A fiber-optic confocal microendoscope as a daughter scope for clinical endoscopy

Andrew R Rouse, Angelique Kano, Shona M. Kroto, Arthur F Gmitro

Research output: Chapter in Book/Report/Conference proceedingConference contribution

3 Citations (Scopus)

Abstract

A fluorescence confocal microendoscope has been developed to provide high resolution, in-vivo imaging of cellular pathology. The microendoscope employs a fiber-optic imaging bundle, a miniature objective, and a miniature focusing mechanism to allow imaging in remote locations of the body. The system uses a 2mm diameter flexible catheter that is capped by a rigid opto-mechanical system measuring 3mm in diameter and 12 mm in length. The small size of the confocal microendoscope was chosen to that it may be routed through the therapeutic channel of a clinical endoscope, adding microscopic functionality to conventional endoscopy procedures. The confocal nature of the microendoscope provides optical sectioning with 2 micron lateral resolution and 25 micron axial resolution. The pneumatic focusing mechanism located in the distal opto-mechanical assembly allows for imaging to a maximum depth of 200 micron in the tissue. Preliminary results are presented.

Original languageEnglish (US)
Title of host publicationProceedings of SPIE - The International Society for Optical Engineering
EditorsI. Gannot
Pages70-78
Number of pages9
Volume4957
DOIs
StatePublished - 2003
EventPROGRESS IN BIOMEDICAL OPTICS AND IMAGING: Optical Fibers and Sensors for Medical Applications III - San Jose, CA, United States
Duration: Jan 25 2003Jan 28 2003

Other

OtherPROGRESS IN BIOMEDICAL OPTICS AND IMAGING: Optical Fibers and Sensors for Medical Applications III
CountryUnited States
CitySan Jose, CA
Period1/25/031/28/03

Fingerprint

Endoscopy
Fiber optics
fiber optics
Imaging techniques
endoscopes
pneumatics
Optical resolving power
pathology
bundles
assembly
fluorescence
Catheters
high resolution
Pathology
Pneumatics
Fluorescence
Tissue

ASJC Scopus subject areas

  • Electrical and Electronic Engineering
  • Condensed Matter Physics

Cite this

Rouse, A. R., Kano, A., Kroto, S. M., & Gmitro, A. F. (2003). A fiber-optic confocal microendoscope as a daughter scope for clinical endoscopy. In I. Gannot (Ed.), Proceedings of SPIE - The International Society for Optical Engineering (Vol. 4957, pp. 70-78) https://doi.org/10.1117/12.478058

A fiber-optic confocal microendoscope as a daughter scope for clinical endoscopy. / Rouse, Andrew R; Kano, Angelique; Kroto, Shona M.; Gmitro, Arthur F.

Proceedings of SPIE - The International Society for Optical Engineering. ed. / I. Gannot. Vol. 4957 2003. p. 70-78.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Rouse, AR, Kano, A, Kroto, SM & Gmitro, AF 2003, A fiber-optic confocal microendoscope as a daughter scope for clinical endoscopy. in I Gannot (ed.), Proceedings of SPIE - The International Society for Optical Engineering. vol. 4957, pp. 70-78, PROGRESS IN BIOMEDICAL OPTICS AND IMAGING: Optical Fibers and Sensors for Medical Applications III, San Jose, CA, United States, 1/25/03. https://doi.org/10.1117/12.478058
Rouse AR, Kano A, Kroto SM, Gmitro AF. A fiber-optic confocal microendoscope as a daughter scope for clinical endoscopy. In Gannot I, editor, Proceedings of SPIE - The International Society for Optical Engineering. Vol. 4957. 2003. p. 70-78 https://doi.org/10.1117/12.478058
Rouse, Andrew R ; Kano, Angelique ; Kroto, Shona M. ; Gmitro, Arthur F. / A fiber-optic confocal microendoscope as a daughter scope for clinical endoscopy. Proceedings of SPIE - The International Society for Optical Engineering. editor / I. Gannot. Vol. 4957 2003. pp. 70-78
@inproceedings{a79208b4b91d4986bd6a28798f22577f,
title = "A fiber-optic confocal microendoscope as a daughter scope for clinical endoscopy",
abstract = "A fluorescence confocal microendoscope has been developed to provide high resolution, in-vivo imaging of cellular pathology. The microendoscope employs a fiber-optic imaging bundle, a miniature objective, and a miniature focusing mechanism to allow imaging in remote locations of the body. The system uses a 2mm diameter flexible catheter that is capped by a rigid opto-mechanical system measuring 3mm in diameter and 12 mm in length. The small size of the confocal microendoscope was chosen to that it may be routed through the therapeutic channel of a clinical endoscope, adding microscopic functionality to conventional endoscopy procedures. The confocal nature of the microendoscope provides optical sectioning with 2 micron lateral resolution and 25 micron axial resolution. The pneumatic focusing mechanism located in the distal opto-mechanical assembly allows for imaging to a maximum depth of 200 micron in the tissue. Preliminary results are presented.",
author = "Rouse, {Andrew R} and Angelique Kano and Kroto, {Shona M.} and Gmitro, {Arthur F}",
year = "2003",
doi = "10.1117/12.478058",
language = "English (US)",
volume = "4957",
pages = "70--78",
editor = "I. Gannot",
booktitle = "Proceedings of SPIE - The International Society for Optical Engineering",

}

TY - GEN

T1 - A fiber-optic confocal microendoscope as a daughter scope for clinical endoscopy

AU - Rouse, Andrew R

AU - Kano, Angelique

AU - Kroto, Shona M.

AU - Gmitro, Arthur F

PY - 2003

Y1 - 2003

N2 - A fluorescence confocal microendoscope has been developed to provide high resolution, in-vivo imaging of cellular pathology. The microendoscope employs a fiber-optic imaging bundle, a miniature objective, and a miniature focusing mechanism to allow imaging in remote locations of the body. The system uses a 2mm diameter flexible catheter that is capped by a rigid opto-mechanical system measuring 3mm in diameter and 12 mm in length. The small size of the confocal microendoscope was chosen to that it may be routed through the therapeutic channel of a clinical endoscope, adding microscopic functionality to conventional endoscopy procedures. The confocal nature of the microendoscope provides optical sectioning with 2 micron lateral resolution and 25 micron axial resolution. The pneumatic focusing mechanism located in the distal opto-mechanical assembly allows for imaging to a maximum depth of 200 micron in the tissue. Preliminary results are presented.

AB - A fluorescence confocal microendoscope has been developed to provide high resolution, in-vivo imaging of cellular pathology. The microendoscope employs a fiber-optic imaging bundle, a miniature objective, and a miniature focusing mechanism to allow imaging in remote locations of the body. The system uses a 2mm diameter flexible catheter that is capped by a rigid opto-mechanical system measuring 3mm in diameter and 12 mm in length. The small size of the confocal microendoscope was chosen to that it may be routed through the therapeutic channel of a clinical endoscope, adding microscopic functionality to conventional endoscopy procedures. The confocal nature of the microendoscope provides optical sectioning with 2 micron lateral resolution and 25 micron axial resolution. The pneumatic focusing mechanism located in the distal opto-mechanical assembly allows for imaging to a maximum depth of 200 micron in the tissue. Preliminary results are presented.

UR - http://www.scopus.com/inward/record.url?scp=0345413416&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0345413416&partnerID=8YFLogxK

U2 - 10.1117/12.478058

DO - 10.1117/12.478058

M3 - Conference contribution

AN - SCOPUS:0345413416

VL - 4957

SP - 70

EP - 78

BT - Proceedings of SPIE - The International Society for Optical Engineering

A2 - Gannot, I.

ER -