Accumulation of myosin, actin, tropomyosin, and α-actinin in cultured muscle cells

Ronald E. Allen, Marvin H. Stromer, Darrel E. Goll, Richard M. Robson

Research output: Contribution to journalArticle

9 Scopus citations

Abstract

In an effort to understand the conditions that promote the assembly of myofibrillar proteins in muscle cells, the temporal sequence of accumulation of four myofibrillar proteins, actin, myosin, tropomyosin, and α-actinin, was monitored during the period of de novo assembly of myofibrils in differentiating muscle cells. Isotope dilution experiments indicated that all four proteins were accumulated simultaneously. Therefore, assembly of myofibrils may be occurring in the presence of a full complement of myofibrillar proteins.

Original languageEnglish (US)
Pages (from-to)655-660
Number of pages6
JournalDevelopmental biology
Volume69
Issue number2
DOIs
StatePublished - Apr 1979
Externally publishedYes

ASJC Scopus subject areas

  • Molecular Biology
  • Developmental Biology
  • Cell Biology

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