Projects per year
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- 2 Similar Profiles
Glycopeptides
Medicine & Life Sciences
Schiff Bases
Chemical Compounds
Enkephalins
Medicine & Life Sciences
Opioid Analgesics
Medicine & Life Sciences
Glycosylation
Medicine & Life Sciences
Blood-Brain Barrier
Medicine & Life Sciences
Glycosides
Medicine & Life Sciences
Peptides
Medicine & Life Sciences
Network
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Projects 1987 2020
PACAP/VIP Glycopeptide Agonists as Neuroprotective Therapies for Parkinson's Disease
9/30/15 → 6/30/20
Project: Research project
Pituitary Adenylate Cyclase-Activating Polypeptide
Glycopeptides
Vasoactive Intestinal Peptide
Parkinson Disease
Intercellular Signaling Peptides and Proteins
Blood-Brain Barrier
Glycopeptides
Peptides
Endorphins
Glycosylation
Research Output 1982 2019
- 2797 Citations
- 28 h-Index
- 77 Article
A novel angiotensin-(1-7) glycosylated MAs receptor agonist for treating vascular cognitive impairment and inflammation-related memory dysfunction
Hay, M., Polt, R. L., Heien, M. L., Vanderah, T. W., Largent-Milnes, T. M., Rodgers, K., Falk, T., Bartlett, M. J., Doyle, K. & Konhilas, J., Apr 1 2019, In : Journal of Pharmacology and Experimental Therapeutics. p. 9-25 17 p.Research output: Contribution to journal › Article
Blood Vessels
Dementia
Inflammation
Heart Failure
Peptides
Biodegradability and toxicity of monorhamnolipid biosurfactant diastereomers
Hogan, D. E., Tian, F., Malm, S. W., Olivares, C., Palos Pacheco, R., Simonich, M. T., Hunjan, A. S., Tanguay, R. L., Klimecki, W., Polt, R. L., Pemberton, J. E., Curry, J. E. & Maier, R. M., Feb 15 2019, In : Journal of Hazardous Materials. 364, p. 600-607 8 p.Research output: Contribution to journal › Article
Biodegradability
Zebrafish
Toxicity
Assays
assay
An update on sphingosine-1-phosphate receptor 1 modulators
Marciniak, A., Camp, S. M., Garcia, J. GN. & Polt, R. L., Jan 1 2018, (Accepted/In press) In : Bioorganic and Medicinal Chemistry Letters.Research output: Contribution to journal › Article
Lysosphingolipid Receptors
Sphingolipids
Modulators
Multiple Sclerosis
Mouth Diseases
The combination of the opioid glycopeptide MMP-2200 and a NMDA receptor antagonist reduced L-DOPA-induced dyskinesia and MMP-2200 by itself reduced dopamine receptor 2-like agonist-induced dyskinesia
Flores, A. J., Bartlett, M. J., Root, B. K., Parent, K. L., Heien, M. L., Porreca, F., Polt, R. L., Sherman, S. J. & Falk, T., Oct 1 2018, In : Neuropharmacology. 141, p. 260-271 12 p.Research output: Contribution to journal › Article
Glycopeptides
Dyskinesias
Dopamine Receptors
N-Methyl-D-Aspartate Receptors
Opioid Analgesics
12
Citations
(Scopus)
Synthesis and Characterization of Four Diastereomers of Monorhamnolipids
Palos Pacheco, R., Eismin, R. J., Coss, C. S., Wang, H., Maier, R. M., Polt, R. L. & Pemberton, J. E., Apr 12 2017, In : Journal of the American Chemical Society. 139, 14, p. 5125-5132 8 p.Research output: Contribution to journal › Article
Critical micelle concentration
Micelles
Surface Tension
Biodegradability
Glycolipids