• 3379 Citations
  • 29 h-Index
1982 …2020
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Fingerprint Dive into the research topics where Steven D Schwartz is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

Enzymes Chemical Compounds
enzymes Physics & Astronomy
dehydrogenases Physics & Astronomy
Catalysis Chemical Compounds
L-Lactate Dehydrogenase Chemical Compounds
Proteins Engineering & Materials Science
Hamiltonians Chemical Compounds
Sampling Chemical Compounds

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Projects 2004 2020

Cardiomyopathies
Mutation
Familial Hypertrophic Cardiomyopathy
Phosphorylation
Biological Control Agents
Enzymes
Alcohol Dehydrogenase
Sampling
Quantum theory
Biological systems

Protein Dynamics in Enzymatic Catalysis

Schwartz, S. D., Dyer, R. B., Schramm, V. L. & Callender, R.

National Institutes of Health

5/1/044/30/19

Project: Research project

Enzymes
Proteins
vibration
lactates
dehydrogenases

Research Output 1982 2019

  • 3379 Citations
  • 29 h-Index
  • 114 Article
  • 3 Chapter
  • 2 Review article
1 Citation (Scopus)
Enzymes
Proteins
Fructose-Bisphosphate Aldolase
Aldehyde-Lyases
Trajectories
1 Citation (Scopus)

Proof of Principle that Molecular Modeling Followed by a Biophysical Experiment Can Develop Small Molecules that Restore Function to the Cardiac Thin Filament in the Presence of Cardiomyopathic Mutations

Szatkowski, L., Lynn, M. L., Holeman, T., Williams, M. R., Baldo, A. P., Tardiff, J. C. & Schwartz, S. D., Apr 9 2019, In : ACS Omega. 4, 4, p. 6492-6501 10 p.

Research output: Contribution to journalArticle

Open Access
Molecular modeling
Molecules
Experiments
Docks
Animals
3 Citations (Scopus)

Directed Evolution as a Probe of Rate Promoting Vibrations Introduced via Mutational Change

Chen, X. & Schwartz, S. D., Jun 12 2018, In : Biochemistry. 57, 23, p. 3289-3298 10 p.

Research output: Contribution to journalArticle

Vibration
Catalytic Domain
Enzymes
Sampling
Proteins
5 Citations (Scopus)

Inverse enzyme isotope effects in human purine nucleoside phosphorylase with heavy asparagine labels

Harijan, R. K., Zoi, I., Antoniou, D., Schwartz, S. D. & Schramm, V. L., Jul 3 2018, In : Proceedings of the National Academy of Sciences of the United States of America. 115, 27, p. E6209-E6216

Research output: Contribution to journalArticle

Purine-Nucleoside Phosphorylase
Asparagine
Isotopes
Catalytic Domain
Enzymes
3 Citations (Scopus)

Mechanistic Insights on Human Phosphoglucomutase Revealed by Transition Path Sampling and Molecular Dynamics Calculations

Brás, N. F., Fernandes, P. A., Ramos, M. J. & Schwartz, S. D., Feb 6 2018, In : Chemistry - A European Journal. 24, 8, p. 1978-1987 10 p.

Research output: Contribution to journalArticle

Phosphoglucomutase
Glucose
Molecular dynamics
Glucose-6-Phosphate
Sampling