• 1715 Citations
  • 18 h-Index
19962018

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2017

A dominant-negative mutant inhibits multiple prion variants through a common mechanism

Pei, F., DiSalvo, S., Sindi, S. S. & Serio, T. R., Oct 2017, In : PLoS genetics. 13, 10, e1007085.

Research output: Contribution to journalArticle

6 Scopus citations

Estimating the rate of prion aggregate amplification in yeast with a generation and structured population model

Banks, H. T., Flores, K. B., Langlois, C. R., Serio, T. R. & Sindi, S. S., Apr 18 2017, (Accepted/In press) In : Inverse Problems in Science and Engineering. p. 1-23 23 p.

Research output: Contribution to journalArticle

1 Scopus citations

Susan Lindquist (1949-2016)

Serio, T. R., Jan 19 2017, In : Nature Chemical Biology. 13, 2, 1 p.

Research output: Contribution to journalArticle

1 Scopus citations

What’s in a name?

Schaller, M. D., McDowell, G., Porter, A., Shippen, D., Friedman, K. L., Gentry, M. S., Serio, T. R. & Sundquist, W. I., Oct 24 2017, In : eLife. 6, e32437.

Research output: Contribution to journalArticle

5 Scopus citations
2016

Distinct Prion Domain Sequences Ensure Efficient Amyloid Propagation by Promoting Chaperone Binding or Processing In Vivo

Langlois, C. R., Pei, F., Sindi, S. S. & Serio, T. R., Nov 2016, In : PLoS genetics. 12, 11, e1006417.

Research output: Contribution to journalArticle

6 Scopus citations
2014

Amyloid-associated activity contributes to the severity and toxicity of a prion phenotype

Pezza, J. A., Villali, J., Sindi, S. S. & Serio, T. R., Jul 15 2014, In : Nature communications. 5, 4384.

Research output: Contribution to journalArticle

24 Scopus citations

Loss of amino-terminal acetylation suppresses a prion phenotype by modulating global protein folding

Holmes, W. M., Mannakee, B. K., Gutenkunst, R. N. & Serio, T. R., Jul 15 2014, In : Nature communications. 5, 4383.

Research output: Contribution to journalArticle

53 Scopus citations

Organelle and proteome quality control mechanisms: How cells are able to keep calm and carry on

Brodsky, J. L., Merz, A. & Serio, T., Mar 15 2014, In : Molecular biology of the cell. 25, 6, p. 733-734 2 p.

Research output: Contribution to journalArticle

1 Scopus citations

Spatial quality control bypasses cell-based limitations on proteostasis to promote prion curing

Klaips, C. L., Hochstrasser, M. L., Langlois, C. R. & Serio, T. R., 2014, In : eLife. 3

Research output: Contribution to journalArticle

30 Scopus citations
2011

Dominant prion mutants induce curing through pathways that promote chaperone-mediated disaggregation

Disalvo, S., Derdowski, A., Pezza, J. A. & Serio, T. R., Apr 1 2011, In : Nature Structural and Molecular Biology. 18, 4, p. 486-493 8 p.

Research output: Contribution to journalArticle

34 Scopus citations
2010

A size threshold limits prion transmission and establishes phenotypic diversity

Derdowski, A., Sindi, S. S., Klaips, C. L., DiSalvo, S. & Serio, T. R., Oct 29 2010, In : Science. 330, 6004, p. 680-683 4 p.

Research output: Contribution to journalArticle

75 Scopus citations
2009

The NatA acetyltransferase couples sup35 prion complexes to the [PSI +] Phenotype

Pezza, J. A., Langseth, S. X., Yamamoto, R. R., Doris, S. M., Ulin, S. P., Salomon, A. R. & Serio, T. R., Jan 1 2009, In : Molecular biology of the cell. 20, 3, p. 1068-1080 13 p.

Research output: Contribution to journalArticle

14 Scopus citations
2007

Hsp104-dependent remodeling of prion complexes mediates protein-only inheritance

Satpute-Krishnan, P., Langseth, S. X. & Serio, T. R., Feb 1 2007, In : PLoS biology. 5, 2, p. 251-262 12 p.

Research output: Contribution to journalArticle

102 Scopus citations
2005

Prion protein remodelling confers an immediate phenotypic switch

Satpute-Krishnan, P. & Serio, T. R., Sep 8 2005, In : Nature. 437, 7056, p. 262-265 4 p.

Research output: Contribution to journalArticle

70 Scopus citations
2001

Self-perpetuating changes in Sup35 protein conformation as a mechanism of heredity in yeast

Serio, T. R., Cashikar, A. G., Kowal, A. S., Sawicki, G. J. & Lindquist, S. L., Jan 1 2001, In : Biochemical Society Symposium. 68, p. 35-43 9 p.

Research output: Contribution to journalArticle

5 Scopus citations
2000

Nucleated conformational conversion and the replication of conformational information by a prion determinant

Serio, T. R., Cashikar, A. G., Kowal, A. S., Sawicki, G. J., Moslehi, J. J., Serpell, L., Arnsdorf, M. F. & Lindquist, S. L., Aug 25 2000, In : Science. 289, 5483, p. 1317-1321 5 p.

Research output: Contribution to journalArticle

757 Scopus citations
1999

Yeast prion [Ψ+] and its determinant, Sup35p

Serio, T. R., Cashikar, A. G., Moslehi, J. J., Kowal, A. S. & Lindquist, S. L., Jan 1 1999, In : Methods in Enzymology. 309, p. 649-673 25 p.

Research output: Contribution to journalArticle

67 Scopus citations
1998

A functionally distinct TATA box required for late progression through the Epstein-Barr virus life cycle

Serio, T. R., Cahill, N., Prout, M. E. & Miller, G., Sep 23 1998, In : Journal of virology. 72, 10, p. 8338-8343 6 p.

Research output: Contribution to journalArticle

35 Scopus citations

Amyloid fibres of Sup35 support a prion-like mechanism of inheritance in yeast

Lindquist, S., Debburman, S. K., Glover, J. R., Kowal, A. S., Liu, J. J., Schirmer, E. C. & Serio, T. R., Jan 1 1998, In : Biochemical Society transactions. 26, 3, p. 486-490 5 p.

Research output: Contribution to journalArticle

8 Scopus citations
1997

Late gene expression from the Epstein-Barr virus BclF1 and BFRF3 promoters does not require DNA replication in cis

Serio, T. R., Kolman, J. L. & Miller, G., Nov 1 1997, In : Journal of virology. 71, 11, p. 8726-8734 9 p.

Research output: Contribution to journalArticle

36 Scopus citations
1996

Two 21-kilodalton components of the Epstein-Barr virus capsid antigen complex and their relationship to ZEBRA-associated protein p21 (ZAP21)

Serio, T. R., Angelont, A., Kolman, J. L., Gradoville, L., Sun, R., Katz, D. A., Van Grunsven, W., Middeldorp, J. & Miller, G., Nov 1 1996, In : Journal of virology. 70, 11, p. 8047-8054 8 p.

Research output: Contribution to journalArticle

28 Scopus citations