A model for optimizing normal tissue complication probability in the spinal cord using a generalized incomplete repair scheme

D. Levin-Plotnik, R. J. Hamilton, A. Niemierko, S. Akselrod

Research output: Contribution to journalArticle

Abstract

To determine the dose fraction sizes and interfraction intervals (IFIs) that minimize the Normal Tissue Complication Probability (NTCP) in the spinal cord, for given treatment dose and time, the concept of incomplete repair in the Linear Quadratic (LQ) model is generalized. An exact solution is found for the case when the IFIs are all equal.

Original languageEnglish (US)
Pages (from-to)706-709
Number of pages4
JournalAnnual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings
Volume1
DOIs
StatePublished - Jan 1 2000
Externally publishedYes

Keywords

  • Incomplete repair
  • Mathematical models
  • Normal tissue complication probability

ASJC Scopus subject areas

  • Signal Processing
  • Biomedical Engineering
  • Computer Vision and Pattern Recognition
  • Health Informatics

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