A comparison of surgical outcomes and quality of life surveys in right lobe vs. left lateral segment liver donors

Abhinav Humar, Eric Carolan, Hassan Ibrahim, Kirsten Horn, Elizabeth Larson, Brooke Glessing, Raja Kandaswamy, Rainer W G Gruessner, John Lake, William D. Payne

Research output: Contribution to journalArticle

26 Scopus citations

Abstract

Concern remains regarding the possibly higher risk to living liver donors of the right lobe (RL), as compared with the left lateral segment (LLS). We studied outcomes and responses to quality of life (QOL) surveys in the two groups. From 1997 to 2004, we performed 49 living donor liver transplants (LDLTs): 33 RL and 16 LLS. Notable differences included a higher proportion of female and unrelated donors in the RL group. A significantly larger liver mass was resected in RL (vs. LLS) donors: 720 (vs. 310) g, p = 0.01; RL donors also had greater blood loss (398 vs. 240 m L, p = 0.04) and operative times (7.2 vs. 5.7 h, p = 0.05). However, those findings did not translate into significant differences in donor morbidity. The complication rate was 12.5% in LLS donors and 9.1% in RL donors (p = ns). Per a QOL survey at 6 months postdonation, no significant differences were noted in SF-12 scores for the two groups. Recovery times were somewhat longer for RL donors. Mean time off work was 61.0 days for RL donors and 32.4 days for LLS donors (p = 0.004). RL donation is associated with greater operative stress for donors, but not necessarily with a more complicated recovery or differences in QOL.

Original languageEnglish (US)
Pages (from-to)805-809
Number of pages5
JournalAmerican Journal of Transplantation
Volume5
Issue number4 I
DOIs
Publication statusPublished - Apr 2005
Externally publishedYes

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Keywords

  • Donor outcomes
  • Living donor liver
  • Quality of life

ASJC Scopus subject areas

  • Immunology

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