A network of rice genes associated with stress response and seed development

Bret Cooper, Joseph D. Clarke, Paul Budworth, Joel Kreps, Don Hutchison, Sylvia Park, Sonia Guimil, Molly Dunn, Peter Luginbühl, Cinzia Ellero, Stephen A. Goff, Jane Glazebrook

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181 Scopus citations

Abstract

We used a systematic approach to build a network of genes associated with developmental and stress responses in rice by identifying interaction domains for 200 proteins from stressed and developing tissues, by measuring the associated gene expression changes in different tissues exposed to a variety of environmental, biological, and chemical stress treatments, and by localizing the cognate genes to regions of stress-tolerance trait genetic loci. The integrated data set suggests that similar genes respond to environmental cues and stresses, and some may also regulate development. We demonstrate that the data can be used to correctly predict gene function in monocots and dicots. As a result, we have identified five genes that contribute to disease resistance in Arabidopsis.

Original languageEnglish (US)
Pages (from-to)4945-4950
Number of pages6
JournalProceedings of the National Academy of Sciences of the United States of America
Volume100
Issue number8
DOIs
StatePublished - Apr 15 2003

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Cooper, B., Clarke, J. D., Budworth, P., Kreps, J., Hutchison, D., Park, S., Guimil, S., Dunn, M., Luginbühl, P., Ellero, C., Goff, S. A., & Glazebrook, J. (2003). A network of rice genes associated with stress response and seed development. Proceedings of the National Academy of Sciences of the United States of America, 100(8), 4945-4950. https://doi.org/10.1073/pnas.0737574100