A sensitive radioenzymatic assay for norepinephrine in tissues and plasma

David P. Henry, Barbra J. Starman, David G. Johnson, Robert H. Williams

Research output: Contribution to journalArticle

399 Scopus citations

Abstract

A procedure for measuring picogram quantities of norepinephrine has been developed utilizing partially purified bovine adrenal phenylethanolamine-N-methyl-transferase and 3[H]-S-adenosyl-methionine. The sensitivity of the assay is 25 pg, and the procedure is applicable to many body tissues and fluids, including brain and plasma.

Original languageEnglish (US)
Pages (from-to)375-384
Number of pages10
JournalLife Sciences
Volume16
Issue number3
DOIs
StatePublished - Feb 1 1975
Externally publishedYes

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)
  • Pharmacology, Toxicology and Pharmaceutics(all)

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