• 10873 Citations
  • 55 h-Index
1970 …2019

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Article
2019

Effect of pH and Ionic Strength on the Solubility of Quinoline: Back-to-Basics

Carvajal, M. T. & Yalkowsky, S. H., Apr 1 2019, In : AAPS PharmSciTech. 20, 3, 124.

Research output: Contribution to journalArticle

1 Scopus citations
2018

A rule of unity for human intestinal absorption 3: Application to pharmaceuticals

Patel, R. B. & Yalkowsky, S. H., Feb 1 2018, In : Biopharmaceutics and Drug Disposition. 39, 2, p. 67-74 8 p.

Research output: Contribution to journalArticle

Estimating the Physicochemical Properties of Polysubstituted Aromatic Compounds Using UPPER

Alantary, D. & Yalkowsky, S. H., Jan 1 2018, In : Journal of Pharmaceutical Sciences. 107, 1, p. 297-306 10 p.

Research output: Contribution to journalArticle

1 Scopus citations

Estimation of Melting Points of Organics

Yalkowsky, S. H. & Alantary, D., Jan 1 2018, (Accepted/In press) In : Journal of Pharmaceutical Sciences.

Research output: Contribution to journalArticle

6 Scopus citations

Overcoming the Challenges of Low Drug Solubility in the Intravenous Formulation of Solithromycin

Evans, D., Yalkowsky, S. H., Wu, S., Pereira, D. & Fernandes, P., Jan 1 2018, In : Journal of Pharmaceutical Sciences. 107, 1, p. 412-418 7 p.

Research output: Contribution to journalArticle

1 Scopus citations
2017
3 Scopus citations
2016

Calculating the Solubilities of Drugs and Drug-Like Compounds in Octanol

Alantary, D. & Yalkowsky, S. H., Sep 1 2016, In : Journal of Pharmaceutical Sciences. 105, 9, p. 2770-2773 4 p.

Research output: Contribution to journalArticle

2 Scopus citations

Imaging of in vitro parenteral drug precipitation

Evans, D. C., Kudenov, M. W., Sassenrath, K. C., Dereniak, E. L. & Yalkowsky, S. H., Oct 15 2016, In : International Journal of Pharmaceutics. 512, 1, p. 219-223 5 p.

Research output: Contribution to journalArticle

2 Scopus citations
2015

Application of the henderson-hasselbalch equation to solubility determination: NSC-639829 case study

Yalkowsky, S. H., Patel, R. & Al-Antary, D., Dec 1 2015, In : ADMET and DMPK. 3, 4, p. 359-362 4 p.

Research output: Contribution to journalArticle

A rule of unity for human intestinal absorption 2: Application to drugs that are marketed as salts

Patel, R. B., Admire, B. & Yalkowsky, S. H., Jan 1 2015, In : Current Drug Delivery. 12, 2, p. 238-243 6 p.

Research output: Contribution to journalArticle

1 Scopus citations

Estimating the physicochemical properties of polyhalogenated aromatic and aliphatic compounds using UPPER: Part 1. Boiling point and melting point

Admire, B., Lian, B. & Yalkowsky, S. H., Jan 1 2015, In : Chemosphere. 119, p. 1436-1440 5 p.

Research output: Contribution to journalArticle

10 Scopus citations
10 Scopus citations
2014

Unified physicochemical property estimation relationships (UPPER)

Lian, B. & Yalkowsky, S. H., Sep 2014, In : Journal of pharmaceutical sciences. 103, 9, p. 2710-2723 14 p.

Research output: Contribution to journalArticle

8 Scopus citations
2013

Predicting the octanol solubility of organic compounds

Admire, B. & Yalkowsky, S. H., Jul 2013, In : Journal of pharmaceutical sciences. 102, 7, p. 2112-2119 8 p.

Research output: Contribution to journalArticle

11 Scopus citations
2012

Molecular geometry and boiling related thermodynamic properties

Lian, B. & Yalkowsky, S. H., Nov 1 2012, In : Journal of Chemical Thermodynamics. 54, p. 250-253 4 p.

Research output: Contribution to journalArticle

6 Scopus citations

Molecular geometry and melting point related properties

Lian, B. & Yalkowsky, S. H., Dec 26 2012, In : Industrial and Engineering Chemistry Research. 51, 51, p. 16750-16754 5 p.

Research output: Contribution to journalArticle

10 Scopus citations

Perspective on improving passive human intestinal absorption

Yalkowsky, S. H., Sep 2012, In : Journal of pharmaceutical sciences. 101, 9, p. 3047-3050 4 p.

Research output: Contribution to journalArticle

12 Scopus citations

Preformulation study of NSC-726796

Guo, D., Cain, J. P., O'Connell, S., Gardner, E. R., Pisle, S., Figg, W. D., Tabibi, S. E. & Yalkowsky, S. H., Jun 1 2012, In : AAPS PharmSciTech. 13, 2, p. 661-673 13 p.

Research output: Contribution to journalArticle

1 Scopus citations
2011

A simplified approach to predict the heat of melting for organic compounds

Lian, B. & Yalkowsky, S. H., Oct 15 2011, In : Chemometrics and Intelligent Laboratory Systems. 108, 2, p. 150-153 4 p.

Research output: Contribution to journalArticle

9 Scopus citations

A simplified prediction of entropy of melting for energetic compounds

Evans, D. C. & Yalkowsky, S. H., Apr 15 2011, In : Fluid Phase Equilibria. 303, 1, p. 10-14 5 p.

Research output: Contribution to journalArticle

9 Scopus citations
2010

Prediction of aqueous solubility from SCRATCH

Jain, P. & Yalkowsky, S. H., Jan 29 2010, In : International Journal of Pharmaceutics. 385, 1-2, p. 1-5 5 p.

Research output: Contribution to journalArticle

14 Scopus citations

Rapamycin pharmacokinetic and pharmacodynamic relationships in osteosarcoma: A comparative oncology study in dogs

Paoloni, M. C., Mazcko, C., Fox, E., Fan, T., Lana, S., Kisseberth, W., Vail, D. M., Nuckolls, K., Osborne, T., Yalkowsy, S., Gustafson, D., Yu, Y., Cao, L. & Khanna, C., Aug 9 2010, In : PloS one. 5, 6, e11013.

Research output: Contribution to journalArticle

Open Access
38 Scopus citations

Stability of 5-fluoro-2′-deoxycytidine and tetrahydrouridine in combination

Guo, D., Myrdal, P. B., Karlage, K. L., O'Connell, S. P., Wissinger, T. J., Tabibi, S. E. & Yalkowsky, S. H., Mar 1 2010, In : AAPS PharmSciTech. 11, 1, p. 247-252 6 p.

Research output: Contribution to journalArticle

12 Scopus citations
2009

2-[N-(2,4-Difluoro-phen-yl)carbamo-yl]-3,4,5,6-tetra-fluoro-benzoic acid

Guo, D., Nichol, G. S., Cain, J. P. & Yalkowsky, S. H., Nov 18 2009, In : Acta Crystallographica Section E: Structure Reports Online. 65, 11, p. o2644

Research output: Contribution to journalArticle

2 Scopus citations

An interesting relationship between drug absorption and melting point

Chu, K. A. & Yalkowsky, S. H., May 21 2009, In : International Journal of Pharmaceutics. 373, 1-2, p. 24-40 17 p.

Research output: Contribution to journalArticle

36 Scopus citations

Estimation of the molar heat capacity change on melting of organic compounds

Wu, M. & Yalkowsky, S., Jan 21 2009, In : Industrial and Engineering Chemistry Research. 48, 2, p. 1063-1066 4 p.

Research output: Contribution to journalArticle

12 Scopus citations

Predicting aqueous solubility: The role of crystallinity

Chu, K. A. & Yalkowsky, S. H., Dec 2009, In : Current Drug Metabolism. 10, 10, p. 1184-1191 8 p.

Research output: Contribution to journalArticle

10 Scopus citations

Preformulation and pharmacokinetic studies on antalarmin: A novel stress inhibitor

Sanghvi, R., Mogalian, E., Machatha, S. G., Narazaki, R., Karlage, K. L., Jain, P., Tabibi, S. E., Glaze, E., Myrdal, P. B. & Yalkowsky, S. H., Jan 2009, In : Journal of pharmaceutical sciences. 98, 1, p. 205-214 10 p.

Research output: Contribution to journalArticle

15 Scopus citations
2008

Comparison of aqueous solubility estimation from AQUAFAC and the GSE

Jain, P., Sepassi, K. & Yalkowsky, S. H., Aug 6 2008, In : International Journal of Pharmaceutics. 360, 1-2, p. 122-147 26 p.

Research output: Contribution to journalArticle

11 Scopus citations

Formulation and in vivo evaluation of chlorpropham (CIPC) oral formulations

Kuehl, P. J., Brenner, T., Jain, P. K., Karlage, K., Sepassi, K., Yang, G., Mayersohn, M., Yalkowsky, S. H. & Myrdal, P. B., Dec 2008, In : Journal of pharmaceutical sciences. 97, 12, p. 5222-5228 7 p.

Research output: Contribution to journalArticle

2 Scopus citations

Solubility improvement of drugs using N-methyl pyrrolidone

Sanghvi, R., Narazaki, R., Machatha, S. G. & Yalkowsky, S. H., Jun 1 2008, In : AAPS PharmSciTech. 9, 2, p. 366-376 11 p.

Research output: Contribution to journalArticle

77 Scopus citations
2007

Comparison of two methods for estimation of melting points of organic compounds

Jain, A. & Yalkowsky, S. H., Apr 11 2007, In : Industrial and Engineering Chemistry Research. 46, 8, p. 2589-2592 4 p.

Research output: Contribution to journalArticle

21 Scopus citations

Degradation kinetics and mechanism of RH1, a new anti-tumor agent: A technical note

Jain, N., Machatha, S. G., Tabibi, S. E. & Yalkowsky, S. H., Mar 2 2007, In : AAPS PharmSciTech. 8, 1, 16.

Research output: Contribution to journalArticle

Estimation of drug precipitation upon dilution of pH-controlled formulations

Narazaki, R., Sanghvi, R. & Yalkowsky, S. H., Jul 1 2007, In : Molecular Pharmaceutics. 4, 4, p. 550-555 6 p.

Research output: Contribution to journalArticle

11 Scopus citations

Estimation of drug precipitation upon dilution of pH-cosolvent solubilized formulations

Narazaki, R., Sanghvi, R. & Yalkowsky, S. H., Aug 1 2007, In : Chemical and Pharmaceutical Bulletin. 55, 8, p. 1203-1206 4 p.

Research output: Contribution to journalArticle

4 Scopus citations

Simplified estimation of the octanol-air partition coefficient

Sepassi, K. & Yalkowsky, S. H., Mar 28 2007, In : Industrial and Engineering Chemistry Research. 46, 7, p. 2220-2223 4 p.

Research output: Contribution to journalArticle

4 Scopus citations

Solubilization of poorly soluble compounds using 2-pyrrolidone

Jain, P. & Yalkowsky, S. H., Sep 5 2007, In : International Journal of Pharmaceutics. 342, 1-2, p. 1-5 5 p.

Research output: Contribution to journalArticle

30 Scopus citations

Stacking complexation by nicotinamide: A useful way of enhancing drug solubility

Sanghvi, R., Evans, D. & Yalkowsky, S. H., May 4 2007, In : International Journal of Pharmaceutics. 336, 1, p. 35-41 7 p.

Research output: Contribution to journalArticle

64 Scopus citations
2006

A 'rule of unity' for human intestinal absorption

Yalkowsky, S. H., Johnson, J. L. H., Sanghvi, T. & Machatha, S. G., Oct 1 2006, In : Pharmaceutical Research. 23, 10, p. 2475-2481 7 p.

Research output: Contribution to journalArticle

23 Scopus citations

Estimating pure-component vapor pressures of complex organic molecules: Part II

Sepassi, K., Myrdal, P. B. & Yalkowsky, S. H., Dec 6 2006, In : Industrial and Engineering Chemistry Research. 45, 25, p. 8744-8747 4 p.

Research output: Contribution to journalArticle

11 Scopus citations

Estimation of heat capacity of boiling of organic compounds

Sanghvi, R. & Yalkowsky, S. H., Jan 4 2006, In : Industrial and Engineering Chemistry Research. 45, 1, p. 451-453 3 p.

Research output: Contribution to journalArticle

2 Scopus citations

Estimation of melting points of organic compounds-II

Jain, A. & Yalkowsky, S. H., Dec 2006, In : Journal of pharmaceutical sciences. 95, 12, p. 2562-2618 57 p.

Research output: Contribution to journalArticle

71 Scopus citations

Estimation of the aqueous solubility of weak electrolytes

Jain, N., Yang, G., Machatha, S. G. & Yalkowsky, S. H., Aug 17 2006, In : International Journal of Pharmaceutics. 319, 1-2, p. 169-171 3 p.

Research output: Contribution to journalArticle

16 Scopus citations

Estimation of the normal boiling point of organic compounds

Sanghvi, R. & Yalkowsky, S. H., Apr 12 2006, In : Industrial and Engineering Chemistry Research. 45, 8, p. 2856-2861 6 p.

Research output: Contribution to journalArticle

17 Scopus citations

Reformulation of a new vancomycin analog: An example of the importance of buffer species and strength

Johnson, J. L. H. & Yalkowsky, S. H., Jan 13 2006, In : AAPS PharmSciTech. 7, 1, 5.

Research output: Contribution to journalArticle

23 Scopus citations

Solubility prediction in octanol: a technical note.

Sepassi, K. & Yalkowsky, S. H., 2006, In : AAPS PharmSciTech. 7, 1

Research output: Contribution to journalArticle

Solubility prediction in Octanol: A technical note

Sepassi, K. & Yalkowsky, S. H., Mar 24 2006, In : AAPS PharmSciTech. 7, 1, p. E1-E8 26.

Research output: Contribution to journalArticle

23 Scopus citations

Solubilization of monovalent weak electrolytes by micellization or complexation

He, Y. & Yalkowsky, S. H., May 11 2006, In : International Journal of Pharmaceutics. 314, 1, p. 15-20 6 p.

Research output: Contribution to journalArticle

15 Scopus citations

Solubilization of two structurally related anticancer drugs: XK-469 and PPA

He, Y., Tabibi, S. E. & Yalkowsky, S. H., Jan 2006, In : Journal of pharmaceutical sciences. 95, 1, p. 97-107 11 p.

Research output: Contribution to journalArticle

12 Scopus citations

The besylate salt of carbendazim: 2-(methoxy-carbonylamino)benzimidazolium benzenesulfonate

Sepassi, K., Sanghvi, T. & Yalkowsky, S. H., Oct 1 2006, In : Acta Crystallographica Section E: Structure Reports Online. 62, 10, p. o4403-o4404

Research output: Contribution to journalArticle

3 Scopus citations