CHEMOPREVENTION OF SKIN CANCER BY VITAMIN A: A K SUBJEC

Project: Research project

Description

The overall objective of this proposal is to continue the ongoing
Clinical Trial to compare the efficacy of Vitamin A (Retinol)
versus a placebo in the prevention of basal cell carcinoma or
cutaneous squamous cell carcinoma in participants diagnosed to
have multiple actinic keratoses. Our research plan involves a multidisciplinary cancer research
effort with the following specific aims: 1) To compare the incidence, frequency and time to
development of subsequent basal or squamous cell skin
cancers,
2) to measure the incidence, frequency and time to
development of other cancers,
3) To determine the frequency of and motivate protocol
compliance,
4) To determine the incidence, frequency, type and degree of
toxicity.
StatusFinished
Effective start/end date9/25/8311/30/93

Funding

  • National Institutes of Health
  • National Institutes of Health

Fingerprint

Actinic Keratosis
Vitamin A
Pharmacology
Incidence
Basal Cell Carcinoma
Squamous Cell Carcinoma
Neoplasms
Epithelial Cells
Placebos
Research

ASJC

  • Medicine(all)