A role for right medial prefrontal cortex in accurate feeling-of-knowing judgments

Evidence from patients with lesions to frontal cortex

David M. Schnyer, Mieke Verfaellie, Michael P. Alexander, Ginette LaFleche, Lindsay Nicholls, Alfred W Kaszniak

Research output: Contribution to journalArticle

126 Citations (Scopus)

Abstract

The hypothesis that prefrontal cortex plays a critical role in accurate predictions of episodic memory performance was tested using the feeling-of-knowing (FOK) paradigm. Fourteen patients with a broad spectrum of damage to the frontal cortex and matched controls read sentences and later were tested for recall memory, confidence judgments, and FOK accuracy using as cues the sentences with the final word missing. While frontal patients were impaired at recall and recognition memory, they were able to make accurate confidence judgments about their recall attempts. By contrast, as a group, the patients were markedly impaired in the accuracy of their prospective FOK judgments. Lesion analysis of frontal patients with clear FOK impairment revealed an overlapping region of damage in right medial prefrontal cortex. These findings provide functional and anatomical evidence for a dissociation between recall confidence and prospective memory monitoring and are discussed in terms of familiarity and access theories of FOK predictions.

Original languageEnglish (US)
Pages (from-to)957-966
Number of pages10
JournalNeuropsychologia
Volume42
Issue number7
DOIs
StatePublished - 2004

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Frontal Lobe
Prefrontal Cortex
Emotions
Episodic Memory
Cues
Recognition (Psychology)

Keywords

  • Feeling-of-knowing
  • Frontal injury
  • Memory monitoring
  • Metamemory

ASJC Scopus subject areas

  • Behavioral Neuroscience
  • Neuropsychology and Physiological Psychology

Cite this

A role for right medial prefrontal cortex in accurate feeling-of-knowing judgments : Evidence from patients with lesions to frontal cortex. / Schnyer, David M.; Verfaellie, Mieke; Alexander, Michael P.; LaFleche, Ginette; Nicholls, Lindsay; Kaszniak, Alfred W.

In: Neuropsychologia, Vol. 42, No. 7, 2004, p. 957-966.

Research output: Contribution to journalArticle

Schnyer, David M. ; Verfaellie, Mieke ; Alexander, Michael P. ; LaFleche, Ginette ; Nicholls, Lindsay ; Kaszniak, Alfred W. / A role for right medial prefrontal cortex in accurate feeling-of-knowing judgments : Evidence from patients with lesions to frontal cortex. In: Neuropsychologia. 2004 ; Vol. 42, No. 7. pp. 957-966.
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