Raymond B Nagle

  • 11487 Citations
  • 58 h-Index
1968 …2020

Research output per year

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Research Output

2001

Signal transduction through the Ras/Erk pathway is essential for the mycoestrogen Zearalenone-induced cell-cycle progression in MCF-7 cells

Calaluce, R., Kunkel, M. W., Watts, G. S., Schmelz, M., Hao, J., Barrera, J., Gleason-Guzman, M., Isett, R., Fitchmun, M., Tim Bowden, G., Cress, A. E., Futscher, B. W. & Nagle, R. B., Mar 15 2001, In : Molecular Carcinogenesis. 30, 2, p. 88-98 11 p.

Research output: Contribution to journalArticle

98 Scopus citations

Unique expression pattern of the α6β4 integrin and laminin-5 in human prostate carcinoma

Davis, T. L., Cress, A. E., Dalkin, B. L. & Nagle, R. B., Feb 20 2001, In : Prostate. 46, 3, p. 240-248 9 p.

Research output: Contribution to journalArticle

75 Scopus citations
2000

Altered surface expression and increased turnover of the α6β4 integrin in an undifferentiated carcinoma

Witkowski, C. M., Bowden, G. T., Nagle, R. B. & Cress, A. E., Feb 28 2000, In : Carcinogenesis. 21, 2, p. 325-330 6 p.

Research output: Contribution to journalArticle

13 Scopus citations

Diagnostic frozen prostate sextant biopsies: An approach for preserving protein and RNA for additional studies

Scott, K. M., Fanta, P., Calaluce, R., Dalkin, B., Weinstein, R. S. & Nagle, R. B., Jan 1 2000, In : Prostate. 44, 4, p. 296-302 7 p.

Research output: Contribution to journalArticle

7 Scopus citations

Prognostic factors in colorectal cancer: College of American Pathologists consensus statement 1999

Compton, C. C., Fielding, L. P., Burgart, L. J., Conley, B., Cooper, H. S., Hamilton, S. R., Hammond, M. E. H., Henson, D. E., Hutter, R. V. P., Nagle, R. B., Nielsen, M. L., Sargent, D. J., Taylor, C. R., Welton, M. & Willett, C., Aug 15 2000, In : Archives of Pathology and Laboratory Medicine. 124, 7, p. 979-994 16 p.

Research output: Contribution to journalArticle

937 Scopus citations
1999

EGF induces the expression of matrilysin in the human prostate adenocarcinoma cell line, LNCAP

Sundareshan, P., Nagle, R. B. & Bowden, G. T., Aug 1 1999, In : Prostate. 40, 3, p. 159-166 8 p.

Research output: Contribution to journalArticle

18 Scopus citations

Experimental induction of rhabdomyosarcoma in mice with fractionated doses of β-irradiation

Gupta, A., Andrews, K. L., McDaniel, K. M., Nagle, R. B. & Bowden, G. T., Jun 3 1999, In : Journal of Cancer Research and Clinical Oncology. 125, 5, p. 257-267 11 p.

Research output: Contribution to journalArticle

8 Scopus citations

Induction of melanoma in TPras transgenic mice

Powell, M. B., Gause, P. R., Hyman, P., Gregus, J., Lluria-Prevatt, M., Nagle, R. & Bowden, G. T., Sep 8 1999, In : Carcinogenesis. 20, 9, p. 1747-1753 7 p.

Research output: Contribution to journalArticle

74 Scopus citations
189 Scopus citations

Promatrilysin expression is induced by fibroblast growth factors in the prostatic carcinoma cell line LNCaP but not in normal primary prostate epithelial cells

Klein, R. D., Maliner-Jongewaard, M. S., Udayakumar, T. S., Boyd, J. L., Nagle, R. B. & Bowden, G. T., Dec 10 1999, In : Prostate. 41, 4, p. 215-223 9 p.

Research output: Contribution to journalArticle

19 Scopus citations
1998
27 Scopus citations

Activation of gelatinase-tissue-inhibitors-of-metalloproteinase complexes by matrilysin

Von Bredow, D. C., Cress, A. E., Howard, E. W., Bowden, G. T. & Nagle, R. B., May 1 1998, In : Biochemical Journal. 331, 3, p. 965-972 8 p.

Research output: Contribution to journalArticle

48 Scopus citations

Extension of useful reagent shelf life beyond manufacturers' recommendations

Tubbs, R. R., Nagle, R., Leslie, K., Pettigrew, N. M., Said, J. W., Corwin, D. J., Rickert, R. R. & Roche, P. C., Dec 1 1998, In : Archives of Pathology and Laboratory Medicine. 122, 12, p. 1051-1052 2 p.

Research output: Contribution to journalArticle

7 Scopus citations

Synthetic matrix metalloproteinase inhibitor, BB-94, inhibits the invasion of neoplastic human prostate cells in a mouse model

Knox, J. D., Bretton, L., Lynch, T., Bowden, G. T. & Nagle, R. B., Jun 1 1998, In : Prostate. 35, 4, p. 248-254 7 p.

Research output: Contribution to journalArticle

27 Scopus citations
1997

A human xenograft model for testing early events of epithelial neoplastic invasion

Mccandless, J. R., Cress, A. E., Rabinovitz, I., Payne, C. M., Bowden, G. T., Knox, J. D. & Nagle, R. B., Feb 1 1997, In : International journal of oncology. 10, 2, p. 279-285 7 p.

Research output: Contribution to journalArticle

7 Scopus citations
7 Scopus citations

Cleavage of β4 integrin by matrilysin

Von Bredow, D. C., Nagle, R. B., Bowden, G. T. & Cress, A. E., Oct 10 1997, In : Experimental Cell Research. 236, 1, p. 341-345 5 p.

Research output: Contribution to journalArticle

101 Scopus citations

Coordinated expression of matrilysin during TPA-induced apoptosis of LNCaP cells: Two parallel processes affected by TPA

Sundareshan, P., Koster, J. J., Nagle, R. B. & Bowden, G. T., Feb 26 1997, In : Cancer Letters. 113, 1-2, p. 17-24 8 p.

Research output: Contribution to journalArticle

8 Scopus citations

Diagnostic accuracy of an international static-imaging telepathology consultation service

Halliday, B. E., Bhahacharyya, A. K., Graham, A. R., Davis, J. R., Anne Leavitt, S., Nagle, R. B., McLaughlin, W. J., Rivas, R. A., Martinez, R., Krupinski, E. A. & Weinstein, R. S., Jan 1 1997, In : Human pathology. 28, 1, p. 17-21 5 p.

Research output: Contribution to journalArticle

118 Scopus citations

Differential expression of cytokeratin mRNA and protein in normal prostate, prostatic intraepithelial neoplasia, and invasive carcinoma

Yang, Y., Hao, J., Liu, X., Dalkin, B. & Nagle, R. B., Feb 21 1997, In : American Journal of Pathology. 150, 2, p. 693-704 12 p.

Research output: Contribution to journalArticle

45 Scopus citations

Effects of acute and chronic arsenic exposure of human-derived keratinocytes in an in vitro human skin equivalent system: A novel model of human arsenicism

Klimecki, W. T., Borchers, A. H., Egbert, R. E., Nagle, R. B., Carter, D. E. & Bowden, G. T., Feb 1 1997, In : Toxicology in Vitro. 11, 1-2, p. 89-98 10 p.

Research output: Contribution to journalArticle

21 Scopus citations

Interleukin-1β secreted from monocytic cells induces the expression of matrilysin in the prostatic cell line LNCaP

Klein, R. D., Borchers, A. H., Sundareshan, P., Bougelet, C., Berkman, M. R., Nagle, R. B. & Bowden, G. T., May 30 1997, In : Journal of Biological Chemistry. 272, 22, p. 14188-14192 5 p.

Research output: Contribution to journalArticle

25 Scopus citations

Pathologic and clinical findings in patients with cyclosporiasis and a description of intracellular parasite life-cycle stages

Ortega, Y. R., Nagle, R., Gilman, R. H., Watanabe, J., Miyagui, J., Quispe, H., Kanagusuku, P., Roxas, C. & Sterling, C. R., Jan 1 1997, In : Journal of Infectious Diseases. 176, 6, p. 1584-1589 6 p.

Research output: Contribution to journalArticle

Open Access
69 Scopus citations
1996

Differential expression of laminin 5 (α3β3γ2) by human malignant and normal prostate

Hao, J., Yang, Y., McDaniel, K. M., Dalkin, B. L., Cress, A. E. & Nagle, R. B., Oct 1 1996, In : American Journal of Pathology. 149, 4, p. 1341-1349 9 p.

Research output: Contribution to journalArticle

93 Scopus citations

Intermediate filament expression in prostate cancer

Nagle, R. B., Dec 1 1996, In : Cancer and Metastasis Reviews. 15, 4, p. 473-482 10 p.

Research output: Contribution to journalReview article

13 Scopus citations

Mapping of the metalloproteinase gene matrilysin (MMP7) to human chromosome 11q21→q22

Knox, J. D., Boreham, D. R., Walker, J. A., Morrison, D. P., Matrisian, L. M., Nagle, R. B. & Bowden, G. T., Jan 1 1996, In : Cytogenetic and Genome Research. 72, 2-3, p. 179-182 4 p.

Research output: Contribution to journalArticle

20 Scopus citations

Matrilysin expression in human prostate carcinoma

Knox, J. D., Wolf, C., McDaniel, K., Clark, V., Loriot, M., Bowden, G. T. & Nagle, R. B., Jan 1 1996, In : Molecular Carcinogenesis. 15, 1, p. 57-63 7 p.

Research output: Contribution to journalArticle

70 Scopus citations

Matrilysin expression in the involuting rat ventral prostate

Powell, W. C., Domann, F. E., Mitchen, J. M., Matrisian, L. M., Nagle, R. B. & Bowden, G. T., Sep 1 1996, In : Prostate. 29, 3, p. 159-168 10 p.

Research output: Contribution to journalArticle

37 Scopus citations

Phrynosoma intraepidermal receptor: A dorsal intraepidermal mechanoreceptor in horned lizards (Phrynosoma; Phrynosomatidae; Reptilia)

Sherbrooke, W. C. & Nagle, R. B., May 1996, In : Journal of Morphology. 228, 2, p. 145-154 10 p.

Research output: Contribution to journalArticle

8 Scopus citations

Randomized study of neoadjuvant testicular androgen ablation therapy before radical prostatectomy in men with clinically localized prostate cancer

Dalkin, B. L., Ahmann, F. R., Nagle, R. & Johnson, C. S., Apr 1996, In : Journal of Urology. 155, 4, p. 1357-1360 4 p.

Research output: Contribution to journalArticle

75 Scopus citations
1995

Degradation of Fibronectin Fibrils by Matrilysin and Characterization of the Degradation Products

von Bredow, D. C., Nagle, R. B., Bowden, G. T. & Cress, A. E., Nov 1995, In : Experimental Cell Research. 221, 1, p. 83-91 9 p.

Research output: Contribution to journalArticle

24 Scopus citations

Expression of hemidesmosomal and extracellular matrix proteins by normal and malignant human prostate tissue

Nagle, R. B., Hao, J., Knox, J. D., Dalkin, B. L., Clark, V. & Cress, A. E., Jan 1 1995, In : American Journal of Pathology. 146, 6, p. 1498-1507 10 p.

Research output: Contribution to journalArticle

119 Scopus citations
102 Scopus citations

The α6β1 and α6β4 integrins in human prostate cancer progression

Cress, A. E., Rabinovitz, I., Zhu, W. & Nagle, R. B., Sep 1 1995, In : Cancer and Metastasis Reviews. 14, 3, p. 219-228 10 p.

Research output: Contribution to journalArticle

151 Scopus citations

Working Standards in Prostatic Intraepithelial Neoplasia and Atypical Adenomatous Hyperplasia

Algaba, F., Epstein, J. I., Fabus, G., Helpap, B., Nagle, R. B. & Polito, M., Jan 1 1995, In : Pathology Research and Practice. 191, 9, p. 836-837 2 p.

Research output: Contribution to journalArticle

13 Scopus citations
1994

Adhesion molecules, extracellular matrix, and proteases in prostate carcinoma

Nagle, R. B., Knox, J. D., Wolf, C., Bowden, G. T. & Cress, A. E., Jan 1 1994, In : Journal of Cellular Biochemistry. 56, SUPPL. 19, p. 232-237 6 p.

Research output: Contribution to journalArticle

79 Scopus citations

A review of intermediate filament biology and their use in pathologic diagnosis

Nagle, R. B., Jan 1994, In : Molecular Biology Reports. 19, 1, p. 3-21 19 p.

Research output: Contribution to journalReview article

47 Scopus citations

Biosynthesis and secretion of laminin and S‐laminin by human prostate carcinoma cell lines

Rabinovitz, I., Cress, A. E. & Nagle, R. B., Aug 1994, In : The Prostate. 25, 2, p. 97-107 11 p.

Research output: Contribution to journalArticle

21 Scopus citations

Differential expression of extracellular matrix molecules and the α6- integrins in the normal and neoplastic prostate

Knox, J. D., Cress, A. E., Clark, V., Manriquez, L., Affinito, K. S., Dalkin, B. L. & Nagle, R. B., Jan 1 1994, In : American Journal of Pathology. 145, 1, p. 167-174 8 p.

Research output: Contribution to journalArticle

144 Scopus citations

Histopathology of localized prostate cancer

Murphy, G. P., Busch, C., Abrahamsson, P. A., Epstein, J. I., McNeal, J. E., Miller, G. J., Mostofi, F. K., Nagle, R. B., Nordling, S., Parkinson, C. & Sesterhenn, I. A., Jan 1 1994, In : Scandinavian Journal of Urology and Nephrology, Supplement. 162, p. 7-42 36 p.

Research output: Contribution to journalArticle

52 Scopus citations

Histopathology of localized prostate cancer. Consensus Conference on Diagnosis and Prognostic Parameters in Localized Prostate Cancer. Stockholm, Sweden, May 12-13, 1993.

Murphy, G. P., Busch, C., Abrahamsson, P. A., Epstein, J. I., McNeal, J. E., Miller, G. J., Mostofi, F. K., Nagle, R. B., Nordling, S. & Parkinson, C., 1994, In : Scandinavian Journal of Urology and Nephrology, Supplement. 162, p. 7-42 36 p.

Research output: Contribution to journalArticle

Immunohistochemical analysis of cathepsin D in prostate carcinoma.

Makar, R., Mason, A., Kittelson, J. M., Bowden, G. T., Cress, A. E. & Nagle, R. B., Sep 1994, In : Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc. 7, 7, p. 747-751 5 p.

Research output: Contribution to journalArticle

22 Scopus citations

Nephrotoxicity and uptake of 1-benzyl quinolinium in precision-cut rabbit renal cortical slices

Sheevers, H. V., Brendel, K., Wright, S. H., Nagle, R. B. & Gandolfi, A. J., Dec 1994, In : Toxicology in Vitro. 8, 6, p. 1243-1251 9 p.

Research output: Contribution to journalArticle

2 Scopus citations

The most promising surrogate endpoint biomarkers for screening candidate chemopreventive compounds for prostatic adenocarcinoma in short-term phase II clinical trials

Bostwick, D. G., Burke, H. B., Wheeler, T. M., Chung, L. W. K., Bookstein, R., Pretlow, T. G., Nagle, R. B., Montironi, R., Lieber, M. M., Veltri, R. W., Grizzle, W. E. & Grignon, D. J., Jan 1 1994, In : Journal of Cellular Biochemistry. 56, SUPPL. 19, p. 283-289 7 p.

Research output: Contribution to journalArticle

41 Scopus citations
1993

Characterization of integrin subunits, cellular adhesion and tumorgenicity of four human prostate cell lines

Witkowski, C. M., Rabinovitz, I., Nagle, R. B., Affinito, K. S. D. & Cress, A. E., Nov 1 1993, In : Journal of Cancer Research and Clinical Oncology. 119, 11, p. 637-644 8 p.

Research output: Contribution to journalArticle

103 Scopus citations

Ciprofloxacin-Induced Granulomatous Interstitial Nephritis and Localized Elastolysis

Lien, Y. H. H., Hansen, R., Kern, W. F., Bangert, J., Nagle, R. B., Ko, M. & Siskind, M. S., 1993, In : American Journal of Kidney Diseases. 22, 4, p. 598-602 5 p.

Research output: Contribution to journalArticle

32 Scopus citations

Endothelial transdifferentiated phenotype and cell-cycle kinetics of AIDS- associated Kaposi sarcoma cells

Way, D. L., Witte, M. H., Fiala, M., Ramirez, G., Nagle, R. B., Bernas, M. J., Dictor, M., Borgs, P. & Witte, C. L., Jan 1 1993, In : Lymphology. 26, 2, p. 79-89 11 p.

Research output: Contribution to journalArticle

16 Scopus citations

Expression of the Metalloproteinase Matrilysin in DU-145 Cells Increases Their Invasive Potential in Severe Combined Immunodeficient Mice

Powell, W. C., Knox, J. D., Navre, M., Grogan, T. M., Kittelson, J. & Nagle, R. B., Jan 1993, In : Cancer Research. 53, 2, p. 417-422 6 p.

Research output: Contribution to journalArticle

180 Scopus citations

Prostate tumor cell invasion: A comparison of orthotopic and ectopic models

Knox, J. D., Mack, C. F., Powell, W. C., Bowden, G. T. & Nagle, R. B., Dec 1 1993, In : Invasion and Metastasis. 13, 6, p. 325-331 7 p.

Research output: Contribution to journalArticle

23 Scopus citations