Abstract
A 5-endo trig oxidative radical cyclization of benzylamine-derived Ugi three-component reaction products rapidly affords imidazolidinones with three diversity elements. This adaptation of our previously described multicomponent reaction-oxidation methodology further showcases manipulation of the diversity elements in multicomponent reaction products via oxidative radical cyclizations, which generates highly decorated privileged heterocycles.
Original language | English (US) |
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Pages (from-to) | 107-112 |
Number of pages | 6 |
Journal | Organic Letters |
Volume | 23 |
Issue number | 1 |
DOIs | |
State | Published - Jan 1 2021 |
ASJC Scopus subject areas
- Biochemistry
- Physical and Theoretical Chemistry
- Organic Chemistry