Acoustoelectric detection of current flow in a neural recording chamber

Russell S Witte, R. Olafsson, M. O'Donnell

Research output: Chapter in Book/Report/Conference proceedingConference contribution

10 Citations (Scopus)

Abstract

Acoustic pressure (P) traveling in a biologic fluid or tissue generates a local change in electrical conductivity. This acoustoelectric interaction (AE) induces a voltage modulation that depends on local current, resistance, and pressure. We explore the AE signal as a way to enhance traditional electrophysiology or surface recording of neural signals. A thin stretch tube mimicking an enlarged axon and an abdominal segment of a fresh lobster nerve cord were used as test structures for AE detection in a tri-compartment neural recording chamber. Stimulating electrodes passed low frequency current through the structures, while a pair of recording electrodes detected the high frequency AE signal. Ultrasound transducers from 0.5 to 7.5 MHz delivered P up to 2 MPa. The differentially-recorded AE signal was captured on a fast data acquisition board and saved for post processing. In the lobster nerve cord, the AE signal was linear between the tested range of current densities of 9 to 86 mA/cm 2 [18 dB/log(J), r2=0.96] and P of 0.5 to 2 MPa [21 dB/log(P), r2=0.96]. In addition, a transverse scan of the structures produced cross-sectional AE images of current flow with remote detection by the recording electrodes. Results were consistent with AE simulations. This study demonstrates that the AE signal can be used to detect and image current flow in a biologic environment with physiologically-relevant current densities and acoustic pressures on par with clinical ultrasound imaging.

Original languageEnglish (US)
Title of host publicationProceedings - IEEE Ultrasonics Symposium
Pages5-8
Number of pages4
Volume1
DOIs
StatePublished - 2006
Externally publishedYes
Event2006 IEEE International Ultrasonics Symposium, IUS - Vancouver, BC, Canada
Duration: Oct 3 2006Oct 6 2006

Other

Other2006 IEEE International Ultrasonics Symposium, IUS
CountryCanada
CityVancouver, BC
Period10/3/0610/6/06

Fingerprint

chambers
recording
Electrodes
Current density
Ultrasonics
Acoustics
Electrophysiology
interactions
Transducers
Data acquisition
Modulation
nerves
Tissue
Imaging techniques
Fluids
electrodes
Electric potential
Processing
electrophysiology
current density

ASJC Scopus subject areas

  • Engineering(all)
  • Acoustics and Ultrasonics

Cite this

Witte, R. S., Olafsson, R., & O'Donnell, M. (2006). Acoustoelectric detection of current flow in a neural recording chamber. In Proceedings - IEEE Ultrasonics Symposium (Vol. 1, pp. 5-8). [4151872] https://doi.org/10.1109/ULTSYM.2006.16

Acoustoelectric detection of current flow in a neural recording chamber. / Witte, Russell S; Olafsson, R.; O'Donnell, M.

Proceedings - IEEE Ultrasonics Symposium. Vol. 1 2006. p. 5-8 4151872.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Witte, RS, Olafsson, R & O'Donnell, M 2006, Acoustoelectric detection of current flow in a neural recording chamber. in Proceedings - IEEE Ultrasonics Symposium. vol. 1, 4151872, pp. 5-8, 2006 IEEE International Ultrasonics Symposium, IUS, Vancouver, BC, Canada, 10/3/06. https://doi.org/10.1109/ULTSYM.2006.16
Witte RS, Olafsson R, O'Donnell M. Acoustoelectric detection of current flow in a neural recording chamber. In Proceedings - IEEE Ultrasonics Symposium. Vol. 1. 2006. p. 5-8. 4151872 https://doi.org/10.1109/ULTSYM.2006.16
Witte, Russell S ; Olafsson, R. ; O'Donnell, M. / Acoustoelectric detection of current flow in a neural recording chamber. Proceedings - IEEE Ultrasonics Symposium. Vol. 1 2006. pp. 5-8
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