Raymond B Nagle

  • 11228 Citations
  • 57 h-Index
1968 …2021
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Research Output 1968 2019

  • 11228 Citations
  • 57 h-Index
  • 271 Article
  • 3 Chapter
  • 1 Conference contribution
  • 1 Review article
2001
71 Citations (Scopus)

Unique expression pattern of the α6β4 integrin and laminin-5 in human prostate carcinoma

Davis, T. L., Cress, A. E., Dalkin, B. L. & Nagle, R. B., 2001, In : Prostate. 46, 3, p. 240-248 9 p.

Research output: Contribution to journalArticle

Integrins
Prostate
Carcinoma
Prostatic Intraepithelial Neoplasia
Breast Neoplasms
2000
13 Citations (Scopus)

Altered surface expression and increased turnover of the α6β4 integrin in an undifferentiated carcinoma

Witkowski, C. M., Bowden, G. T., Nagle, R. B. & Cress, A. E., 2000, In : Carcinogenesis. 21, 2, p. 325-330 6 p.

Research output: Contribution to journalArticle

Integrins
Carcinoma
Keratinocytes
Papilloma
Hemidesmosomes
7 Citations (Scopus)

Diagnostic frozen prostate sextant biopsies: An approach for preserving protein and RNA for additional studies

Scott, K. M., Fanta, P., Calaluce, R., Dalkin, B., Weinstein, R. S. & Nagle, R. B., 2000, In : Prostate. 44, 4, p. 296-302 7 p.

Research output: Contribution to journalArticle

Prostatic Intraepithelial Neoplasia
Prostate
RNA
Carcinoma
Biopsy
912 Citations (Scopus)

Prognostic factors in colorectal cancer: College of American Pathologists consensus statement 1999

Compton, C. C., Fielding, L. P., Burgart, L. J., Conley, B., Cooper, H. S., Hamilton, S. R., Hammond, M. E. H., Henson, D. E., Hutter, R. V. P., Nagle, R. B., Nielsen, M. L., Sargent, D. J., Taylor, C. R., Welton, M. & Willett, C., 2000, In : Archives of Pathology and Laboratory Medicine. 124, 7, p. 979-994 16 p.

Research output: Contribution to journalArticle

Colorectal Neoplasms
Neoplasms
Microsatellite Instability
Neoplasm Staging
Loss of Heterozygosity
1999
Sextants
Biopsy
Keratins
Prostate
Immunohistochemistry
18 Citations (Scopus)

EGF induces the expression of matrilysin in the human prostate adenocarcinoma cell line, LNCAP

Sundareshan, P., Nagle, R. B. & Bowden, G. T., Aug 1 1999, In : Prostate. 40, 3, p. 159-166 8 p.

Research output: Contribution to journalArticle

Matrix Metalloproteinase 7
Epidermal Growth Factor
Prostate
Adenocarcinoma
Cell Line
8 Citations (Scopus)

Experimental induction of rhabdomyosarcoma in mice with fractionated doses of β-irradiation

Gupta, A., Andrews, K. L., McDaniel, K. M., Nagle, R. B. & Bowden, G. T., 1999, In : Journal of Cancer Research and Clinical Oncology. 125, 5, p. 257-267 11 p.

Research output: Contribution to journalArticle

Rhabdomyosarcoma
Radiation
Sarcoma
Malignant Fibrous Histiocytoma
Neoplasms
72 Citations (Scopus)

Induction of melanoma in TPras transgenic mice

Powell, M. B., Gause, P. R., Hyman, P., Gregus, J., Lluria-Prevatt, M., Nagle, R. B. & Bowden, G. T., 1999, In : Carcinogenesis. 20, 9, p. 1747-1753 7 p.

Research output: Contribution to journalArticle

Transgenic Mice
Melanocytes
Melanoma
Papilloma
Tetradecanoylphorbol Acetate
186 Citations (Scopus)
Epithelial-Mesenchymal Transition
Cadherins
Stromal Cells
Prostate
Carcinoma
19 Citations (Scopus)

Promatrilysin expression is induced by fibroblast growth factors in the prostatic carcinoma cell line LNCaP but not in normal primary prostate epithelial cells

Klein, R. D., Maliner-Jongewaard, M. S., Udayakumar, T. S., Boyd, J. L., Nagle, R. B. & Bowden, G. T., 1999, In : Prostate. 41, 4, p. 215-223 9 p.

Research output: Contribution to journalArticle

Fibroblast Growth Factors
Prostate
Epithelial Cells
Carcinoma
Cell Line
1998
27 Citations (Scopus)
Needle Biopsy
Prostatectomy
Prostate
Biopsy
Neoplasms
47 Citations (Scopus)

Activation of gelatinase-tissue-inhibitors-of-metalloproteinase complexes by matrilysin

Von Bredow, D. C., Cress, A. E., Howard, E. W., Bowden, G. T. & Nagle, R. B., May 1 1998, In : Biochemical Journal. 331, 3, p. 965-972 8 p.

Research output: Contribution to journalArticle

Matrix Metalloproteinase 7
Tissue Inhibitor of Metalloproteinases
Gelatinases
Matrix Metalloproteinase Inhibitors
Chemical activation
7 Citations (Scopus)

Extension of useful reagent shelf life beyond manufacturers' recommendations

Tubbs, R. R., Nagle, R. B., Leslie, K., Pettigrew, N. M., Said, J. W., Corwin, D. J., Rickert, R. R. & Roche, P. C., 1998, In : Archives of Pathology and Laboratory Medicine. 122, 12, p. 1051-1052 2 p.

Research output: Contribution to journalArticle

CD45 Antigens
Angiomyolipoma
Centers for Medicare and Medicaid Services (U.S.)
S100 Proteins
Antibodies
27 Citations (Scopus)

Synthetic matrix metalloproteinase inhibitor, BB-94, inhibits the invasion of neoplastic human prostate cells in a mouse model

Knox, J. D., Bretton, L., Lynch, T., Bowden, G. T. & Nagle, R. B., Jun 1 1998, In : Prostate. 35, 4, p. 248-254 7 p.

Research output: Contribution to journalArticle

Matrix Metalloproteinase Inhibitors
Prostate
Metalloproteases
Diaphragm
Matrix Metalloproteinase 7
1997
6 Citations (Scopus)

A human xenograft model for testing early events of epithelial neoplastic invasion

Mccandless, J. R., Cress, A. E., Rabinovitz, I., Payne, C. M., Bowden, G. T., Knox, J. D. & Nagle, R. B., Feb 1997, In : International Journal of Oncology. 10, 2, p. 279-285 7 p.

Research output: Contribution to journalArticle

Heterografts
Diaphragm
SCID Mice
Neoplasms
Basement Membrane
7 Citations (Scopus)
Intermediate Filaments
Avidin
Keratins
Formaldehyde
Epitopes
100 Citations (Scopus)

Cleavage of β4 integrin by matrilysin

Von Bredow, D. C., Nagle, R. B., Bowden, G. T. & Cress, A. E., Oct 10 1997, In : Experimental Cell Research. 236, 1, p. 341-345 5 p.

Research output: Contribution to journalArticle

Matrix Metalloproteinase 7
Integrins
Prostate
Carcinoma
Isoleucine
8 Citations (Scopus)

Coordinated expression of matrilysin during TPA-induced apoptosis of LNCaP cells: Two parallel processes affected by TPA

Sundareshan, P., Koster, J. J., Nagle, R. B. & Bowden, G. T., Feb 26 1997, In : Cancer Letters. 113, 1-2, p. 17-24 8 p.

Research output: Contribution to journalArticle

Matrix Metalloproteinase 7
Acetates
Apoptosis
Matrix Metalloproteinases
phorbol
117 Citations (Scopus)

Diagnostic accuracy of an international static-imaging telepathology consultation service

Halliday, B. E., Bhahacharyya, A. K., Graham, A. R., Davis, J. R., Anne Leavitt, S., Nagle, R. B., McLaughlin, W. J., Rivas, R. A., Martinez, R., Krupinski, E. A. & Weinstein, R. S., 1997, In : Human Pathology. 28, 1, p. 17-21 5 p.

Research output: Contribution to journalArticle

Telepathology
Referral and Consultation
Glass
Selection Bias
Microscopy
44 Citations (Scopus)

Differential expression of cytokeratin mRNA and protein in normal prostate, prostatic intraepithelial neoplasia, and invasive carcinoma

Yang, Y., Hao, J., Liu, X., Dalkin, B. & Nagle, R. B., 1997, In : American Journal of Pathology. 150, 2, p. 693-704 12 p.

Research output: Contribution to journalArticle

Prostatic Intraepithelial Neoplasia
Keratins
Prostate
Carcinoma
Messenger RNA
21 Citations (Scopus)

Effects of acute and chronic arsenic exposure of human-derived keratinocytes in an in vitro human skin equivalent system: A novel model of human arsenicism

Klimecki, W., Borchers, A. H., Egbert, R. E., Nagle, R. B., Carter, D. E. & Bowden, G. T., Feb 1997, In : Toxicology in Vitro. 11, 1-2, p. 89-98 10 p.

Research output: Contribution to journalArticle

Arsenic
Keratinocytes
Skin
Dynamic mechanical analysis
Keratin-16
25 Citations (Scopus)

Interleukin-1β secreted from monocytic cells induces the expression of matrilysin in the prostatic cell line LNCaP

Klein, R. D., Borchers, A. H., Sundareshan, P., Bougelet, C., Berkman, M. R., Nagle, R. B. & Bowden, G. T., May 30 1997, In : Journal of Biological Chemistry. 272, 22, p. 14188-14192 5 p.

Research output: Contribution to journalArticle

Matrix Metalloproteinase 7
Interleukin-1
Cells
Cell Line
Prostate
66 Citations (Scopus)

Pathologic and clinical findings in patients with cyclosporiasis and a description of intracellular parasite life-cycle stages

Ortega, Y. R., Nagle, R. B., Gilman, R. H., Watanabe, J., Miyagui, J., Quispe, H., Kanagusuku, P., Roxas, C. & Sterling, C. R., 1997, In : Journal of Infectious Diseases. 176, 6, p. 1584-1589 6 p.

Research output: Contribution to journalArticle

Cyclosporiasis
Cyclospora
Life Cycle Stages
Parasites
Diarrhea
1996
92 Citations (Scopus)

Differential expression of laminin 5 (α3β3γ2) by human malignant and normal prostate

Hao, J., Yang, Y., McDaniel, K. M., Dalkin, B. L., Cress, A. E. & Nagle, R. B., Oct 1996, In : American Journal of Pathology. 149, 4, p. 1341-1349 9 p.

Research output: Contribution to journalArticle

Prostate
Carcinoma
Hemidesmosomes
Basement Membrane
Prostatic Intraepithelial Neoplasia
13 Citations (Scopus)

Intermediate filament expression in prostate cancer

Nagle, R. B., 1996, In : Cancer and Metastasis Reviews. 15, 4, p. 473-482 10 p.

Research output: Contribution to journalArticle

Intermediate Filaments
Prostate
Prostatic Neoplasms
Prostatic Intraepithelial Neoplasia
Carcinoma
20 Citations (Scopus)

Mapping of the metalloproteinase gene matrilysin (MMP7) to human chromosome 11q21→q22

Knox, J. D., Boreham, D. R., Walker, J. A., Morrison, D. P., Matrisian, L. M., Nagle, R. B. & Bowden, G. T., 1996, In : Cytogenetics and Cell Genetics. 72, 2-3, p. 179-182 4 p.

Research output: Contribution to journalArticle

Matrix Metalloproteinase 7
Chromosome Mapping
Human Chromosomes
Metalloproteases
Matrix Metalloproteinases
70 Citations (Scopus)

Matrilysin expression in human prostate carcinoma

Knox, J. D., Wolf, C., McDaniel, K., Clark, V., Loriot, M., Bowden, G. T. & Nagle, R. B., Jan 1996, In : Molecular Carcinogenesis. 15, 1, p. 57-63 7 p.

Research output: Contribution to journalArticle

Matrix Metalloproteinase 7
Prostate
Carcinoma
Matrix Metalloproteinase 2
Neoplasms
37 Citations (Scopus)

Matrilysin expression in the involuting rat ventral prostate

Powell, W. C., Domann, F. E., Mitchen, J. M., Matrisian, L. M., Nagle, R. B. & Bowden, G. T., Sep 1996, In : Prostate. 29, 3, p. 159-168 10 p.

Research output: Contribution to journalArticle

Matrix Metalloproteinase 7
Prostate
Castration
Messenger RNA
Matrix Metalloproteinases
8 Citations (Scopus)

Phrynosoma intraepidermal receptor: A dorsal intraepidermal mechanoreceptor in horned lizards (Phrynosoma; Phrynosomatidae; Reptilia)

Sherbrooke, W. C. & Nagle, R. B., May 1996, In : Journal of Morphology. 228, 2, p. 145-154 10 p.

Research output: Contribution to journalArticle

mechanoreceptors
Mechanoreceptors
Reptiles
Lizards
Reptilia
74 Citations (Scopus)

Randomized study of neoadjuvant testicular androgen ablation therapy before radical prostatectomy in men with clinically localized prostate cancer

Dalkin, B. L., Ahmann, F. R., Nagle, R. B. & Johnson, C. S., Apr 1996, In : Journal of Urology. 155, 4, p. 1357-1360 4 p.

Research output: Contribution to journalArticle

Prostatectomy
Androgens
Prostatic Neoplasms
Prostate-Specific Antigen
Gonadotropin-Releasing Hormone
1995
23 Citations (Scopus)

Degradation of Fibronectin Fibrils by Matrilysin and Characterization of the Degradation Products

von Bredow, D. C., Nagle, R. B., Bowden, G. T. & Cress, A. E., Nov 1995, In : Experimental Cell Research. 221, 1, p. 83-91 9 p.

Research output: Contribution to journalArticle

Matrix Metalloproteinase 7
Fibronectins
Foreskin
Metalloproteases
Fibroblasts
115 Citations (Scopus)

Expression of hemidesmosomal and extracellular matrix proteins by normal and malignant human prostate tissue

Nagle, R. B., Hao, J., Knox, J. D., Dalkin, B. L., Clark, V. & Cress, A. E., 1995, In : American Journal of Pathology. 146, 6, p. 1498-1507 10 p.

Research output: Contribution to journalArticle

Extracellular Matrix Proteins
Prostate
Carcinoma
Basement Membrane
Plectin
102 Citations (Scopus)
Integrins
Prostate
Carcinoma
Phenotype
Laminin
147 Citations (Scopus)

The α6β1 and α6β4 integrins in human prostate cancer progression

Cress, A. E., Rabinovitz, I., Zhu, W. & Nagle, R. B., Sep 1995, In : Cancer and Metastasis Reviews. 14, 3, p. 219-228 10 p.

Research output: Contribution to journalArticle

Integrins
Prostatic Neoplasms
Laminin
Carcinoma
Prostatic Intraepithelial Neoplasia
13 Citations (Scopus)

Working standards in prostatic intraepithelial neoplasia and atypical adenomatous hyperplasia

Algaba, F., Epstein, J. I., Fabus, G., Helpap, B., Nagle, R. B. & Polito, M., 1995, In : Pathology Research and Practice. 191, 9, p. 836-837 2 p.

Research output: Contribution to journalArticle

Prostatic Intraepithelial Neoplasia
Hyperplasia
Research
1994
78 Citations (Scopus)

Adhesion molecules, extracellular matrix, and proteases in prostate carcinoma

Nagle, R. B., Knox, J. D., Wolf, C., Bowden, G. T. & Cress, A. E., 1994, In : Journal of Cellular Biochemistry. 56, SUPPL. 19, p. 232-237 6 p.

Research output: Contribution to journalArticle

Matrix Metalloproteinase 7
Integrins
Extracellular Matrix
Prostate
Peptide Hydrolases
46 Citations (Scopus)

A review of intermediate filament biology and their use in pathologic diagnosis

Nagle, R. B., Jan 1994, In : Molecular Biology Reports. 19, 1, p. 3-21 19 p.

Research output: Contribution to journalArticle

Intermediate Filament Proteins
Intermediate Filaments
Immunohistochemistry
Neoplasms
21 Citations (Scopus)

Biosynthesis and secretion of laminin and S-laminin by human prostate carcinoma cell lines

Rabinovitz, I., Cress, A. E. & Nagle, R. B., 1994, In : Prostate. 25, 2, p. 97-107 11 p.

Research output: Contribution to journalArticle

Laminin
Prostate
Carcinoma
Cell Line
laminin beta2
143 Citations (Scopus)

Differential expression of extracellular matrix molecules and the α6-integrins in the normal and neoplastic prostate

Knox, J. D., Cress, A. E., Clark, V., Manriquez, L., Affinito, K. S., Dalkin, B. L. & Nagle, R. B., Jul 1994, In : American Journal of Pathology. 145, 1, p. 167-174 8 p.

Research output: Contribution to journalArticle

Integrins
Extracellular Matrix
Prostate
Collagen Type VII
Basement Membrane
52 Citations (Scopus)

Histopathology of localized prostate cancer

Murphy, G. P., Busch, C., Abrahamsson, P. A., Epstein, J. I., McNeal, J. E., Miller, G. J., Mostofi, F. K., Nagle, R. B., Nordling, S., Parkinson, C. & Sesterhenn, I. A., 1994, In : Scandinavian Journal of Urology and Nephrology, Supplement. 162, p. 7-42 36 p.

Research output: Contribution to journalArticle

Prostatic Neoplasms
Neoplasms
Neoplasm Grading
Prostatectomy
Tumor Burden

Histopathology of localized prostate cancer. Consensus Conference on Diagnosis and Prognostic Parameters in Localized Prostate Cancer. Stockholm, Sweden, May 12-13, 1993.

Murphy, G. P., Busch, C., Abrahamsson, P. A., Epstein, J. I., McNeal, J. E., Miller, G. J., Mostofi, F. K., Nagle, R. B., Nordling, S. & Parkinson, C., 1994, In : Scandinavian Journal of Urology and Nephrology, Supplement. 162, p. 7-42 36 p.

Research output: Contribution to journalArticle

Sweden
Prostatic Neoplasms
Neoplasms
Seminal Vesicles
Prostatectomy
22 Citations (Scopus)

Immunohistochemical analysis of cathepsin D in prostate carcinoma.

Makar, R., Mason, A., Kittelson, J. M., Bowden, G. T., Cress, A. E. & Nagle, R. B., Sep 1994, In : Modern Pathology. 7, 7, p. 747-751 5 p.

Research output: Contribution to journalArticle

Cathepsin D
Prostate
Carcinoma
Staining and Labeling
Hyperplasia
2 Citations (Scopus)

Nephrotoxicity and uptake of 1-benzyl quinolinium in precision-cut rabbit renal cortical slices

Sheevers, H. V., Brendel, K., Wright, S., Nagle, R. B. & Gandolfi, A. J., 1994, In : Toxicology in Vitro. 8, 6, p. 1243-1251 9 p.

Research output: Contribution to journalArticle

Cations
Rabbits
Kidney
Toxicity
p-Aminohippuric Acid
41 Citations (Scopus)

The most promising surrogate endpoint biomarkers for screening candidate chemopreventive compounds for prostatic adenocarcinoma in short-term phase II clinical trials.

Bostwick, D. G., Burke, H. B., Wheeler, T. M., Chung, L. W., Bookstein, R., Pretlow, T. G., Nagle, R. B., Montironi, R., Lieber, M. M. & Veltri, R. W., 1994, In : Journal of cellular biochemistry. Supplement. 19, p. 283-289 7 p.

Research output: Contribution to journalArticle

Phase II Clinical Trials
Biomarkers
Screening
Adenocarcinoma
Chemoprevention
1993
102 Citations (Scopus)

Characterization of integrin subunits, cellular adhesion and tumorgenicity of four human prostate cell lines

Witkowski, C. M., Rabinovitz, I., Nagle, R. B., Affinito, K. S. D. & Cress, A. E., Nov 1993, In : Journal of Cancer Research and Clinical Oncology. 119, 11, p. 637-644 8 p.

Research output: Contribution to journalArticle

Integrins
Prostate
Cell Line
Laminin
Vitronectin
32 Citations (Scopus)

Ciprofloxacin-induced granulomatous interstitial nephritis and localized elastolysis

Lien, Y. H. H., Hansen, R., Kern, W. F., Bangert, J., Nagle, R. B., Ko, M. & Siskind, M. S., 1993, In : American Journal of Kidney Diseases. 22, 4, p. 598-602 5 p.

Research output: Contribution to journalArticle

Interstitial Nephritis
Ciprofloxacin
Steroids
Skin
Kidney
16 Citations (Scopus)

Endothelial transdifferentiated phenotype and cell-cycle kinetics of AIDS- associated Kaposi sarcoma cells

Way, D. L., Witte, M. H., Fiala, M., Ramirez, G., Nagle, R. B., Bernas, M. J., Dictor, M., Borgs, P. & Witte, C. L., 1993, In : Lymphology. 26, 2, p. 79-89 11 p.

Research output: Contribution to journalArticle

Ulex
Agglutinins
Kaposi's Sarcoma
Cell Cycle
Acquired Immunodeficiency Syndrome
180 Citations (Scopus)

Expression of the metalloproteinase matrilysin in DU-145 cells increases their invasive potential in severe combined immunodeficient mice

Powell, W. C., Knox, J. D., Navre, M., Grogan, T. M., Kittelson, J., Nagle, R. B. & Bowden, G. T., Jan 15 1993, In : Cancer Research. 53, 2, p. 417-422 6 p.

Research output: Contribution to journalArticle

Matrix Metalloproteinase 7
SCID Mice
Metalloproteases
Prostate
Matrix Metalloproteinase 2
23 Citations (Scopus)

Prostate tumor cell invasion: A comparison of orthotopic and ectopic models

Knox, J. D., Mack, C. F., Powell, W. C., Bowden, G. T. & Nagle, R. B., 1993, In : Invasion and Metastasis. 13, 6, p. 325-331 7 p.

Research output: Contribution to journalArticle

Diaphragm
Matrix Metalloproteinase 7
Prostate
Intraperitoneal Injections
Injections
116 Citations (Scopus)
Basement Membrane
Integrins
Prostate
Carcinoma
In Vitro Techniques