Activity-based high-throughput profiling of metalloprotease inhibitors using small molecule microarrays

Jun Wang, Mahesh Uttamchandani, Ping Sun Li, Shao Q. Yao

Research output: Contribution to journalArticle

23 Citations (Scopus)

Abstract

We herein describe a high-throughput small molecule microarray (SMM) method that enables quick and cost-effective identification of potent inhibitors of metalloproteases in an activity-dependent manner, thereby offering a rapid means for inhibitor discovery and profiling.

Original languageEnglish (US)
Pages (from-to)717-719
Number of pages3
JournalChemical Communications
Issue number7
DOIs
StatePublished - 2006
Externally publishedYes

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Metalloproteases
Microarrays
Throughput
Molecules
Costs

ASJC Scopus subject areas

  • Chemistry(all)

Cite this

Activity-based high-throughput profiling of metalloprotease inhibitors using small molecule microarrays. / Wang, Jun; Uttamchandani, Mahesh; Li, Ping Sun; Yao, Shao Q.

In: Chemical Communications, No. 7, 2006, p. 717-719.

Research output: Contribution to journalArticle

Wang, Jun ; Uttamchandani, Mahesh ; Li, Ping Sun ; Yao, Shao Q. / Activity-based high-throughput profiling of metalloprotease inhibitors using small molecule microarrays. In: Chemical Communications. 2006 ; No. 7. pp. 717-719.
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