Raymond B Nagle &ndash; Research Output

Article

90K/Mac-2 binding protein is expressed in prostate cancer and induces promatrilysin expression

Bair, E. L., Nagle, R. B., Ulmer, T. A., Laferté, S. & Bowden, G. T., Feb 15 2006, In : Prostate. 66, 3, p. 283-293 11 p.

Research output: Contribution to journal › Article

Prostatic Neoplasms

Carrier Proteins

Prostate

Cell Line

Neoplasms

5 Citations (Scopus)

A basal cell defect promotes budding of prostatic intraepithelial neoplasia

Wang, M., Nagle, R. B., Knudsen, B. S., Rogers, G. C. & Cress, A. E., 2017, In : Journal of Cell Science. 130, 1, p. 104-110 7 p.

Research output: Contribution to journal › Article

Prostatic Intraepithelial Neoplasia

Integrins

Cellular Spheroids

Genomic Instability

Keratins

21 Citations (Scopus)

Aberrant expression of fibroblast growth factor receptor-1 in prostate epithelial cells allows induction of promatrilysin expression by fibroblast growth factors

Udayakumar, T. S., Klein, R. D., Maliner, M. S., Nagle, R. B. & Bowden, G. T., Jan 15 2001, In : International Journal of Cancer. 91, 2, p. 187-192 6 p.

Research output: Contribution to journal › Article

Receptor, Fibroblast Growth Factor, Type 1

Fibroblast Growth Factors

Fibroblast Growth Factor Receptors

Prostate

Epithelial Cells

27 Citations (Scopus)

Accuracy of prostate needle biopsy in predicting extracapsular tumor extension at radical retropubic prostatectomy: Application in selecting patients for nerve-sparing surgery

Sanwick, J. M., Dalkin, B. L. & Nagle, R. B., Nov 1998, In : Urology. 52, 5, p. 814-819 6 p.

Research output: Contribution to journal › Article

Needle Biopsy

Prostatectomy

Prostate

Biopsy

Neoplasms

23 Citations (Scopus)

A comprehensive immunotopographic map of human thymus

Wirt, D. P., Grogan, T. M., Nagle, R. B., Copeland, J. G., Richter, L. C., Rangel, C. S., Schuchardt, M., Fosse, J. & Layton, J. M., 1988, In : Journal of Histochemistry and Cytochemistry. 36, 1, p. 1-12 12 p.

Research output: Contribution to journal › Article

Thymus Gland

B-Lymphocytes

Epithelial Cells

T-Lymphocytes

Reticulum

47 Citations (Scopus)

Activation of gelatinase-tissue-inhibitors-of-metalloproteinase complexes by matrilysin

Von Bredow, D. C., Cress, A. E., Howard, E. W., Bowden, G. T. & Nagle, R. B., May 1 1998, In : Biochemical Journal. 331, 3, p. 965-972 8 p.

Research output: Contribution to journal › Article

Matrix Metalloproteinase 7

Tissue Inhibitor of Metalloproteinases

Gelatinases

Matrix Metalloproteinase Inhibitors

Chemical activation

48 Citations (Scopus)

Acute glomerulonephritis with prolonged oliguria. An analysis of 29 cases.

Leonard, C. D., Nagle, R. B., Striker, G. E., Cutler, R. E. & Scribner, B. H., Nov 1970, In : Annals of Internal Medicine. 73, 5, p. 703-711 9 p.

Research output: Contribution to journal › Article

Kidney Function Tests

Oliguria

Anuria

Streptococcal Infections

Uremia

35 Citations (Scopus)

Acute tubular necrosis in the rat kidney following sustained hypotension. Physiologic and morphologic observations

Dobyan, D. C., Nagle, R. B. & Bulger, R. E., 1977, In : Laboratory Investigation. 37, 4, p. 411-422 12 p.

Research output: Contribution to journal › Article

Rectum

Hypotension

Necrosis

Kidney

Smooth Endoplasmic Reticulum

78 Citations (Scopus)

Adhesion molecules, extracellular matrix, and proteases in prostate carcinoma

Nagle, R. B., Knox, J. D., Wolf, C., Bowden, G. T. & Cress, A. E., 1994, In : Journal of Cellular Biochemistry. 56, SUPPL. 19, p. 232-237 6 p.

Research output: Contribution to journal › Article

Matrix Metalloproteinase 7

Integrins

Extracellular Matrix

Prostate

Peptide Hydrolases

48 Citations (Scopus)

Adult-onset acid maltase deficiency: a postmortem study.

DiMauro, S., Stern, L. Z., Mehler, M., Nagle, R. B. & Payne, C., Jan 1978, In : Muscle and Nerve. 1, 1, p. 27-36 10 p.

Research output: Contribution to journal › Article

Glycogen Storage Disease Type II

alpha-Glucosidases

Skeletal Muscle

Muscles

Liver

6 Citations (Scopus)

A human xenograft model for testing early events of epithelial neoplastic invasion

Mccandless, J. R., Cress, A. E., Rabinovitz, I., Payne, C. M., Bowden, G. T., Knox, J. D. & Nagle, R. B., Feb 1997, In : International Journal of Oncology. 10, 2, p. 279-285 7 p.

Research output: Contribution to journal › Article

Heterografts

Diaphragm

SCID Mice

Neoplasms

Basement Membrane

A hypovolemic model of acute tubular necrosis in the absence of renal failure

Dobyan, D. C., Nagle, R. B., Trump, B. F. & Bulger, R. E., 1976, In : Kidney International. 10, 6, p. 556 1 p.

Research output: Contribution to journal › Article

Hypovolemia

Renal Insufficiency

Necrosis

9 Citations (Scopus)

Alteration of the structure and function of guinea pig peritoneal macrophages by a soybean oil emulsion

Strunk, R. C., Payne, C. M., Nagle, R. B. & Kunke, K., 1979, In : American Journal of Pathology. 96, 3, p. 753-770 18 p.

Research output: Contribution to journal › Article

Soybean Oil

Peritoneal Macrophages

Emulsions

Guinea Pigs

Eating

13 Citations (Scopus)

Altered surface expression and increased turnover of the α6β4 integrin in an undifferentiated carcinoma

Witkowski, C. M., Bowden, G. T., Nagle, R. B. & Cress, A. E., 2000, In : Carcinogenesis. 21, 2, p. 325-330 6 p.

Research output: Contribution to journal › Article

Integrins

Carcinoma

Keratinocytes

Papilloma

Hemidesmosomes

1 Citation (Scopus)

A method of quantifying centrosomes at the single-cell level in human normal and cancer tissue

Wang, M., Knudsen, B. S., Nagle, R. B., Rogers, G. C. & Cress, A. E., Mar 21 2019, In : Molecular biology of the cell. 30, 7, p. 811-819 9 p.

Research output: Contribution to journal › Article

Open Access

Centrosome

Neoplasms

Centrioles

Cell Size

Microscopy

2 Citations (Scopus)

Androgens block interleukin-1β-induced promatrilysin expression in prostate carcinoma cells

Stratton, M. S., Greenstein, B., Udayakumar, T. S., Nagle, R. B. & Bowden, G. T., Sep 15 2002, In : Prostate. 53, 1, p. 1-8 8 p.

Research output: Contribution to journal › Article

Interleukin-1

Androgens

Prostate

Interleukin-6

Testosterone

7 Citations (Scopus)

An evaluation of enzymatic and heat epitope retrieval methods for the immunohistochemical staining of the intermediate filaments

Fan, Z., Clark, V. & Nagle, R. B., 1997, In : Applied Immunohistochemistry. 5, 1, p. 49-58 10 p.

Research output: Contribution to journal › Article

Intermediate Filaments

Avidin

Keratins

Formaldehyde

Epitopes

An evaluation of frozen prostate sextant biopsies supplemented with basal cell specific cytokeratin immunohistochemistry

Fanta, P., Nagle, R. B. & Dalkin, B., Feb 1999, In : Journal of Investigative Medicine. 47, 2

Research output: Contribution to journal › Article

Sextants

Biopsy

Keratins

Prostate

Immunohistochemistry

50 Citations (Scopus)

A new rabbit monoclonal antibody (4B5) for the immunohistochemical (IHC) determination of the HER2 status in breast cancer: Comparison with CB11, fluorescence in situ hybridization (FISH), and interlaboratory reproducibility

Powell, W. C., Hicks, D. G., Prescott, N., Tarr, S. M., Laniauskas, S., Williams, T., Short, S., Pettay, J., Nagle, R. B., Dabbs, D. J., Scott, K. M., Brown, R. W., Grogan, T., Roche, P. C. & Tubbs, R. R., Mar 2007, In : Applied Immunohistochemistry and Molecular Morphology. 15, 1, p. 94-102 9 p.

Research output: Contribution to journal › Article

Fluorescence In Situ Hybridization

Monoclonal Antibodies

Staining and Labeling

Breast Neoplasms

Rabbits

1 Citation (Scopus)

A new species of Euchaetes Harris from southern arizona (Erebidae, arctiinae)

Nagle, R. B. & Christian Schmidt, B., Jan 1 2018, In : ZooKeys. 2018, 788, p. 69-77 9 p.

Research output: Contribution to journal › Article

Arctiinae

host plant

egg

new species

larva

47 Citations (Scopus)

Angiogenesis and neovascularization associated with extracellular matrix-modified porous implants

Kidd, K. R., Nagle, R. B. & Williams, S. K., 2002, In : Journal of Biomedical Materials Research. 59, 2, p. 366-377 12 p.

Research output: Contribution to journal › Article

Polytetrafluoroethylene

Polytetrafluoroethylenes

Rats

Tissue

Blood vessels

110 Citations (Scopus)

Anomalous cytokeratin expression in malignant melanoma: one- and two-dimensional western blot analysis and immunohistochemical survey of 100 melanomas.

Zarbo, R. J., Gown, A. M., Nagle, R. B., Visscher, D. W. & Crissman, J. D., Jul 1990, In : Modern Pathology. 3, 4, p. 494-501 8 p.

Research output: Contribution to journal › Article

Keratins

Melanoma

Western Blotting

Carcinoma

Amelanotic Melanoma

189 Citations (Scopus)

A novel tyrosine kinase switch is a mechanism of imatinib resistance in gastrointestinal stromal tumors

Mahadevan, D., Cooke, L., Riley, C., Swart, R., Simons, B., Della Croce, K., Wisner, L., Iorio, M., Shakalya, K., Garewal, H., Nagle, R. B. & Bearss, D., Jun 7 2007, In : Oncogene. 26, 27, p. 3909-3919 11 p.

Research output: Contribution to journal › Article

Gastrointestinal Stromal Tumors

Protein-Tyrosine Kinases

docetaxel

Phosphotransferases

Stromal Cells

Antibodies reactive with intermediate filament proteins: new tools for the pathologist.

Nagle, R. B., Mar 1984, In : Arizona Medicine. 41, 3, p. 177-179 3 p.

Research output: Contribution to journal › Article

Neurofilament Proteins

Intermediate Filament Proteins

Desmin

Glial Fibrillary Acidic Protein

Vimentin

6 Citations (Scopus)

An ultrastructural study of intranuclear rodlets in a malignant extracranial neuroepithelial neoplasm

Payne, C. M. & Nagle, R. B., 1983, In : Ultrastructural Pathology. 5, 1, p. 1-13 13 p.

Research output: Contribution to journal › Article

Neuroepithelial Neoplasms

neoplasms

Physiology

Neurology

Electron microscopy

9 Citations (Scopus)

A pilot study exploring the molecular architecture of the tumor microenvironment in human prostate cancer using laser capture microdissection and reverse phase protein microarray

Pin, E., Stratton, S. P., Belluco, C., Liotta, L., Nagle, R. B., Hodge, K. A., Deng, J., Dong, T., Baldelli, E., Petricoin, E. & Pierobon, M., Dec 1 2016, In : Molecular Oncology. 10, 10, p. 1234 1 p.

Research output: Contribution to journal › Article

Laser Capture Microdissection

Protein Array Analysis

Tumor Microenvironment

Prostatic Neoplasms

Epithelium

1 Citation (Scopus)

A quantitative light- and elecron-microscopic study of type IV nuclear bodies in crescentic glomerulonephritis

Graham, A. R., Payne, C. M. & Nagle, R. B., 1981, In : American Journal of Pathology. 102, 3, p. 359-366 8 p.

Research output: Contribution to journal › Article

Glomerulonephritis

Light

Electron Microscopy

Fibroblasts

Epithelial Cells

A receptor for activated C3 in the human renal glomerular capillary wall.

Gelfand, M. C., Frank, M. M., Nagle, R. B., Shin, M. & Green, I., Nov 1975, In : Proceedings of the Clinical Dialysis and Transplant Forum. 5, p. 102-105 4 p.

Research output: Contribution to journal › Article

Kidney Glomerulus

Complement C3

Fluorescence Microscopy

Fluorescent Antibody Technique

Erythrocytes

46 Citations (Scopus)

A review of intermediate filament biology and their use in pathologic diagnosis

Nagle, R. B., Jan 1994, In : Molecular Biology Reports. 19, 1, p. 3-21 19 p.

Research output: Contribution to journal › Article

Intermediate Filament Proteins

Intermediate Filaments

Immunohistochemistry

Neoplasms

18 Citations (Scopus)

Assessment of S-(1,2-dichlorovinyl)-l-cysteine induced toxic events in rabbit renal cortical slices. Biochemical and histological evaluation of uptake, covalent binding, and toxicity

Wolfgang, G. H. I., Gandolfi, A. J., Nagle, R. B., Brendel, K. & Stevens, J. L., 1990, In : Chemico-Biological Interactions. 75, 2, p. 153-170 18 p.

Research output: Contribution to journal › Article

Poisons

Cysteine

Toxicity

Rabbits

Kidney

23 Citations (Scopus)

Association of long-term administration of the survivin mRNA-targeted antisense oligonucleotide LY2181308 with reversible kidney injury in a patient with metastatic melanoma

Herrington, W. G., Talbot, D. C., Lahn, M. M., Brandt, J. T., Callies, S., Nagle, R. B., Winearls, C. G. & Roberts, I. S. D., Feb 2011, In : American Journal of Kidney Diseases. 57, 2, p. 300-303 4 p.

Research output: Contribution to journal › Article

Antisense Oligonucleotides

Melanoma

Kidney

Messenger RNA

Wounds and Injuries

8 Citations (Scopus)

Association of obesity and smoking with PSA and PSA velocity in men with prostate cancer.

Algotar, A. M., Stratton, S. P., Ranger-Moore, J., Stratton, M. S., Hsu, C-H., Ahmann, F. R., Nagle, R. B. & Thompson, P. A., May 2011, In : American Journal of Men's Health. 5, 3, p. 272-278 7 p.

Research output: Contribution to journal › Article

Prostate-Specific Antigen

smoking

Prostatic Neoplasms

cancer

Obesity

49 Citations (Scopus)

Aurora-A over-expression in high-grade PIN lesions and prostate cancer

Buschhorn, H. M., Klein, R. R., Chambers, S. M., Hardy, M. C., Green, S., Bearss, D. & Nagle, R. B., Sep 1 2005, In : Prostate. 64, 4, p. 341-346 6 p.

Research output: Contribution to journal › Article

Prostatic Intraepithelial Neoplasia

Prostatic Neoplasms

Prostate

Aurora Kinase A

Staining and Labeling

11 Citations (Scopus)

Automated brightfield dual-color in situ hybridization for detection of mouse double minute 2 gene amplification in sarcomas

Zhang, W., McElhinny, A., Nielsen, A., Wang, M., Miller, M., Singh, S., Rueger, R., Rubin, B. P., Wang, Z., Tubbs, R. R., Nagle, R. B., Roche, P., Wu, P. & Pestic-Dragovich, L., Jan 2011, In : Applied Immunohistochemistry and Molecular Morphology. 19, 1, p. 54-61 8 p.

Research output: Contribution to journal › Article

Gene Amplification

Sarcoma

In Situ Hybridization

Color

Chromosomes, Human, Pair 12

4 Citations (Scopus)

Bioactivity and prostate tissue distribution of metformin in a preprostatectomy prostate cancer cohort

Nguyen, M. M., Martinez, J. A., Hsu, C-H., Sokoloff, M., Krouse, R. S., Gibson, B. A., Nagle, R. B., Parnes, H. L., Cordova, C. & Chow, H-H., Jul 7 2017, (Accepted/In press) In : European Journal of Cancer Prevention.

Research output: Contribution to journal › Article

Metformin

Tissue Distribution

Prostate

Prostatic Neoplasms

Biomarkers

21 Citations (Scopus)

Biosynthesis and secretion of laminin and S-laminin by human prostate carcinoma cell lines

Rabinovitz, I., Cress, A. E. & Nagle, R. B., 1994, In : Prostate. 25, 2, p. 97-107 11 p.

Research output: Contribution to journal › Article

Laminin

Prostate

Carcinoma

Cell Line

laminin beta2

26 Citations (Scopus)

Breast cancer among hispanic and non-hispanic white women in Arizona

Martínez, M. E., Nielson, C. M., Nagle, R. B., Lopez, A. M., Kim, C. & Thompson, P., Nov 2007, In : Journal of Health Care for the Poor and Underserved. 18, 4 SUPPL., p. 130-145 16 p.

Research output: Contribution to journal › Article

Hispanic Americans

cancer

Breast Neoplasms

Neoplasms

underage

17 Citations (Scopus)

CD44 Promotes Epithelial Mammary Gland Development and Exhibits Altered Localization during Cancer Progression

Louderbough, J. M. V., Brown, J. A., Nagle, R. B. & Schroeder, J., Aug 2011, In : Genes and Cancer. 2, 8, p. 771-781 11 p.

Research output: Contribution to journal › Article

Human Mammary Glands

Neoplasms

Prostatic Neoplasms

Breast Neoplasms

Stromal Cells

8 Citations (Scopus)

Cell line-specific translation of two laminin 5 β3 chain isoforms

Hao, J., McDaniel, K., Weyer, C., Barrera, J. & Nagle, R. B., Jan 23 2002, In : Gene. 283, 1-2, p. 237-244 8 p.

Research output: Contribution to journal › Article

Protein Isoforms

Cell Line

Complementary DNA

Clone Cells

RNA Isoforms

216 Citations (Scopus)

Cellular adaptations to hypoxia and acidosis during somatic evolution of breast cancer

Gatenby, R. A., Smallbone, K., Maini, P. K., Rose, F., Averill, J., Nagle, R. B., Worrall, L. & Gillies, R. J., Aug 28 2007, In : British Journal of Cancer. 97, 5, p. 646-653 8 p.

Research output: Contribution to journal › Article

Clonal Evolution

Acidosis

Breast Neoplasms

Sodium-Hydrogen Antiporter

Carcinoma, Intraductal, Noninfiltrating

4 Citations (Scopus)

Cellular and genetic properties of two melanoma cell lines established from the same tumor

Ludwig, C., Harper, J., Payne, C., Nagle, R. B., Bastert, G. & Trent, J., 1988, In : Anticancer Research. 8, 1, p. 9-16 8 p.

Research output: Contribution to journal › Article

Melanoma

Agar

Cell Line

Biopsy

Neoplasms

Centrosome loss results in an unstable genome and malignant prostate tumors

Wang, M., Nagle, R. B., Knudsen, B. S., Cress, A. E. & Rogers, G. C., Jan 1 2019, (Accepted/In press) In : Oncogene.

Research output: Contribution to journal › Article

Centrosome

Prostate

Genome

Neoplasms

Chromosomal Instability

1 Citation (Scopus)

Characterization of a novel radiation-induced sarcoma cell line

Lang, J., Zhu, W., Nokes, B., Sheth, G., Novak, P., Fuchs, L., Watts, G. S., Futscher, B. W., Mineyev, N., Ring, A., Lebeau, L., Nagle, R. B. & Cranmer, L. D., May 1 2015, In : Journal of Surgical Oncology. 111, 6, p. 669-682 14 p.

Research output: Contribution to journal › Article

Sarcoma

Radiation

Cell Line

Neoplasms

SCID Mice

213 Citations (Scopus)

Characterization of breast carcinomas by two monoclonal antibodies distinguishing myoepithelial from luminal epithelial cells

Nagle, R. B., Bocker, W., Davis, J. R., Heid, H. W., Kaufmann, M., Lucas, D. O. & Jarasch, E. D., 1986, In : Journal of Histochemistry and Cytochemistry. 34, 7, p. 869-881 13 p.

Research output: Contribution to journal › Article

Neoplasm Proteins

Neoplasm Antibodies

Carcinoma, Intraductal, Noninfiltrating

Fibroma

Carcinoma in Situ

102 Citations (Scopus)

Characterization of integrin subunits, cellular adhesion and tumorgenicity of four human prostate cell lines

Witkowski, C. M., Rabinovitz, I., Nagle, R. B., Affinito, K. S. D. & Cress, A. E., Nov 1993, In : Journal of Cancer Research and Clinical Oncology. 119, 11, p. 637-644 8 p.

Research output: Contribution to journal › Article

Integrins

Prostate

Cell Line

Laminin

Vitronectin

9 Citations (Scopus)

Characterization of Laminin Binding Integrin Internalization in Prostate Cancer Cells

Das, L., Anderson, T. A., Gard, J. M. C., Sroka, I. C., Strautman, S. R., Nagle, R. B., Morrissey, C., Knudsen, B. S. & Cress, A. E., May 1 2017, In : Journal of Cellular Biochemistry. 118, 5, p. 1038-1049 12 p.

Research output: Contribution to journal › Article

Laminin

Integrins

Prostatic Neoplasms

Cells

Endosomes

7 Citations (Scopus)

Chemical estimation of interstitial and basement membrane collagen in obstructive nephropathy

Man, M., Nagle, R. B. & Adams, E., 1978, In : Experimental and Molecular Pathology. 29, 2, p. 144-148 5 p.

Research output: Contribution to journal › Article

Basement Membrane

Collagen

Tissue

Hydroxyproline

Ligation

18 Citations (Scopus)

Chlorotrifluoroethylene nephrotoxicity in rats: A subacute study

Buckley, L. A., Clayton, J. W., Nagle, R. B. & Gandolfi, A. J., 1982, In : Fundamental and Applied Toxicology. 2, 4, p. 181-186 6 p.

Research output: Contribution to journal › Article

Rats

Fluorides

Metabolism

Necrosis

Mole Rats

Chlorotrifluoroethylene nephrotoxicity in rats: A subacute study

Buckley, L. A., Clayton, J. W., Nagle, R. B. & Gandolfi, A. J., Jul 1982, In : Toxicological Sciences. 2, 4, p. 181-186 6 p.

Research output: Contribution to journal › Article

Rats

Fluorides

Metabolism

Necrosis

Diuresis

34 Citations (Scopus)

Chronic toxicity of S-(trans-1,2-dichlorovinyl)-L-cysteine in mice

Jaffe, D. R., Gandolfi, A. J. & Nagle, R. B., 1984, In : Journal of Applied Toxicology. 4, 6, p. 315-319 5 p.

Research output: Contribution to journal › Article

Kidney Tubules

Cataract

Glutathione

Cysteine

Toxicity