A high-resolution CdTe imaging detector with multi-pinhole optics for in-vivo molecular imaging

Shin'ichiro Takeda, Miho Katsuragawa, Tadashi Orita, Fumiki Moriyama, Yasuo Arai, Hirotaka Sugawara, Sayuri Oshita, Goro Yabu, Shin Watanabe, Tadayuki Takahashi, Lars R Furenlid

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

High-resolution CdTe semiconductor detectors with both fine position resolution and high energy resolution hold great promise to improve measurement in various hard X-ray and gamma-ray imaging experiments. In the field of in-vivo molecular imaging, where the molecules labeled with radioisotopes are injected into a small animal and their distribution in a body is detected by gamma-ray imaging detectors externally, a large detection area is also required to obtain a number of projections from multiple pinholes. We have developed a prototype imaging system consisting of a 32 mm-wide CdTe double-sided strip detector equipped with multi-pinhole optics. We describe its imaging capability, as studied through experiments with radioisotopes for medical use (125I and 111In) and a 3D phantom.

Fingerprint

Molecular imaging
Optical resolving power
pinholes
Optics
optics
Detectors
Imaging techniques
Radioisotopes
Gamma rays
high resolution
detectors
gamma rays
Semiconductor detectors
Imaging systems
animals
strip
Animals
projection
Experiments
prototypes

Keywords

  • CdTe
  • Gamma-ray
  • In-vivo
  • Molecular imaging
  • Semiconductor detectors

ASJC Scopus subject areas

  • Nuclear and High Energy Physics
  • Instrumentation

Cite this

A high-resolution CdTe imaging detector with multi-pinhole optics for in-vivo molecular imaging. / Takeda, Shin'ichiro; Katsuragawa, Miho; Orita, Tadashi; Moriyama, Fumiki; Arai, Yasuo; Sugawara, Hirotaka; Oshita, Sayuri; Yabu, Goro; Watanabe, Shin; Takahashi, Tadayuki; Furenlid, Lars R.

In: Nuclear Instruments and Methods in Physics Research, Section A: Accelerators, Spectrometers, Detectors and Associated Equipment, 01.01.2017.

Research output: Contribution to journalArticle

Takeda, Shin'ichiro ; Katsuragawa, Miho ; Orita, Tadashi ; Moriyama, Fumiki ; Arai, Yasuo ; Sugawara, Hirotaka ; Oshita, Sayuri ; Yabu, Goro ; Watanabe, Shin ; Takahashi, Tadayuki ; Furenlid, Lars R. / A high-resolution CdTe imaging detector with multi-pinhole optics for in-vivo molecular imaging. In: Nuclear Instruments and Methods in Physics Research, Section A: Accelerators, Spectrometers, Detectors and Associated Equipment. 2017.
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AU - Katsuragawa, Miho

AU - Orita, Tadashi

AU - Moriyama, Fumiki

AU - Arai, Yasuo

AU - Sugawara, Hirotaka

AU - Oshita, Sayuri

AU - Yabu, Goro

AU - Watanabe, Shin

AU - Takahashi, Tadayuki

AU - Furenlid, Lars R

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