Research Output 1996 2017

  • 1472 Citations
  • 18 h-Index
  • 127 Article
  • 2 Review article
  • 1 Chapter
  • 1 Comment/debate
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Article
2017

A dual therapy of off-pump temporary left ventricular extracorporeal device and amniotic stem cell for cardiogenic shock

Kazui, T., Tran, P. L., Pilikian, T. R., Marsh, K. M., Runyan, R., Konhilas, J., Smith, R. & Khalpey, Z. I. Sep 7 2017 In : Journal of Cardiothoracic Surgery. 12, 1, 80

Research output: Research - peer-reviewArticle

Cardiogenic Shock
Stem Cells
Equipment and Supplies
Therapeutics
Sternotomy

Advantages and disadvantages of using intravenous tissue Plasminogen activator as salvage therapy for inoperable HeartWare thrombosis

Basken, R., Bazzell, C. M., Smith, R., Janardhanan, R. & Khalpey, Z. Jul 1 2017 In : Journal of Cardiac Surgery. 32, 7, p. 443-446 4 p.

Research output: Research - peer-reviewArticle

Salvage Therapy
Tissue Plasminogen Activator
Thrombosis
Equipment and Supplies
Heart-Assist Devices

Anti-inflammatory properties of amniotic membrane patch following pericardiectomy for constrictive pericarditis

Marsh, K. M., Ferng, A. S., Pilikian, T., Desai, A. A., Avery, R., Friedman, M., Oliva, I., Jokerst, C., Schipper, D. & Khalpey, Z. Jan 26 2017 In : Journal of Cardiothoracic Surgery. 12, 1, 6

Research output: Research - peer-reviewArticle

Pericardiectomy
Constrictive Pericarditis
Amnion
Anti-Inflammatory Agents
Thoracic Surgery

Bifidobacterium animalis subsp. lactis 420 mitigates the pathological impact of myocardial infarction in the mouse

Danilo, C. A., Constantopoulos, E., McKee, L. A., Chen, H., Regan, J. A., Lipovka, Y., Lahtinen, S., Stenman, L. K., Nguyen, T. V. V., Doyle, K. P., Slepian, M. J., Khalpey, Z. I. & Konhilas, J. P. 2017 In : Beneficial Microbes. 8, 2, p. 257-269 13 p.

Research output: Research - peer-reviewArticle

Myocardial Infarction
Bifidobacterium animalis
Probiotics
Anti-Inflammatory Agents
Reperfusion Injury

Capsaicin-induced Ca2+ signaling is enhanced via upregulated TRPV1 channels in pulmonary artery smooth muscle cells from patients with idiopathic PAH

Song, S., Ayon, R. J., Yamamura, A., Yamamura, H., Dash, S., Babicheva, A., Tang, H., Sun, X., Cordery, A. G., Khalpey, Z., Black, S. M., Desai, A. A., Rischard, F., McDermott, K. M., Garcia, J. G. N., Makino, A. & Yuan, J. X. J. Mar 1 2017 In : American Journal of Physiology - Lung Cellular and Molecular Physiology. 312, 3, p. L309-L325

Research output: Research - peer-reviewArticle

Capsaicin
Pulmonary Artery
Smooth Muscle Myocytes
vanilloid receptor subtype 1
Familial Primary Pulmonary Hypertension

Cardiac Regeneration in the Human Left Ventricle After CorMatrix Implantation

Ferng, A., Connell, A., Nunez, M., Johnson, K., Braunhut, B., Lick, S., Desai, A., Kazui, T., Runyan, R. & Khalpey, Z. Sep 1 2017 In : Annals of Thoracic Surgery. 104, 3, p. e239-e241

Research output: Research - peer-reviewArticle

Heart Ventricles
Regeneration
Aorta
Heart-Assist Devices
Elastin

Changes in Tracheostomy- and Intubation-Related Tracheal Stenosis: Implications for Surgery

Kim, S. S., Khalpey, Z., Hsu, C. & Little, A. G. 2017 (Accepted/In press) In : Annals of Thoracic Surgery.

Research output: Research - peer-reviewArticle

Tracheal Stenosis
Tracheostomy
Intubation
Pathologic Constriction
Kaplan-Meier Estimate
1 Citations

Chronic Myocardial Ischemia Leads to Loss of Maximal Oxygen Consumption and Complex I Dysfunction

Schipper, D. A., Palsma, R., Marsh, K. M., O'Hare, C., Dicken, D. S., Lick, S., Kazui, T., Johnson, K., Smolenski, R. T., Duncker, D. J. & Khalpey, Z. 2017 (Accepted/In press) In : Annals of Thoracic Surgery.

Research output: Research - peer-reviewArticle

Oxygen Consumption
Myocardial Ischemia
Respiration
Ischemia
Atrial Appendage

Deletion of CD73 in mice leads to aortic valve dysfunction

Zukowska, P., Kutryb-Zajac, B., Jasztal, A., Toczek, M., Zabielska, M., Borkowski, T., Khalpey, Z., Smolenski, R. T. & Slominska, E. M. Jun 1 2017 In : Biochimica et Biophysica Acta - Molecular Basis of Disease. 1863, 6, p. 1464-1472 9 p.

Research output: Research - peer-reviewArticle

High Fat Diet
Aortic Valve
Adenosine
Alkaline Phosphatase
Diet

Improved metabolism and redox state with a novel preservation solution: Implications for donor lungs after cardiac death (DCD)

Schipper, D. A., Louis, A. V., Dicken, D. S., Johnson, K., Smolenski, R. T., Black, S. M., Runyan, R., Konhilas, J., Garcia, J. G. N. & Khalpey, Z. 2017 In : Pulmonary Circulation. 7, 2, p. 494-504 11 p.

Research output: Research - peer-reviewArticle

Oxidation-Reduction
Lung
Somah
Dextrans
Potassium

Intracranial Hemorrhage in Patients with Durable Mechanical Circulatory Support Devices: Institutional Review and Proposed Treatment Algorithm

Ramey, W. L., Basken, R. L., Walter, C. M., Khalpey, Z., Lemole, G. M. & Dumont, T. M. Dec 1 2017 In : World Neurosurgery. 108, p. 826-835 10 p.

Research output: Research - peer-reviewArticle

Intracranial Hemorrhages
Equipment and Supplies
Therapeutics
Heart-Assist Devices
Artificial Heart

Metabolic Impact of Rapamycin (Sirolimus) and B-Estradiol Using Mouse Embryonic Fibroblasts as a Model for Lymphangioleiomyomatosis

Marsh, K. M., Schipper, D., Ferng, A. S., Johnson, K., Fisher, J., Knapp, S., Dicken, D. & Khalpey, Z. Jun 2 2017 (Accepted/In press) In : Lung. p. 1-6 6 p.

Research output: Research - peer-reviewArticle

Lymphangioleiomyomatosis
Sirolimus
Estradiol
Fibroblasts
Oxygen Consumption

Minimally invasive insertion of off-pump central extracorporeal membrane oxygenation

Avery, R., Yu, S., Rao, P., Wong, R. & Khalpey, Z. 2017 (Accepted/In press) In : Journal of Cardiac Surgery.

Research output: Research - peer-reviewArticle

1 Citations

Novel vs clinical organ preservation solutions: Improved cardiac mitochondrial protection

Ferng, A. S., Schipper, D., Connell, A. M., Marsh, K. M., Knapp, S. & Khalpey, Z. Jan 26 2017 In : Journal of Cardiothoracic Surgery. 12, 1, 7

Research output: Research - peer-reviewArticle

Organ Preservation Solutions
Somah
Perfadex
Celsior
Oxygen Consumption
1 Citations

Off-pump left ventricular assist device exchange via re-do left mini-thoracotomy with original outflow graft preservation

Iwanski, J., Tran, P. L., Jerman, C., Smith, R., Kazui, T. & Khalpey, Z. 2017 In : Perfusion (United Kingdom). 32, 3, p. 179-182 4 p.

Research output: Research - peer-reviewArticle

Heart-Assist Devices
Thoracotomy
Transplants
Left ventricular assist devices
Grafts

Real-Time Autofluorescence Imaging to Diagnose LVAD Driveline Infections

Keenan, J. B., Rajab, T. K., Armstrong, D. G. & Khalpey, Z. Jun 1 2017 In : Annals of Thoracic Surgery. 103, 6, p. e493-e495

Research output: Research - peer-reviewArticle

Optical Imaging
Wounds and Injuries
Infection
Asymptomatic Infections
Heart-Assist Devices
First-Pass Ventriculography
Heart-Assist Devices
Heart Failure
Stroke Volume
Radionuclide Angiography

Tissue Expander as a Routine Component of 5

Avery, R., Paidy, S. R., Keller, R., Lick, S., Smith, R. G. & Khalpey, Z. Jan 1 2017 In : Circulation: Heart Failure. 10, 1, e003765

Research output: Research - peer-reviewArticle

Translation of First North American 50 and 70 cc Total Artificial Heart Virtual and Clinical Implantations: Utility of 3D Computed Tomography to Test Fit Devices

Ferng, A. S., Oliva, I., Jokerst, C., Avery, R., Connell, A. M., Tran, P. L., Smith, R. G. & Khalpey, Z. Aug 1 2017 In : Artificial Organs. 41, 8, p. 727-734 8 p.

Research output: Research - peer-reviewArticle

Artificial Heart
Tomography
Equipment and Supplies
Artificial heart
Thorax
2016

Adipose-derived human stem/stromal cells: comparative organ specific mitochondrial bioenergy profiles

Ferng, A. S., Marsh, K. M., Fleming, J. M., Conway, R. F., Schipper, D., Bajaj, N., Connell, A. M., Pilikian, T., Johnson, K., Runyan, R., Black, S. M., Szivek, J. A. & Khalpey, Z. Dec 1 2016 In : SpringerPlus. 5, 1, 2057

Research output: Research - peer-reviewArticle

Stromal Cells
Stem Cells
Energy Metabolism
Adipose Tissue
Respiration
1 Citations
Heart-Assist Devices
Aortic Valve Insufficiency
Aortic Valve
Transplants
Dilated Cardiomyopathy
3 Citations

A novel minimally invasive off-pump biventricular assist device insertion technique

Khalpey, Z., Smith, R., Echeverria, A., Le Tran, P. & Kazui, T. Jan 1 2016 In : Journal of Thoracic and Cardiovascular Surgery. 151, 1, p. e5-e7

Research output: Research - peer-reviewArticle

Aortic valve replacement for Libman-Sacks endocarditis

Keenan, J. B., Janardhanan, R., Larsen, B. T. & Khalpey, Z. 2016 In : BMJ Case Reports. 2016, 215914

Research output: Research - peer-reviewArticle

Endocarditis
Aortic Valve
Non-Infective Endocarditis
Embolectomy
Lupus Nephritis

A Physical Heart Failure Simulation System Utilizing the Total Artificial Heart and Modified Donovan Mock Circulation

Crosby, J. R., Decook, K. J., Tran, P. L., Betterton, E., Smith, R. G., Larson, D. F., Khalpey, Z. I., Burkhoff, D. & Slepian, M. J. 2016 (Accepted/In press) In : Artificial Organs.

Research output: Research - peer-reviewArticle

Artificial Heart
Starlings
Heart Failure
Hemodynamics
Equipment and Supplies
1 Citations

Associations of prolonged QTc in sickle cell disease

Indik, J. H., Nair, V., Rafikov, R., Nyotowidjojo, I. S., Bisla, J., Kansal, M., Parikh, D. S., Robinson, M., Desai, A., Oberoi, M., Gupta, A., Abbasi, T., Khalpey, Z., Patel, A. R., Lang, R. M., Dudley, S. C., Choi, B. R., Garcia, J. G. N., Machado, R. F. & Desai, A. A. Oct 1 2016 In : PLoS ONE. 11, 10, e0164526

Research output: Research - peer-reviewArticle

Sickle Cell Anemia
Mortality
sickle cell anemia
Hazards
Electrocardiography
1 Citations

First North American 50cc Total Artificial Heart Experience: Conversion from a 70cc Total Artificial Heart

Khalpey, Z., Kazui, T., Ferng, A. S., Connell, A., Tran, P. L. L., Meyer, M., Rawashdeh, B., Smith, R. G., Sweitzer, N. K., Friedman, M., Lick, S., Slepian, M. J. J. & Copeland, J. G. G. Jan 20 2016 (Accepted/In press) In : ASAIO Journal.

Research output: Research - peer-reviewArticle

Artificial Heart
Artificial heart
Thorax
Veins
Transplants

Hemolysate-mediated platelet aggregation: An additional risk mechanism contributing to thrombosis of continuous flow ventricular assist devices

Tran, P. L., Pietropaolo, M. G., Valerio, L., Brengle, W., Wong, R. K., Kazui, T., Khalpey, Z. I., Redaelli, A., Sheriff, J., Bluestein, D. & Slepian, M. J. Jul 1 2016 In : Perfusion (United Kingdom). 31, 5, p. 401-408 8 p.

Research output: Research - peer-reviewArticle

Platelets
Blood
Agglomeration
Heart-Assist Devices
Hemolysis
3 Citations

Minimally invasive approach for percutaneous CentriMag right ventricular assist device support using a single PROTEKDuo Cannula

Kazui, T., Tran, P. L., Echeverria, A., Jerman, C. F., Iwanski, J., Kim, S. S., Smith, R. G. & Khalpey, Z. I. Aug 4 2016 In : Journal of Cardiothoracic Surgery. 11, 1, 123

Research output: Research - peer-reviewArticle

Heart-Assist Devices
Cannula
Jugular Veins
Heart Atria
Pulmonary Artery

Minimally Invasive Implantation: The Procedure of Choice!

Schmitto, J. D., Deniz, E., Rojas, S. V., Maltais, S., Khalpey, Z., Hanke, J. S., Egger, C. & Haverich, A. Feb 1 2016 In : Operative Techniques in Thoracic and Cardiovascular Surgery. 21, 1, p. 65-78 14 p.

Research output: Research - peer-reviewArticle

Heart-Assist Devices
Minimally Invasive Surgical Procedures
Length of Stay
Survival Rate
Heart Failure
2 Citations

Nineteen-Millimeter Bioprosthetic Aortic Valves Are Safe and Effective for Elderly Patients With Aortic Stenosis

Khalpey, Z., Myers, P. O., McGurk, S., Schmitto, J. D., Nauta, F., Borstlap, W., Wiegerinck, E., Wu, J. & Cohn, L. H. Feb 1 2016 In : Annals of Thoracic Surgery. 101, 2, p. 650-657 8 p.

Research output: Research - peer-reviewArticle

Aortic Valve Stenosis
Aortic Valve
Prostheses and Implants
Mortality
Bioprosthesis

Novel method using rotational thromboelastography analysis for intraoperative management of device patient with heparin-induced thrombocytopenia

Iwanski, J., Kazui, T., Le Tran, P., Basken, R., Wong, R. K. & Khalpey, Z. Jan 11 2016 (Accepted/In press) In : Blood Coagulation and Fibrinolysis.

Research output: Research - peer-reviewArticle

Thrombelastography
Thrombocytopenia
Heparin
Equipment and Supplies
Thrombosis
2 Citations

Nucleotide Catabolism on the Surface of Aortic Valve Xenografts; Effects of Different Decellularization Strategies

Kutryb-Zajac, B., Yuen, A. H. Y., Khalpey, Z., Zukowska, P., Slominska, E. M., Taylor, P. M., Goldstein, S., Heacox, A. E., Lavitrano, M., Chester, A. H., Yacoub, M. H. & Smolenski, R. T. Apr 1 2016 In : Journal of Cardiovascular Translational Research. 9, 2, p. 119-126 8 p.

Research output: Research - peer-reviewArticle

Deamination
Adenosine Monophosphate
Aortic Valve
Heterografts
Adenosine
12 Citations

Pathogenic role of calcium-sensing receptors in the development and progression of pulmonary hypertension

Tang, H., Yamamura, A., Yamamura, H., Song, S., Fraidenburg, D. R., Chen, J., Gu, Y., Pohl, N. M., Zhou, T., Jiménez-Pérez, L., Ayon, R. J., Desai, A. A., Goltzman, D., Rischard, F., Khalpey, Z., Black, S. M., Garcia, J. G. N., Makino, A. & Yuan, J. X. J. Mar 1 2016 In : American Journal of Physiology - Lung Cellular and Molecular Physiology. 310, 9, p. L846-L859

Research output: Research - peer-reviewArticle

Calcium-Sensing Receptors
Pulmonary Hypertension
Lung
Smooth Muscle Myocytes
Familial Primary Pulmonary Hypertension
2 Citations

The Critical Role of Bioenergetics in Donor Cardiac Allograft Preservation

Schipper, D. A., Marsh, K. M., Ferng, A. S., Duncker, D. J., Laman, J. D. & Khalpey, Z. Jun 1 2016 In : Journal of Cardiovascular Translational Research. 9, 3, p. 176-183 8 p.

Research output: Research - peer-reviewArticle

Reperfusion Injury
Energy Metabolism
Allografts
Organ Preservation
Reactive Oxygen Species

Total Artificial Heart, Augmented by Veno-Venous Extracorporeal Membrane Oxygenation.

Lick, S. D., Tran, P. L., Kazui, T., Smith, R. G. & Khalpey, Z. I. Jan 13 2016 (Accepted/In press) In : ASAIO Journal.

Research output: Research - peer-reviewArticle

Artificial Heart
Extracorporeal Membrane Oxygenation
Membranes
Artificial heart
Oxygenation
2015

Case Report: Disparate flow in HeartMate II patient with extensive left ventricle repair

Tran, P. L., Kazui, T., Perovic, V., Mikail, P., Lick, S., Smith, R., Betterton, E. W., Venkat, R., Iwanski, J., Wong, R. K., Slepian, M. J. & Khalpey, Z. 2015 In : Perfusion. 31, 4, p. 349-352 4 p.

Research output: Research - peer-reviewArticle

Left ventricular assist devices
Catheters
Repair
Flow rate
Defects
6 Citations

Complex I dysfunction underlies the glycolytic switch in pulmonary hypertensive smooth muscle cells

Rafikov, R., Sun, X., Rafikova, O., Louise Meadows, M., Desai, A. A., Khalpey, Z., Yuan, J. X. J., Fineman, J. R. & Black, S. M. Dec 1 2015 In : Redox Biology. 6, p. 278-286 9 p.

Research output: Research - peer-reviewArticle

Muscle
Cells
Switches
Glycolysis
Pulmonary Hypertension
6 Citations

Diet and sex modify exercise and cardiac adaptation in the mouse

Konhilas, J. P., Chen, H., Luczak, E., McKee, L. A., Regan, J., Watson, P. A., Stauffer, B. L., Khalpey, Z. I., McKinsey, T. A., Horn, T., Lafleur, B. & Leinwand, L. A. 2015 In : American Journal of Physiology - Heart and Circulatory Physiology. 308, 2, p. H135-H145

Research output: Research - peer-reviewArticle

Diet
Genes
Cardiomegaly
Caseins
Transforming Growth Factors
2 Citations

Factors in the Selection and Management of Chest Tubes After Pulmonary Lobectomy: Results of a National Survey of Thoracic Surgeons

Kim, S. S., Khalpey, Z., Daugherty, S. L., Torabi, M. & Little, A. G. 2015 (Accepted/In press) In : Annals of Thoracic Surgery.

Research output: Research - peer-reviewArticle

Chest Tubes
Thorax
Lung
Surveys and Questionnaires
Surgeons
2 Citations

First in man: Amniotic patch reduces postoperative inflammation

Khalpey, Z., Marsh, K. M., Ferng, A., Riaz, I. B., Friedman, M., Indik, J., Avery, R., Jokerst, C. & Oliva, I. 2015 In : American Journal of Medicine. 128, 1, p. e5-e6

Research output: Research - peer-reviewArticle

2 Citations

First in man: Sternal reconstruction with autologous stem cells

Khalpey, Z., Marsh, K. M., Ferng, A., Riaz, I. B., Hemphill, C., Johnson, K., Oliva, I. & Friedman, M. Oct 1 2015 In : ASAIO Journal. 61, 5, p. e31-e32

Research output: Research - peer-reviewArticle

Blood Vessels
Stem Cells
Stem cells
Plating
Bone
23 Citations

In-hospital outcomes of a minimally invasive off-pump left thoracotomy approach using a centrifugal continuous-flow left ventricular assist device

Sileshi, B., Haglund, N. A., Davis, M. E., Tricarico, N. M., Stulak, J. M., Khalpey, Z., Danter, M. R., Deegan, R., Kennedy, J., Keebler, M. E. & Maltais, S. Jan 1 2015 In : Journal of Heart and Lung Transplantation. 34, 1, p. 107-112 6 p.

Research output: Research - peer-reviewArticle

Heart-Assist Devices
Thoracotomy
Length of Stay
Propensity Score
Sternotomy
4 Citations

LKB1/Mo25/STRAD uniquely impacts sarcomeric contractile function and posttranslational modification

Behunin, S. M., Lopez-Pier, M. A., Birch, C. L., McKee, L. A. K., Danilo, C., Khalpey, Z. & Konhilas, J. P. Mar 24 2015 In : Biophysical Journal. 108, 6, p. 1484-1494 11 p.

Research output: Research - peer-reviewArticle

AMP-Activated Protein Kinases
Post Translational Protein Processing
Phosphotransferases
Liver
Proteins
12 Citations

Minimally Invasive Ventricular Assist Device Surgery

Rojas, S. V., Avsar, M., Hanke, J. S., Khalpey, Z., Maltais, S., Haverich, A. & Schmitto, J. D. Jun 1 2015 In : Artificial Organs. 39, 6, p. 473-479 7 p.

Research output: Research - peer-reviewArticle

Heart-Assist Devices
Left ventricular assist devices
Surgery
Minimally Invasive Surgical Procedures
Miniaturization
3 Citations

Mitral valve repair versus replacement for ischemic mitral regurgitation: Controversy remains alive - Letter 2

Díaz, R., Hernandez-Vaquero, D., Khalpey, Z. & Morís, C. Apr 1 2015 In : Annals of Thoracic Surgery. 99, 4, p. 1490 1 p.

Research output: Research - peer-reviewArticle

2 Citations

Organ transplantation in China: Concerns remain

Trey, T., Sharif, A., Singh, M. F., Khalpey, Z. & Caplan, A. L. Mar 7 2015 In : The Lancet. 385, 9971, p. 854 1 p.

Research output: Research - peer-reviewArticle

1 Citations

Pediatric secondary chronic myeloid leukemia following cardiac transplantation for anthracycline-induced cardiomyopathy

Menon, N. M., Katsanis, E., Khalpey, Z. & Whitlow, P. Jan 1 2015 In : Pediatric Blood and Cancer. 62, 1, p. 166-168 3 p.

Research output: Research - peer-reviewArticle

Anthracyclines
Heart Transplantation
Leukemia, Myelogenous, Chronic, BCR-ABL Positive
Cardiomyopathies
Pediatrics
8 Citations

Physiological characterization of the SynCardia total artificial heart in a mock circulation system

Crosby, J. R., Decook, K. J., Tran, P. L., Smith, R. G., Larson, D. F., Khalpey, Z. I., Burkhoff, D. & Slepian, M. J. Jul 20 2015 In : ASAIO Journal. 61, 3, p. 274-281 8 p.

Research output: Research - peer-reviewArticle

Artificial Heart
Artificial heart
Pressure
Starlings
Cardiovascular System
3 Citations

Rapid porcine lung decellularization using a novel organ regenerative control acquisition bioreactor

Khalpey, Z., Qu, N., Hemphill, C., Louis, A. V., Ferng, A. S., Son, T. G., Stavoe, K., Penick, K., Tran, P. L., Konhilas, J., Lagrand, D. S. & Garcia, J. G. N. Jan 13 2015 In : ASAIO Journal. 61, 1, p. 71-77 7 p.

Research output: Research - peer-reviewArticle

Hematoxylin
Eosine Yellowish-(YS)
Bioreactors
Transmission electron microscopy
Scanning electron microscopy
2 Citations

Robotic left ventricular assist device implantation using left thoracotomy approach in patients with previous sternotomies

Khalpey, Z., Riaz, I. B., Marsh, K. M., Ansari, M. Z. A., Bilal, J., Cooper, A., Paidy, S., Schmitto, J. D., Smith, R., Friedman, M., Slepian, M. J. & Poston, R. Nov 3 2015 In : ASAIO Journal. 61, 6, p. e44-e46

Research output: Research - peer-reviewArticle

Heart-Assist Devices
Sternotomy
Robotics
Thoracotomy
Left ventricular assist devices