• 1005 Citations
  • 19 h-Index
19982017
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Research Output 1998 2017

  • 1005 Citations
  • 19 h-Index
  • 40 Article
  • 10 Conference contribution
8 Citations (Scopus)

A biomimetic mechanism for antibody immobilization on lipid nanofibers for cell capture

Zha, Z., Jiang, L., Dai, Z. & Wu, X., Nov 5 2012, In : Applied Physics Letters. 101, 19, 193701.

Research output: Contribution to journalArticle

biomimetics
antibodies
immobilization
silanes
lipids
17 Citations (Scopus)

A constitutive model for protein-based materials

Wu, X., Levenston, M. E. & Chaikof, E. L., Oct 2006, In : Biomaterials. 27, 30, p. 5315-5325 11 p.

Research output: Contribution to journalArticle

Constitutive models
Proteins
Strategic materials
Tissue
Elastin
46 Citations (Scopus)

Alterations in physical cross-linking modulate mechanical properties of two-phase protein polymer networks

Wu, X., Sallach, R., Haller, C. A., Caves, J. A., Nagapudi, K., Conticello, V. P., Levenston, M. E. & Chaikof, E. L., Nov 2005, In : Biomacromolecules. 6, 6, p. 3037-3044 8 p.

Research output: Contribution to journalArticle

Polymers
Proteins
Mechanical properties
Elastin
Elastic Modulus
8 Citations (Scopus)

Anti-EGFR antibody conjugated organic-inorganic hybrid lipid nanovesicles selectively target tumor cells

Leung, S. L., Zha, Z., Cohn, C., Dai, Z. & Wu, X., Sep 1 2014, In : Colloids and Surfaces B: Biointerfaces. 121, p. 141-149 9 p.

Research output: Contribution to journalArticle

Monoclonal antibodies
antibodies
Epidermal Growth Factor Receptor
Antibodies
Lipids
39 Citations (Scopus)

A promising drug controlled-release system based on diacetylene/ phospholipid polymerized vesicles

Guo, C., Liu, S., Jiang, C., Li, W., Dai, Z., Fritz, H. & Wu, X., Nov 17 2009, In : Langmuir. 25, 22, p. 13114-13119 6 p.

Research output: Contribution to journalArticle

Phospholipids
Paclitaxel
drugs
acids
Acids
10 Citations (Scopus)

Atomic force microscopy of electrospun organic-inorganic lipid nanofibers

Zhang, J., Cohn, C., Qiu, W., Zha, Z., Dai, Z. & Wu, X., Sep 5 2011, In : Applied Physics Letters. 99, 10, 103702.

Research output: Contribution to journalArticle

lipids
atomic force microscopy
silanes
cholesterol
nanoindentation
11 Citations (Scopus)

Autoclaving as a chemical-free process to stabilize recombinant silk-elastinlike protein polymer nanofibers

Qiu, W., Cappello, J. & Wu, X., Jun 27 2011, In : Applied Physics Letters. 98, 26, 263702.

Research output: Contribution to journalArticle

autoclaving
silk
proteins
polymers
crosslinking
7 Citations (Scopus)

Centering of organic-inorganic hybrid liposomal cerasomes in electrospun gelatin nanofibers

Zha, Z., Leung, S. L., Dai, Z. & Wu, X., Jan 16 2012, In : Applied Physics Letters. 100, 3, 033702.

Research output: Contribution to journalArticle

gelatins
embedding
encapsulating
activity (biology)
aqueous solutions
36 Citations (Scopus)

Cerasomal doxorubicin with long-term storage stability and controllable sustained release

Jin, Y., Yue, X., Zhang, Q., Wu, X., Cao, Z. & Dai, Z., Sep 2012, In : Acta Biomaterialia. 8, 9, p. 3372-3380 9 p.

Research output: Contribution to journalArticle

Liposomes
Doxorubicin
Phospholipids
Lipids
Cells
2 Citations (Scopus)

Coaxial electrospinning of gelatin/polyvinyl alcohol composite nanofibers and evaluation of their material properties

Merkle, V. & Wu, X., 2012, 2012 38th Annual Northeast Bioengineering Conference, NEBEC 2012. p. 380-381 2 p. 6207123

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Polyvinyl Alcohol
Polyvinyl alcohols
Electrospinning
Gelatin
Nanofibers
3 Citations (Scopus)

Comparative study of antibody immobilization mediated by lipid and polymer fibers

Cohn, C., Leung, S. L., Zha, Z., Crosby, J., Teng, W. & Wu, X., Oct 1 2015, In : Colloids and Surfaces B: Biointerfaces. 134, p. 1-7 7 p.

Research output: Contribution to journalArticle

antibodies
immobilization
Antibodies
Immobilization
Lipids
71 Citations (Scopus)

Complete recombinant silk-elastinlike protein-based tissue scaffold

Qiu, W., Huang, Y., Teng, W., Cohn, C. M., Cappello, J. & Wu, X., Dec 13 2010, In : Biomacromolecules. 11, 12, p. 3219-3227 9 p.

Research output: Contribution to journalArticle

Tissue Scaffolds
Silk
Scaffolds
Scaffolds (biology)
Biocompatibility
22 Citations (Scopus)

Core-shell nanofibers: Integrating the bioactivity of gelatin and the mechanical property of polyvinyl alcohol

Merkle, V. M., Zeng, L., Slepian, M. J. & Wu, X., 2014, In : Biopolymers - Peptide Science Section. 101, 4, p. 336-346 11 p.

Research output: Contribution to journalArticle

Nanofibers
Polyvinyl Alcohol
Polyvinyl alcohols
Gelatin
Bioactivity
34 Citations (Scopus)

Core-shell PVA/gelatin electrospun nanofibers promote human umbilical vein endothelial cell and smooth muscle cell proliferation and migration

Merkle, V. M., Tran, P. L., Hutchinson, M., Ammann, K. R., Decook, K., Wu, X. & Slepian, M. J., Nov 1 2015, In : Acta Biomaterialia. 27, p. 77-87 11 p.

Research output: Contribution to journalArticle

Nanofibers
Polyvinyl Alcohol
Polyvinyl alcohols
Endothelial cells
Human Umbilical Vein Endothelial Cells

Deformation-induced mechanical anisotropy of gelatin films

Teng, W., Zhang, X., Merkle, V. & Wu, X., Jun 1 2016, In : Extreme Mechanics Letters. 7, p. 18-26 9 p.

Research output: Contribution to journalArticle

Trifluoroethanol
Anisotropy
Water
Glutaral
Microcracks
40 Citations (Scopus)

Deformation responses of a physically cross-linked high molecular weight elastin-like protein polymer

Wu, X., Sallach, R. E., Caves, J. M., Conticello, V. P. & Chaikof, E. L., Jul 2008, In : Biomacromolecules. 9, 7, p. 1787-1794 8 p.

Research output: Contribution to journalArticle

Elastin
Polymers
Molecular Weight
Molecular weight
Proteins

Electrospinning of recombinant protein polymer nanofibers

Qiu, W., Stokes, A., Cappello, J. & Wu, X., 2009, Proceedings of the ASME Summer Bioengineering Conference 2009, SBC2009. PART B ed. p. 1183-1184 2 p.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Electrospinning
Nanofibers
Recombinant Proteins
Polymers

Electrospun recombinant protein polymer nanofibers as a biomaterial

Qiu, W., Huang, Y., Cappello, J. & Wu, X., 2010, Proceedings of the ASME 1st Global Congress on NanoEngineering for Medicine and Biology 2010, NEMB2010. p. 207-208 2 p.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Nanofibers
Recombinant proteins
Biocompatible Materials
Recombinant Proteins
Biomaterials
7 Citations (Scopus)

Engineering aqueous fiber assembly into silk-elastin-like protein polymers

Zeng, L., Jiang, L., Teng, W., Cappello, J., Zohar, Y. & Wu, X., 2014, In : Macromolecular Rapid Communications. 35, 14, p. 1273-1279 7 p.

Research output: Contribution to journalArticle

Elastin
Silk
Nanofibers
Polymers
Proteins
17 Citations (Scopus)

Evaporation-induced assembly of biomimetic polypeptides

Keyes, J., Junkin, M., Cappello, J., Wu, X. & Wong, P. K., Jul 14 2008, In : Applied Physics Letters. 93, 2, 023120.

Research output: Contribution to journalArticle

silk
biomimetics
polypeptides
self assembly
assembly
35 Citations (Scopus)

Fabrication of gelatin nanofibrous scaffolds using ethanol/phosphate buffer saline as a benign solvent

Zha, Z., Teng, W., Markle, V., Dai, Z. & Wu, X., Dec 2012, In : Biopolymers - Peptide Science Section. 97, 12, p. 1026-1036 11 p.

Research output: Contribution to journalArticle

Gelatin
Nanofibers
Scaffolds
Buffers
Phosphates

Fabrication of genetically engineered silk-elastin-like protein polymer fibers

Qiu, W., Cappello, J. & Wu, X., 2009, Proceedings of the ASME Summer Bioengineering Conference, SBC2008. PART A ed. p. 179-180 2 p.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Elastin
Silk
Polymers
Proteins
Fabrication
16 Citations (Scopus)

Facile synthesis of Prussian blue nanoparticles as pH-responsive drug carriers for combined photothermal-chemo treatment of cancer

Chen, H., Ma, Y., Wang, X., Wu, X. & Zha, Z., 2017, In : RSC Advances. 7, 1, p. 248-255 8 p.

Research output: Contribution to journalArticle

Drug Carriers
Doxorubicin
Nanoparticles
pH effects
Oncology
18 Citations (Scopus)

Gelatin shells strengthen polyvinyl alcohol core-shell nanofibers

Merkle, V., Zeng, L., Teng, W., Slepian, M. J. & Wu, X., Oct 4 2013, In : Polymer. 54, 21, p. 6003-6007 5 p.

Research output: Contribution to journalArticle

Polyvinyl Alcohol
Polyvinyl alcohols
Gelatin
Nanofibers
Molecular orientation
27 Citations (Scopus)

Hemocompatibility of poly(vinyl alcohol)-gelatin core-shell electrospun nanofibers: A scaffold for modulating platelet deposition and activation

Merkle, V. M., Martin, D., Hutchinson, M., Tran, P. L., Behrens, A., Hossainy, S., Sheriff, J., Bluestein, D., Wu, X. & Slepian, M. J., Apr 22 2015, In : ACS Applied Materials and Interfaces. 7, 15, p. 8302-8312 11 p.

Research output: Contribution to journalArticle

Gelatin
Nanofibers
Platelets
Scaffolds
Alcohols

In vitro biocompatibility of coaxial electrospun scaffolds for cardiovascular tissue engineering

Merkle, V. M., Ammann, K. R., DeCook, K. J., Tran, P. L., Slepian, M. J. & Wu, X., 2013, ASME 2013 Summer Bioengineering Conference, SBC 2013. Vol. 1 A.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Tissue Engineering
Scaffolds (biology)
Biocompatibility
Tissue engineering
Scaffolds
12 Citations (Scopus)

In vitro evaluation and finite element simulation of drug release from polydiacetylene-polyethylene glycol stearate nanovesicles

Guo, C., Zeng, L., Liu, S., Chen, Q., Dai, Z. & Wu, X., 2012, In : Journal of Nanoscience and Nanotechnology. 12, 1, p. 245-251 7 p.

Research output: Contribution to journalArticle

Stearates
stearates
Polyethylene glycols
glycols
polyethylenes
3 Citations (Scopus)

Lipid-mediated protein functionalization of electrospun polycaprolactone fibers

Cohn, C., Leung, S. L., Crosby, J., Lafuente, B., Zha, Z., Teng, W., Downs, R. T. & Wu, X., May 1 2016, In : Express Polymer Letters. 10, 5, p. 430-437 8 p.

Research output: Contribution to journalArticle

Polycaprolactone
Silanes
Lipids
lipids
silanes

Mechanical and in-vitro cell compatibility properties of silk-elastinlike protein-based biomaterial

Teng, W., Huang, Y., Cappello, J. & Wu, X., 2010, Proceedings of the ASME 1st Global Congress on NanoEngineering for Medicine and Biology 2010, NEMB2010. p. 209-210 2 p.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Silk
Biocompatible Materials
Biomaterials
Proteins
In Vitro Techniques
10 Citations (Scopus)

Modeling the sustained release of lipophilic drugs from liposomes

Zeng, L. & Wu, X., Aug 16 2010, In : Applied Physics Letters. 97, 7, 073701.

Research output: Contribution to journalArticle

drugs
lipids
compartments
delivery
convection
28 Citations (Scopus)

Modulation of release of paclitaxel from composite cerasomes

Cao, Z., Yue, X., Jin, Y., Wu, X. & Dai, Z., Oct 1 2012, In : Colloids and Surfaces B: Biointerfaces. 98, p. 97-104 8 p.

Research output: Contribution to journalArticle

Paclitaxel
Lipids
lipids
Modulation
modulation
22 Citations (Scopus)

Nanofibrous lipid membranes capable of functionally immobilizing antibodies and capturing specific cells

Zha, Z., Cohn, C., Dai, Z., Qiu, W., Zhang, J. & Wu, X., Aug 9 2011, In : Advanced Materials. 23, 30, p. 3435-3440 6 p.

Research output: Contribution to journalArticle

Membrane Lipids
Antibodies
Silanes
Electrospinning
Antigens
13 Citations (Scopus)

Novel doxorubicin loaded PEGylated cuprous telluride nanocrystals for combined photothermal-chemo cancer treatment

Wang, X., Ma, Y., Chen, H., Wu, X., Qian, H., Yang, X. & Zha, Z., Apr 1 2017, In : Colloids and Surfaces B: Biointerfaces. 152, p. 449-458 10 p.

Research output: Contribution to journalArticle

tellurides
Oncology
Chemotherapy
Nanoparticles
Doxorubicin
17 Citations (Scopus)

One-pot glyco-affinity precipitation purification for enhanced proteomics: The flexible alignment of solution-phase capture/release and solid-phase separation

Sun, X. L., Haller, C. A., Wu, X., Conticello, V. P. & Chaikof, E. L., Nov 2005, In : Journal of Proteome Research. 4, 6, p. 2355-2359 5 p.

Research output: Contribution to journalArticle

Phase separation
Proteomics
Purification
Polymers
Carbohydrates
27 Citations (Scopus)

Optically transparent recombinant silk-elastinlike protein polymer films

Teng, W., Huang, Y., Cappello, J. & Wu, X., Feb 24 2011, In : Journal of Physical Chemistry B. 115, 7, p. 1608-1615 8 p.

Research output: Contribution to journalArticle

silk
Silk
Polymer films
proteins
Proteins
2 Citations (Scopus)

Ordering recombinant silk-elastin-like nanofibers on the microscale

Zeng, L., Teng, W., Jiang, L., Cappello, J. & Wu, X., Jan 20 2014, In : Applied Physics Letters. 104, 3, 033702.

Research output: Contribution to journalArticle

elastin
silk
microbalances
polypeptides
peptides
15 Citations (Scopus)

Organic-inorganic nanovesicles for doxorubicin storage and release

Leung, S. L., Zha, Z., Teng, W., Cohn, C., Dai, Z. & Wu, X., Jun 7 2012, In : Soft Matter. 8, 21, p. 5756-5764 9 p.

Research output: Contribution to journalArticle

serums
Doxorubicin
leakage
culture media
cells
37 Citations (Scopus)

Photomediated crosslinking of C6-cinnamate derivatized type I collagen

Dong, C. M., Wu, X., Caves, J., Rele, S. S., Thomas, B. S. & Chaikof, E. L., Jun 2005, In : Biomaterials. 26, 18, p. 4041-4049 9 p.

Research output: Contribution to journalArticle

Cinnamates
Collagen Type I
Collagen
Crosslinking
Spectrum Analysis
28 Citations (Scopus)

Physical crosslinking modulates sustained drug release from recombinant silk-elastinlike protein polymer for ophthalmic applications

Teng, W., Cappello, J. & Wu, X., Dec 10 2011, In : Journal of Controlled Release. 156, 2, p. 186-194 9 p.

Research output: Contribution to journalArticle

Silk
Polymers
Ciprofloxacin
Pharmaceutical Preparations
Proteins

Platelet activity of coaxial electrospun scaffolds for applications in cardiovascular tissue engineering

Merkle, V. M., Hutchinson, M., Tran, P. L., Sheriff, J., Bluestein, D., Wu, X. & Slepian, M. J., 2013, ASME 2013 Summer Bioengineering Conference, SBC 2013. Vol. 1 A.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Tissue Engineering
Scaffolds (biology)
Platelets
Tissue engineering
Scaffolds
89 Citations (Scopus)

Protein-based thermoplastic elastomers

Nagapudi, K., Brinkman, W. T., Leisen, J., Thomas, B. S., Wright, E. R., Haller, C., Wu, X., Apkarian, R. P., Conticello, V. P. & Chaikof, E. L., Jan 25 2005, In : Macromolecules. 38, 2, p. 345-354 10 p.

Research output: Contribution to journalArticle

Thermoplastic elastomers
Proteins
Copolymers
Recombinant proteins
Biosynthesis
47 Citations (Scopus)

Recombinant silk-elastinlike protein polymer displays elasticity comparable to elastin

Teng, W., Cappello, J. & Wu, X., Nov 9 2009, In : Biomacromolecules. 10, 11, p. 3028-3036 9 p.

Research output: Contribution to journalArticle

Elastin
Silk
Elasticity
Polymers
Proteins

Scale Dependence of Dislocation Patterns

Yang, W., Wu, X. & Yang, Q., 1998, In : Metals and Materials International. 4, 4, p. 968-972 5 p.

Research output: Contribution to journalArticle

Plastic deformation
Entropy
Metals
plastic deformation
entropy

Secondary structures and mechanical properties of biomimetic protein polymers

Teng, W., Cappello, J. & Wu, X., 2009, Proceedings of the ASME Summer Bioengineering Conference 2009, SBC2009. PART B ed. p. 797-798 2 p.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Biomimetics
Polymers
Proteins
Mechanical properties

Template-guided self-assembly of biomimetic polymers using evaporation-assisted plasma lithography

Keyes, J., Junkin, M., Cappello, J., Wu, X. & Wong, P. K., 2008, 12th International Conference on Miniaturized Systems for Chemistry and Life Sciences - The Proceedings of MicroTAS 2008 Conference. Chemical and Biological Microsystems Society, p. 236-238 3 p.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Elastin
Silk
Biomimetics
Self assembly
Lithography
12 Citations (Scopus)

The coupled effects of plastic strain gradient and thermal softening on the dynamic growth of voids

Wu, X., Ramesh, K. T. & Wright, T. W., Dec 2003, In : International Journal of Solids and Structures. 40, 24, p. 6633-6651 19 p.

Research output: Contribution to journalArticle

Strain Gradient
Softening
Voids
softening
voids
64 Citations (Scopus)

The dynamic growth of a single void in a viscoplastic material under transient hydrostatic loading

Wu, X., Ramesh, K. T. & Wright, T. W., Jan 2003, In : Journal of the Mechanics and Physics of Solids. 51, 1, p. 1-26 26 p.

Research output: Contribution to journalArticle

hydrostatics
voids
critical loading
inertia
softening
37 Citations (Scopus)

The effects of thermal softening and heat conduction on the dynamic growth of voids

Wu, X., Ramesh, K. T. & Wright, T. W., Aug 2003, In : International Journal of Solids and Structures. 40, 17, p. 4461-4478 18 p.

Research output: Contribution to journalArticle

Softening
Voids
Heat Conduction
Heat conduction
conductive heat transfer
1 Citation (Scopus)

Viscoelastic properties of genetically engineered silk-elastin-like protein polymers

Teng, W., Cappello, J. & Wu, X., 2009, Proceedings of the ASME Summer Bioengineering Conference, SBC2008. PART A ed. p. 231-232 2 p.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Elastin
Silk
Polymers
Proteins
silk-like protein polymer
67 Citations (Scopus)

Wet-spinning of recombinant silk-elastin-like protein polymer fibers with high tensile strength and high deformability

Qiu, W., Teng, W., Cappello, J. & Wu, X., Mar 9 2009, In : Biomacromolecules. 10, 3, p. 602-608 7 p.

Research output: Contribution to journalArticle

Elastin
Spinning (fibers)
Silk
Tensile Strength
Formability