• 788 Citations
  • 12 h-Index
19982018
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Polypyrimidine Tract-Binding Protein Medicine & Life Sciences
Exons Medicine & Life Sciences
RNA Precursors Medicine & Life Sciences
Spliceosomes Medicine & Life Sciences
RNA-Binding Proteins Medicine & Life Sciences
RNA Splice Sites Medicine & Life Sciences
Proteins Medicine & Life Sciences
Protein Splicing Medicine & Life Sciences

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Projects 2012 2015

Myelodysplastic Syndromes
Mutation
Protein Splicing
Hematopoiesis
RNA Splicing Factors

Research Output 1998 2018

  • 788 Citations
  • 12 h-Index
  • 20 Article
  • 2 Chapter

Myeloid Disease Mutations of Splicing Factor SRSF2 Cause G2-M Arrest and Skewed Differentiation of Human Hematopoietic Stem and Progenitor Cells

Bapat, A., Keita, N., Martelly, W., Kang, P., Seet, C., Jacobsen, J. R., Stoilov, P., Hu, C., Crooks, G. M. & Sharma, S., Jan 1 2018, (Accepted/In press) In : Stem Cells.

Research output: Contribution to journalArticle

Hematopoietic Stem Cells
Mutation
Stem Cells
RNA Splicing Factors
Leukemia, Myelomonocytic, Chronic
8 Citations (Scopus)

Large-scale remodeling of a repressed exon ribonucleoprotein to an exon definition complex active for splicing

Wongpalee, S. P., Vashisht, A., Sharma, S., Chui, D., Wohlschlegel, J. A. & Black, D. L., Nov 24 2016, In : eLife. 5, NOVEMBER2016, e19743.

Research output: Contribution to journalArticle

Ribonucleoproteins
Exons
U2 Small Nuclear Ribonucleoproteins
Polypyrimidine Tract-Binding Protein
U1 Small Nuclear Ribonucleoproteins
8 Citations (Scopus)

Multiple determinants of splicing repression activity in the polypyrimidine tract binding proteins, PTBP1 and PTBP2

Keppetipola, N. M., Yeom, K. H., Hernandez, A. L., Bui, T., Sharma, S. & Black, D. L., Aug 1 2016, In : RNA. 22, 8, p. 1172-1180 9 p.

Research output: Contribution to journalArticle

Polypyrimidine Tract-Binding Protein
Exons
Proteins
RNA-Binding Proteins
RNA Precursors
13 Citations (Scopus)

Stem–loop 4 of U1 snRNA is essential for splicing and interacts with the U2 snRNP-specific SF3A1 protein during spliceosome assembly

Sharma, S., Wongpalee, S. P., Vashisht, A., Wohlschlegel, J. A. & Black, D. L., Nov 15 2014, In : Genes and Development. 28, 22, p. 2518-2531 14 p.

Research output: Contribution to journalArticle

U2 Small Nuclear Ribonucleoproteins
Small Nuclear Ribonucleoproteins
Spliceosomes
RNA Splice Sites
Proteins
2 Citations (Scopus)

The pre-mRNA splicing reaction

Wongpalee, S. P. & Sharma, S., 2014, Methods in Molecular Biology. Humana Press Inc., Vol. 1126. p. 3-12 10 p. (Methods in Molecular Biology; vol. 1126).

Research output: Chapter in Book/Report/Conference proceedingChapter

RNA Precursors
Introns
Spliceosomes
Messenger RNA
Transcriptome