Acoustoelectric imaging of time-varying current produced by a clinical deep brain stimulator

Chet Preston; Yexian Qin; Alex Burton; Pier Ingram; Willard Kasoff; Russell S Witte

doi:10.1109/ULTSYM.2017.8092105

Acoustoelectric imaging of time-varying current produced by a clinical deep brain stimulator

Chet Preston, Yexian Qin, Alex Burton, Pier Ingram, Willard Kasoff, Russell S Witte

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

1 Scopus citations

Abstract

Deep brain stimulation (DBS) is an effective therapy for dyskinesia associated with treatments for Parkinson's disease (PD). While current surgical placement of a DBS implant depends on stereotactic coordinates with computed tomography and magnetic resonance imaging for precise localization of the electrode sites, the actual current densities produced by the DBS are not directly observed. This study proposes a novel ultrasound (US) method to visualize these current distributions produced by a DBS via acoustoelectric (AE) imaging. AE imaging uses a focused US beam to locally modulate tissue resistivity due to the AE effect, producing a detectable oscillating voltage from a current flow. The primary goal for this study is to assess baseline performance of AE technology for detecting and resolving current densities near a DBS implant using clinically-relevant stimulation parameters.

Original language	English (US)
Title of host publication	2017 IEEE International Ultrasonics Symposium, IUS 2017
Publisher	IEEE Computer Society
ISBN (Electronic)	9781538633830
DOIs	https://doi.org/10.1109/ULTSYM.2017.8092105
State	Published - Oct 31 2017
Event	2017 IEEE International Ultrasonics Symposium, IUS 2017 - Washington, United States Duration: Sep 6 2017 → Sep 9 2017

Other

Other	2017 IEEE International Ultrasonics Symposium, IUS 2017
Country/Territory	United States
City	Washington
Period	9/6/17 → 9/9/17

ASJC Scopus subject areas

Acoustics and Ultrasonics

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10.1109/ULTSYM.2017.8092105

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Acoustoelectric imaging of time-varying current produced by a clinical deep brain stimulator. / Preston, Chet; Qin, Yexian; Burton, Alex; Ingram, Pier; Kasoff, Willard ; Witte, Russell S.

2017 IEEE International Ultrasonics Symposium, IUS 2017. IEEE Computer Society, 2017. 8092105.

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Preston, C, Qin, Y, Burton, A, Ingram, P, Kasoff, W & Witte, RS 2017, Acoustoelectric imaging of time-varying current produced by a clinical deep brain stimulator. in 2017 IEEE International Ultrasonics Symposium, IUS 2017., 8092105, IEEE Computer Society, 2017 IEEE International Ultrasonics Symposium, IUS 2017, Washington, United States, 9/6/17. https://doi.org/10.1109/ULTSYM.2017.8092105

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abstract = "Deep brain stimulation (DBS) is an effective therapy for dyskinesia associated with treatments for Parkinson's disease (PD). While current surgical placement of a DBS implant depends on stereotactic coordinates with computed tomography and magnetic resonance imaging for precise localization of the electrode sites, the actual current densities produced by the DBS are not directly observed. This study proposes a novel ultrasound (US) method to visualize these current distributions produced by a DBS via acoustoelectric (AE) imaging. AE imaging uses a focused US beam to locally modulate tissue resistivity due to the AE effect, producing a detectable oscillating voltage from a current flow. The primary goal for this study is to assess baseline performance of AE technology for detecting and resolving current densities near a DBS implant using clinically-relevant stimulation parameters.",

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AB - Deep brain stimulation (DBS) is an effective therapy for dyskinesia associated with treatments for Parkinson's disease (PD). While current surgical placement of a DBS implant depends on stereotactic coordinates with computed tomography and magnetic resonance imaging for precise localization of the electrode sites, the actual current densities produced by the DBS are not directly observed. This study proposes a novel ultrasound (US) method to visualize these current distributions produced by a DBS via acoustoelectric (AE) imaging. AE imaging uses a focused US beam to locally modulate tissue resistivity due to the AE effect, producing a detectable oscillating voltage from a current flow. The primary goal for this study is to assess baseline performance of AE technology for detecting and resolving current densities near a DBS implant using clinically-relevant stimulation parameters.

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Acoustoelectric imaging of time-varying current produced by a clinical deep brain stimulator

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