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  • Irving L Kron
2019

Adenosine 2A Receptor Activation Attenuates Ischemia Reperfusion Injury During Extracorporeal Cardiopulmonary Resuscitation

Mehaffey, J. H., Money, D., Charles, E. J., Schubert, S., Piñeros, A. F., Wu, D., Bontha, S. V., Hawkins, R., Teman, N. R., Laubach, V. E., Mas, V. R., Tribble, C. G., Maluf, D. G., Sharma, A. K., Yang, Z., Kron, I. L. & Roeser, M. E., Jun 1 2019, In : Annals of surgery. 269, 6, p. 1176-1183 8 p.

Research output: Contribution to journalArticle

3 Scopus citations

A focused approach: Specialization in coronary revascularization

Chancellor, W. Z. & Kron, I. L., Mar 2019, In : Journal of Thoracic and Cardiovascular Surgery. 157, 3, p. 948-949 2 p.

Research output: Contribution to journalEditorial

Open Access

Biatrial maze procedure versus pulmonary vein isolation for atrial fibrillation during mitral valve surgery: New analytical approaches and end points

Cardiothoracic Surgical Trials Network Investigators, Jan 2019, In : Journal of Thoracic and Cardiovascular Surgery. 157, 1, p. 234-243.e9

Research output: Contribution to journalArticle

Open Access
7 Scopus citations

Can lung transplant surgeons still be scientists? High productivity despite competitive funding

Narahari, A. K., Charles, E. J., Hunter Mehaffey, J., Hawkins, R. B., Sharma, A. K., Laubach, V. E., Tribble, C. G. & Kron, I. L., Jan 2019, In : Heart Surgery Forum. 22, 1, p. E1-E7

Research output: Contribution to journalArticle

Open Access
2 Scopus citations

Cost-effectiveness of coronary artery bypass grafting plus mitral valve repair versus coronary artery bypass grafting alone for moderate ischemic mitral regurgitation

Cardiothoracic Surgical Trials Network Investigators, Jan 1 2019, (Accepted/In press) In : Journal of Thoracic and Cardiovascular Surgery.

Research output: Contribution to journalArticle

2 Scopus citations

Determining which prosthetic to use during aortic valve replacement in patients aged younger than 70 years: A systematic review of the literature

Borger, P., Charles, E. J., Smith, E. D., Hunter Mehaffey, J., Hawkins, R. B., Kron, I. L., Ailawadi, G. & Teman, N., Jan 1 2019, In : Heart Surgery Forum. 22, 2, p. E70-E81

Research output: Contribution to journalArticle

1 Scopus citations

Development and Validation of Procedure-Specific Risk Score for Predicting Postoperative Pulmonary Complication: A NSQIP Analysis

Foster, C. A., Charles, E. J., Turrentine, F. E., Sohn, M. W., Kron, I. L. & Jones, R. S., Oct 2019, In : Journal of the American College of Surgeons. 229, 4, p. 355-365.e3

Research output: Contribution to journalArticle

1 Scopus citations

One-Year Outcomes after MitraClip for Functional Mitral Regurgitation

Ailawadi, G., Lim, D. S., Mack, M. J., Trento, A., Kar, S., Grayburn, P. A., Glower, D. D., Wang, A., Foster, E., Qasim, A., Weissman, N. J., Ellis, J., Crosson, L., Fan, F., Kron, I. L., Pearson, P. J. & Feldman, T., Jan 2 2019, In : Circulation. 139, 1, p. 37-47 11 p.

Research output: Contribution to journalArticle

Open Access
16 Scopus citations

Outcomes of left main revascularization in patients with acute coronary syndromes and stable ischemic heart disease: Analysis from the EXCEL trial

Doucet, S., Jolicœur, E. M., Serruys, P. W., Ragosta, M., Kron, I. L., Scholtz, W., Börgermann, J., Zhang, Y., McAndrew, T., Sabik, J. F., Kappetein, A. P. & Stone, G. W., Aug 2019, In : American Heart Journal. 214, p. 9-17 9 p.

Research output: Contribution to journalArticle

2 Scopus citations

Pacemaker Implantation After Mitral Valve Surgery With Atrial Fibrillation Ablation

CTSN Investigators, May 21 2019, In : Journal of the American College of Cardiology. 73, 19, p. 2427-2435 9 p.

Research output: Contribution to journalArticle

2 Scopus citations

Preoperative β-blocker use correlates with worse outcomes in patients undergoing aortic valve replacement

Schubert, S. A., Hawkins, R. B., Mehaffey, J. H., Fonner, C. E., Rich, J. B., Speir, A. M., Quader, M., Kron, I. L., Yarboro, L. T. & Ailawadi, G., Dec 2019, In : Journal of Thoracic and Cardiovascular Surgery. 158, 6, p. 1589-1597.e3

Research output: Contribution to journalArticle

10 Scopus citations

Pulsed ultrasound attenuates the hyperglycemic exacerbation of myocardial ischemia–reperfusion injury

Charles, E. J., Tian, Y., Zhang, A., Wu, D., Mehaffey, J. H., Gigliotti, J. C., Klibanov, A. L., Kron, I. L. & Yang, Z., Jan 1 2019, (Accepted/In press) In : Journal of Thoracic and Cardiovascular Surgery.

Research output: Contribution to journalArticle

2 Scopus citations

Socioeconomic Distressed Communities Index Predicts Risk-Adjusted Mortality After Cardiac Surgery

Investigators for the Virginia Cardiac Services Quality Initiative, Jun 2019, In : Annals of Thoracic Surgery. 107, 6, p. 1706-1712 7 p.

Research output: Contribution to journalArticle

3 Scopus citations

The myocardial infarct-exacerbating effect of cell-free DNA is mediated by the high-mobility group box 1–receptor for advanced glycation end products–Toll-like receptor 9 pathway

Tian, Y., Charles, E. J., Yan, Z., Wu, D., French, B. A., Kron, I. L. & Yang, Z., Jun 2019, In : Journal of Thoracic and Cardiovascular Surgery. 157, 6, p. 2256-2269.e3

Research output: Contribution to journalArticle

Open Access
6 Scopus citations

Travel distance and regional access to cardiac valve surgery

Hawkins, R. B., Byler, M., Fonner, C., Kron, I. L., Yarboro, L. T., Speir, A. M., Quader, M. A., Ailawadi, G. & Mehaffey, J. H., Oct 1 2019, In : Journal of Cardiac Surgery. 34, 10, p. 1044-1048 5 p.

Research output: Contribution to journalArticle

2018

Amiodarone Protocol Provides Cost-Effective Reduction in Postoperative Atrial Fibrillation

Mehaffey, J. H., Hawkins, R. B., Byler, M., Smith, J., Kern, J. A., Kron, I., Ailawadi, G., Wanchek, T. & Yarboro, L. T., Jun 2018, In : Annals of Thoracic Surgery. 105, 6, p. 1697-1702 6 p.

Research output: Contribution to journalArticle

Open Access
7 Scopus citations

Bedside-to-Bench and Back Again: Surgeon-Initiated Translational Research

Charles, E. J. & Kron, I. L., Jan 2018, In : Annals of Thoracic Surgery. 105, 1, p. 10-11 2 p.

Research output: Contribution to journalEditorial

Open Access

Cardiothoracic and Vascular Surgeons Achieve High Rates of K Award Conversion Into R01 Funding

Narahari, A. K., Mehaffey, J. H., Hawkins, R. B., Baderdinni, P. K., Chandrabhatla, A. S., Tribble, C. G., Kron, I. L., Roeser, M. E., Walters, D. M. & Ailawadi, G., Aug 2018, In : Annals of Thoracic Surgery. 106, 2, p. 602-607 6 p.

Research output: Contribution to journalArticle

Open Access
3 Scopus citations

Cardiothoracic surgery training grants provide protected research time vital to the development of academic surgeons

Narahari, A. K., Charles, E. J., Mehaffey, J. H., Hawkins, R. B., Schubert, S. A., Tribble, C. G., Schuessler, R. B., Damiano, R. J. & Kron, I. L., May 2018, In : Journal of Thoracic and Cardiovascular Surgery. 155, 5, p. 2050-2056 7 p.

Research output: Contribution to journalArticle

7 Scopus citations

Cardiovascular monitoring and support

Charles, E. J. & Kron, I. L., Jan 1 2018, Fischer's Mastery of Surgery, Seventh Edition. Wolters Kluwer Health Adis (ESP), Vol. 1. p. 68-84 17 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Contemporary outcomes in reoperative mitral valve surgery

Mehaffey, H. J., Hawkins, R. B., Schubert, S., Fonner, C., Yarboro, L. T., Quader, M., Speir, A., Rich, J., Kron, I. L. & Ailawadi, G., Apr 2018, In : Heart. 104, 8, p. 652-656 5 p.

Research output: Contribution to journalArticle

14 Scopus citations

Coronary artery bypass grafting bundled payment proposal will have significant financial impact on hospitals

Investigators for the Virginia Cardiac Services Quality Initiative, Jan 2018, In : Journal of Thoracic and Cardiovascular Surgery. 155, 1, p. 182-188 7 p.

Research output: Contribution to journalArticle

15 Scopus citations

Cost of individual complications following coronary artery bypass grafting

Virginia Cardiac Services Quality Initiative, Mar 2018, In : Journal of Thoracic and Cardiovascular Surgery. 155, 3, p. 875-882.e1

Research output: Contribution to journalArticle

19 Scopus citations

Development of a Risk Prediction Model and Clinical Risk Score for Isolated Tricuspid Valve Surgery

Investigators for the Virginia Cardiac Surgery Quality Initiative and the Michigan Society of Thoracic and Cardiovascular Surgeons, Jul 2018, In : Annals of Thoracic Surgery. 106, 1, p. 129-136 8 p.

Research output: Contribution to journalArticle

11 Scopus citations

Does Preoperative Troponin Level Impact Outcomes After Coronary Artery Bypass Grafting?

Beller, J. P., Hawkins, R. B., Mehaffey, J. H., LaPar, D. J., Kron, I. L., Yarboro, L. T., Ailawadi, G. & Ghanta, R. K., Jul 2018, In : Annals of Thoracic Surgery. 106, 1, p. 46-51 6 p.

Research output: Contribution to journalArticle

4 Scopus citations

Expanding the donor lung pool: how many donations after circulatory death organs are we missing?

Chancellor, W. Z., Charles, E. J., Mehaffey, J. H., Hawkins, R. B., Foster, C. A., Sharma, A. K., Laubach, V. E., Kron, I. L. & Tribble, C. G., Mar 2018, In : Journal of Surgical Research. 223, p. 58-63 6 p.

Research output: Contribution to journalArticle

3 Scopus citations

Ex vivo assessment of porcine donation after circulatory death lungs that undergo increasing Warm Ischemia times

Charles, E. J., Mehaffey, J. H., Huerter, M. E., Sharma, A. K., Stoler, M. H., Roeser, M. E., Walters, D. M., Tribble, C. G., Kron, I. L. & Laubach, V. E., Dec 2018, In : Transplantation Direct. 4, 12, e405.

Research output: Contribution to journalArticle

Open Access
3 Scopus citations

Increasing circulating sphingosine-1-phosphate attenuates lung injury during ex vivo lung perfusion

Mehaffey, J. H., Charles, E. J., Narahari, A. K., Schubert, S., Laubach, V. E., Teman, N. R., Lynch, K. R., Kron, I. L. & Sharma, A. K., Aug 2018, In : Journal of Thoracic and Cardiovascular Surgery. 156, 2, p. 910-917 8 p.

Research output: Contribution to journalArticle

6 Scopus citations

Infarct-sparing effect of adenosine A2B receptor agonist is primarily due to its action on splenic leukocytes via a PI3K/Akt/IL-10 pathway

Ni, Y., Liang, D., Tian, Y., Kron, I. L., French, B. A. & Yang, Z., Dec 2018, In : Journal of Surgical Research. 232, p. 442-449 8 p.

Research output: Contribution to journalArticle

4 Scopus citations

In vivo lung perfusion rehabilitates sepsis-induced lung injury

Mehaffey, J. H., Charles, E. J., Schubert, S., Salmon, M., Sharma, A. K., Money, D., Stoler, M. H., Laubach, V. E., Tribble, C. G., Roeser, M. E. & Kron, I. L., Jan 2018, In : Journal of Thoracic and Cardiovascular Surgery. 155, 1, p. 440-448.e2

Research output: Contribution to journalArticle

3 Scopus citations

Left Main Revascularization With PCI or CABG in Patients With Chronic Kidney Disease: EXCEL Trial

Giustino, G., Mehran, R., Serruys, P. W., Sabik, J. F., Milojevic, M., Simonton, C. A., Puskas, J. D., Kandzari, D. E., Morice, M. C., Taggart, D. P., Gershlick, A. H., Généreux, P., Zhang, Z., McAndrew, T., Redfors, B., Ragosta, M., Kron, I. L., Dressler, O., Leon, M. B., Pocock, S. J. & 3 others, Ben-Yehuda, O., Kappetein, A. P. & Stone, G. W., Aug 14 2018, In : Journal of the American College of Cardiology. 72, 7, p. 754-765 12 p.

Research output: Contribution to journalArticle

Open Access
12 Scopus citations

Loss of Medicaid insurance after successful bariatric surgery: an unintended outcome

Mehaffey, J. H., Charles, E. J., Kron, I. L., Schirmer, B. & Hallowell, P. T., Jan 1 2018, In : Surgical endoscopy. 32, 1, p. 212-216 5 p.

Research output: Contribution to journalArticle

2 Scopus citations

Major adverse limb events and major adverse cardiac events after contemporary lower extremity bypass and infrainguinal endovascular intervention in patients with claudication

Fashandi, A. Z., Mehaffey, J. H., Hawkins, R. B., Kron, I. L., Upchurch, G. R. & Robinson, W. P., Dec 2018, In : Journal of vascular surgery. 68, 6, p. 1817-1823 7 p.

Research output: Contribution to journalArticle

5 Scopus citations

Minimally invasive mitral valve surgery is associated with excellent resource utilization, cost, and outcomes

Hawkins, R. B., Mehaffey, J. H., Kessel, S. M., Dahl, J. J., Kron, I. L., Kern, J. A., Yarboro, L. T. & Ailawadi, G., Aug 2018, In : Journal of Thoracic and Cardiovascular Surgery. 156, 2, p. 611-616.e3

Research output: Contribution to journalArticle

Open Access
3 Scopus citations

National Utilization and Outcomes of Redo Lower Extremity Bypass versus Endovascular Intervention after a Previous Failed Bypass

Mehaffey, J. H., Shannon, A., Hawkins, R. B., Fashandi, A., Tracci, M. C., Kron, I. L., Upchurch, G. R. & Robinson, W. P., Feb 2018, In : Annals of Vascular Surgery. 47, p. 18-23 6 p.

Research output: Contribution to journalArticle

4 Scopus citations

Need for Permanent Pacemaker After Surgical Aortic Valve Replacement Reduces Long-Term Survival

Mehaffey, J. H., Haywood, N. S., Hawkins, R. B., Kern, J. A., Teman, N. R., Kron, I. L., Yarboro, L. T. & Ailawadi, G., Aug 2018, In : Annals of Thoracic Surgery. 106, 2, p. 460-465 6 p.

Research output: Contribution to journalArticle

11 Scopus citations

Pannexin-1 channels on endothelial cells mediate vascular inflammation during lung ischemia-reperfusion injury

Sharma, A. K., Charles, E. J., Zhao, Y., Narahari, A. K., Baderdinni, P. K., Good, M. E., Lorenz, U. M., Kron, I. L., Bayliss, D. A., Ravichandran, K. S., Isakson, B. E. & Laubach, V. E., Aug 2018, In : American Journal of Physiology - Lung Cellular and Molecular Physiology. 315, 2, p. L301-L312

Research output: Contribution to journalArticle

13 Scopus citations

Preoperative anemia versus blood transfusion: Which is the culprit for worse outcomes in cardiac surgery?

Investigators for the Virginia Cardiac Services Quality Initiative, Jul 2018, In : Journal of Thoracic and Cardiovascular Surgery. 156, 1, p. 66-74.e2

Research output: Contribution to journalArticle

15 Scopus citations

Remote Ischemic Preconditioning: A Complex Question with an Even More Complex Answer

Schubert, S. A. & Kron, I. L., Mar 1 2018, In : Seminars in thoracic and cardiovascular surgery. 30, 1, p. 34-35 2 p.

Research output: Contribution to journalEditorial

Secondary surgical-site infection after coronary artery bypass grafting: A multi-institutional prospective cohort study

Cardiothoracic Surgical Trials Network (CTSN), Apr 2018, In : Journal of Thoracic and Cardiovascular Surgery. 155, 4, p. 1555-1562.e1

Research output: Contribution to journalArticle

7 Scopus citations

Stimulation of the Beta2 adrenergic receptor at reperfusion limits myocardial reperfusion injury via an interleukin-10-dependent anti-inflammatory pathway in the spleen

Tian, Y., Miao, B., Charles, E. J., Wu, D., Kron, I. L., French, B. A. & Yang, Z., Jan 1 2018, In : Circulation Journal. 82, 11, p. 2829-2836 8 p.

Research output: Contribution to journalArticle

Open Access
4 Scopus citations

Surgeon Scientists Are Disproportionately Affected by Declining NIH Funding Rates

Narahari, A. K., Mehaffey, J. H., Hawkins, R. B., Charles, E. J., Baderdinni, P. K., Chandrabhatla, A. S., Kocan, J. W., Jones, R. S., Upchurch, G. R., Kron, I. L., Kern, J. A. & Ailawadi, G., Apr 2018, In : Journal of the American College of Surgeons. 226, 4, p. 474-481 8 p.

Research output: Contribution to journalArticle

12 Scopus citations

The rest of the story: Long-term, patient-reported outcomes in cardiac surgery

Chancellor, W. Z. & Kron, I. L., Dec 2018, In : Journal of Thoracic and Cardiovascular Surgery. 156, 6, 1 p.

Research output: Contribution to journalEditorial

Open Access
1 Scopus citations

“See one, do one, teach one”: It is still possible in cardiothoracic surgical education

Beller, J. P. & Kron, I. L., Aug 2018, In : Journal of Thoracic and Cardiovascular Surgery. 156, 2, p. 716-717 2 p.

Research output: Contribution to journalEditorial

Open Access
2017

2016 update to The American Association for Thoracic Surgery (AATS) consensus guidelines: Ischemic mitral valve regurgitation

AATS Ischemic Mitral Regurgitation Consensus Guidelines Writing Committee, May 2017, In : Journal of Thoracic and Cardiovascular Surgery. 153, 5, p. e97-e114

Research output: Contribution to journalArticle

Open Access
12 Scopus citations

2016 update to The American Association for Thoracic Surgery consensus guidelines: Ischemic mitral valve regurgitation

The American Association For Thoracic Surgery Ischemic Mitral Regurgitation Consensus Guidelines Writing Committee, May 2017, In : Journal of Thoracic and Cardiovascular Surgery. 153, 5, p. 1076-1079 4 p.

Research output: Contribution to journalArticle

Open Access
18 Scopus citations

Access to Quaternary Care Surgery: Implications for Accountable Care Organizations

Mehaffey, J. H., Hawkins, R. B., Mullen, M. G., Meneveau, M. O., Schirmer, B., Kron, I. L., Jones, R. S. & Hallowell, P. T., Apr 1 2017, In : Journal of the American College of Surgeons. 224, 4, p. 525-529 5 p.

Research output: Contribution to journalArticle

10 Scopus citations

Airway pressure release ventilation during ex vivo lung perfusion attenuates injury

Mehaffey, J. H., Charles, E. J., Sharma, A. K., Money, D. T., Zhao, Y., Stoler, M. H., Lau, C. L., Tribble, C. G., Laubach, V. E., Roeser, M. E. & Kron, I. L., Jan 1 2017, In : Journal of Thoracic and Cardiovascular Surgery. 153, 1, p. 197-204 8 p.

Research output: Contribution to journalArticle

Open Access
15 Scopus citations

A New Intraoperative Protocol for Reducing Perioperative Transfusions in Cardiac Surgery

Mehaffey, J. H., Schubert, S. A., Gelvin, M. G., Charles, E. J., Hawkins, R. B., Johnston, L. E., Ailawadi, G., Kron, I. L. & Yarboro, L. T., Jul 2017, In : Annals of Thoracic Surgery. 104, 1, p. 176-181 6 p.

Research output: Contribution to journalArticle

Open Access
9 Scopus citations

Data, not dogma, for ischemic mitral regurgitation

Charles, E. J. & Kron, I. L., Jul 2017, In : Journal of Thoracic and Cardiovascular Surgery. 154, 1, p. 137-138 2 p.

Research output: Contribution to journalEditorial

Open Access
1 Scopus citations