A clinical and histopathological study of François-Neetens speckled corneal dystrophy

Don H. Nicholson, W. Richard Green, Harold E Cross, Kenneth R. Kenyon, Darcy Massof

Research output: Contribution to journalArticle

26 Citations (Scopus)

Abstract

A 57-year-old black man had François-Neetens speckled dystrophy of the cornea and orbital phycomycosis. Examination of family members confirmed an autosomal-dominant pattern of inheritance. Light and electron microscopic study of the cornea of a blind eye disclosed that the corneal opacities were represented by swollen, vacuolated keratocytes filled with histochemically demonstrable acid mucopolysaccharide and complex lipids. Thus, this dystrophy may represent a dominantly inherited metabolic disorder confined to the cornea.

Original languageEnglish (US)
Pages (from-to)554-560
Number of pages7
JournalAmerican Journal of Ophthalmology
Volume83
Issue number4
StatePublished - 1977

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Cornea
Zygomycosis
Corneal Opacity
Inheritance Patterns
Glycosaminoglycans
Electrons
Lipids
Light
Acids
Clinical Studies

ASJC Scopus subject areas

  • Ophthalmology

Cite this

A clinical and histopathological study of François-Neetens speckled corneal dystrophy. / Nicholson, Don H.; Green, W. Richard; Cross, Harold E; Kenyon, Kenneth R.; Massof, Darcy.

In: American Journal of Ophthalmology, Vol. 83, No. 4, 1977, p. 554-560.

Research output: Contribution to journalArticle

Nicholson, DH, Green, WR, Cross, HE, Kenyon, KR & Massof, D 1977, 'A clinical and histopathological study of François-Neetens speckled corneal dystrophy', American Journal of Ophthalmology, vol. 83, no. 4, pp. 554-560.
Nicholson, Don H. ; Green, W. Richard ; Cross, Harold E ; Kenyon, Kenneth R. ; Massof, Darcy. / A clinical and histopathological study of François-Neetens speckled corneal dystrophy. In: American Journal of Ophthalmology. 1977 ; Vol. 83, No. 4. pp. 554-560.
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