Activity-based high-throughput profiling of metalloprotease inhibitors using small molecule microarrays

Jun Wang, Mahesh Uttamchandani, Ping Sun Li, Shao Q. Yao

Research output: Contribution to journalArticlepeer-review

24 Scopus citations

Abstract

We herein describe a high-throughput small molecule microarray (SMM) method that enables quick and cost-effective identification of potent inhibitors of metalloproteases in an activity-dependent manner, thereby offering a rapid means for inhibitor discovery and profiling.

Original languageEnglish (US)
Pages (from-to)717-719
Number of pages3
JournalChemical Communications
Issue number7
DOIs
StatePublished - Feb 22 2006
Externally publishedYes

ASJC Scopus subject areas

  • Catalysis
  • Electronic, Optical and Magnetic Materials
  • Ceramics and Composites
  • Chemistry(all)
  • Surfaces, Coatings and Films
  • Metals and Alloys
  • Materials Chemistry

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