AC Electrokinetics of Physiological Fluids for Biomedical Applications

Yi Lu, Tingting Liu, Ariana C. Lamanda, Mandy L Y Sin, Vincent Gau, Joseph C. Liao, Pak Kin Wong

Research output: Contribution to journalArticle

19 Scopus citations

Abstract

Alternating current (AC) electrokinetics is a collection of processes for manipulating bulk fluid mass and embedded objects with AC electric fields. The ability of AC electrokinetics to implement the major microfluidic operations, such as pumping, mixing, concentration, and separation, makes it possible to develop integrated systems for clinical diagnostics in nontraditional health care settings. The high conductivity of physiological fluids presents new challenges and opportunities for AC electrokinetics–based diagnostic systems. In this review, AC electrokinetic phenomena in conductive physiological fluids are described followed by a review of the basic microfluidic operations and the recent biomedical applications of AC electrokinetics. The future prospects of AC electrokinetics for clinical diagnostics are presented.

Original languageEnglish (US)
Pages (from-to)611-620
Number of pages10
JournalJournal of laboratory automation
Volume20
Issue number6
DOIs
StatePublished - Dec 1 2015

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Keywords

  • electrokinetics
  • electrothermal flow
  • microfluidics
  • physiological fluid
  • point-of-care diagnostics

ASJC Scopus subject areas

  • Computer Science Applications
  • Medical Laboratory Technology

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