A rapid, sensitive method for quantifying enflurane in whole blood

M. S. Miller, A. J. Gandolfi

Research output: Contribution to journalArticle

34 Scopus citations

Abstract

Thermal conductivity detection (TCD) in conjunction with gas-liquid chromatography was employed for the analysis of enflurane in n-heptane extracts of whole blood. Enflurane was estimated to be 98 per cent extracted from whole blood by n-heptane. Analysis of enflurane standards ranging in concentration from 4.1 to 813 μM demonstrated linearity, with a correlation coefficient of 0.9999. As little as 8 μM enflurane may be detected in whole blood. TCD gas-liquid chromatography is a rapid and sensitive method for quantifying enflurane in whole blood.

Original languageEnglish (US)
Pages (from-to)542-544
Number of pages3
JournalAnesthesiology
Volume51
Issue number6
DOIs
StatePublished - Jan 1 1979

ASJC Scopus subject areas

  • Anesthesiology and Pain Medicine

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