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Steven D Schwartz

  • 3509 Citations
  • 29 h-Index
1982 …2020

Research output per year

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Projects

Rapid protein dynamics and catalysis: modulation by laboratory evolution, designed mutation, and protein control of electric field environment

Schwartz, S. D.

Project: Research project

A New Paradigm to Incorporate Protein Dynamics into Targeted Small Molecule Design for Sarcomeric Cardiomyopathies: A Proof of Concept for Thin Filament Therapeutics

Schwartz, S. D. & Tardiff, J. C.

Project: Research project

Quantum Nuclear Dynamics and Enzyme Chemistry

Schwartz, S. D.

National Institutes of Health

9/1/12 → 6/30/15

Project: Research project

    • A molecular study linking cTnT dynamics to genetic cardiomyopathy

    Tardiff, J. C. & Schwartz, S. D.

    National Institutes of Health

    12/15/10 → 2/29/20

    Project: Research project

    • Protein Dynamics in Enzymatic Catalysis

    Schwartz, S. D., Dyer, R. B., Schramm, V. L. & Callender, R.

    National Institutes of Health

    5/1/04 → 4/30/19

    Project: Research project

    • Research Output

    A Classical Molecular Dynamics Simulation Study of Interfacial and Bulk Solution Aggregation Properties of Dirhamnolipids

    Luft, C. M., Munusamy, E., Pemberton, J. E. & Schwartz, S. D., Feb 6 2020, In : Journal of Physical Chemistry B. 124, 5, p. 814-827 14 p.

    Research output: Contribution to journal › Article

    • Examining the origin of catalytic power of Catechol O-Methyltransferase

    Chen, X. & Schwartz, S. D., Jan 1 2019, (Accepted/In press) In : ACS Catalysis.

    Research output: Contribution to journal › Article

    • FRET-based analysis of the cardiac troponin T linker region reveals the structural basis of the hypertrophic cardiomyopathy-causing Δ160E mutation

    Abdullah, S., Lynn, M. L., McConnell, M. T., Klass, M. M., Baldo, A. P., Schwartz, S. D. & Tardiff, J. C., Oct 4 2019, In : Journal of Biological Chemistry. 294, 40, p. 14634-14647 14 p.

    Research output: Contribution to journal › Article

    • 2 Scopus citations

    Optimization of the Turnover in Artificial Enzymes via Directed Evolution Results in the Coupling of Protein Dynamics to Chemistry

    Schafer, J. W., Zoi, I., Antoniou, D. & Schwartz, S. D., Jul 3 2019, In : Journal of the American Chemical Society. 141, 26, p. 10431-10439 9 p.

    Research output: Contribution to journal › Article

    • 4 Scopus citations

    Proof of Principle that Molecular Modeling Followed by a Biophysical Experiment Can Develop Small Molecules that Restore Function to the Cardiac Thin Filament in the Presence of Cardiomyopathic Mutations

    Szatkowski, L., Lynn, M. L., Holeman, T., Williams, M. R., Baldo, A. P., Tardiff, J. C. & Schwartz, S. D., Apr 9 2019, In : ACS Omega. 4, 4, p. 6492-6501 10 p.

    Research output: Contribution to journal › Article

    Open Access
    • 2 Scopus citations