Thomas C Doetschman

  • 18859 Citations
  • 64 h-Index
1975 …2021
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Fibroblast Growth Factor 2 Medicine & Life Sciences
Transforming Growth Factors Medicine & Life Sciences
Protein Isoforms Medicine & Life Sciences
Embryonic Stem Cells Medicine & Life Sciences
Genes Medicine & Life Sciences
Transforming Growth Factor beta Medicine & Life Sciences
Gene Targeting Medicine & Life Sciences
Embryoid Bodies Medicine & Life Sciences

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Projects 1978 2021


Davis, T. P., Hersh, E. M., Weinstein, R. S., Miesfeld, R., Miller, T. P., Tsaprailis, G., Lynch, R., Chow, H., Nagle, R. B., Watts, G. S., Thomson, C., Roe, D., Stratton, S. P., Alberts, D. S., Hurley, L., Baker, A. F., Livingston, R. B., Dorr, R. T., Cress, A. E., Briehl, M. M., Mash, E. A., Duffy, J., Jones, S., Leibovitz, A., Meyskens, F., Moon, T., Trent, J., Newkirk, D., Von Hoff, D., Mount, D., Doetschman, T., Liebler, D., Marshall, J., McGovern, K., Grogan, T., Kraft, A., Powis, G., Peng, Y., Gerner, E., Aickin, M., Ritenbaugh, C., Taylor, C., Powell, M. B., Bowden, T., Taetle, R., Salmon, S., Ignatenko, N., Bhattacharyya, A. K., Futscher, B. W., Barton, J. K., Montfort, W. "., Roe, D., Garland, L. L., Doetschman, T. C., Kraft, A., Chow, H. & Ellis, N.

National Institutes of Health


Project: Research projectCenter Core Grants

Pharmaceutical Services
Research Personnel
Clinical Trials
Green Fluorescent Proteins
Cell Nucleus

Regulation of Periostin by TGFbeta and BMP in Heart Development

Doetschman, T. C. & Conway, S. J.

National Institutes of Health


Project: Research projectResearch Project

Transforming Growth Factor beta
Ehlers-Danlos Syndrome
Mitral Valve Prolapse
Marfan Syndrome
Heart Valves
Transforming Growth Factor beta
Autoimmune Diseases

Roles of FGF2 and TGFbeta in cardiac hypertrophy

Doetschman, T. C.

National Institutes of Health


Project: Research projectResearch Project

Fibroblast Growth Factor 2
Transforming Growth Factor beta
Intercellular Signaling Peptides and Proteins

Research Output 1975 2018

  • 18859 Citations
  • 64 h-Index
  • 161 Article
  • 5 Chapter
  • 1 Comment/debate
  • 1 Review article

Ablation of low-molecular-weight FGF2 isoform accelerates murine osteoarthritis while loss of high-molecular-weight FGF2 isoforms offers protection

Burt, P. M., Xiao, L., Doetschman, T. & Hurley, M. M., Jan 1 2018, (Accepted/In press) In : Journal of Cellular Physiology.

Research output: Contribution to journalArticle

Fibroblast Growth Factor 2
Protein Isoforms
Molecular Weight
2 Citations

Functional changes in the gut microbiome contribute to transforming growth factor β-deficient colon cancer

Daniel, S. G., Ball, C. L., Besselsen, D. G., Doetschman, T. & Hurwitze, B. L., Sep 1 2017, In : mSystems. 2, 5, e00065

Research output: Contribution to journalArticle

Helicobacter hepaticus
functional change
Growth Factors
transforming growth factor beta
13 Citations

Gene Editing with CRISPR/Cas9 RNA-Directed Nuclease

Doetschman, T. & Georgieva, T., Mar 3 2017, In : Circulation Research. 120, 5, p. 876-894 19 p.

Research output: Contribution to journalReview article

Long Noncoding RNA
Therapeutic Human Experimentation
Genetic Engineering

2-Photon Characterization of Optical Proteolytic Beacons for Imaging Changes in Matrix-Metalloprotease Activity in a Mouse Model of Aneurysm

Haskett, D. G., Maestas, D., Howerton, S. J., Smith, T., Ardila, D. C., Doetschman, T., Utzinger, U., McGrath, D., McIntyre, J. O. & Vande Geest, J. P., Feb 23 2016, (Accepted/In press) In : Microscopy and Microanalysis. p. 1-12 12 p.

Research output: Contribution to journalArticle

Imaging techniques
7 Citations

Biomechanical Comparison of Glutaraldehyde-Crosslinked Gelatin Fibrinogen Electrospun Scaffolds to Porcine Coronary Arteries

Tamimi, E., Ardila, D. C., Haskett, D. G., Doetschman, T., Slepian, M. J., Kellar, R. S. & Vande Geest, J. P., Jan 1 2016, In : Journal of Biomechanical Engineering. 138, 1, 011001

Research output: Contribution to journalArticle