Robert T Dorr

  • 9198 Citations
  • 49 h-Index
1976 …2016

Research output per year

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Research Output

  • 9198 Citations
  • 49 h-Index
  • 220 Article
  • 7 Letter
  • 7 Review article
  • 5 Comment/debate
1991

Chemoprotectants for cancer chemotherapy

Dorr, R. T., Feb 1991, In : Seminars in Oncology. 18, 1 SUPPL. 2, p. 48-58 11 p.

Research output: Contribution to journalArticle

54 Scopus citations

Comparison of cytotoxicity in heart cells and tumor cells exposed to DNA intercalating agents in vitro.

Dorr, R. T., Shipp, N. G. & Lee, K. M., Feb 1991, In : Anti-cancer drugs. 2, 1, p. 27-33 7 p.

Research output: Contribution to journalArticle

32 Scopus citations

Cutaneous ulceration due to contrast extravasation experimental assessment of injury and potential antidotes

Elam, E. A., Dorr, R. T., Lagel, K. E. & Pond, G. D., Jan 1991, In : Investigative Radiology. 26, 1, p. 13-16 4 p.

Research output: Contribution to journalArticle

38 Scopus citations

Induction of Skin Tanning by Subcutaneous Administration of a Potent Synthetic Melanotropin

Levine, N., Sheftel, S. N., Eytan, T., Dorr, R. T., Hadley, M. E., Weinrach, J. C., Ertl, G. A., Toth, K., McGee, D. L. & Hruby, V. J., Nov 20 1991, In : JAMA: The Journal of the American Medical Association. 266, 19, p. 2730-2736 7 p.

Research output: Contribution to journalArticle

188 Scopus citations

In vitro cytotoxicity against fresh human tumors and P388 leukemia predicts the differential in vivo activity of a series of anthracene anticancer drugs.

Alberts, D. S., Dorr, R. T., Wunz, T. P., Remers, W. A., Einspahr, J., Liu, R. & Salmon, S. E., Feb 1991, In : Anti-cancer drugs. 2, 1, p. 69-77 9 p.

Research output: Contribution to journalArticle

3 Scopus citations

Lack of ranitidine effects on cyclophosphamide bon marrow toxicity or metabolism: A placebo-controlled clinical trial

Alberts, D. S., Mason-liddil, N., Plezia, P. M., Roe, D. J., Dorr, R. T., Struck, R. F. & Phillips, J. G., Apr 4 1991, In : Journal of the National Cancer Institute. 83, 23, p. 1739-1743 5 p.

Research output: Contribution to journalArticle

11 Scopus citations

Modulation of mitomycin C-induced multidrug resistance in vitro

Dorr, R. T. & Liddil, J. D., Jul 1 1991, In : Cancer Chemotherapy And Pharmacology. 27, 4, p. 290-294 5 p.

Research output: Contribution to journalArticle

16 Scopus citations

Structure-Activity Relationships for Mitomycin C and Mitomycin A Analogues

Kunz, K. R., Iyengar, B. S., Reiners, W. A., Dorr, R. T. & Alberts, D. S., Jul 1 1991, In : Journal of Medicinal Chemistry. 34, 7, p. 2281-2286 6 p.

Research output: Contribution to journalArticle

51 Scopus citations

Structure-Activity Studies of Antitumor Agents Based on Pyrrolo[1,2-a]benzimidazoles: New Reductive Alkylating DNA Cleaving Agents

Islam, I., Skibo, E. B., Dorr, R. T. & Alberts, D. S., Oct 1 1991, In : Journal of Medicinal Chemistry. 34, 10, p. 2954-2961 8 p.

Research output: Contribution to journalArticle

88 Scopus citations
1990

Alkylation of DNA by C-10 of 2,7-Diaminomitosene

Iyengar, B. S., Remers, W. A., Dorr, R. T. & Shipp, N. G., Jan 1990, In : Journal of Medicinal Chemistry. 33, 1, p. 253-257 5 p.

Research output: Contribution to journalArticle

24 Scopus citations

Antidotes to vesicant chemotherapy extravasations

Dorr, R. T., Mar 1990, In : Blood Reviews. 4, 1, p. 41-60 20 p.

Research output: Contribution to journalArticle

118 Scopus citations

Mitomycin, ifosfamide, and mesna in the treatment of lung cancer

Dorr, R. T., Jan 1 1990, In : Seminars in Oncology. 17, 4 SUPPL. 7, p. 2-5 4 p.

Research output: Contribution to journalArticle

Recent advances in the management of lung and breast cancer: Introduction

Alberts, D. S. & Dorr, R. T., Jan 1 1990, In : Seminars in Oncology. 17, 4 SUPPL. 7, 1 p.

Research output: Contribution to journalComment/debate

The clinical relevance of multidrug resistance

Bellamy, W. T., Dalton, W. S. & Dorr, R. T., Jan 1 1990, In : Cancer Investigation. 8, 5, p. 547-562 16 p.

Research output: Contribution to journalArticle

61 Scopus citations
1989

Alpha‐globulins suppress human leukocyte tumor necrosis factor secretion

Scuderi, P., Dorr, R. T., Liddil, J. D., Finley, P. R., Meltzer, P., Raitano, A. B. & Rybski, J., May 1989, In : European Journal of Immunology. 19, 5, p. 939-942 4 p.

Research output: Contribution to journalArticle

44 Scopus citations

Antitumor Activity and Murine Pharmacokinetics of Parenteral Acronycine

Dorr, R. T., Liddil, J. D., Von Hoff, D. D., Soble, M. & Osborne, C. K., Jan 15 1989, In : Cancer Research. 49, 2, p. 340-344 5 p.

Research output: Contribution to journalArticle

81 Scopus citations

Association of Lysosomal Activity with Sensitivity and Resistance to Tumor Necrosis Factor in Murine L929 Cells

Liddil, J. D., Dorr, R. T. & Scuderi, P., Mar 15 1989, In : Cancer Research. 49, 10, p. 2722-2728 7 p.

Research output: Contribution to journalArticle

34 Scopus citations

Effect of interferon, interleukin-2 and tumor necrosis factor on myocardial cell viability and doxorubicin cardiotoxicity in vitro

Dorr, R. T. & Shipp, N. G., Jan 1 1989, In : Immunopharmacology. 18, 1, p. 31-38 8 p.

Research output: Contribution to journalArticle

12 Scopus citations

H2-Antagonists and carmustine

Dorr, R. T. & Soble, M. J., Feb 1 1989, In : Journal of Cancer Research and Clinical Oncology. 115, 1, p. 41-46 6 p.

Research output: Contribution to journalArticle

3 Scopus citations

High levels of doxorubicin in the tissues of a patient experiencing extravasation during a 4‐day infusion

Dorr, R. T., Dordal, M. S., Koenig, L. M., Taylor, C. W. & McCloskey, T. M., Dec 15 1989, In : Cancer. 64, 12, p. 2462-2464 3 p.

Research output: Contribution to journalArticle

15 Scopus citations

Interaction between cisplatin and mesna in mice

Dorr, R. T. & Lagel, K., Nov 1 1989, In : Journal of Cancer Research and Clinical Oncology. 115, 6, p. 604-605 2 p.

Research output: Contribution to journalArticle

11 Scopus citations

Role of glutathione and its associated enzymes in multidrug-resistant human myeloma cells

Bellamy, W. T., Dalton, W. S., Meltzer, P. & Dorr, R. T., Mar 1 1989, In : Biochemical Pharmacology. 38, 5, p. 787-793 7 p.

Research output: Contribution to journalArticle

31 Scopus citations
1988

Cimetidine enhances cisplatin toxicity in mice

Dorr, R. T. & Soble, M. J., Feb 1 1988, In : Journal of Cancer Research and Clinical Oncology. 114, 1, p. 1-2 2 p.

Research output: Contribution to journalArticle

7 Scopus citations

Daily variation in non-protein sulfhydryl levels of human bone marrow

Bellamy, W. T., Alberts, D. S. & Door, R. T., Nov 1988, In : European Journal of Cancer and Clinical Oncology. 24, 11, p. 1759-1762 4 p.

Research output: Contribution to journalArticle

7 Scopus citations

Development of a parenteral formulation for the anti-tumour agent acronycine

Dorr, R. T. & Liddil, J. D., Jan 1 1988, In : Journal of Drug Development. 1, 1, p. 31-39 9 p.

Research output: Contribution to journalArticle

26 Scopus citations

Direct Relation of DNA Lesions in Multidrug-resistant Human Myeloma Cells to Intracellular Doxorubicin Concentration

Bellamy, W. T., Dorr, R. T., Dalton, W. S. & Alberts, D. S., Nov 1988, In : Cancer Research. 48, 22, p. 6360-6364 5 p.

Research output: Contribution to journalArticle

25 Scopus citations

Efficacy of sodium thiosulfate as a local antidote to mechlorethamine skin toxicity in the mouse

Dorr, R. T., Soble, M. & Alberts, D. S., Oct 1 1988, In : Cancer Chemotherapy And Pharmacology. 22, 4, p. 299-302 4 p.

Research output: Contribution to journalArticle

29 Scopus citations

In Vitro Rat Myocyte Cardiotoxicity Model for Antitumor Antibiotics Using Adenosine Triphosphate/Protein Ratios

Dorr, R. T., Bozak, K. A., Shipp, N. G., Hendrix, M., Alberts, D. S. & Ahmann, F., Sep 1988, In : Cancer Research. 48, 18, p. 5222-5227 6 p.

Research output: Contribution to journalArticle

31 Scopus citations
4 Scopus citations

Mitomycin C toxicity and pharmacokinetics in mice given sulfur nucleophiles

Dorr, R. T., Alberts, D. S. & Liddil, J. D., Jan 1 1988, In : Anticancer research. 8, 4, p. 733-738 6 p.

Research output: Contribution to journalArticle

3 Scopus citations

New findings in the pharmacokinetic, metabolic, and drug-resistance aspects of mitomycin C

Dorr, R. T., Jun 1988, In : Seminars in Oncology. 15, 3 SUPPL. 4, p. 32-41 10 p.

Research output: Contribution to journalArticle

61 Scopus citations

Nucleotide Derivatives of 2,7-Diaminomitosene

Iyengar, B. S., Dorr, R. T., Remers, W. A. & Kowal, C. D., Sep 1 1988, In : Journal of Medicinal Chemistry. 31, 8, p. 1579-1585 7 p.

Research output: Contribution to journalArticle

12 Scopus citations

Phase I-II Trial of Interferon-α2b by Continuous Subcutaneous Infusion over 28 Days

Dorr, R. T., Salmon, S. E., Robertone, A. & Bonnem, E., Dec 1988, In : Journal of Interferon Research. 8, 6, p. 717-725 9 p.

Research output: Contribution to journalArticle

14 Scopus citations
3 Scopus citations

Toxicologic studies of a superpotent α-melanotropin, [Nle4, D-Phe7]α-MSH

Dorr, R. T., Dawson, B. V., Al-Obeidi, F., Hadley, M. E., Levine, N. & Hruby, V. J., Dec 1 1988, In : Investigational New Drugs. 6, 4, p. 251-258 8 p.

Research output: Contribution to journalArticle

22 Scopus citations

Transdermal delivery of a melanotropic peptide hormone analogue

Dawson, B. V., Hadley, M. E., Kreutzfeld, K., Dorr, R. T., Hruby, V. J., Al-Obeidi, F. & Don, S., 1988, In : Life Sciences. 43, 14, p. 1111-1117 7 p.

Research output: Contribution to journalArticle

21 Scopus citations

Verapamil Reversal of Doxorubicin Resistance in Multidrug-resistant Human Myeloma Cells and Association with Drug Accumulation and DNA Damage

Bellamy, W. T., Dalton, W. S., Kailey, J. M., Gleason, M. C., McCloskey, T. M., Dorr, R. T. & Alberts, D., Nov 1988, In : Cancer Research. 48, 22, p. 6365-6370 6 p.

Research output: Contribution to journalArticle

93 Scopus citations
1987

Cisplatin nephrotoxicity: In vitro studies with precision-cut rabbit renal cortical slices

Phelps, J. S., Gandolfi, A. J., Brendel, K. & Dorr, R. T., Sep 30 1987, In : Toxicology and Applied Pharmacology. 90, 3, p. 501-512 12 p.

Research output: Contribution to journalArticle

48 Scopus citations

Dose-dependent skin ulcers in mice treated with DNA binding antitumor antibiotics

Soble, M. J., Dorr, R. T., Plezia, P. & Breckenridge, S., Aug 1 1987, In : Cancer Chemotherapy And Pharmacology. 20, 1, p. 33-36 4 p.

Research output: Contribution to journalArticle

13 Scopus citations

Experimental dacarbazine antitumor activity and skin toxicity in relation to light exposure and pharmacologic antidotes

Dorr, R. T., Alberts, D. S., Einspahr, J., Mason-Liddil, N. & Soble, M., Jun 5 1987, In : Cancer Treatment Reports. 71, 3, p. 267-272 6 p.

Research output: Contribution to journalArticle

5 Scopus citations

High incidence of local venous reactions to esorubicin

Lee, K. M., Dorr, R. T. & Robertone, A., Mar 1 1987, In : Investigational New Drugs. 5, 1, p. 31-35 5 p.

Research output: Contribution to journalArticle

4 Scopus citations
9 Scopus citations

Mitomycin C resistant L1210 leukemia cells: Association with pleiotropic drug resistance

Dorr, R. T., Liddil, J. D., Trent, J. M. & Dalton, W. S., Oct 1 1987, In : Biochemical Pharmacology. 36, 19, p. 3115-3120 6 p.

Research output: Contribution to journalArticle

48 Scopus citations

New Antitumor Agents Containing the Anthracene Nucleus

Wunz, T. P., Dorr, R. T., Alberts, D. S., Tunget, C. L., Einspahr, J., Milton, S. & Remers, W. A., Aug 1 1987, In : Journal of Medicinal Chemistry. 30, 8, p. 1313-1321 9 p.

Research output: Contribution to journalArticle

36 Scopus citations
5 Scopus citations

Schedule-Dependent Toxicity of Tumor Necrosis Factor in Rodents

Liddil, J. D. & Dorr, R. T., Jan 1 1987, In : Cancer Drug Delivery. 4, 3, p. 159-167 9 p.

Research output: Contribution to journalArticle

3 Scopus citations

VII. Topical application of a melanotropic peptide induces systemic follicular melanogenesis

Hadley, M. E., Wood, S. H., Lemus-Wilson, A. M., Dawson, B. V., Levine, N., Dorr, R. T. & Hruby, V. J., May 11 1987, In : Life Sciences. 40, 19, p. 1889-1895 7 p.

Research output: Contribution to journalArticle

15 Scopus citations
1986

Controlled Studies of a New Microprocessor-Based Portable Infusion Pump

Dorr, R. T., Salmon, S. E., Marsh, M. E. & Robertone, A., Jan 1 1986, In : Cancer Drug Delivery. 3, 2, p. 139-146 8 p.

Research output: Contribution to journalArticle

2 Scopus citations

Cytotoxic effects of glutathione synthesis inhibition by L-buthionine-(SR)-sulfoximine on human and murine tumor cells

Dorr, R. T., Liddil, J. D. & Soble, M. J., Dec 1 1986, In : Investigational New Drugs. 4, 4, p. 305-313 9 p.

Research output: Contribution to journalArticle

25 Scopus citations

Interaction of cimetidine but not ranitidine with cyclophosphamide in mice1

Dorr, R. T., Alberts, D. S. & Soble, M. J., Apr 1 1986, In : Cancer Research. 46, p. 1795-1799 5 p.

Research output: Contribution to journalArticle

24 Scopus citations