• 406 Citations
  • 11 h-Index
20052017
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Fingerprint Dive into the research topics where Ruben S Vardanyan is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

Opioid Analgesics Chemical Compounds
Fentanyl Medicine & Life Sciences
Opioid Receptors Chemical Compounds
Ligands Medicine & Life Sciences
Enkephalins Chemical Compounds
delta Opioid Receptor Medicine & Life Sciences
Opioid Peptides Medicine & Life Sciences
Derivatives Chemical Compounds

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Research Output 2005 2017

  • 406 Citations
  • 11 h-Index
  • 20 Article
  • 2 Book

Piperidine-based drug discovery

Vardanyan, R. S., Jun 14 2017, Elsevier. 347 p.

Research output: Book/ReportBook

Derivatives
Scaffolds
Pharmaceutical Preparations
Heterocyclic Compounds
Histamine Antagonists
2 Citations (Scopus)

Synthesis and Investigation of Mixed μ-Opioid and δ-Opioid Agonists as Possible Bivalent Ligands for Treatment of Pain

Vardanyan, R. S., Cain, J. P., Haghighi, S. M., Kumirov, V. K., Mcintosh, M. I., Sandweiss, A. J., Porreca, F. & Hruby, V. J., 2016, (Accepted/In press) In : Journal of Heterocyclic Chemistry.

Research output: Contribution to journalArticle

Opioid Receptors
Opioid Analgesics
Analgesics
Ligands
Enkephalins
5 Citations (Scopus)

Development and characterisation of novel fentanyl-delta opioid receptor antagonist based bivalent ligands

Bird, M. F., Vardanyan, R. S., Hruby, V. J., Caló, G., Guerrini, R., Salvadori, S., Trapella, C., McDonald, J., Rowbotham, D. J. & Lambert, D. G., Apr 1 2015, In : British Journal of Anaesthesia. 114, 4, p. 646-656 11 p.

Research output: Contribution to journalArticle

delta Opioid Receptor
Opioid Peptides
Narcotic Antagonists
Fentanyl
Ligands
82 Citations (Scopus)
Fentanyl
Neurokinin-1 Receptors
delta Opioid Receptor
mu Opioid Receptor
Structure-Activity Relationship
1 Citation (Scopus)

Chiral effect of a Phe residue in position 3 of the Dmt1-l (or d)-Tic2 analogues on opioid functional activities

Lee, Y. S., Qu, H., Davis, P., Ma, S. W., Vardanyan, R. S., Lai, J., Porreca, F. & Hruby, V. J., Jul 11 2013, In : ACS Medicinal Chemistry Letters. 4, 7, p. 656-659 4 p.

Research output: Contribution to journalArticle

Chirality
Opioid Receptors
Opioid Analgesics
Structure-Activity Relationship
Ligands