Acute and chronic morphine effects on plasma corticosteroids and growth hormone in the cat

Edward D French, Joseph F. Garcia, Robert George

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

(1) Low doses of intravenous morphine in the cat caused an elevation of both corticosteroid and growth hormone in plasma. (2) Corticosteroid levels did not continue to increase in concert with the dose of morphine but the level of growth hormone did. (3) Tolerance developed to the effects of morphine on corticosteroids but not to the effect on growth hormone. (4) Naloxone precipitated withdrawal was associated with an increase in plasma corticosteroid but not growth hormone.

Original languageEnglish (US)
Pages (from-to)237-244
Number of pages8
JournalPsychoneuroendocrinology
Volume3
Issue number3-4
DOIs
StatePublished - 1978
Externally publishedYes

Fingerprint

Morphine
Growth Hormone
Adrenal Cortex Hormones
Cats
Naloxone

Keywords

  • cat
  • corticosteroids
  • growth hormone
  • morphine

ASJC Scopus subject areas

  • Endocrinology
  • Endocrinology, Diabetes and Metabolism
  • Psychiatry and Mental health
  • Biological Psychiatry
  • Endocrine and Autonomic Systems
  • Psychology(all)

Cite this

Acute and chronic morphine effects on plasma corticosteroids and growth hormone in the cat. / French, Edward D; Garcia, Joseph F.; George, Robert.

In: Psychoneuroendocrinology, Vol. 3, No. 3-4, 1978, p. 237-244.

Research output: Contribution to journalArticle

@article{1bca113cce5e4f0fb9b7f6fa41043bbd,
title = "Acute and chronic morphine effects on plasma corticosteroids and growth hormone in the cat",
abstract = "(1) Low doses of intravenous morphine in the cat caused an elevation of both corticosteroid and growth hormone in plasma. (2) Corticosteroid levels did not continue to increase in concert with the dose of morphine but the level of growth hormone did. (3) Tolerance developed to the effects of morphine on corticosteroids but not to the effect on growth hormone. (4) Naloxone precipitated withdrawal was associated with an increase in plasma corticosteroid but not growth hormone.",
keywords = "cat, corticosteroids, growth hormone, morphine",
author = "French, {Edward D} and Garcia, {Joseph F.} and Robert George",
year = "1978",
doi = "10.1016/0306-4530(78)90014-8",
language = "English (US)",
volume = "3",
pages = "237--244",
journal = "Psychoneuroendocrinology",
issn = "0306-4530",
publisher = "Elsevier Limited",
number = "3-4",

}

TY - JOUR

T1 - Acute and chronic morphine effects on plasma corticosteroids and growth hormone in the cat

AU - French, Edward D

AU - Garcia, Joseph F.

AU - George, Robert

PY - 1978

Y1 - 1978

N2 - (1) Low doses of intravenous morphine in the cat caused an elevation of both corticosteroid and growth hormone in plasma. (2) Corticosteroid levels did not continue to increase in concert with the dose of morphine but the level of growth hormone did. (3) Tolerance developed to the effects of morphine on corticosteroids but not to the effect on growth hormone. (4) Naloxone precipitated withdrawal was associated with an increase in plasma corticosteroid but not growth hormone.

AB - (1) Low doses of intravenous morphine in the cat caused an elevation of both corticosteroid and growth hormone in plasma. (2) Corticosteroid levels did not continue to increase in concert with the dose of morphine but the level of growth hormone did. (3) Tolerance developed to the effects of morphine on corticosteroids but not to the effect on growth hormone. (4) Naloxone precipitated withdrawal was associated with an increase in plasma corticosteroid but not growth hormone.

KW - cat

KW - corticosteroids

KW - growth hormone

KW - morphine

UR - http://www.scopus.com/inward/record.url?scp=0018245728&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0018245728&partnerID=8YFLogxK

U2 - 10.1016/0306-4530(78)90014-8

DO - 10.1016/0306-4530(78)90014-8

M3 - Article

C2 - 571128

AN - SCOPUS:0018245728

VL - 3

SP - 237

EP - 244

JO - Psychoneuroendocrinology

JF - Psychoneuroendocrinology

SN - 0306-4530

IS - 3-4

ER -