Adaptation in intestinal transport of D-glucose due to dietary carbohydrate was studied with an in situ perfusion technique. Three groups of 10 rats were fed isocalorically for 7 days, diets with no carbohydrate, glucose or fructose. A segment of jejunum was cannulated and perfused with 14C-glucose to measure absorption. Net transport of glucose was increased 76% upon feeding glucose or fructose compared to no carbohydrate. While carbohydrate feeding is known to induce intestinal disaccharidases such as sucrase and maltase, these results demonstrate that it also enhances the capacity of the intestinal tract to absorb glucose.
- Dietary carbohydrate
- Glucose transport
ASJC Scopus subject areas
- Endocrinology, Diabetes and Metabolism
- Nutrition and Dietetics