Raymond B Nagle

  • 11487 Citations
  • 58 h-Index
1968 …2020

Research output per year

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Research Output

2008

The role of alpha 6 integrin in prostate cancer migration and bone pain in a novel xenograft model

King, T. E., Pawar, S. C., Majuta, L., Sroka, I. C., Wynn, D., Demetriou, M. C., Nagle, R. B., Porreca, F. & Cress, A. E., Oct 28 2008, In : PloS one. 3, 10, e3535.

Research output: Contribution to journalArticle

40 Scopus citations
2007

A new rabbit monoclonal antibody (4B5) for the immunohistochemical (IHC) determination of the HER2 status in breast cancer: Comparison with CB11, fluorescence in situ hybridization (FISH), and interlaboratory reproducibility

Powell, W. C., Hicks, D. G., Prescott, N., Tarr, S. M., Laniauskas, S., Williams, T., Short, S., Pettay, J., Nagle, R. B., Dabbs, D. J., Scott, K. M., Brown, R. W., Grogan, T., Roche, P. C. & Tubbs, R. R., Mar 1 2007, In : Applied Immunohistochemistry and Molecular Morphology. 15, 1, p. 94-102 9 p.

Research output: Contribution to journalArticle

50 Scopus citations

A novel tyrosine kinase switch is a mechanism of imatinib resistance in gastrointestinal stromal tumors

Mahadevan, D., Cooke, L., Riley, C., Swart, R., Simons, B., Della Croce, K., Wisner, L., Iorio, M., Shakalya, K., Garewal, H., Nagle, R. & Bearss, D., Jun 7 2007, In : Oncogene. 26, 27, p. 3909-3919 11 p.

Research output: Contribution to journalArticle

200 Scopus citations

Breast cancer among hispanic and non-hispanic white women in Arizona

Martínez, M. E., Nielson, C. M., Nagle, R., Lopez, A. M., Kim, C. & Thompson, P., Nov 1 2007, In : Journal of health care for the poor and underserved. 18, 4 SUPPL., p. 130-145 16 p.

Research output: Contribution to journalArticle

26 Scopus citations

Cellular adaptations to hypoxia and acidosis during somatic evolution of breast cancer

Gatenby, R. A., Smallbone, K., Maini, P. K., Rose, F., Averill, J., Nagle, R. B., Worrall, L. & Gillies, R. J., Aug 28 2007, In : British journal of cancer. 97, 5, p. 646-653 8 p.

Research output: Contribution to journalArticle

229 Scopus citations

Integrin α6 cleavage: A novel modification to modulate cell migration

Pawar, S. C., Demetriou, M. C., Nagle, R. B., Bowden, G. T. & Cress, A. E., Apr 1 2007, In : Experimental Cell Research. 313, 6, p. 1080-1089 10 p.

Research output: Contribution to journalArticle

46 Scopus citations
50 Scopus citations

Morphine treatment accelerates sarcoma-induced bone pain, bone loss, and spontaneous fracture in a murine model of bone cancer

King, T., Vardanyan, A., Majuta, L., Melemedjian, O., Nagle, R., Cress, A. E., Vanderah, T. W., Lai, J. & Porreca, F., Nov 1 2007, In : Pain. 132, 1-2, p. 154-168 15 p.

Research output: Contribution to journalArticle

77 Scopus citations

Phase II study of erlotinib in patients with malignant pleural mesothelioma: A Southwest Oncology Group study

Garland, L. L., Rankin, C., Gandara, D. R., Rivkin, S. E., Scott, K. M., Nagle, R. B., Klein-Szanto, A. J. P., Testa, J. R., Altomare, D. A. & Borden, E. C., Jun 10 2007, In : Journal of Clinical Oncology. 25, 17, p. 2406-2413 8 p.

Research output: Contribution to journalArticle

173 Scopus citations
2006

90K/Mac-2 binding protein is expressed in prostate cancer and induces promatrilysin expression

Bair, E. L., Nagle, R. B., Ulmer, T. A., Laferté, S. & Bowden, G. T., Feb 15 2006, In : Prostate. 66, 3, p. 283-293 11 p.

Research output: Contribution to journalArticle

22 Scopus citations

Expression of mTOR signaling pathway markers in prostate cancer progression

Kremer, C. L., Klein, R. R., Mendelson, J., Browne, W., Samadzedeh, L. K., Vanpatten, K., Highstrom, L., Pestano, G. A. & Nagle, R. B., Aug 1 2006, In : Prostate. 66, 11, p. 1203-1212 10 p.

Research output: Contribution to journalArticle

135 Scopus citations

Human laminin-5 and laminin-10 mediated gene expression of prostate carcinoma cells

Calaluce, R., Beck, S. K., Bair, E. L., Pandey, R., Greer, K. A., Hoying, A. M., Hoying, J. B., Mount, D. W. & Nagle, R. B., Sep 13 2006, In : Prostate. 66, 13, p. 1381-1390 10 p.

Research output: Contribution to journalArticle

5 Scopus citations

Role of c-Myc in intestinal tumorigenesis of the ApcMin/+ mouse

Ignatenko, N. A., Holubec, H., Besselsen, D. G., Blohm-Mangone, K. A., Padilla-Torres, J. L., Nagle, R. B., De Alboránç, I. M., Guillen-R, J. M. & Gerner, E. W., Dec 2006, In : Cancer Biology and Therapy. 5, 12, p. 1658-1664 7 p.

Research output: Contribution to journalArticle

Open Access
37 Scopus citations
2005

Aurora-A over-expression in high-grade PIN lesions and prostate cancer

Buschhorn, H. M. K., Klein, R. R., Chambers, S. M., Hardy, M. C., Green, S., Bearss, D. & Nagle, R. B., Sep 1 2005, In : Prostate. 64, 4, p. 341-346 6 p.

Research output: Contribution to journalArticle

51 Scopus citations

Membrane type 1 matrix metalloprotease cleaves laminin-10 and promotes cancer cell migration

Bair, E. L., Man, L. C., McDaniel, K., Sekiguchi, K., Cress, A. E., Nagle, R. B. & Bowden, G. T., Apr 2005, In : Neoplasia. 7, 4, p. 380-389 10 p.

Research output: Contribution to journalArticle

48 Scopus citations

Stimulated endothelial cell adhesion and angiogenesis with laminin-5 modification of expanded polytetrafluoroethylene

Kidd, K. R., Dal Ponte, D., Stone, A. L., Hoying, J. B., Nagle, R. B. & Williams, S. K., Sep 1 2005, In : Tissue Engineering. 11, 9-10, p. 1379-1391 13 p.

Research output: Contribution to journalArticle

25 Scopus citations
2004

Erratum: PEAZ-1: A new human prostate neoplastic epithelial cell line (Prostate (2001) 48 (79-92))

Schmelz, M., Cress, A. E., Barrera, J., McDaniel, K. M., Davis, T. L., Fuchs, L., Dalkin, B. L. & Nagle, R. B., Dec 1 2004, In : Prostate. 61, 4, 1 p.

Research output: Contribution to journalComment/debate

Extracellular alpha 6 integrin cleavage by urokinase-type plasminogen activator in human prostate cancer

Demetriou, M. C., Pennington, M. E., Nagle, R. B. & Cress, A. E., Apr 1 2004, In : Experimental Cell Research. 294, 2, p. 550-558 9 p.

Research output: Contribution to journalArticle

45 Scopus citations

Fibroblast Growth Factor-I Transcriptionally Induces Membrane Type-I Matrix Metalloproteinase Expression in Prostate Carcinoma Cell Line

Udayakumar, T. S., Nagle, R. B. & Bowden, G. T., Jan 1 2004, In : Prostate. 58, 1, p. 66-75 10 p.

Research output: Contribution to journalArticle

32 Scopus citations

Identification of human polo-like kinase 1 as a potential therapeutic target in pancreatic cancer

Gray, P. J., Bearss, D. J., Han, H., Nagle, R., Tsao, M. S., Dean, N. & Von Hoff, D. D., May 1 2004, In : Molecular Cancer Therapeutics. 3, 5, p. 641-646 6 p.

Research output: Contribution to journalArticle

88 Scopus citations

Immunohistochemical comparison of vascular and sinusoidal adherens junctions in cavernosal endothelium

Wessells, H., King, S. H., Schmelz, M., Nagle, R. B. & Heimark, R. L., Jan 2004, In : Urology. 63, 1, p. 201-206 6 p.

Research output: Contribution to journalArticle

9 Scopus citations

Kimura disease with advanced renal damage with anti-tubular basement membrane antibody

Dixit, M. P., Scott, K. M., Bracamonte, E., Dixit, N. M., Schumacher, M. J., Hutter, J. & Nagle, R., Dec 1 2004, In : Pediatric Nephrology. 19, 12, p. 1404-1407 4 p.

Research output: Contribution to journalArticle

10 Scopus citations

Laminin-5 β3A expression in LNCaP human prostate carcinoma cells increases cell migration and tumorigenicity

Calaluce, R., Bearss, D. J., Barrera, J., Zhao, Y., Han, H., Beck, S. K., McDaniel, K. & Nagle, R. B., Jan 1 2004, In : Neoplasia. 6, 5, p. 468-479 12 p.

Research output: Contribution to journalArticle

25 Scopus citations

Modern Data Security

Klein, R. R., Mount, D. W. & Nagle, R. B., Mar 1 2004, In : Archives of Pathology and Laboratory Medicine. 128, 3, p. 338-340 3 p.

Research output: Contribution to journalShort survey

1 Scopus citations

Modern data security [2] (multiple letters)

Ulirsch, R. C., Klein, R. R., Mount, D. W. & Nagle, R. B., Oct 1 2004, In : Archives of Pathology and Laboratory Medicine. 128, 10, 1 p.

Research output: Contribution to journalLetter

Mutations in the G-quadruplex silencer element and their relationship to c-MYC overexpression, NM23 repression, and therapeutic rescue

Grand, C. L., Powell, T. J., Nagle, R. B., Bearss, D. J., Tye, D., Gleason-Guzman, M. & Hurley, L. H., Apr 20 2004, In : Proceedings of the National Academy of Sciences of the United States of America. 101, 16, p. 6140-6145 6 p.

Research output: Contribution to journalArticle

53 Scopus citations

Role of the extracellular matrix in prostate carcinogenesis

Nagle, R. B., Jan 1 2004, In : Journal of Cellular Biochemistry. 91, 1, p. 36-40 5 p.

Research output: Contribution to journalReview article

30 Scopus citations

Selenium and selenomethionine levels in prostate cancer patients

Nyman, D. W., Stratton, M. S., Kopplin, M. J., Dalkin, B. L., Nagle, R. B. & Gandolfi, A. J., Jan 1 2004, In : Cancer detection and prevention. 28, 1, p. 8-16 9 p.

Research output: Contribution to journalArticle

46 Scopus citations

The mitotic serine threonine kinase, Aurora-2, is a potential target for drug development in human pancreatic cancer

Rojanala, S., Han, H., Muñoz, R. M., Browne, W., Nagle, R., Von Hoff, D. D. & Bearss, D. J., Apr 1 2004, In : Molecular Cancer Therapeutics. 3, 4, p. 451-457 7 p.

Research output: Contribution to journalArticle

79 Scopus citations
2003

Laminin Alpha-1, Alpha-3, and Alpha-5 chain expression in human prepubetal benign prostate glands and adult benign and malignant prostate glands

Brar, P. K., Dalkin, B. L., Weyer, C., Sallam, K., Virtanen, I. & Nagle, R. B., Apr 1 2003, In : Prostate. 55, 1, p. 65-70 6 p.

Research output: Contribution to journalArticle

25 Scopus citations

Membrane type-1-matrix metalloproteinase expressed by prostate carcinoma cells cleaves human laminin-5 β3 chain and induces cell migration

Udayakumar, T. S., Chen, M. L., Bair, E. L., Von Bredow, D. C., Cress, A. E., Nagle, R. B. & Bowden, G. T., May 1 2003, In : Cancer Research. 63, 9, p. 2292-2299 8 p.

Research output: Contribution to journalArticle

110 Scopus citations

Pharmacological inhibition of FGF receptor signaling inhibits LNCaP prostate tumor growth, promatrilysin, and PSA expression

Udayakumar, T. S., Bair, E. L., Nagle, R. B. & Bowden, G. T., Oct 1 2003, In : Molecular Carcinogenesis. 38, 2, p. 70-77 8 p.

Research output: Contribution to journalArticle

19 Scopus citations

Site-specific positive margins at radical prostatectomy: Assessing cancer-control benefits of wide excision of the neurovascular bundle on a side with cancer on biopsy

Park, E. L., Dalkin, B., Escobar, C. & Nagle, R. B., Feb 1 2003, In : BJU International. 91, 3, p. 219-222 4 p.

Research output: Contribution to journalArticle

27 Scopus citations
2002

Androgens block interleukin-1β-induced promatrilysin expression in prostate carcinoma cells

Stratton, M. S., Greenstein, B., Udayakumar, T. S., Nagle, R. B. & Bowden, G. T., Sep 15 2002, In : Prostate. 53, 1, p. 1-8 8 p.

Research output: Contribution to journalArticle

2 Scopus citations

Angiogenesis and neovascularization associated with extracellular matrix-modified porous implants

Kidd, K. R., Nagle, R. B. & Williams, S. K., Jan 1 2002, In : Journal of Biomedical Materials Research. 59, 2, p. 366-377 12 p.

Research output: Contribution to journalArticle

48 Scopus citations

Cell line-specific translation of two laminin 5 β3 chain isoforms

Hao, J., McDaniel, K., Weyer, C., Barrera, J. & Nagle, R. B., Jan 23 2002, In : Gene. 283, 1-2, p. 237-244 8 p.

Research output: Contribution to journalArticle

8 Scopus citations

Clinical laboratory assays for HER-2/neu amplification and overexpression: Quality assurance, standardization, and proficiency testing

Nagle, R. B., Tubbs, R. R., Roche, P. C., Hsi, E. D., Linden, M. D., Ormsby, A., Pettigrew, N. M., Rickert, R. R., Said, J. W., Bayer-Garner, I. B., Cooley, L. D., Brothman, A. R., Persons, D. L., Vance, G. H., Mascarello, J. T., Rao, K. W., Herrmann, M., Dewald, G. & Park, J. P., Jul 23 2002, In : Archives of Pathology and Laboratory Medicine. 126, 7, p. 803-808 6 p.

Research output: Contribution to journalArticle

89 Scopus citations

Consensual interpretive guidelines for diagnostic immunohistochemistry [3] multiple letters

Nagle, R. B. & Fitzgibbons, P. L., Jun 3 2002, In : American Journal of Surgical Pathology. 26, 6, p. 816-818 3 p.

Research output: Contribution to journalLetter

4 Scopus citations

Culturing precision-cut human prostate slices as an in vitro model of prostate pathobiology

Parrish, A. R., Sallam, K., Nyman, D. W., Orozco, J., Cress, A. E., Dalkin, B. L., Nagle, R. B. & Gandolfi, A. J., Jun 18 2002, In : Cell Biology and Toxicology. 18, 3, p. 205-219 15 p.

Research output: Contribution to journalArticle

26 Scopus citations

Different phenotypes in human prostate cancer: α6 or α3 integrin in cell-extracellular adhesion sites

Schmelz, M., Cress, A. E., Scott, K. M., Bürgery, F., Cui, H., Sallam, K., McDaniel, K. M., Dalkin, B. L. & Nagle, R. B., May 28 2002, In : Neoplasia. 4, 3, p. 243-254 12 p.

Research output: Contribution to journalArticle

63 Scopus citations

Erratum: Identification of differentially expressed genes in pancreatic cancer cells using cDNA microarray (Cancer Research (May 15, 2002) (2890-2896))

Han, H., Bearss, D. J., Browne, L. W., Calaluce, R., Nagle, R. B. & Von Hoff, D. D., Aug 1 2002, In : Cancer Research. 62, 15, 1 p.

Research output: Contribution to journalComment/debate

Fibroblast growth factor-1 induced promatrilysin expression through the activation of extracellular-regulated kinases and STAT3

Udayakumar, T. S., Stratton, M. S., Nagle, R. B. & Bowden, G. T., Jan 29 2002, In : Neoplasia. 4, 1, p. 60-67 8 p.

Research output: Contribution to journalArticle

40 Scopus citations

Identification of differentially expressed genes in pancreatic cancer cells using cDNA microarray

Han, H., Bearss, D. J., Browne, L. W., Calaluce, R., Nagle, R. B. & Von Hoff, D. D., May 15 2002, In : Cancer Research. 62, 10, p. 2890-2896 7 p.

Research output: Contribution to journalArticle

331 Scopus citations
2001

Aberrant expression of fibroblast growth factor receptor-1 in prostate epithelial cells allows induction of promatrilysin expression by fibroblast growth factors

Udayakumar, T. S., Klein, R. D., Maliner, M. S., Nagle, R. B. & Bowden, G. T., Jan 15 2001, In : International Journal of Cancer. 91, 2, p. 187-192 6 p.

Research output: Contribution to journalArticle

21 Scopus citations

Expression of the matrix metalloproteinase promatrilysin in coculture of prostate carcinoma cell lines

Stratton, M. S., Sirvent, H., Udayakumar, T. S., Nagle, R. B. & Bowden, G. T., Aug 22 2001, In : Prostate. 48, 3, p. 206-209 4 p.

Research output: Contribution to journalArticle

11 Scopus citations

Interleukin-1β-induced promatrilysin expression is mediated by NFκB-regulated synthesis of interleukin-6 in the prostate carcinoma cell line, LNCaP1

Maliner-Stratton, M. S., Klein, R. D., Udayakumar, T. S., Nagle, R. B. & Bowden, G. T., Jan 1 2001, In : Neoplasia. 3, 6, p. 509-520 12 p.

Research output: Contribution to journalArticle

21 Scopus citations

Investigation into the mechanism of the loss of laminin 5 (α3β3γ2) expression in prostate cancer

Hao, J., Jackson, L., Calaluce, R., McDaniel, K., Dalkin, B. L. & Nagle, R. B., Jan 1 2001, In : American Journal of Pathology. 158, 3, p. 1129-1135 7 p.

Research output: Contribution to journalArticle

59 Scopus citations

New molecular approaches to tissue analysis

Nagle, R. B., Jan 1 2001, In : Journal of Histochemistry and Cytochemistry. 49, 8, p. 1063-1064 2 p.

Research output: Contribution to journalArticle

Open Access
11 Scopus citations

PEAZ-1: A new human prostate neoplastic epithelial cell line

Schmelz, M., Cress, A. E., Barrera, J., McDaniel, K. M., Davis, T. L., Fuchs, L., Dalkin, B. L. & Nagle, R. B., Jul 1 2001, In : Prostate. 48, 2, p. 79-92 14 p.

Research output: Contribution to journalArticle

8 Scopus citations