • 3 Chapter
  • 1 Conference contribution
  • 1 Review article
21 Citations (Scopus)

90K/Mac-2 binding protein is expressed in prostate cancer and induces promatrilysin expression

Bair, E. L., Nagle, R. B., Ulmer, T. A., Laferté, S. & Bowden, G. T., Feb 15 2006, In : Prostate. 66, 3, p. 283-293 11 p.

Research output: Contribution to journalArticle

Prostatic Neoplasms
Carrier Proteins
Prostate
Cell Line
Neoplasms
5 Citations (Scopus)

A basal cell defect promotes budding of prostatic intraepithelial neoplasia

Wang, M., Nagle, R. B., Knudsen, B. S., Rogers, G. C. & Cress, A. E., 2017, In : Journal of Cell Science. 130, 1, p. 104-110 7 p.

Research output: Contribution to journalArticle

Prostatic Intraepithelial Neoplasia
Integrins
Cellular Spheroids
Genomic Instability
Keratins
21 Citations (Scopus)

Aberrant expression of fibroblast growth factor receptor-1 in prostate epithelial cells allows induction of promatrilysin expression by fibroblast growth factors

Udayakumar, T. S., Klein, R. D., Maliner, M. S., Nagle, R. B. & Bowden, G. T., Jan 15 2001, In : International Journal of Cancer. 91, 2, p. 187-192 6 p.

Research output: Contribution to journalArticle

Receptor, Fibroblast Growth Factor, Type 1
Fibroblast Growth Factors
Fibroblast Growth Factor Receptors
Prostate
Epithelial Cells
27 Citations (Scopus)
Needle Biopsy
Prostatectomy
Prostate
Biopsy
Neoplasms
23 Citations (Scopus)

A comprehensive immunotopographic map of human thymus

Wirt, D. P., Grogan, T. M., Nagle, R. B., Copeland, J. G., Richter, L. C., Rangel, C. S., Schuchardt, M., Fosse, J. & Layton, J. M., 1988, In : Journal of Histochemistry and Cytochemistry. 36, 1, p. 1-12 12 p.

Research output: Contribution to journalArticle

Thymus Gland
B-Lymphocytes
Epithelial Cells
T-Lymphocytes
Reticulum
47 Citations (Scopus)

Activation of gelatinase-tissue-inhibitors-of-metalloproteinase complexes by matrilysin

Von Bredow, D. C., Cress, A. E., Howard, E. W., Bowden, G. T. & Nagle, R. B., May 1 1998, In : Biochemical Journal. 331, 3, p. 965-972 8 p.

Research output: Contribution to journalArticle

Matrix Metalloproteinase 7
Tissue Inhibitor of Metalloproteinases
Gelatinases
Matrix Metalloproteinase Inhibitors
Chemical activation
48 Citations (Scopus)

Acute glomerulonephritis with prolonged oliguria. An analysis of 29 cases.

Leonard, C. D., Nagle, R. B., Striker, G. E., Cutler, R. E. & Scribner, B. H., Nov 1970, In : Annals of Internal Medicine. 73, 5, p. 703-711 9 p.

Research output: Contribution to journalArticle

Kidney Function Tests
Oliguria
Anuria
Streptococcal Infections
Uremia
35 Citations (Scopus)

Acute tubular necrosis in the rat kidney following sustained hypotension. Physiologic and morphologic observations

Dobyan, D. C., Nagle, R. B. & Bulger, R. E., 1977, In : Laboratory Investigation. 37, 4, p. 411-422 12 p.

Research output: Contribution to journalArticle

Rectum
Hypotension
Necrosis
Kidney
Smooth Endoplasmic Reticulum
78 Citations (Scopus)

Adhesion molecules, extracellular matrix, and proteases in prostate carcinoma

Nagle, R. B., Knox, J. D., Wolf, C., Bowden, G. T. & Cress, A. E., 1994, In : Journal of Cellular Biochemistry. 56, SUPPL. 19, p. 232-237 6 p.

Research output: Contribution to journalArticle

Matrix Metalloproteinase 7
Integrins
Extracellular Matrix
Prostate
Peptide Hydrolases
48 Citations (Scopus)

Adult-onset acid maltase deficiency: a postmortem study.

DiMauro, S., Stern, L. Z., Mehler, M., Nagle, R. B. & Payne, C., Jan 1978, In : Muscle and Nerve. 1, 1, p. 27-36 10 p.

Research output: Contribution to journalArticle

Glycogen Storage Disease Type II
alpha-Glucosidases
Skeletal Muscle
Muscles
Liver
6 Citations (Scopus)

A human xenograft model for testing early events of epithelial neoplastic invasion

Mccandless, J. R., Cress, A. E., Rabinovitz, I., Payne, C. M., Bowden, G. T., Knox, J. D. & Nagle, R. B., Feb 1997, In : International Journal of Oncology. 10, 2, p. 279-285 7 p.

Research output: Contribution to journalArticle

Heterografts
Diaphragm
SCID Mice
Neoplasms
Basement Membrane

A hypovolemic model of acute tubular necrosis in the absence of renal failure

Dobyan, D. C., Nagle, R. B., Trump, B. F. & Bulger, R. E., 1976, In : Kidney International. 10, 6, p. 556 1 p.

Research output: Contribution to journalArticle

Hypovolemia
Renal Insufficiency
Necrosis
9 Citations (Scopus)

Alteration of the structure and function of guinea pig peritoneal macrophages by a soybean oil emulsion

Strunk, R. C., Payne, C. M., Nagle, R. B. & Kunke, K., 1979, In : American Journal of Pathology. 96, 3, p. 753-770 18 p.

Research output: Contribution to journalArticle

Soybean Oil
Peritoneal Macrophages
Emulsions
Guinea Pigs
Eating
13 Citations (Scopus)

Altered surface expression and increased turnover of the α6β4 integrin in an undifferentiated carcinoma

Witkowski, C. M., Bowden, G. T., Nagle, R. B. & Cress, A. E., 2000, In : Carcinogenesis. 21, 2, p. 325-330 6 p.

Research output: Contribution to journalArticle

Integrins
Carcinoma
Keratinocytes
Papilloma
Hemidesmosomes
1 Citation (Scopus)

A method of quantifying centrosomes at the single-cell level in human normal and cancer tissue

Wang, M., Knudsen, B. S., Nagle, R. B., Rogers, G. C. & Cress, A. E., Mar 21 2019, In : Molecular biology of the cell. 30, 7, p. 811-819 9 p.

Research output: Contribution to journalArticle

Open Access
Centrosome
Neoplasms
Centrioles
Cell Size
Microscopy
2 Citations (Scopus)

Androgens block interleukin-1β-induced promatrilysin expression in prostate carcinoma cells

Stratton, M. S., Greenstein, B., Udayakumar, T. S., Nagle, R. B. & Bowden, G. T., Sep 15 2002, In : Prostate. 53, 1, p. 1-8 8 p.

Research output: Contribution to journalArticle

Interleukin-1
Androgens
Prostate
Interleukin-6
Testosterone
7 Citations (Scopus)
Intermediate Filaments
Avidin
Keratins
Formaldehyde
Epitopes
Sextants
Biopsy
Keratins
Prostate
Immunohistochemistry
50 Citations (Scopus)

A new rabbit monoclonal antibody (4B5) for the immunohistochemical (IHC) determination of the HER2 status in breast cancer: Comparison with CB11, fluorescence in situ hybridization (FISH), and interlaboratory reproducibility

Powell, W. C., Hicks, D. G., Prescott, N., Tarr, S. M., Laniauskas, S., Williams, T., Short, S., Pettay, J., Nagle, R. B., Dabbs, D. J., Scott, K. M., Brown, R. W., Grogan, T., Roche, P. C. & Tubbs, R. R., Mar 2007, In : Applied Immunohistochemistry and Molecular Morphology. 15, 1, p. 94-102 9 p.

Research output: Contribution to journalArticle

Fluorescence In Situ Hybridization
Monoclonal Antibodies
Staining and Labeling
Breast Neoplasms
Rabbits
1 Citation (Scopus)

A new species of Euchaetes Harris from southern arizona (Erebidae, arctiinae)

Nagle, R. B. & Christian Schmidt, B., Jan 1 2018, In : ZooKeys. 2018, 788, p. 69-77 9 p.

Research output: Contribution to journalArticle

Arctiinae
host plant
egg
new species
larva
47 Citations (Scopus)

Angiogenesis and neovascularization associated with extracellular matrix-modified porous implants

Kidd, K. R., Nagle, R. B. & Williams, S. K., 2002, In : Journal of Biomedical Materials Research. 59, 2, p. 366-377 12 p.

Research output: Contribution to journalArticle

Polytetrafluoroethylene
Polytetrafluoroethylenes
Rats
Tissue
Blood vessels
110 Citations (Scopus)

Anomalous cytokeratin expression in malignant melanoma: one- and two-dimensional western blot analysis and immunohistochemical survey of 100 melanomas.

Zarbo, R. J., Gown, A. M., Nagle, R. B., Visscher, D. W. & Crissman, J. D., Jul 1990, In : Modern Pathology. 3, 4, p. 494-501 8 p.

Research output: Contribution to journalArticle

Keratins
Melanoma
Western Blotting
Carcinoma
Amelanotic Melanoma
189 Citations (Scopus)

A novel tyrosine kinase switch is a mechanism of imatinib resistance in gastrointestinal stromal tumors

Mahadevan, D., Cooke, L., Riley, C., Swart, R., Simons, B., Della Croce, K., Wisner, L., Iorio, M., Shakalya, K., Garewal, H., Nagle, R. B. & Bearss, D., Jun 7 2007, In : Oncogene. 26, 27, p. 3909-3919 11 p.

Research output: Contribution to journalArticle

Gastrointestinal Stromal Tumors
Protein-Tyrosine Kinases
docetaxel
Phosphotransferases
Stromal Cells

Antibodies reactive with intermediate filament proteins: new tools for the pathologist.

Nagle, R. B., Mar 1984, In : Arizona Medicine. 41, 3, p. 177-179 3 p.

Research output: Contribution to journalArticle

Neurofilament Proteins
Intermediate Filament Proteins
Desmin
Glial Fibrillary Acidic Protein
Vimentin
14 Citations (Scopus)

An ultrastructural evaluation of the cell organelle specificity of the uranaffin reaction in two human endocrine neoplasms

Payne, C. M., Nagle, R. B., Borduin, V. F. & Kim, A., 1983, Journal of Submicroscopic Cytology. 3 ed. Vol. 15. p. 833-841 9 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Organelles
Neoplasms
Cacodylic Acid
Buffers
Islet Cell Carcinoma
6 Citations (Scopus)

An ultrastructural study of intranuclear rodlets in a malignant extracranial neuroepithelial neoplasm

Payne, C. M. & Nagle, R. B., 1983, In : Ultrastructural Pathology. 5, 1, p. 1-13 13 p.

Research output: Contribution to journalArticle

Neuroepithelial Neoplasms
neoplasms
Physiology
Neurology
Electron microscopy
9 Citations (Scopus)

A pilot study exploring the molecular architecture of the tumor microenvironment in human prostate cancer using laser capture microdissection and reverse phase protein microarray

Pin, E., Stratton, S. P., Belluco, C., Liotta, L., Nagle, R. B., Hodge, K. A., Deng, J., Dong, T., Baldelli, E., Petricoin, E. & Pierobon, M., Dec 1 2016, In : Molecular Oncology. 10, 10, p. 1234 1 p.

Research output: Contribution to journalArticle

Laser Capture Microdissection
Protein Array Analysis
Tumor Microenvironment
Prostatic Neoplasms
Epithelium
1 Citation (Scopus)

A quantitative light- and elecron-microscopic study of type IV nuclear bodies in crescentic glomerulonephritis

Graham, A. R., Payne, C. M. & Nagle, R. B., 1981, In : American Journal of Pathology. 102, 3, p. 359-366 8 p.

Research output: Contribution to journalArticle

Glomerulonephritis
Light
Electron Microscopy
Fibroblasts
Epithelial Cells

A receptor for activated C3 in the human renal glomerular capillary wall.

Gelfand, M. C., Frank, M. M., Nagle, R. B., Shin, M. & Green, I., Nov 1975, In : Proceedings of the Clinical Dialysis and Transplant Forum. 5, p. 102-105 4 p.

Research output: Contribution to journalArticle

Kidney Glomerulus
Complement C3
Fluorescence Microscopy
Fluorescent Antibody Technique
Erythrocytes
46 Citations (Scopus)

A review of intermediate filament biology and their use in pathologic diagnosis

Nagle, R. B., Jan 1994, In : Molecular Biology Reports. 19, 1, p. 3-21 19 p.

Research output: Contribution to journalArticle

Intermediate Filament Proteins
Intermediate Filaments
Immunohistochemistry
Neoplasms
18 Citations (Scopus)
Poisons
Cysteine
Toxicity
Rabbits
Kidney
23 Citations (Scopus)

Association of long-term administration of the survivin mRNA-targeted antisense oligonucleotide LY2181308 with reversible kidney injury in a patient with metastatic melanoma

Herrington, W. G., Talbot, D. C., Lahn, M. M., Brandt, J. T., Callies, S., Nagle, R. B., Winearls, C. G. & Roberts, I. S. D., Feb 2011, In : American Journal of Kidney Diseases. 57, 2, p. 300-303 4 p.

Research output: Contribution to journalArticle

Antisense Oligonucleotides
Melanoma
Kidney
Messenger RNA
Wounds and Injuries
8 Citations (Scopus)

Association of obesity and smoking with PSA and PSA velocity in men with prostate cancer.

Algotar, A. M., Stratton, S. P., Ranger-Moore, J., Stratton, M. S., Hsu, C-H., Ahmann, F. R., Nagle, R. B. & Thompson, P. A., May 2011, In : American Journal of Men's Health. 5, 3, p. 272-278 7 p.

Research output: Contribution to journalArticle

Prostate-Specific Antigen
smoking
Prostatic Neoplasms
cancer
Obesity
49 Citations (Scopus)

Aurora-A over-expression in high-grade PIN lesions and prostate cancer

Buschhorn, H. M., Klein, R. R., Chambers, S. M., Hardy, M. C., Green, S., Bearss, D. & Nagle, R. B., Sep 1 2005, In : Prostate. 64, 4, p. 341-346 6 p.

Research output: Contribution to journalArticle

Prostatic Intraepithelial Neoplasia
Prostatic Neoplasms
Prostate
Aurora Kinase A
Staining and Labeling
11 Citations (Scopus)

Automated brightfield dual-color in situ hybridization for detection of mouse double minute 2 gene amplification in sarcomas

Zhang, W., McElhinny, A., Nielsen, A., Wang, M., Miller, M., Singh, S., Rueger, R., Rubin, B. P., Wang, Z., Tubbs, R. R., Nagle, R. B., Roche, P., Wu, P. & Pestic-Dragovich, L., Jan 2011, In : Applied Immunohistochemistry and Molecular Morphology. 19, 1, p. 54-61 8 p.

Research output: Contribution to journalArticle

Gene Amplification
Sarcoma
In Situ Hybridization
Color
Chromosomes, Human, Pair 12
4 Citations (Scopus)

Bioactivity and prostate tissue distribution of metformin in a preprostatectomy prostate cancer cohort

Nguyen, M. M., Martinez, J. A., Hsu, C-H., Sokoloff, M., Krouse, R. S., Gibson, B. A., Nagle, R. B., Parnes, H. L., Cordova, C. & Chow, H-H., Jul 7 2017, (Accepted/In press) In : European Journal of Cancer Prevention.

Research output: Contribution to journalArticle

Metformin
Tissue Distribution
Prostate
Prostatic Neoplasms
Biomarkers
21 Citations (Scopus)

Biosynthesis and secretion of laminin and S-laminin by human prostate carcinoma cell lines

Rabinovitz, I., Cress, A. E. & Nagle, R. B., 1994, In : Prostate. 25, 2, p. 97-107 11 p.

Research output: Contribution to journalArticle

Laminin
Prostate
Carcinoma
Cell Line
laminin beta2
26 Citations (Scopus)

Breast cancer among hispanic and non-hispanic white women in Arizona

Martínez, M. E., Nielson, C. M., Nagle, R. B., Lopez, A. M., Kim, C. & Thompson, P., Nov 2007, In : Journal of Health Care for the Poor and Underserved. 18, 4 SUPPL., p. 130-145 16 p.

Research output: Contribution to journalArticle

Hispanic Americans
cancer
Breast Neoplasms
Neoplasms
underage
17 Citations (Scopus)

CD44 Promotes Epithelial Mammary Gland Development and Exhibits Altered Localization during Cancer Progression

Louderbough, J. M. V., Brown, J. A., Nagle, R. B. & Schroeder, J., Aug 2011, In : Genes and Cancer. 2, 8, p. 771-781 11 p.

Research output: Contribution to journalArticle

Human Mammary Glands
Neoplasms
Prostatic Neoplasms
Breast Neoplasms
Stromal Cells
8 Citations (Scopus)

Cell line-specific translation of two laminin 5 β3 chain isoforms

Hao, J., McDaniel, K., Weyer, C., Barrera, J. & Nagle, R. B., Jan 23 2002, In : Gene. 283, 1-2, p. 237-244 8 p.

Research output: Contribution to journalArticle

Protein Isoforms
Cell Line
Complementary DNA
Clone Cells
RNA Isoforms
216 Citations (Scopus)

Cellular adaptations to hypoxia and acidosis during somatic evolution of breast cancer

Gatenby, R. A., Smallbone, K., Maini, P. K., Rose, F., Averill, J., Nagle, R. B., Worrall, L. & Gillies, R. J., Aug 28 2007, In : British Journal of Cancer. 97, 5, p. 646-653 8 p.

Research output: Contribution to journalArticle

Clonal Evolution
Acidosis
Breast Neoplasms
Sodium-Hydrogen Antiporter
Carcinoma, Intraductal, Noninfiltrating
4 Citations (Scopus)

Cellular and genetic properties of two melanoma cell lines established from the same tumor

Ludwig, C., Harper, J., Payne, C., Nagle, R. B., Bastert, G. & Trent, J., 1988, In : Anticancer Research. 8, 1, p. 9-16 8 p.

Research output: Contribution to journalArticle

Melanoma
Agar
Cell Line
Biopsy
Neoplasms

Centrosome loss results in an unstable genome and malignant prostate tumors

Wang, M., Nagle, R. B., Knudsen, B. S., Cress, A. E. & Rogers, G. C., Jan 1 2019, (Accepted/In press) In : Oncogene.

Research output: Contribution to journalArticle

Centrosome
Prostate
Genome
Neoplasms
Chromosomal Instability
1 Citation (Scopus)

Characterization of a novel radiation-induced sarcoma cell line

Lang, J., Zhu, W., Nokes, B., Sheth, G., Novak, P., Fuchs, L., Watts, G. S., Futscher, B. W., Mineyev, N., Ring, A., Lebeau, L., Nagle, R. B. & Cranmer, L. D., May 1 2015, In : Journal of Surgical Oncology. 111, 6, p. 669-682 14 p.

Research output: Contribution to journalArticle

Sarcoma
Radiation
Cell Line
Neoplasms
SCID Mice
213 Citations (Scopus)

Characterization of breast carcinomas by two monoclonal antibodies distinguishing myoepithelial from luminal epithelial cells

Nagle, R. B., Bocker, W., Davis, J. R., Heid, H. W., Kaufmann, M., Lucas, D. O. & Jarasch, E. D., 1986, In : Journal of Histochemistry and Cytochemistry. 34, 7, p. 869-881 13 p.

Research output: Contribution to journalArticle

Neoplasm Proteins
Neoplasm Antibodies
Carcinoma, Intraductal, Noninfiltrating
Fibroma
Carcinoma in Situ
102 Citations (Scopus)

Characterization of integrin subunits, cellular adhesion and tumorgenicity of four human prostate cell lines

Witkowski, C. M., Rabinovitz, I., Nagle, R. B., Affinito, K. S. D. & Cress, A. E., Nov 1993, In : Journal of Cancer Research and Clinical Oncology. 119, 11, p. 637-644 8 p.

Research output: Contribution to journalArticle

Integrins
Prostate
Cell Line
Laminin
Vitronectin
9 Citations (Scopus)

Characterization of Laminin Binding Integrin Internalization in Prostate Cancer Cells

Das, L., Anderson, T. A., Gard, J. M. C., Sroka, I. C., Strautman, S. R., Nagle, R. B., Morrissey, C., Knudsen, B. S. & Cress, A. E., May 1 2017, In : Journal of Cellular Biochemistry. 118, 5, p. 1038-1049 12 p.

Research output: Contribution to journalArticle

Laminin
Integrins
Prostatic Neoplasms
Cells
Endosomes
7 Citations (Scopus)

Chemical estimation of interstitial and basement membrane collagen in obstructive nephropathy

Man, M., Nagle, R. B. & Adams, E., 1978, In : Experimental and Molecular Pathology. 29, 2, p. 144-148 5 p.

Research output: Contribution to journalArticle

Basement Membrane
Collagen
Tissue
Hydroxyproline
Ligation
18 Citations (Scopus)

Chlorotrifluoroethylene nephrotoxicity in rats: A subacute study

Buckley, L. A., Clayton, J. W., Nagle, R. B. & Gandolfi, A. J., 1982, In : Fundamental and Applied Toxicology. 2, 4, p. 181-186 6 p.

Research output: Contribution to journalArticle

Rats
Fluorides
Metabolism
Necrosis
Mole Rats

Chlorotrifluoroethylene nephrotoxicity in rats: A subacute study

Buckley, L. A., Clayton, J. W., Nagle, R. B. & Gandolfi, A. J., Jul 1982, In : Toxicological Sciences. 2, 4, p. 181-186 6 p.

Research output: Contribution to journalArticle

Rats
Fluorides
Metabolism
Necrosis
Diuresis