Projects per year
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- 2 Similar Profiles
Cations
Medicine & Life Sciences
Kidney
Medicine & Life Sciences
Microvilli
Medicine & Life Sciences
Rabbits
Medicine & Life Sciences
Proximal Kidney Tubule
Medicine & Life Sciences
Tetraethylammonium
Medicine & Life Sciences
Membranes
Medicine & Life Sciences
Mytilus
Medicine & Life Sciences
Network
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Projects 1983 2017
Improving In Vitro-In Vivo Extrapolation for Renal Cationic Drug Transport
Project: Research project
Molecular Organization of the Organic cation-Proton Exchanger, MATE1
Wright, S. & Chang, G.
7/17/09 → 7/31/16
Project: Research project › High Priority, Short Term Project Award, Research Project
Cations
Protons
Kidney
Drug Interactions
Liver
Molecular Organization of Renal Organic Anion Transport
2/1/06 → 1/31/12
Project: Research project › Research Project
anions
kidneys
transporters
Anions
Kidney
Regulation of Renal Xenobiotic Transport by Estrogens
Wright, S. & Groves, C.
9/1/03 → 8/31/08
Project: Research project › Research Project
xenobiotics
anions
estrogens
kidneys
proximal tubules
RENAL TRANSPORT OF ORGANIC CHELATORS OF HEAVY METALS
2/1/01 → 1/31/07
Project: Research project › Research Project
Chelating Agents
Heavy Metals
Kidney
Anions
Organic Anion Transporters
Research Output 1975 2018
Assessment of substrate-dependent ligand interactions at the organic cation transporter OCT2 using six model substrates s
Sandoval, P. J., Zorn, K. M., Clark, A. M., Ekins, S. & Wright, S. H., Sep 1 2018, In : Molecular Pharmacology. 94, 3, p. 1057-1068 12 p.Research output: Contribution to journal › Article
Metformin
Cations
Ligands
Drug Interactions
Decision Trees
4
Citations
Correlation between apparent substrate affinity and OCT2 transport turnover
Severance, A. C., Sandoval, P. J. & Wright, S. H., Sep 1 2017, In : Journal of Pharmacology and Experimental Therapeutics. 362, 3, p. 405-412 8 p.Research output: Contribution to journal › Article
1-Methyl-4-phenylpyridinium
Cations
Pharmacokinetics
Pharmaceutical Preparations
Kidney
4
Citations
Lack of influence of substrate on ligand interaction with the human multidrug and toxin extruder, MATE1
Martínez-Guerrero, L. J., Morales, M., Ekins, S. & Wright, S. H., Sep 1 2016, In : Molecular Pharmacology. 90, 3, p. 254-264 11 p.Research output: Contribution to journal › Article
Cations
Ligands
Inhibitory Concentration 50
Pharmaceutical Preparations
1-Methyl-4-phenylpyridinium
2
Citations
The multidrug transporter MATE1 sequesters OCs within an intracellular compartment that has no influence on OC secretion in renal proximal tubules
Martínez-Guerrero, L. J., Evans, K. K., Dantzler, W. H. & Wright, S. H., 2015, In : American Journal of Physiology - Renal Physiology. 310, 1, p. F57-F67Research output: Contribution to journal › Article
Proximal Kidney Tubule
Cations
1-Methyl-4-phenylpyridinium
Cricetulus
Adenosine Triphosphatases
7
Citations
Unstirred Water Layers and the Kinetics of Organic Cation Transport
Shibayama, T., Morales, M., Zhang, X., Martínez-Guerrero, L. J., Berteloot, A., Secomb, T. W. & Wright, S. H., Sep 8 2015, In : Pharmaceutical Research. 32, 9, p. 2937-2949 13 p., 1675Research output: Contribution to journal › Article
Cations
Kinetics
Water
CHO Cells
Cultured Cells