Acoustoelectric imaging of time-varying current produced by a clinical deep brain stimulator

Chet Preston, Yexian Qin, Alex Burton, Pier Ingram, Willard Kasoff, Russell S Witte

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

Deep brain stimulation (DBS) is an effective therapy for dyskinesia associated with treatments for Parkinson's disease (PD). While current surgical placement of a DBS implant depends on stereotactic coordinates with computed tomography and magnetic resonance imaging for precise localization of the electrode sites, the actual current densities produced by the DBS are not directly observed. This study proposes a novel ultrasound (US) method to visualize these current distributions produced by a DBS via acoustoelectric (AE) imaging. AE imaging uses a focused US beam to locally modulate tissue resistivity due to the AE effect, producing a detectable oscillating voltage from a current flow. The primary goal for this study is to assess baseline performance of AE technology for detecting and resolving current densities near a DBS implant using clinically-relevant stimulation parameters.

Original languageEnglish (US)
Title of host publication2017 IEEE International Ultrasonics Symposium, IUS 2017
PublisherIEEE Computer Society
ISBN (Electronic)9781538633830
DOIs
StatePublished - Oct 31 2017
Event2017 IEEE International Ultrasonics Symposium, IUS 2017 - Washington, United States
Duration: Sep 6 2017Sep 9 2017

Other

Other2017 IEEE International Ultrasonics Symposium, IUS 2017
CountryUnited States
CityWashington
Period9/6/179/9/17

Fingerprint

stimulation
brain
Parkinson disease
current density
current distribution
magnetic resonance
therapy
tomography
electrical resistivity
electrodes
electric potential

ASJC Scopus subject areas

  • Acoustics and Ultrasonics

Cite this

Preston, C., Qin, Y., Burton, A., Ingram, P., Kasoff, W., & Witte, R. S. (2017). Acoustoelectric imaging of time-varying current produced by a clinical deep brain stimulator. In 2017 IEEE International Ultrasonics Symposium, IUS 2017 [8092105] IEEE Computer Society. https://doi.org/10.1109/ULTSYM.2017.8092105

Acoustoelectric imaging of time-varying current produced by a clinical deep brain stimulator. / Preston, Chet; Qin, Yexian; Burton, Alex; Ingram, Pier; Kasoff, Willard; Witte, Russell S.

2017 IEEE International Ultrasonics Symposium, IUS 2017. IEEE Computer Society, 2017. 8092105.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Preston, C, Qin, Y, Burton, A, Ingram, P, Kasoff, W & Witte, RS 2017, Acoustoelectric imaging of time-varying current produced by a clinical deep brain stimulator. in 2017 IEEE International Ultrasonics Symposium, IUS 2017., 8092105, IEEE Computer Society, 2017 IEEE International Ultrasonics Symposium, IUS 2017, Washington, United States, 9/6/17. https://doi.org/10.1109/ULTSYM.2017.8092105
Preston C, Qin Y, Burton A, Ingram P, Kasoff W, Witte RS. Acoustoelectric imaging of time-varying current produced by a clinical deep brain stimulator. In 2017 IEEE International Ultrasonics Symposium, IUS 2017. IEEE Computer Society. 2017. 8092105 https://doi.org/10.1109/ULTSYM.2017.8092105
Preston, Chet ; Qin, Yexian ; Burton, Alex ; Ingram, Pier ; Kasoff, Willard ; Witte, Russell S. / Acoustoelectric imaging of time-varying current produced by a clinical deep brain stimulator. 2017 IEEE International Ultrasonics Symposium, IUS 2017. IEEE Computer Society, 2017.
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