Acular as a single agent for use as an antimiotic and anti-inflammatory in cataract surgery

Robert W. Snyder, Rand W. Siekert, Jim Schwiegerling, Eric Donnenfeld, Pam Thompson

Research output: Contribution to journalArticle

20 Scopus citations

Abstract

Purpose: To assess the safety and effectiveness of ketorolac tromethamine 0.5% (Acular®) as a cost-efficient single agent to prevent intraoperative miosis and postoperative inflammation in cataract surgery. Methods: Both eyes of 26 patients were randomized to receive Acular preoperatively and postoperatively or flurbiprofen sodium (Ocufen®) preoperatively and prednisolone acetate 1% (Pred Forte®) postoperatively. Time scheduled between procedures was from 2 weeks to 1 month. Pupil dilation was measured preoperatively, intraoperatively, and at the end of surgery. Cell and flare were measured 1 day, 1 week, and 1 month postoperatively. Results: A comparison of the Acular and the Ocufen/Pred Forte groups (n=22) showed no statistically significant differences in dilation (preoperative versus postpostoperative) or cell and flare postoperatively. Conclusion: Using Acular as a single agent was as effective as the combination of preoperative Ocufen and postoperative Pred Forte in preventing intraoperative miosis and postoperative inflammation in cataract surgery. The use of Acular as a single agent could save the expense of using separate anti-inflammatory and antimiotic preparations preoperatively and postoperatively, enhancing convenience for the surgeon and surgical facility. (C) 2000 ASCRS and ESCRS.

Original languageEnglish (US)
Pages (from-to)1225-1227
Number of pages3
JournalJournal of Cataract and Refractive Surgery
Volume26
Issue number8
DOIs
StatePublished - Oct 9 2000

ASJC Scopus subject areas

  • Surgery
  • Ophthalmology
  • Sensory Systems

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