Abnormal iris vasculature in myotonic dystrophy. An anterior segment angiographic study

L. Z. Stern, Harold E Cross, A. R. Crebo

Research output: Contribution to journalArticle

13 Citations (Scopus)

Abstract

The microvasculature of the iris was studied in 35 patients with neuromuscular disease and 14 control subjects, using anterior segment fluorescein angiography. Myotonic muscular dystrophy, in which a variety of ocular changes have previously been reported, was found to be associated with both focal and generalized vascular abnormalities. Changes were seen in the fluorescein angiograms of all 9 of the myotonic dystrophy patients in which the iris vessels could be seen. No evidence of a microcirculatory disorder was seen in patients with Duchenne dystrophy, for which a vascular pathogenesis has been proposed. The angiograms of patients with limb-girdle dystrophy, facioscapulohumeral dystrophy and Friedreich's ataxia were also normal.

Original languageEnglish (US)
Pages (from-to)224-227
Number of pages4
JournalArchives of Neurology
Volume35
Issue number4
StatePublished - 1978

Fingerprint

Myotonic Dystrophy
Iris
Blood Vessels
Angiography
Friedreich Ataxia
Neuromuscular Diseases
Muscular Dystrophies
Fluorescein Angiography
Microvessels
Fluorescein
Extremities

ASJC Scopus subject areas

  • Neuroscience(all)

Cite this

Abnormal iris vasculature in myotonic dystrophy. An anterior segment angiographic study. / Stern, L. Z.; Cross, Harold E; Crebo, A. R.

In: Archives of Neurology, Vol. 35, No. 4, 1978, p. 224-227.

Research output: Contribution to journalArticle

@article{3b6ea30e5df548e882bd2fd1d43b0d80,
title = "Abnormal iris vasculature in myotonic dystrophy. An anterior segment angiographic study",
abstract = "The microvasculature of the iris was studied in 35 patients with neuromuscular disease and 14 control subjects, using anterior segment fluorescein angiography. Myotonic muscular dystrophy, in which a variety of ocular changes have previously been reported, was found to be associated with both focal and generalized vascular abnormalities. Changes were seen in the fluorescein angiograms of all 9 of the myotonic dystrophy patients in which the iris vessels could be seen. No evidence of a microcirculatory disorder was seen in patients with Duchenne dystrophy, for which a vascular pathogenesis has been proposed. The angiograms of patients with limb-girdle dystrophy, facioscapulohumeral dystrophy and Friedreich's ataxia were also normal.",
author = "Stern, {L. Z.} and Cross, {Harold E} and Crebo, {A. R.}",
year = "1978",
language = "English (US)",
volume = "35",
pages = "224--227",
journal = "Archives of Neurology",
issn = "0003-9942",
publisher = "American Medical Association",
number = "4",

}

TY - JOUR

T1 - Abnormal iris vasculature in myotonic dystrophy. An anterior segment angiographic study

AU - Stern, L. Z.

AU - Cross, Harold E

AU - Crebo, A. R.

PY - 1978

Y1 - 1978

N2 - The microvasculature of the iris was studied in 35 patients with neuromuscular disease and 14 control subjects, using anterior segment fluorescein angiography. Myotonic muscular dystrophy, in which a variety of ocular changes have previously been reported, was found to be associated with both focal and generalized vascular abnormalities. Changes were seen in the fluorescein angiograms of all 9 of the myotonic dystrophy patients in which the iris vessels could be seen. No evidence of a microcirculatory disorder was seen in patients with Duchenne dystrophy, for which a vascular pathogenesis has been proposed. The angiograms of patients with limb-girdle dystrophy, facioscapulohumeral dystrophy and Friedreich's ataxia were also normal.

AB - The microvasculature of the iris was studied in 35 patients with neuromuscular disease and 14 control subjects, using anterior segment fluorescein angiography. Myotonic muscular dystrophy, in which a variety of ocular changes have previously been reported, was found to be associated with both focal and generalized vascular abnormalities. Changes were seen in the fluorescein angiograms of all 9 of the myotonic dystrophy patients in which the iris vessels could be seen. No evidence of a microcirculatory disorder was seen in patients with Duchenne dystrophy, for which a vascular pathogenesis has been proposed. The angiograms of patients with limb-girdle dystrophy, facioscapulohumeral dystrophy and Friedreich's ataxia were also normal.

UR - http://www.scopus.com/inward/record.url?scp=0017799369&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0017799369&partnerID=8YFLogxK

M3 - Article

C2 - 637756

AN - SCOPUS:0017799369

VL - 35

SP - 224

EP - 227

JO - Archives of Neurology

JF - Archives of Neurology

SN - 0003-9942

IS - 4

ER -