• 35785 Citations
  • 83 h-Index
1962 …2019
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Fingerprint Dive into the research topics where Victor J Hruby is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

  • 6 Similar Profiles
Melanocyte-Stimulating Hormones Medicine & Life Sciences
Peptides Medicine & Life Sciences
Opioid Receptors Medicine & Life Sciences
Ligands Medicine & Life Sciences
Oxytocin Medicine & Life Sciences
Melanocortin Receptors Medicine & Life Sciences
Opioid Analgesics Medicine & Life Sciences
D-Penicillamine (2,5)-Enkephalin Medicine & Life Sciences

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Projects 1977 2017

Melanocortins
Melanocyte-Stimulating Hormones
Ligands
Melanocortin Receptors
Peptides

Multimeric Ligands for Targeting of Melanoma

Gillies, R. J., Morse, D. & Hruby, V. J.

National Institutes of Health

7/1/025/31/14

Project: Research project

Melanoma
Ligands
Cell Surface Receptors
Receptor, Melanocortin, Type 2
Membrane Proteins
Opioid Peptides
Ligands
Pain
Opioid Analgesics
Peptidomimetics

Research Output 1962 2019

1 Citation (Scopus)

Multivalent peptide and peptidomimetic ligands for the treatment of pain without toxicities and addiction

Hruby, V. J., Jun 1 2019, In : Peptides. 116, p. 63-67 5 p.

Research output: Contribution to journalReview article

Peptidomimetics
Toxicity
Ligands
Pain
Peptides
Melanocyte-Stimulating Hormones
Lizards
Pharmaceutical Chemistry
Pigmentation
Ether

Cyclic biphalin analogues with a novel linker lead to potent agonist activities at mu, delta, and kappa opioid receptors

Remesic, M., Macedonio, G., Mollica, A., Porreca, F., Hruby, V. J. & Lee, Y. S., Jan 1 2018, (Accepted/In press) In : Bioorganic and Medicinal Chemistry.

Research output: Contribution to journalArticle

kappa Opioid Receptor
delta Opioid Receptor
mu Opioid Receptor
Opioid Receptors
hydrazine

Development of Macrocyclic Peptidomimetics Containing Constrained α,α-Dialkylated Amino Acids with Potent and Selective Activity at Human Melanocortin Receptors

Merlino, F., Zhou, Y., Cai, M., Carotenuto, A., Yousif, A. M., Brancaccio, D., Di Maro, S., Zappavigna, S., Limatola, A., Novellino, E., Grieco, P. & Hruby, V. J., May 10 2018, In : Unknown Journal. 61, 9, p. 4263-4269 7 p.

Research output: Contribution to journalArticle

Melanocortin Receptors
Melanocortins
Peptidomimetics
Human Activities
amino acids
5 Citations (Scopus)

Development of Novel Melanocortin Receptor Agonists Based on the Cyclic Peptide Framework of Sunflower Trypsin Inhibitor-1

Durek, T., Cromm, P. M., White, A. M., Schroeder, C. I., Kaas, Q., Weidmann, J., Ahmad Fuaad, A., Cheneval, O., Harvey, P. J., Daly, N. L., Zhou, Y., Dellsén, A., Österlund, T., Larsson, N., Knerr, L., Bauer, U., Kessler, H., Cai, M., Hruby, V. J., Plowright, A. T. & 1 others, Craik, D. J., Apr 26 2018, In : Journal of Medicinal Chemistry. 61, 8, p. 3674-3684 11 p.

Research output: Contribution to journalArticle

Melanocortin Receptors
Cyclic Peptides
Methylation
Peptides
Drug Design