• 3621 Citations
  • 30 h-Index
1990 …2019

Research output per year

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Research Output

Article

2-Photon Characterization of Optical Proteolytic Beacons for Imaging Changes in Matrix-Metalloprotease Activity in a Mouse Model of Aneurysm

Haskett, D. G., Maestas, D., Howerton, S. J., Smith, T., Ardila, D. C., Doetschman, T. C., Utzinger, U., Mcgrath, D. V., McIntyre, J. O. & Vande Geest, J. P., Feb 23 2016, (Accepted/In press) In : Microscopy and Microanalysis. p. 1-12 12 p.

Research output: Contribution to journalArticle

4-HPR modulates gene expression in ovarian cells

Brewer, M., Kirkpatrick, N. D., Wharton, J. T., Wang, J., Hatch, K., Auersperg, N., Utzinger, U., Gershenson, D., Bast, R. & Zou, C., Sep 1 2006, In : International Journal of Cancer. 119, 5, p. 1005-1013 9 p.

Research output: Contribution to journalArticle

7 Scopus citations
34 Scopus citations

A gimbal-mounted pressurization chamber for macroscopic and microscopic assessment of ocular tissues

Keyes, J. T., Yan, D., Rader, J. H., Utzinger, U. & Vande Geest, J. P., Oct 28 2011, In : Journal of Biomechanical Engineering. 133, 9, 095001.

Research output: Contribution to journalArticle

6 Scopus citations

A multiresolution approach for enhancement and denoising of microscopy images

Bal, U., Engin, M. & Utzinger, U., Jan 1 2015, In : Signal, Image and Video Processing. 9, 4, p. 787-799 13 p.

Research output: Contribution to journalArticle

3 Scopus citations

Analysis of second-harmonic-generation microscopy in a mouse model of ovarian carcinoma

Watson, J. M., Rice, P. F., Marion, S. L., Brewer, M. A., Davis, J. R., Rodriguez, J. J., Utzinger, U., Hoyer, P. B. & Bartona, J. K., Jul 1 2012, In : Journal of biomedical optics. 17, 7, 076002.

Research output: Contribution to journalArticle

20 Scopus citations

Biomarker modulation in a nonhuman rhesus primate model for ovarian cancer chemoprevention

Brewer, M., Utzinger, U., Satterfield, W., Hill, L., Gershenson, D., Bast, R., Wharton, J. T., Richards-Kortum, R. & Follen, M., Jan 1 2001, In : Cancer Epidemiology Biomarkers and Prevention. 10, 8, p. 889-893 5 p.

Research output: Contribution to journalArticle

11 Scopus citations

Cancer screening through the use of enhanced visual systems

Utzinger, U., Bueeler, M., Heintzelman, D. L., Gillenwater, A. & Richards-Kortum, R., Jan 1 2001, In : Proceedings of SPIE- The International Society for Optical Engineering. 4259, p. 22-23 2 p.

Research output: Contribution to journalArticle

Cervical fluorescence of normal women

Brookner, C. K., Utzinger, U., Staerkel, G., Richards-Kortum, R. & Mitchell, M. F., Feb 15 1999, In : Lasers in Surgery and Medicine. 24, 1, p. 29-37 9 p.

Research output: Contribution to journalArticle

37 Scopus citations

Clinical research device for ovarian cancer detection by optical spectroscopy in the ultraviolet C-visible

George, R., Chandrasekaran, A., Brewer, M. A., Hatch, K. D. & Utzinger, U., Sep 1 2010, In : Journal of biomedical optics. 15, 5, 057009.

Research output: Contribution to journalArticle

8 Scopus citations

Comparisons of planar and tubular biaxial tensile testing protocols of the same porcine coronary arteries

Keyes, J. T., Lockwood, D. R., Utzinger, U., Montilla, L. G., Witte, R. S. & Vande Geest, J. P., Jul 1 2013, In : Annals of Biomedical Engineering. 41, 7, p. 1579-1591 13 p.

Research output: Contribution to journalArticle

18 Scopus citations

Coronary vasomotion during dynamic exercise: Influence of intravenous and intracoronary nicardipine

Kaufmann, P., Vassalli, G., Utzinger, URS. & Hess, O. M., Sep 1995, In : Journal of the American College of Cardiology. 26, 3, p. 624-631 8 p.

Research output: Contribution to journalArticle

26 Scopus citations

Depth-sensitive reflectance measurements using obliquely oriented fiber probes

Wang, A. M. J., Bender, J. E., Pfefer, J., Utzinger, U. & Drezek, R. A., Jul 1 2005, In : Journal of biomedical optics. 10, 4, 044017.

Research output: Contribution to journalArticle

39 Scopus citations

Design and characterization of a combined OCT and wide field imaging falloposcope for ovarian cancer detection

Keenan, M., Tate, T. H., Kieu, K., Black, J. F., Utzinger, U. & Barton, J. K., Jan 1 2017, In : Biomedical Optics Express. 8, 1, p. 124-136 13 p., #279464.

Research output: Contribution to journalArticle

9 Scopus citations

Design and demonstration of a microbiaxial optomechanical device for multiscale characterization of soft biological tissues with two-photon microscopy

Keyes, J. T., Borowicz, S. M., Rader, J. H., Utzinger, U., Azhar, M. & Vande Geest, J. P., Apr 1 2011, In : Microscopy and Microanalysis. 17, 2, p. 167-175 9 p.

Research output: Contribution to journalArticle

23 Scopus citations

Detecting the signal of the menstrual cycle in fluorescence spectroscopy of the cervix

Cox, D. D., Chang, S. K., Dawood, M. Y., Staerkel, G., Utzinger, U., Richards-Kortum, R. R. & Follen, M., Jan 1 2003, In : Applied Spectroscopy. 57, 1, p. 67-72 6 p.

Research output: Contribution to journalArticle

13 Scopus citations

Development of a Fiber Optic Probe to Measure NIR Raman Spectra of Cervical Tissue in Vivo

Mahadevan-Jansen, A., Mitchell, M. F., Ramanujam, N., Utzinger, U. & Richards-Kortum, R., Sep 1998, In : Photochemistry and Photobiology. 68, 3, p. 427-431 5 p.

Research output: Contribution to journalArticle

171 Scopus citations

Differences in the microstructure and biomechanical properties of the recurrent laryngeal nerve as a function of age and location

Williams, M. J., Utzinger, U., Barkmeier-Kraemer, J. M. & Geest, J. P. V., Aug 2014, In : Journal of Biomechanical Engineering. 136, 8, 081008.

Research output: Contribution to journalArticle

9 Scopus citations

Effects of biographical variables on cervical fluorescence emission spectra

Brookner, C., Utzinger, U., Follen, M., Richards-Kortum, R., Cox, D. & Atkinson, E. N., Jul 1 2003, In : Journal of biomedical optics. 8, 3, p. 479-483 5 p.

Research output: Contribution to journalArticle

30 Scopus citations

Endogenous fluorescence spectroscopy of cell suspensions for chemopreventive drug monitoring

Kirkpatrick, N. D., Zou, C., Brewer, M. A., Brands, W. R., Drezek, R. A. & Utzinger, U., Jan 1 2005, In : Photochemistry and Photobiology. 81, 1, p. 125-134 10 p.

Research output: Contribution to journalArticle

79 Scopus citations

Endogenous optical biomarkers of ovarian cancer evaluated with multiphoton microscopy

Kirkpatrick, N. D., Brewer, M. A. & Utzinger, U., Oct 1 2007, In : Cancer Epidemiology Biomarkers and Prevention. 16, 10, p. 2048-2057 10 p.

Research output: Contribution to journalArticle

103 Scopus citations

Endoscopic optical coherence tomography and laser-induced fluorescence spectroscopy in a murine colon cancer model

Hariri, L. P., Tumlinson, A. R., Besselsen, D. G., Utzinger, U., Gerner, E. W. & Barton, J. K., Apr 1 2006, In : Lasers in Surgery and Medicine. 38, 4, p. 305-313 9 p.

Research output: Contribution to journalArticle

66 Scopus citations

Enhanced visibility of colonic neoplasms using formulaic ratio imaging of native fluorescence

Banerjee, B., Rial, N. S., Renkoski, T., Graves, L. R., Reid, S. A. H., Hu, C., Tsikitis, V. L., Nfonsom, V., Pugh, J. & Utzinger, U., Nov 1 2013, In : Lasers in Surgery and Medicine. 45, 9, p. 573-581 9 p.

Research output: Contribution to journalArticle

4 Scopus citations

Excimer laser spectroscopy: Influence of tissue ablation on vessel wall fluorescence

Strebel, R. T., Utzinger, U., Peltola, M., Schneider, J., Niederer, P. F. & Hess, O. M., Feb 1998, In : Journal of Laser Applications. 10, 1, p. 34-40 7 p.

Research output: Contribution to journalArticle

5 Scopus citations

Ex vivo optical coherence tomography and laser-induced fluorescence spectroscopy imaging of murine gastrointestinal tract

Hariri, L. P., Tumlinson, A. R., Wade, N. H., Besselsen, D. G., Utzinger, U., Gerner, E. W. & Barton, J. K., Apr 1 2007, In : Comparative medicine. 57, 2, p. 175-185 11 p.

Research output: Contribution to journalArticle

27 Scopus citations

Fiber optic probe for polarized reflectance spectroscopy in vivo: Design and performance

Myakov, A., Nieman, L., Wicky, L., Utzinger, U., Richards-Kortum, R. & Sokolov, K., Jul 1 2002, In : Journal of biomedical optics. 7, 3, p. 388-397 10 p.

Research output: Contribution to journalArticle

65 Scopus citations

Fiber optic probes for biomedical optical spectroscopy

Utzinger, U. & Richards-Kortum, R. R., Jan 1 2003, In : Journal of biomedical optics. 8, 1, p. 121-147 27 p.

Research output: Contribution to journalArticle

381 Scopus citations

Fluorescence excitation emission matrices of human tissue: a system for in vivo measurement and method of data analysis

Zuluaga, A. F., Utzinger, U., Durkin, A., Fuchs, H., Gillenwater, A., Jacob, R., Kemp, B., Fan, J. & Richards-Kortum, R., Mar 1999, In : Applied Spectroscopy. 53, 3, p. 302-311 10 p.

Research output: Contribution to journalArticle

95 Scopus citations

Fluorescence spectroscopy as a biomarker in a cell culture and in a nonhuman primate model for ovarian cancer chemopreventive agents

Brewer, M., Utzinger, U., Li, Y., Atkinson, E. N., Satterfield, W., Auersperg, N., Richards-Kortum, R., Follen, M. & Bast, R., Jan 2002, In : Journal of biomedical optics. 7, 1, p. 20-26 7 p.

Research output: Contribution to journalArticle

29 Scopus citations

Fluorescence spectroscopy for cervical precancer detection: Is there variance across the menstrual cycle?

Chang, S. K., Dawood, M. Y., Staerkel, G., Utzinger, U., Atkinson, E. N., Richards-Kortum, R. R. & Follen, M., Oct 1 2002, In : Journal of biomedical optics. 7, 4, p. 595-602 8 p.

Research output: Contribution to journalArticle

29 Scopus citations

Fluorescence spectroscopy for identification of atherosclerotic tissue

Bosshart, F., Utzinger, U., Hess, O. M., Wyser, J., Mueller, A., Schneider, J., Niederer, P., Anliker, M. & Krayenbuehl, H. P., Jun 1992, In : Cardiovascular research. 26, 6, p. 620-625 6 p.

Research output: Contribution to journalArticle

18 Scopus citations

Fluorescence spectroscopy for in vivo characterization of ovarian tissue

Brewer, M., Utzinger, U., Silva, E., Gershenson, D., Bast, R. C., Follen, M. & Richards-Kortum, R., Sep 12 2001, In : Lasers in Surgery and Medicine. 29, 2, p. 128-135 8 p.

Research output: Contribution to journalArticle

48 Scopus citations

Fluorescence spectroscopy of epithelial tissue throughout the dysplasia-carcinoma sequence in an animal model: Spectroscopic changes precede morphologic changes

Coghlan, L., Utzinger, U., Richards-Kortum, R., Brookner, C., Zuluaga, A., Gimenez-Conti, I. & Follen, M., Aug 18 2001, In : Lasers in Surgery and Medicine. 29, 1, p. 1-10 10 p.

Research output: Contribution to journalArticle

25 Scopus citations

Fluorescence spectroscopy of the cervix: Influence of acetic acid, cervical mucus, and vaginal medications

Agrawal, A., Utzinger, U., Brookner, C., Pitris, C., Mitchell, M. F. & Richards-Kortum, R., Oct 14 1999, In : Lasers in Surgery and Medicine. 25, 3, p. 237-249 13 p.

Research output: Contribution to journalArticle

46 Scopus citations

Gold nanorods targeted to delta opioid receptor: Plasmon-resonant contrast and photothermal agents

Black, K. C., Kirkpatrick, N. D., Troutman, T. S., Xu, L., Vagner, J., Gillies, R. J., Barton, J. K., Utzinger, U. & Romanowski, M., Jan 1 2008, In : Molecular imaging. 7, 1, p. 50-57 8 p.

Research output: Contribution to journalArticle

47 Scopus citations

High resolution, high speed, long working distance, large field of view confocal fluorescence microscope

Pacheco, S., Wang, C., Chawla, M. K., Nguyen, M., Baggett, B. K., Utzinger, U., Barnes, C. A. & Liang, R., Dec 1 2017, In : Scientific reports. 7, 1, 13349.

Research output: Contribution to journalArticle

7 Scopus citations

Imaging of the ovary

Brewer, M. A., Utzinger, U., Barton, J. K., Hoying, J. B., Kirkpatrick, N. D., Brands, W. R., Davis, J. R., Hunt, K., Stevens, S. J. & Gmitro, A. F., Dec 2004, In : Technology in Cancer Research and Treatment. 3, 6, p. 617-627 11 p.

Research output: Contribution to journalArticle

Open Access
64 Scopus citations

Influence of fiber optic probe geometry on the applicability of inverse models of tissue reflectance spectroscopy: Computational models and experimental measurements

Sun, J., Fu, K., Wang, A., Lin, A. W. H., Utzinger, U. & Drezek, R., Nov 1 2006, In : Applied optics. 45, 31, p. 8152-8162 11 p.

Research output: Contribution to journalArticle

25 Scopus citations

Intravital confocal and two-photon imaging of dual-color cells and extracellular matrix mimics

Bal, U., Andresen, V., Baggett, B. & Utzinger, U., Feb 1 2013, In : Microscopy and Microanalysis. 19, 1, p. 201-212 12 p.

Research output: Contribution to journalArticle

6 Scopus citations

In vitro model for endogenous optical signatures of collagen

Kirkpatrick, N. D., Hoying, J. B., Botting, S. K., Weiss, J. A. & Utzinger, U., Sep 1 2006, In : Journal of biomedical optics. 11, 5, 054021.

Research output: Contribution to journalArticle

43 Scopus citations
7 Scopus citations

In vivo time-serial multi-modality optical imaging in a mouse model of ovarian tumorigenesis

Watson, J. M., Marion, S. L., Rice, P. F., Bentley, D. L., Besselsen, D. G., Utzinger, U., Hoyer, P. B. & Barton, J. K., Jan 1 2014, In : Cancer Biology and Therapy. 15, 1, p. 42-60 19 p.

Research output: Contribution to journalArticle

14 Scopus citations

Large-scale time series microscopy of neovessel growth during angiogenesis

Utzinger, U., Baggett, B., Weiss, J. A., Hoying, J. B. & Edgar, L. T., Jul 20 2015, In : Angiogenesis. 18, 3, p. 219-232 14 p.

Research output: Contribution to journalArticle

32 Scopus citations

Live imaging of collagen remodeling during angiogenesis

Kirkpatrick, N. D., Andreou, S., Hoying, J. B. & Utzinger, U., Jun 1 2007, In : American Journal of Physiology - Heart and Circulatory Physiology. 292, 6, p. H3198-H3206

Research output: Contribution to journalArticle

64 Scopus citations

Mechanical interaction of angiogenic microvessels with the extracellular matrix

Edgar, L. T., Hoying, J. B., Utzinger, U., Underwood, C. J., Krishnan, L., Baggett, B. K., Maas, S. A., Guilkey, J. E. & Weiss, J. A., Feb 2014, In : Journal of Biomechanical Engineering. 136, 2, 021001.

Research output: Contribution to journalArticle

24 Scopus citations

Method to determine tissue fluorescence efficiency in vivo and predict signal-to-noise ratio for spectrometers

Trujillo, E. V., Sandison, D. R., Utzinger, U., Ramanujam, N., Mitchell, M. F. & Richards-Kortum, R., Jul 1998, In : Applied Spectroscopy. 52, 7, p. 943-951 9 p.

Research output: Contribution to journalArticle

20 Scopus citations

Microstructural and biomechanical alterations of the human aorta as a function of age and location

Haskett, D., Johnson, G., Zhou, A., Utzinger, U. & Vande Geest, J., Dec 2010, In : Biomechanics and Modeling in Mechanobiology. 9, 6, p. 725-736 12 p.

Research output: Contribution to journalArticle

111 Scopus citations

Microstructural differences in the human posterior sclera as a function of age and race

Yan, D., McPheeters, S., Johnson, G., Utzinger, U. & van de Geest, J. P., Feb 2011, In : Investigative Ophthalmology and Visual Science. 52, 2, p. 821-829 9 p.

Research output: Contribution to journalArticle

49 Scopus citations

Miniature endoscope for simultaneous optical coherence tomography and laser-induced fluorescence measurement

Tumlinson, A. R., Hariri, L. P., Utzinger, U. & Barton, J. K., Jan 1 2004, In : Applied optics. 43, 1, p. 113-121 9 p.

Research output: Contribution to journalArticle

117 Scopus citations

Multispectral fluorescence imaging of human ovarian and fallopian tube tissue for early-stage cancer detection

Tate, T. H., Baggett, B., Rice, P. F. S., Koevary, J. W., Orsinger, G. V., Nymeyer, A. C., Welge, W. A., Saboda, K., Roe, D., Hatch, K. D., Chambers, S. K., Utzinger, U. & Barton, J. K., May 1 2016, In : Journal of Biomedical Optics. 21, 5, 056005.

Research output: Contribution to journalArticle

16 Scopus citations