Acute renal failure and type B lactic acidosis as first manifestation of extranodal T-cell lymphoblastic lymphoma

Seongseok Yun, Courtney N. Walker, Nicole D. Vincelette, Faiz - Anwer

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

We describe a rare case of a 19-year-old male patient with a history of epilepsy and developmental delay who presented with acute renal failure (ARF) and lactic acidosis (LA) as the first manifestation of T-cell lymphoblastic lymphoma. Renal ultrasound and CT of the abdomen showed renal parenchymal infiltration, and renal biopsy demonstrated T-cell lymphoblastic lymphoma. LA, ARF and electrolyte abnormalities were refractory to the initial treatment of bicarbonate infusion and hydration. However, these abnormalities rapidly normalised after the initiation of chemotherapy, suggesting that the LA and ARF were secondary to lymphomatous renal infiltration.

Original languageEnglish (US)
JournalBMJ Case Reports
DOIs
StatePublished - Jun 9 2014

Fingerprint

Lactic Acidosis
T-Cell Lymphoma
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Acute Kidney Injury
Kidney
Bicarbonates
Abdomen
Electrolytes
Epilepsy
Biopsy
Drug Therapy
Therapeutics

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Acute renal failure and type B lactic acidosis as first manifestation of extranodal T-cell lymphoblastic lymphoma. / Yun, Seongseok; Walker, Courtney N.; Vincelette, Nicole D.; Anwer, Faiz -.

In: BMJ Case Reports, 09.06.2014.

Research output: Contribution to journalArticle

@article{edbbb4bb85234321b89d04d617a606d1,
title = "Acute renal failure and type B lactic acidosis as first manifestation of extranodal T-cell lymphoblastic lymphoma",
abstract = "We describe a rare case of a 19-year-old male patient with a history of epilepsy and developmental delay who presented with acute renal failure (ARF) and lactic acidosis (LA) as the first manifestation of T-cell lymphoblastic lymphoma. Renal ultrasound and CT of the abdomen showed renal parenchymal infiltration, and renal biopsy demonstrated T-cell lymphoblastic lymphoma. LA, ARF and electrolyte abnormalities were refractory to the initial treatment of bicarbonate infusion and hydration. However, these abnormalities rapidly normalised after the initiation of chemotherapy, suggesting that the LA and ARF were secondary to lymphomatous renal infiltration.",
author = "Seongseok Yun and Walker, {Courtney N.} and Vincelette, {Nicole D.} and Anwer, {Faiz -}",
year = "2014",
month = "6",
day = "9",
doi = "10.1136/bcr-2014-205044",
language = "English (US)",
journal = "BMJ Case Reports",
issn = "1757-790X",
publisher = "BMJ Publishing Group",

}

TY - JOUR

T1 - Acute renal failure and type B lactic acidosis as first manifestation of extranodal T-cell lymphoblastic lymphoma

AU - Yun, Seongseok

AU - Walker, Courtney N.

AU - Vincelette, Nicole D.

AU - Anwer, Faiz -

PY - 2014/6/9

Y1 - 2014/6/9

N2 - We describe a rare case of a 19-year-old male patient with a history of epilepsy and developmental delay who presented with acute renal failure (ARF) and lactic acidosis (LA) as the first manifestation of T-cell lymphoblastic lymphoma. Renal ultrasound and CT of the abdomen showed renal parenchymal infiltration, and renal biopsy demonstrated T-cell lymphoblastic lymphoma. LA, ARF and electrolyte abnormalities were refractory to the initial treatment of bicarbonate infusion and hydration. However, these abnormalities rapidly normalised after the initiation of chemotherapy, suggesting that the LA and ARF were secondary to lymphomatous renal infiltration.

AB - We describe a rare case of a 19-year-old male patient with a history of epilepsy and developmental delay who presented with acute renal failure (ARF) and lactic acidosis (LA) as the first manifestation of T-cell lymphoblastic lymphoma. Renal ultrasound and CT of the abdomen showed renal parenchymal infiltration, and renal biopsy demonstrated T-cell lymphoblastic lymphoma. LA, ARF and electrolyte abnormalities were refractory to the initial treatment of bicarbonate infusion and hydration. However, these abnormalities rapidly normalised after the initiation of chemotherapy, suggesting that the LA and ARF were secondary to lymphomatous renal infiltration.

UR - http://www.scopus.com/inward/record.url?scp=84902590220&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84902590220&partnerID=8YFLogxK

U2 - 10.1136/bcr-2014-205044

DO - 10.1136/bcr-2014-205044

M3 - Article

JO - BMJ Case Reports

JF - BMJ Case Reports

SN - 1757-790X

ER -