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  • Irving L Kron
2020

Adenosine A2A receptor agonist (regadenoson) in Human Lung Transplantation

Lau, C. L., Beller, J. P., Boys, J. A., Zhao, Y., Phillips, J., Cosner, M., Conaway, M. R., Petroni, G., Charles, E. J., Mehaffey, J. H., Mannem, H. C., Kron, I. L., Krupnick, A. S. & Linden, J., Jun 2020, In : Journal of Heart and Lung Transplantation. 39, 6, p. 563-570 8 p.

Research output: Contribution to journalArticle

Commentary: Cervical aortic arch repair—an overarching success

Beller, J. P. & Kron, I. L., Jun 2020, In : Journal of Thoracic and Cardiovascular Surgery. 159, 6, p. 2214-2215 2 p.

Research output: Contribution to journalEditorial

Open Access

Commentary: Do not fear the ascending aorta

Byler, M. R. & Kron, I. L., May 2020, In : Journal of Thoracic and Cardiovascular Surgery. 159, 5, p. 1681-1682 2 p.

Research output: Contribution to journalEditorial

Open Access

Comprehensive National Institutes of Health funding analysis of academic cardiac surgeons

Narahari, A. K., Cook, I. O., Mehaffey, J. H., Chandrabhatla, A. S., Hawkins, R. B., Tyerman, Z., Charles, E. J., Tribble, C. G., Kron, I. L., Teman, N. R., Roeser, M. E. & Ailawadi, G., Jun 2020, In : Journal of Thoracic and Cardiovascular Surgery. 159, 6, p. 2326-2335.e3

Research output: Contribution to journalArticle

2 Scopus citations

Goal-directed resuscitation following cardiac surgery reduces acute kidney injury: A quality initiative pre–post analysis

The Virginia Interdisciplinary Cardiothoracic Outcomes Research Center, May 2020, In : Journal of Thoracic and Cardiovascular Surgery. 159, 5, p. 1868-1877.e1

Research output: Contribution to journalArticle

2 Scopus citations

Impact of Complications After Cardiac Operation on One-Year Patient-Reported Outcomes

Mehaffey, J. H., Hawkins, R. B., Charles, E. J., Kron, I. L., Ailawadi, G., Kern, J. A., Roeser, M. E., Kozower, B. & Teman, N. R., Jan 2020, In : Annals of Thoracic Surgery. 109, 1, p. 43-48 6 p.

Research output: Contribution to journalArticle

Mortality After Repeat Revascularization Following PCI or CABG for Left Main Disease: The EXCEL Trial

Giustino, G., Serruys, P. W., Sabik, J. F., Mehran, R., Maehara, A., Puskas, J. D., Simonton, C. A., Lembo, N. J., Kandzari, D. E., Morice, M. C., Taggart, D. P., Gershlick, A. H., Ragosta, M., Kron, I. L., Liu, Y., Zhang, Z., McAndrew, T., Dressler, O., Généreux, P., Ben-Yehuda, O. & 3 others, Pocock, S. J., Kappetein, A. P. & Stone, G. W., Feb 10 2020, In : JACC: Cardiovascular Interventions. 13, 3, p. 375-387 13 p.

Research output: Contribution to journalArticle

1 Scopus citations

Persistent cognitive deficits and neuroinflammation in a rat model of cardiopulmonary bypass

Wang, Y., Tache-Leon, C., Machizawa, M. G., Lisle, T., Williams, C., Clarke, R. H., Anzivino, M. J., Kron, I. & Lee, K. S., Jan 1 2020, (Accepted/In press) In : Journal of Thoracic and Cardiovascular Surgery.

Research output: Contribution to journalArticle

1 Scopus citations

Reduced-flow ex vivo lung perfusion to rehabilitate lungs donated after circulatory death

Beller, J. P., Byler, M. R., Money, D. T., Chancellor, W. Z., Zhang, A., Zhao, Y., Stoler, M. H., Narahari, A. K., Shannon, A., Mehaffey, J. H., Tribble, C. G., Laubach, V. E., Kron, I. L. & Roeser, M. E., Jan 2020, In : Journal of Heart and Lung Transplantation. 39, 1, p. 74-82 9 p.

Research output: Contribution to journalArticle

Risk Aversion in Cardiac Surgery: 15-Year Trends in a Statewide Analysis

Investigators for the Virginia Cardiac Services Quality Initiative, May 2020, In : Annals of Thoracic Surgery. 109, 5, p. 1401-1407 7 p.

Research output: Contribution to journalArticle

1 Scopus citations

Risk for non-home discharge following surgery for ischemic mitral valve disease

Cardiothoracic Surgical Trials Network (CTSN) Working Group, Jan 1 2020, (Accepted/In press) In : Journal of Thoracic and Cardiovascular Surgery.

Research output: Contribution to journalArticle

SPECT imaging of lung ischemia-reperfusion injury using [99mTc]cFLFLF for molecular targeting of formyl peptide receptor 1

Charles, E. J., Chordia, M. D., Zhao, Y., Zhang, Y., Mehaffey, J. H., Glover, D. K., Dimastromatteo, J., Chancellor, W. Z., Sharma, A. K., Kron, I. L., Pan, D. & Laubach, V. E., Feb 1 2020, In : American journal of physiology. Lung cellular and molecular physiology. 318, 2, p. L304-L313

Research output: Contribution to journalArticle

Open Access
1 Scopus citations
2019

Adenosine 2A Receptor Activation Attenuates Ischemia Reperfusion Injury During Extracorporeal Cardiopulmonary Resuscitation

Mehaffey, J. H., Money, D., Charles, E. J., Schubert, S., Piñeros, A. F., Wu, D., Bontha, S. V., Hawkins, R., Teman, N. R., Laubach, V. E., Mas, V. R., Tribble, C. G., Maluf, D. G., Sharma, A. K., Yang, Z., Kron, I. L. & Roeser, M. E., Jun 1 2019, In : Annals of surgery. 269, 6, p. 1176-1183 8 p.

Research output: Contribution to journalArticle

3 Scopus citations

A focused approach: Specialization in coronary revascularization

Chancellor, W. Z. & Kron, I. L., Mar 2019, In : Journal of Thoracic and Cardiovascular Surgery. 157, 3, p. 948-949 2 p.

Research output: Contribution to journalEditorial

Open Access

Biatrial maze procedure versus pulmonary vein isolation for atrial fibrillation during mitral valve surgery: New analytical approaches and end points

Cardiothoracic Surgical Trials Network Investigators, Jan 2019, In : Journal of Thoracic and Cardiovascular Surgery. 157, 1, p. 234-243.e9

Research output: Contribution to journalArticle

Open Access
7 Scopus citations

Can lung transplant surgeons still be scientists? High productivity despite competitive funding

Narahari, A. K., Charles, E. J., Hunter Mehaffey, J., Hawkins, R. B., Sharma, A. K., Laubach, V. E., Tribble, C. G. & Kron, I. L., Jan 2019, In : Heart Surgery Forum. 22, 1, p. E1-E7

Research output: Contribution to journalArticle

Open Access
2 Scopus citations

Cost-effectiveness of coronary artery bypass grafting plus mitral valve repair versus coronary artery bypass grafting alone for moderate ischemic mitral regurgitation

Cardiothoracic Surgical Trials Network Investigators, Jan 1 2019, (Accepted/In press) In : Journal of Thoracic and Cardiovascular Surgery.

Research output: Contribution to journalArticle

2 Scopus citations

Determining which prosthetic to use during aortic valve replacement in patients aged younger than 70 years: A systematic review of the literature

Borger, P., Charles, E. J., Smith, E. D., Hunter Mehaffey, J., Hawkins, R. B., Kron, I. L., Ailawadi, G. & Teman, N., Jan 1 2019, In : Heart Surgery Forum. 22, 2, p. E70-E81

Research output: Contribution to journalArticle

1 Scopus citations

Development and Validation of Procedure-Specific Risk Score for Predicting Postoperative Pulmonary Complication: A NSQIP Analysis

Foster, C. A., Charles, E. J., Turrentine, F. E., Sohn, M. W., Kron, I. L. & Jones, R. S., Oct 2019, In : Journal of the American College of Surgeons. 229, 4, p. 355-365.e3

Research output: Contribution to journalArticle

1 Scopus citations

One-Year Outcomes after MitraClip for Functional Mitral Regurgitation

Ailawadi, G., Lim, D. S., Mack, M. J., Trento, A., Kar, S., Grayburn, P. A., Glower, D. D., Wang, A., Foster, E., Qasim, A., Weissman, N. J., Ellis, J., Crosson, L., Fan, F., Kron, I. L., Pearson, P. J. & Feldman, T., Jan 2 2019, In : Circulation. 139, 1, p. 37-47 11 p.

Research output: Contribution to journalArticle

Open Access
16 Scopus citations

Outcomes of left main revascularization in patients with acute coronary syndromes and stable ischemic heart disease: Analysis from the EXCEL trial

Doucet, S., Jolicœur, E. M., Serruys, P. W., Ragosta, M., Kron, I. L., Scholtz, W., Börgermann, J., Zhang, Y., McAndrew, T., Sabik, J. F., Kappetein, A. P. & Stone, G. W., Aug 2019, In : American Heart Journal. 214, p. 9-17 9 p.

Research output: Contribution to journalArticle

2 Scopus citations

Pacemaker Implantation After Mitral Valve Surgery With Atrial Fibrillation Ablation

CTSN Investigators, May 21 2019, In : Journal of the American College of Cardiology. 73, 19, p. 2427-2435 9 p.

Research output: Contribution to journalArticle

2 Scopus citations

Preoperative β-blocker use correlates with worse outcomes in patients undergoing aortic valve replacement

Schubert, S. A., Hawkins, R. B., Mehaffey, J. H., Fonner, C. E., Rich, J. B., Speir, A. M., Quader, M., Kron, I. L., Yarboro, L. T. & Ailawadi, G., Dec 2019, In : Journal of Thoracic and Cardiovascular Surgery. 158, 6, p. 1589-1597.e3

Research output: Contribution to journalArticle

10 Scopus citations

Pulsed ultrasound attenuates the hyperglycemic exacerbation of myocardial ischemia–reperfusion injury

Charles, E. J., Tian, Y., Zhang, A., Wu, D., Mehaffey, J. H., Gigliotti, J. C., Klibanov, A. L., Kron, I. L. & Yang, Z., Jan 1 2019, (Accepted/In press) In : Journal of Thoracic and Cardiovascular Surgery.

Research output: Contribution to journalArticle

2 Scopus citations

Socioeconomic Distressed Communities Index Predicts Risk-Adjusted Mortality After Cardiac Surgery

Investigators for the Virginia Cardiac Services Quality Initiative, Jun 2019, In : Annals of Thoracic Surgery. 107, 6, p. 1706-1712 7 p.

Research output: Contribution to journalArticle

3 Scopus citations

The myocardial infarct-exacerbating effect of cell-free DNA is mediated by the high-mobility group box 1–receptor for advanced glycation end products–Toll-like receptor 9 pathway

Tian, Y., Charles, E. J., Yan, Z., Wu, D., French, B. A., Kron, I. L. & Yang, Z., Jun 2019, In : Journal of Thoracic and Cardiovascular Surgery. 157, 6, p. 2256-2269.e3

Research output: Contribution to journalArticle

Open Access
6 Scopus citations

Travel distance and regional access to cardiac valve surgery

Hawkins, R. B., Byler, M., Fonner, C., Kron, I. L., Yarboro, L. T., Speir, A. M., Quader, M. A., Ailawadi, G. & Mehaffey, J. H., Oct 1 2019, In : Journal of Cardiac Surgery. 34, 10, p. 1044-1048 5 p.

Research output: Contribution to journalArticle

2017

2016 update to The American Association for Thoracic Surgery (AATS) consensus guidelines: Ischemic mitral valve regurgitation

AATS Ischemic Mitral Regurgitation Consensus Guidelines Writing Committee, May 2017, In : Journal of Thoracic and Cardiovascular Surgery. 153, 5, p. e97-e114

Research output: Contribution to journalArticle

Open Access
12 Scopus citations

2016 update to The American Association for Thoracic Surgery consensus guidelines: Ischemic mitral valve regurgitation

The American Association For Thoracic Surgery Ischemic Mitral Regurgitation Consensus Guidelines Writing Committee, May 2017, In : Journal of Thoracic and Cardiovascular Surgery. 153, 5, p. 1076-1079 4 p.

Research output: Contribution to journalArticle

Open Access
18 Scopus citations

Access to Quaternary Care Surgery: Implications for Accountable Care Organizations

Mehaffey, J. H., Hawkins, R. B., Mullen, M. G., Meneveau, M. O., Schirmer, B., Kron, I. L., Jones, R. S. & Hallowell, P. T., Apr 1 2017, In : Journal of the American College of Surgeons. 224, 4, p. 525-529 5 p.

Research output: Contribution to journalArticle

10 Scopus citations

Airway pressure release ventilation during ex vivo lung perfusion attenuates injury

Mehaffey, J. H., Charles, E. J., Sharma, A. K., Money, D. T., Zhao, Y., Stoler, M. H., Lau, C. L., Tribble, C. G., Laubach, V. E., Roeser, M. E. & Kron, I. L., Jan 1 2017, In : Journal of Thoracic and Cardiovascular Surgery. 153, 1, p. 197-204 8 p.

Research output: Contribution to journalArticle

Open Access
15 Scopus citations

A New Intraoperative Protocol for Reducing Perioperative Transfusions in Cardiac Surgery

Mehaffey, J. H., Schubert, S. A., Gelvin, M. G., Charles, E. J., Hawkins, R. B., Johnston, L. E., Ailawadi, G., Kron, I. L. & Yarboro, L. T., Jul 2017, In : Annals of Thoracic Surgery. 104, 1, p. 176-181 6 p.

Research output: Contribution to journalArticle

Open Access
9 Scopus citations

Data, not dogma, for ischemic mitral regurgitation

Charles, E. J. & Kron, I. L., Jul 2017, In : Journal of Thoracic and Cardiovascular Surgery. 154, 1, p. 137-138 2 p.

Research output: Contribution to journalEditorial

Open Access
1 Scopus citations

Decubitus ulcers in patients undergoing vascular operations do not influence mortality but affect resource utilization

Mehaffey, J. H., Politano, A. D., Bhamidipati, C. M., Tracci, M. C., Cherry, K. J., Kern, J. A., Kron, I. L. & Upchurch, G. R., Jun 2017, In : Surgery (United States). 161, 6, p. 1720-1727 8 p.

Research output: Contribution to journalArticle

2 Scopus citations

Ex Vivo Lung Perfusion Rehabilitates Sepsis-Induced Lung Injury

Mehaffey, J. H., Charles, E. J., Sharma, A. K., Salmon, M., Money, D., Schubert, S., Stoler, M. H., Tribble, C. G., Laubach, V. E., Roeser, M. E. & Kron, I. L., Jun 2017, In : Annals of Thoracic Surgery. 103, 6, p. 1723-1729 7 p.

Research output: Contribution to journalArticle

Open Access
8 Scopus citations

Impact of Medicaid Expansion on Cardiac Surgery Volume and Outcomes

Investigators for the Virginia Cardiac Services Quality Initiative and the Michigan Society of Thoracic and Cardiovascular Surgeons Quality Collaborative, Oct 2017, In : Annals of Thoracic Surgery. 104, 4, p. 1251-1258 8 p.

Research output: Contribution to journalArticle

19 Scopus citations

Improved outcomes and value in staged hybrid extent II thoracoabdominal aortic aneurysm repair

Hawkins, R. B., Mehaffey, J. H., Narahari, A. K., Jain, A., Ghanta, R. K., Kron, I. L., Kern, J. A. & Upchurch, G. R., Nov 2017, In : Journal of vascular surgery. 66, 5, p. 1357-1363 7 p.

Research output: Contribution to journalArticle

Open Access
8 Scopus citations

Lower extremity bypass for critical limb ischemia decreases major adverse limb events with equivalent cardiac risk compared with endovascular intervention

Mehaffey, J. H., Hawkins, R. B., Fashandi, A., Cherry, K. J., Kern, J. A., Kron, I. L., Upchurch, G. R. & Robinson, W. P., Oct 2017, In : Journal of vascular surgery. 66, 4, p. 1109-1116.e1

Research output: Contribution to journalArticle

Open Access
15 Scopus citations

Lungs donated after circulatory death and prolonged warm ischemia are transplanted successfully after enhanced ex vivo lung perfusion using adenosine A2B receptor antagonism

Charles, E. J., Mehaffey, J. H., Sharma, A. K., Zhao, Y., Stoler, M. H., Isbell, J. M., Lau, C. L., Tribble, C. G., Laubach, V. E. & Kron, I. L., Nov 2017, In : Journal of Thoracic and Cardiovascular Surgery. 154, 5, p. 1811-1820 10 p.

Research output: Contribution to journalArticle

Open Access
16 Scopus citations

Management of Ebstein's anomaly

Kron, I. L. & Roeser, M. E., May 1 2017, In : Annals of Cardiothoracic Surgery. 6, 3, p. 266-269 4 p.

Research output: Contribution to journalArticle

Open Access
2 Scopus citations

Mesenchymal stromal cell-derived extracellular vesicles attenuate lung ischemia-reperfusion injury and enhance reconditioning of donor lungs after circulatory death

Stone, M. L., Zhao, Y., Robert Smith, J., Weiss, M. L., Kron, I. L., Laubach, V. E. & Sharma, A. K., Dec 21 2017, In : Respiratory Research. 18, 1, 212.

Research output: Contribution to journalArticle

Open Access
25 Scopus citations

Methylene Blue for Vasoplegic Syndrome After Cardiac Operation: Early Administration Improves Survival

Mehaffey, J. H., Johnston, L. E., Hawkins, R. B., Charles, E. J., Yarboro, L., Kern, J. A., Ailawadi, G., Kron, I. L. & Ghanta, R. K., Jul 2017, In : Annals of Thoracic Surgery. 104, 1, p. 36-41 6 p.

Research output: Contribution to journalArticle

Open Access
24 Scopus citations

Mitral Valve Repair: The French Correction Versus the American Correction

Schubert, S. A., Mehaffey, J. H., Charles, E. J. & Kron, I. L., Aug 2017, In : Surgical Clinics of North America. 97, 4, p. 867-888 22 p.

Research output: Contribution to journalReview article

9 Scopus citations

Modifiable Factors Leading to Increased Length of Stay after Carotid Endarterectomy

Mehaffey, J. H., LaPar, D. J., Tracci, M. C., Cherry, K. J., Kern, J. A., Kron, I. & Upchurch, G. R., Feb 1 2017, In : Annals of Vascular Surgery. 39, p. 195-203 9 p.

Research output: Contribution to journalArticle

9 Scopus citations

Obesity increases risk-adjusted morbidity, mortality, and cost following cardiac surgery

Ghanta, R. K., LaPar, D. J., Zhang, Q., Devarkonda, V., Isbell, J. M., Yarboro, L. T., Kern, J. A., Kron, I. L., Speir, A. M., Fonner, C. E. & Ailawadi, G., Jan 1 2017, In : Journal of the American Heart Association. 6, 3, e003831.

Research output: Contribution to journalArticle

Open Access
28 Scopus citations

Outcomes of Trainees Performing Coronary Artery Bypass Grafting: Does Resident Experience Matter?

Yount, K. W., Yarboro, L. T., Narahari, A. K., Ghanta, R. K., Tribble, C. G., Kron, I. L., Kern, J. A. & Ailawadi, G., Mar 1 2017, In : Annals of Thoracic Surgery. 103, 3, p. 975-981 7 p.

Research output: Contribution to journalArticle

Open Access
8 Scopus citations

Postoperative Hypoglycemia Is Associated With Worse Outcomes After Cardiac Operations

Johnston, L. E., Kirby, J. L., Downs, E. A., LaPar, D. J., Ghanta, R. K., Ailawadi, G., Kozower, B. D., Kron, I. L., McCall, A. L. & Isbell, J. M., Feb 1 2017, In : Annals of Thoracic Surgery. 103, 2, p. 526-532 7 p.

Research output: Contribution to journalArticle

Open Access
5 Scopus citations

Predicting recurrent mitral regurgitation after mitral valve repair: A difficult endeavor and a necessity

Bouchard, D., Perrault, L. P., Kron, I. L. & Hung, J. W., Jan 1 2017, In : Journal of Thoracic and Cardiovascular Surgery. 153, 1, p. 145-146 2 p.

Research output: Contribution to journalLetter

Open Access

Pre-implant left ventricular apex position predicts risk of HeartMate II pump thrombosis

Yarboro, L. T., Mehaffey, J. H., Hawkins, R. B., Kron, I. L., Ailawadi, G., Kern, J. A. & Ghanta, R. K., Dec 2017, In : Journal of Cardiac Surgery. 32, 12, p. 837-842 6 p.

Research output: Contribution to journalArticle

2 Scopus citations

Repairing the mitral subvalvular apparatus: The new frontier

Charles, E. J. & Kron, I. L., Feb 1 2017, In : Journal of Thoracic and Cardiovascular Surgery. 153, 2, p. 284-285 2 p.

Research output: Contribution to journalEditorial

Open Access
3 Scopus citations