Projects per year
Fingerprint Dive into the research topics where Steven D Schwartz is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
Enzymes
Chemical Compounds
enzymes
Physics & Astronomy
dehydrogenases
Physics & Astronomy
Catalysis
Chemical Compounds
L-Lactate Dehydrogenase
Chemical Compounds
Proteins
Engineering & Materials Science
Hamiltonians
Chemical Compounds
Sampling
Chemical Compounds
Network
Recent external collaboration on country level. Dive into details by clicking on the dots.
Projects 2004 2020
A molecular study linking cTnT dynamics to genetic cardiomyopathy
Tardiff, J. C. & Schwartz, S. D.
12/15/10 → 2/29/20
Project: Research project
Cardiomyopathies
Mutation
Familial Hypertrophic Cardiomyopathy
Phosphorylation
Biological Control Agents
Enzymes
Alcohol Dehydrogenase
Sampling
Quantum theory
Biological systems
Protein Dynamics in Enzymatic Catalysis
Schwartz, S. D., Dyer, R. B., Schramm, V. L. & Callender, R.
5/1/04 → 4/30/19
Project: Research project
Enzymes
Proteins
vibration
lactates
dehydrogenases
Research Output 1982 2019
Examining the origin of catalytic power of Catechol O-Methyltransferase
Chen, X. & Schwartz, S. D., Jan 1 2019, (Accepted/In press) In : ACS Catalysis.Research output: Contribution to journal › Article
Catechol O-Methyltransferase
Enzymes
Computational chemistry
Electrostatics
Electric fields
FRET-based analysis of the cardiac troponin T linker region reveals the structural basis of the hypertrophic cardiomyopathy-causing Δ160E mutation
Abdullah, S., Lynn, M. L., McConnell, M. T., Klass, M. M., Baldo, A. P., Schwartz, S. D. & Tardiff, J. C., Jan 1 2019, In : Journal of Biological Chemistry. 294, 40, p. 14634-14647 14 p.Research output: Contribution to journal › Article
Troponin T
Hypertrophic Cardiomyopathy
Actomyosin
Tropomyosin
Mutation
1
Citation
(Scopus)
Optimization of the Turnover in Artificial Enzymes via Directed Evolution Results in the Coupling of Protein Dynamics to Chemistry
Schafer, J. W., Zoi, I., Antoniou, D. & Schwartz, S. D., Jan 1 2019, In : Journal of the American Chemical Society.Research output: Contribution to journal › Article
Enzymes
Proteins
Fructose-Bisphosphate Aldolase
Aldehyde-Lyases
Trajectories
1
Citation
(Scopus)
Proof of Principle that Molecular Modeling Followed by a Biophysical Experiment Can Develop Small Molecules that Restore Function to the Cardiac Thin Filament in the Presence of Cardiomyopathic Mutations
Szatkowski, L., Lynn, M. L., Holeman, T., Williams, M. R., Baldo, A. P., Tardiff, J. C. & Schwartz, S. D., Apr 9 2019, In : ACS Omega. 4, 4, p. 6492-6501 10 p.Research output: Contribution to journal › Article
Open Access
Molecular modeling
Molecules
Experiments
Docks
Animals
3
Citations
(Scopus)
Directed Evolution as a Probe of Rate Promoting Vibrations Introduced via Mutational Change
Chen, X. & Schwartz, S. D., Jun 12 2018, In : Biochemistry. 57, 23, p. 3289-3298 10 p.Research output: Contribution to journal › Article
Vibration
Catalytic Domain
Enzymes
Sampling
Proteins