Abnormal myocardial capillary perfusion with normal coronary arteries and valvular heart disease

Steven Goldman, W. David Hager, James M. Woolfenden, Bertron M. Groves, Kenneth L. Raessler, Dennis D. Patton, Frank I. Marcus

Research output: Contribution to journalArticle

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The demonstration of normal coronary arteries at cardiac catheterization has been considered adequate definition of normal myocardial perfusion. To examine this, we have utilized intracoronary injections of technetium-99m labeled albumin microspheres in 11 patients with valvular heart disease, and in 13 patients with chest pain syndrome or constrictive pericarditis. Eight patients with valvular heart disease had large, patchy, irregular perfusion deficits noted on the scintiphotos. Only one of thirteen control patients had a perfusion deficit. Caution, therefore, must be used in attributing such perfusion deficits to atherosclerotic disease when valvular disease is present.

Original languageEnglish (US)
Pages (from-to)259-265
Number of pages7
JournalInternational Journal of Nuclear Medicine and Biology
Issue number3
StatePublished - 1980


ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

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