Raymond B Nagle

  • 11533 Citations
  • 58 h-Index
1968 …2020

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Research Output

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1997

Coordinated expression of matrilysin during TPA-induced apoptosis of LNCaP cells: Two parallel processes affected by TPA

Sundareshan, P., Koster, J. J., Nagle, R. B. & Bowden, G. T., Feb 26 1997, In : Cancer Letters. 113, 1-2, p. 17-24 8 p.

Research output: Contribution to journalArticle

8 Scopus citations

Diagnostic accuracy of an international static-imaging telepathology consultation service

Halliday, B. E., Bhahacharyya, A. K., Graham, A. R., Davis, J. R., Anne Leavitt, S., Nagle, R. B., McLaughlin, W. J., Rivas, R. A., Martinez, R., Krupinski, E. A. & Weinstein, R. S., Jan 1 1997, In : Human pathology. 28, 1, p. 17-21 5 p.

Research output: Contribution to journalArticle

119 Scopus citations

Differential expression of cytokeratin mRNA and protein in normal prostate, prostatic intraepithelial neoplasia, and invasive carcinoma

Yang, Y., Hao, J., Liu, X., Dalkin, B. & Nagle, R. B., Feb 21 1997, In : American Journal of Pathology. 150, 2, p. 693-704 12 p.

Research output: Contribution to journalArticle

45 Scopus citations

Effects of acute and chronic arsenic exposure of human-derived keratinocytes in an in vitro human skin equivalent system: A novel model of human arsenicism

Klimecki, W. T., Borchers, A. H., Egbert, R. E., Nagle, R. B., Carter, D. E. & Bowden, G. T., Feb 1 1997, In : Toxicology in Vitro. 11, 1-2, p. 89-98 10 p.

Research output: Contribution to journalArticle

21 Scopus citations

Interleukin-1β secreted from monocytic cells induces the expression of matrilysin in the prostatic cell line LNCaP

Klein, R. D., Borchers, A. H., Sundareshan, P., Bougelet, C., Berkman, M. R., Nagle, R. B. & Bowden, G. T., May 30 1997, In : Journal of Biological Chemistry. 272, 22, p. 14188-14192 5 p.

Research output: Contribution to journalArticle

26 Scopus citations

Pathologic and clinical findings in patients with cyclosporiasis and a description of intracellular parasite life-cycle stages

Ortega, Y. R., Nagle, R., Gilman, R. H., Watanabe, J., Miyagui, J., Quispe, H., Kanagusuku, P., Roxas, C. & Sterling, C. R., Jan 1 1997, In : Journal of Infectious Diseases. 176, 6, p. 1584-1589 6 p.

Research output: Contribution to journalArticle

Open Access
68 Scopus citations
1998
27 Scopus citations

Activation of gelatinase-tissue-inhibitors-of-metalloproteinase complexes by matrilysin

Von Bredow, D. C., Cress, A. E., Howard, E. W., Bowden, G. T. & Nagle, R. B., May 1 1998, In : Biochemical Journal. 331, 3, p. 965-972 8 p.

Research output: Contribution to journalArticle

48 Scopus citations

Extension of useful reagent shelf life beyond manufacturers' recommendations

Tubbs, R. R., Nagle, R., Leslie, K., Pettigrew, N. M., Said, J. W., Corwin, D. J., Rickert, R. R. & Roche, P. C., Dec 1 1998, In : Archives of Pathology and Laboratory Medicine. 122, 12, p. 1051-1052 2 p.

Research output: Contribution to journalArticle

7 Scopus citations

Synthetic matrix metalloproteinase inhibitor, BB-94, inhibits the invasion of neoplastic human prostate cells in a mouse model

Knox, J. D., Bretton, L., Lynch, T., Bowden, G. T. & Nagle, R. B., Jun 1 1998, In : Prostate. 35, 4, p. 248-254 7 p.

Research output: Contribution to journalArticle

27 Scopus citations
1999

EGF induces the expression of matrilysin in the human prostate adenocarcinoma cell line, LNCAP

Sundareshan, P., Nagle, R. B. & Bowden, G. T., Aug 1 1999, In : Prostate. 40, 3, p. 159-166 8 p.

Research output: Contribution to journalArticle

18 Scopus citations

Experimental induction of rhabdomyosarcoma in mice with fractionated doses of β-irradiation

Gupta, A., Andrews, K. L., McDaniel, K. M., Nagle, R. B. & Bowden, G. T., Jun 3 1999, In : Journal of Cancer Research and Clinical Oncology. 125, 5, p. 257-267 11 p.

Research output: Contribution to journalArticle

8 Scopus citations

Induction of melanoma in TPras transgenic mice

Powell, M. B., Gause, P. R., Hyman, P., Gregus, J., Lluria-Prevatt, M., Nagle, R. & Bowden, G. T., Sep 8 1999, In : Carcinogenesis. 20, 9, p. 1747-1753 7 p.

Research output: Contribution to journalArticle

74 Scopus citations
189 Scopus citations

Promatrilysin expression is induced by fibroblast growth factors in the prostatic carcinoma cell line LNCaP but not in normal primary prostate epithelial cells

Klein, R. D., Maliner-Jongewaard, M. S., Udayakumar, T. S., Boyd, J. L., Nagle, R. B. & Bowden, G. T., 1999, In : Prostate. 41, 4, p. 215-223 9 p.

Research output: Contribution to journalArticle

19 Scopus citations
2000

Altered surface expression and increased turnover of the α6β4 integrin in an undifferentiated carcinoma

Witkowski, C. M., Bowden, G. T., Nagle, R. B. & Cress, A. E., 2000, In : Carcinogenesis. 21, 2, p. 325-330 6 p.

Research output: Contribution to journalArticle

13 Scopus citations

Diagnostic frozen prostate sextant biopsies: An approach for preserving protein and RNA for additional studies

Scott, K. M., Fanta, P., Calaluce, R., Dalkin, B., Weinstein, R. S. & Nagle, R. B., Jan 1 2000, In : Prostate. 44, 4, p. 296-302 7 p.

Research output: Contribution to journalArticle

7 Scopus citations

Prognostic factors in colorectal cancer: College of American Pathologists consensus statement 1999

Compton, C. C., Fielding, L. P., Burgart, L. J., Conley, B., Cooper, H. S., Hamilton, S. R., Hammond, M. E. H., Henson, D. E., Hutter, R. V. P., Nagle, R. B., Nielsen, M. L., Sargent, D. J., Taylor, C. R., Welton, M. & Willett, C., Aug 15 2000, In : Archives of Pathology and Laboratory Medicine. 124, 7, p. 979-994 16 p.

Research output: Contribution to journalArticle

948 Scopus citations
2001

Aberrant expression of fibroblast growth factor receptor-1 in prostate epithelial cells allows induction of promatrilysin expression by fibroblast growth factors

Udayakumar, T. S., Klein, R. D., Maliner, M. S., Nagle, R. B. & Bowden, G. T., Jan 15 2001, In : International Journal of Cancer. 91, 2, p. 187-192 6 p.

Research output: Contribution to journalArticle

21 Scopus citations

Expression of the matrix metalloproteinase promatrilysin in coculture of prostate carcinoma cell lines

Stratton, M. S., Sirvent, H., Udayakumar, T. S., Nagle, R. B. & Bowden, G. T., Aug 22 2001, In : Prostate. 48, 3, p. 206-209 4 p.

Research output: Contribution to journalArticle

11 Scopus citations

Interleukin-1β-induced promatrilysin expression is mediated by NFκB-regulated synthesis of interleukin-6 in the prostate carcinoma cell line, LNCaP1

Maliner-Stratton, M. S., Klein, R. D., Udayakumar, T. S., Nagle, R. B. & Bowden, G. T., Jan 1 2001, In : Neoplasia. 3, 6, p. 509-520 12 p.

Research output: Contribution to journalArticle

21 Scopus citations

Investigation into the mechanism of the loss of laminin 5 (α3β3γ2) expression in prostate cancer

Hao, J., Jackson, L., Calaluce, R., McDaniel, K., Dalkin, B. L. & Nagle, R. B., 2001, In : American Journal of Pathology. 158, 3, p. 1129-1135 7 p.

Research output: Contribution to journalArticle

59 Scopus citations

New molecular approaches to tissue analysis

Nagle, R. B., Jan 1 2001, In : Journal of Histochemistry and Cytochemistry. 49, 8, p. 1063-1064 2 p.

Research output: Contribution to journalArticle

Open Access
11 Scopus citations

PEAZ-1: A new human prostate neoplastic epithelial cell line

Schmelz, M., Cress, A. E., Barrera, J., McDaniel, K. M., Davis, T. L., Fuchs, L., Dalkin, B. L. & Nagle, R. B., Jul 1 2001, In : Prostate. 48, 2, p. 79-92 14 p.

Research output: Contribution to journalArticle

8 Scopus citations

Signal transduction through the Ras/Erk pathway is essential for the mycoestrogen Zearalenone-induced cell-cycle progression in MCF-7 cells

Calaluce, R., Kunkel, M. W., Watts, G. S., Schmelz, M., Hao, J., Barrera, J., Gleason-Guzman, M., Isett, R., Fitchmun, M., Tim Bowden, G., Cress, A. E., Futscher, B. W. & Nagle, R. B., Mar 15 2001, In : Molecular Carcinogenesis. 30, 2, p. 88-98 11 p.

Research output: Contribution to journalArticle

98 Scopus citations

Unique expression pattern of the α6β4 integrin and laminin-5 in human prostate carcinoma

Davis, T. L., Cress, A. E., Dalkin, B. L. & Nagle, R. B., Feb 20 2001, In : Prostate. 46, 3, p. 240-248 9 p.

Research output: Contribution to journalArticle

75 Scopus citations
2002

Androgens block interleukin-1β-induced promatrilysin expression in prostate carcinoma cells

Stratton, M. S., Greenstein, B., Udayakumar, T. S., Nagle, R. B. & Bowden, G. T., Sep 15 2002, In : Prostate. 53, 1, p. 1-8 8 p.

Research output: Contribution to journalArticle

2 Scopus citations

Angiogenesis and neovascularization associated with extracellular matrix-modified porous implants

Kidd, K. R., Nagle, R. B. & Williams, S. K., Jan 1 2002, In : Journal of Biomedical Materials Research. 59, 2, p. 366-377 12 p.

Research output: Contribution to journalArticle

48 Scopus citations

Cell line-specific translation of two laminin 5 β3 chain isoforms

Hao, J., McDaniel, K., Weyer, C., Barrera, J. & Nagle, R. B., Jan 23 2002, In : Gene. 283, 1-2, p. 237-244 8 p.

Research output: Contribution to journalArticle

8 Scopus citations

Clinical laboratory assays for HER-2/neu amplification and overexpression: Quality assurance, standardization, and proficiency testing

Nagle, R. B., Tubbs, R. R., Roche, P. C., Hsi, E. D., Linden, M. D., Ormsby, A., Pettigrew, N. M., Rickert, R. R., Said, J. W., Bayer-Garner, I. B., Cooley, L. D., Brothman, A. R., Persons, D. L., Vance, G. H., Mascarello, J. T., Rao, K. W., Herrmann, M., Dewald, G. & Park, J. P., Jul 23 2002, In : Archives of Pathology and Laboratory Medicine. 126, 7, p. 803-808 6 p.

Research output: Contribution to journalArticle

89 Scopus citations

Culturing precision-cut human prostate slices as an in vitro model of prostate pathobiology

Parrish, A. R., Sallam, K., Nyman, D. W., Orozco, J., Cress, A. E., Dalkin, B. L., Nagle, R. B. & Gandolfi, A. J., Jun 18 2002, In : Cell Biology and Toxicology. 18, 3, p. 205-219 15 p.

Research output: Contribution to journalArticle

27 Scopus citations

Different phenotypes in human prostate cancer: α6 or α3 integrin in cell-extracellular adhesion sites

Schmelz, M., Cress, A. E., Scott, K. M., Bürgery, F., Cui, H., Sallam, K., McDaniel, K. M., Dalkin, B. L. & Nagle, R. B., May 28 2002, In : Neoplasia. 4, 3, p. 243-254 12 p.

Research output: Contribution to journalArticle

63 Scopus citations

Fibroblast growth factor-1 induced promatrilysin expression through the activation of extracellular-regulated kinases and STAT3

Udayakumar, T. S., Stratton, M. S., Nagle, R. B. & Bowden, G. T., Jan 29 2002, In : Neoplasia. 4, 1, p. 60-67 8 p.

Research output: Contribution to journalArticle

40 Scopus citations

Identification of differentially expressed genes in pancreatic cancer cells using cDNA microarray

Han, H., Bearss, D. J., Browne, L. W., Calaluce, R., Nagle, R. B. & Von Hoff, D. D., May 15 2002, In : Cancer Research. 62, 10, p. 2890-2896 7 p.

Research output: Contribution to journalArticle

332 Scopus citations
2003

Laminin Alpha-1, Alpha-3, and Alpha-5 chain expression in human prepubetal benign prostate glands and adult benign and malignant prostate glands

Brar, P. K., Dalkin, B. L., Weyer, C., Sallam, K., Virtanen, I. & Nagle, R. B., Apr 1 2003, In : Prostate. 55, 1, p. 65-70 6 p.

Research output: Contribution to journalArticle

25 Scopus citations

Membrane type-1-matrix metalloproteinase expressed by prostate carcinoma cells cleaves human laminin-5 β3 chain and induces cell migration

Udayakumar, T. S., Chen, M. L., Bair, E. L., Von Bredow, D. C., Cress, A. E., Nagle, R. B. & Bowden, G. T., May 1 2003, In : Cancer Research. 63, 9, p. 2292-2299 8 p.

Research output: Contribution to journalArticle

110 Scopus citations

Pharmacological inhibition of FGF receptor signaling inhibits LNCaP prostate tumor growth, promatrilysin, and PSA expression

Udayakumar, T. S., Bair, E. L., Nagle, R. B. & Bowden, G. T., Oct 2003, In : Molecular Carcinogenesis. 38, 2, p. 70-77 8 p.

Research output: Contribution to journalArticle

19 Scopus citations

Site-specific positive margins at radical prostatectomy: Assessing cancer-control benefits of wide excision of the neurovascular bundle on a side with cancer on biopsy

Park, E. L., Dalkin, B., Escobar, C. & Nagle, R. B., Feb 1 2003, In : BJU International. 91, 3, p. 219-222 4 p.

Research output: Contribution to journalArticle

28 Scopus citations
2004

Extracellular alpha 6 integrin cleavage by urokinase-type plasminogen activator in human prostate cancer

Demetriou, M. C., Pennington, M. E., Nagle, R. B. & Cress, A. E., Apr 1 2004, In : Experimental Cell Research. 294, 2, p. 550-558 9 p.

Research output: Contribution to journalArticle

45 Scopus citations

Fibroblast Growth Factor-I Transcriptionally Induces Membrane Type-I Matrix Metalloproteinase Expression in Prostate Carcinoma Cell Line

Udayakumar, T. S., Nagle, R. B. & Bowden, G. T., Jan 1 2004, In : Prostate. 58, 1, p. 66-75 10 p.

Research output: Contribution to journalArticle

33 Scopus citations

Identification of human polo-like kinase 1 as a potential therapeutic target in pancreatic cancer

Gray, P. J., Bearss, D. J., Han, H., Nagle, R., Tsao, M. S., Dean, N. & Von Hoff, D. D., May 1 2004, In : Molecular Cancer Therapeutics. 3, 5, p. 641-646 6 p.

Research output: Contribution to journalArticle

88 Scopus citations

Immunohistochemical comparison of vascular and sinusoidal adherens junctions in cavernosal endothelium

Wessells, H., King, S. H., Schmelz, M., Nagle, R. B. & Heimark, R. L., Jan 2004, In : Urology. 63, 1, p. 201-206 6 p.

Research output: Contribution to journalArticle

9 Scopus citations

Kimura disease with advanced renal damage with anti-tubular basement membrane antibody

Dixit, M. P., Scott, K. M., Bracamonte, E., Dixit, N. M., Schumacher, M. J., Hutter, J. & Nagle, R., Dec 1 2004, In : Pediatric Nephrology. 19, 12, p. 1404-1407 4 p.

Research output: Contribution to journalArticle

10 Scopus citations

Laminin-5 β3A expression in LNCaP human prostate carcinoma cells increases cell migration and tumorigenicity

Calaluce, R., Bearss, D. J., Barrera, J., Zhao, Y., Han, H., Beck, S. K., McDaniel, K. & Nagle, R. B., 2004, In : Neoplasia. 6, 5, p. 468-479 12 p.

Research output: Contribution to journalArticle

25 Scopus citations

Mutations in the G-quadruplex silencer element and their relationship to c-MYC overexpression, NM23 repression, and therapeutic rescue

Grand, C. L., Powell, T. J., Nagle, R. B., Bearss, D. J., Tye, D., Gleason-Guzman, M. & Hurley, L. H., Apr 20 2004, In : Proceedings of the National Academy of Sciences of the United States of America. 101, 16, p. 6140-6145 6 p.

Research output: Contribution to journalArticle

54 Scopus citations

Selenium and selenomethionine levels in prostate cancer patients

Nyman, D. W., Stratton, M. S., Kopplin, M. J., Dalkin, B. L., Nagle, R. B. & Gandolfi, A. J., Jan 1 2004, In : Cancer detection and prevention. 28, 1, p. 8-16 9 p.

Research output: Contribution to journalArticle

46 Scopus citations

The mitotic serine threonine kinase, Aurora-2, is a potential target for drug development in human pancreatic cancer

Rojanala, S., Han, H., Muñoz, R. M., Browne, W., Nagle, R., Von Hoff, D. D. & Bearss, D. J., Apr 2004, In : Molecular Cancer Therapeutics. 3, 4, p. 451-457 7 p.

Research output: Contribution to journalArticle

79 Scopus citations
2005

Aurora-A over-expression in high-grade PIN lesions and prostate cancer

Buschhorn, H. M. K., Klein, R. R., Chambers, S. M., Hardy, M. C., Green, S., Bearss, D. & Nagle, R. B., Sep 1 2005, In : Prostate. 64, 4, p. 341-346 6 p.

Research output: Contribution to journalArticle

51 Scopus citations

Membrane type 1 matrix metalloprotease cleaves laminin-10 and promotes cancer cell migration

Bair, E. L., Man, L. C., McDaniel, K., Sekiguchi, K., Cress, A. E., Nagle, R. B. & Bowden, G. T., Apr 2005, In : Neoplasia. 7, 4, p. 380-389 10 p.

Research output: Contribution to journalArticle

48 Scopus citations