A case-control study of risk factors in men with chronic pelvic pain syndrome

Michel A. Pontari, Mary McNaughton-Collins, Michael P. O'Leary, Elizabeth Calhoun, Thomas Jang, John W. Kusek, J. Richard Landis, Jill Knauss, Mark S. Litwin

Research output: Contribution to journalArticle

70 Citations (Scopus)

Abstract

OBJECTIVE: To compare the demographic, behavioural, clinical and medical history characteristics of men with chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS) and asymptomatic controls, to identify characteristics that might be associated with this syndrome. PATIENTS AND METHODS: Self-administered epidemiological questionnaires were completed by 463 men with CP/CPPS and 121 asymptomatic age-matched controls. We compared the prevalence of possible risk factors between men with CP/CPPS and controls, using generalized Mantel-Haenszel tests, and developed multivariate predictive models using logistic regression methods, adjusting for clustering by clinical centre within both methods. RESULTS: Compared to controls, men with CP/CPPS reported a significantly greater lifetime prevalence of nonspecific urethritis (12% vs 4%, P = 0.008), cardiovascular disease (11% vs 2%, P = 0.004), neurological disease (41% vs 14%, P < 0.001), psychiatric conditions (29% vs 11%, P < 0.001), and haematopoietic, lymphatic or infectious disease (41% vs 20%, P < 0.001). CONCLUSION: A wide range of self-reported medical conditions was associated with CP/CPPS. Further studies are necessary to determine whether they play a role in the pathogenesis of CP/CPPS.

Original languageEnglish (US)
Pages (from-to)559-565
Number of pages7
JournalBJU International
Volume96
Issue number4
DOIs
StatePublished - Sep 2005
Externally publishedYes

Fingerprint

Prostatitis
Pelvic Pain
Chronic Pain
Case-Control Studies
Urethritis
Lymphatic Diseases
Communicable Diseases
Cluster Analysis
Psychiatry
Cardiovascular Diseases
Logistic Models
Demography

Keywords

  • Chronic prostatitis
  • Hypertension
  • Pelvic pain
  • Urethritis

ASJC Scopus subject areas

  • Urology

Cite this

Pontari, M. A., McNaughton-Collins, M., O'Leary, M. P., Calhoun, E., Jang, T., Kusek, J. W., ... Litwin, M. S. (2005). A case-control study of risk factors in men with chronic pelvic pain syndrome. BJU International, 96(4), 559-565. https://doi.org/10.1111/j.1464-410X.2005.05684.x

A case-control study of risk factors in men with chronic pelvic pain syndrome. / Pontari, Michel A.; McNaughton-Collins, Mary; O'Leary, Michael P.; Calhoun, Elizabeth; Jang, Thomas; Kusek, John W.; Landis, J. Richard; Knauss, Jill; Litwin, Mark S.

In: BJU International, Vol. 96, No. 4, 09.2005, p. 559-565.

Research output: Contribution to journalArticle

Pontari, MA, McNaughton-Collins, M, O'Leary, MP, Calhoun, E, Jang, T, Kusek, JW, Landis, JR, Knauss, J & Litwin, MS 2005, 'A case-control study of risk factors in men with chronic pelvic pain syndrome', BJU International, vol. 96, no. 4, pp. 559-565. https://doi.org/10.1111/j.1464-410X.2005.05684.x
Pontari, Michel A. ; McNaughton-Collins, Mary ; O'Leary, Michael P. ; Calhoun, Elizabeth ; Jang, Thomas ; Kusek, John W. ; Landis, J. Richard ; Knauss, Jill ; Litwin, Mark S. / A case-control study of risk factors in men with chronic pelvic pain syndrome. In: BJU International. 2005 ; Vol. 96, No. 4. pp. 559-565.
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