ADC estimation of lesions in diffusion-weighted MR images: A maximum-likelihood approach

Abhinav K. Jha, Matthew A Kupinski, Jeffrey J Rodriguez, Renu M. Stephen, Alison T Stopeck

Research output: Chapter in Book/Report/Conference proceedingConference contribution

4 Citations (Scopus)

Abstract

In recent years, the apparent diffusion coefficient (ADC) of lesions obtained using diffusion-weighted magnetic resonance imaging (DWMRI) has emerged as a potentially novel non-invasive imaging bio-marker for prediction and monitoring of anti-cancer therapy response. However, the motion in visceral organs and different variances in DWMRI measurements at different magnetic diffusion gradient values can make ADC estimation a challenging task. We propose a maximum-likelihood method for ADC estimation of lesions in DWMRI. We show through simulations that our method outperforms the standard linear-least-squares and diffusion-map methods.

Original languageEnglish (US)
Title of host publicationProceedings of the IEEE Southwest Symposium on Image Analysis and Interpretation
Pages209-212
Number of pages4
DOIs
StatePublished - 2010
Event2010 IEEE Southwest Symposium on Image Analysis and Interpretation, SSIAI 2010 - Austin, TX, United States
Duration: May 23 2010May 25 2010

Other

Other2010 IEEE Southwest Symposium on Image Analysis and Interpretation, SSIAI 2010
CountryUnited States
CityAustin, TX
Period5/23/105/25/10

Fingerprint

Maximum likelihood
Magnetic resonance
Imaging techniques
Monitoring

ASJC Scopus subject areas

  • Software
  • Computer Vision and Pattern Recognition
  • Computer Science Applications

Cite this

Jha, A. K., Kupinski, M. A., Rodriguez, J. J., Stephen, R. M., & Stopeck, A. T. (2010). ADC estimation of lesions in diffusion-weighted MR images: A maximum-likelihood approach. In Proceedings of the IEEE Southwest Symposium on Image Analysis and Interpretation (pp. 209-212). [5483880] https://doi.org/10.1109/SSIAI.2010.5483880

ADC estimation of lesions in diffusion-weighted MR images : A maximum-likelihood approach. / Jha, Abhinav K.; Kupinski, Matthew A; Rodriguez, Jeffrey J; Stephen, Renu M.; Stopeck, Alison T.

Proceedings of the IEEE Southwest Symposium on Image Analysis and Interpretation. 2010. p. 209-212 5483880.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Jha, AK, Kupinski, MA, Rodriguez, JJ, Stephen, RM & Stopeck, AT 2010, ADC estimation of lesions in diffusion-weighted MR images: A maximum-likelihood approach. in Proceedings of the IEEE Southwest Symposium on Image Analysis and Interpretation., 5483880, pp. 209-212, 2010 IEEE Southwest Symposium on Image Analysis and Interpretation, SSIAI 2010, Austin, TX, United States, 5/23/10. https://doi.org/10.1109/SSIAI.2010.5483880
Jha AK, Kupinski MA, Rodriguez JJ, Stephen RM, Stopeck AT. ADC estimation of lesions in diffusion-weighted MR images: A maximum-likelihood approach. In Proceedings of the IEEE Southwest Symposium on Image Analysis and Interpretation. 2010. p. 209-212. 5483880 https://doi.org/10.1109/SSIAI.2010.5483880
Jha, Abhinav K. ; Kupinski, Matthew A ; Rodriguez, Jeffrey J ; Stephen, Renu M. ; Stopeck, Alison T. / ADC estimation of lesions in diffusion-weighted MR images : A maximum-likelihood approach. Proceedings of the IEEE Southwest Symposium on Image Analysis and Interpretation. 2010. pp. 209-212
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