A model for optimizing normal tissue complication probability in the spinal cord using a generalized incomplete repair scheme

D. Levin-Plotnik, Russell J Hamilton, A. Niemierko, S. Akselrod

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

To determine the dose fraction sizes and interfraction intervals (IFIs) that minimize the Normal Tissue Complication Probability (NTCP) in the spinal cord, for given treatment dose and time, the concept of incomplete repair in the Linear Quadratic (LQ) model is generalized. An exact solution is found for the case when the IFIs are all equal.

Original languageEnglish (US)
Title of host publicationAnnual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings
EditorsJ.D. Enderle
Pages706-709
Number of pages4
Volume1
StatePublished - 2000
Externally publishedYes
Event22nd Annual International Conference of the IEEE Engineering in Medicine and Biology Society - Chicago, IL, United States
Duration: Jul 23 2000Jul 28 2000

Other

Other22nd Annual International Conference of the IEEE Engineering in Medicine and Biology Society
CountryUnited States
CityChicago, IL
Period7/23/007/28/00

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Repair
Tissue

Keywords

  • Incomplete repair
  • Mathematical models
  • Normal tissue complication probability

ASJC Scopus subject areas

  • Bioengineering

Cite this

Levin-Plotnik, D., Hamilton, R. J., Niemierko, A., & Akselrod, S. (2000). A model for optimizing normal tissue complication probability in the spinal cord using a generalized incomplete repair scheme. In J. D. Enderle (Ed.), Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings (Vol. 1, pp. 706-709)

A model for optimizing normal tissue complication probability in the spinal cord using a generalized incomplete repair scheme. / Levin-Plotnik, D.; Hamilton, Russell J; Niemierko, A.; Akselrod, S.

Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings. ed. / J.D. Enderle. Vol. 1 2000. p. 706-709.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Levin-Plotnik, D, Hamilton, RJ, Niemierko, A & Akselrod, S 2000, A model for optimizing normal tissue complication probability in the spinal cord using a generalized incomplete repair scheme. in JD Enderle (ed.), Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings. vol. 1, pp. 706-709, 22nd Annual International Conference of the IEEE Engineering in Medicine and Biology Society, Chicago, IL, United States, 7/23/00.
Levin-Plotnik D, Hamilton RJ, Niemierko A, Akselrod S. A model for optimizing normal tissue complication probability in the spinal cord using a generalized incomplete repair scheme. In Enderle JD, editor, Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings. Vol. 1. 2000. p. 706-709
Levin-Plotnik, D. ; Hamilton, Russell J ; Niemierko, A. ; Akselrod, S. / A model for optimizing normal tissue complication probability in the spinal cord using a generalized incomplete repair scheme. Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings. editor / J.D. Enderle. Vol. 1 2000. pp. 706-709
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