Activation of sphingosine-1-phosphate receptor subtype 1 in the central nervous system contributes to morphine-induced hyperalgesia and antinociceptive tolerance in rodents

Timothy M. Doyle, Kali Janes, Zhoumou Chen, Peter M. Grace, Emanuela Esposito, Salvatore Cuzzocrea, Tally M. Largent-Milnes, William L. Neumann, Linda R. Watkins, Sarah Spiegel, Todd W. Vanderah, Daniela Salvemini

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