Accurate determination of quadruplex binding affinity and potency of G-quadruplex-interactive telomerase inhibitors by use of a telomerase extension assay requires varying the primer concentration

Brian E. Cathers, Daekyu Sun, Laurence H. Hurley

Research output: Contribution to journalShort surveypeer-review

12 Scopus citations
Original languageEnglish (US)
Pages (from-to)367-372
Number of pages6
JournalAnti-Cancer Drug Design
Volume14
Issue number4
StatePublished - Aug 1 1999
Externally publishedYes

Keywords

  • Anthraquinone
  • Assay
  • G-quadruplex
  • Inhibition
  • Telomerase

ASJC Scopus subject areas

  • Biochemistry
  • Oncology
  • Biochemistry, Genetics and Molecular Biology(all)
  • Pharmacology
  • Drug Discovery
  • Organic Chemistry

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